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We use a physiologically grounded, unsupervised spiking neural network model of the auditory brain with spike time dependent plasticity learning to demonstrate that plastic auditory cortex is unable to learn even simple auditory object categories when exposed to the raw AN firing input without subcortical preprocessing. We then demonstrate the importance of nonplastic subcortical preprocessing within the cochlear nucleus and the inferior colliculus for stabilizing and denoising AN responses. Such preprocessing enables the plastic auditory cortex to learn efficient robust representations of the auditory object categories. The biological realism of our model makes it suitable for generating neurophysiologically testable hypotheses. <\/jats:p>","DOI":"10.1162\/neco_a_01085","type":"journal-article","created":{"date-parts":[[2018,4,13]],"date-time":"2018-04-13T20:22:15Z","timestamp":1523650935000},"page":"1801-1829","source":"Crossref","is-referenced-by-count":0,"title":["A Computational Account of the Role of Cochlear Nucleus and Inferior Colliculus in Stabilizing Auditory Nerve Firing for Auditory Category Learning"],"prefix":"10.1162","volume":"30","author":[{"given":"Irina","family":"Higgins","sequence":"first","affiliation":[{"name":"Department of Experimental Psychology, University of Oxford, Oxford, OX2 6GG, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Stringer","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, University of Oxford, Oxford, OX2 6GG, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Schnupp","sequence":"additional","affiliation":[{"name":"Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"281","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-81708-3"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-18-07194.2003"},{"key":"B3","first-page":"217","volume":"1","author":"Barlow H. 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