{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T01:16:16Z","timestamp":1768094176755,"version":"3.49.0"},"reference-count":82,"publisher":"MIT Press","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":202,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002701","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2023-00301976"],"award-info":[{"award-number":["RS-2023-00301976"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Korea Basic Science Institute","doi-asserted-by":"publisher","award":["RS-2024-00435727"],"award-info":[{"award-number":["RS-2024-00435727"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT","doi-asserted-by":"publisher","award":["2020K1A3A1A19088932"],"award-info":[{"award-number":["2020K1A3A1A19088932"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT","doi-asserted-by":"publisher","award":["RS-2023-00265406"],"award-info":[{"award-number":["RS-2023-00265406"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT","doi-asserted-by":"publisher","award":["RS-2024-00349515"],"award-info":[{"award-number":["RS-2024-00349515"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT","doi-asserted-by":"publisher","award":["RS-2024-00342897"],"award-info":[{"award-number":["RS-2024-00342897"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT","doi-asserted-by":"publisher","award":["2023R1A2C2005587"],"award-info":[{"award-number":["2023R1A2C2005587"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,8,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Successful encoding of a navigational episode entails the dynamic processing of perceptual information, time-locked to the appearance of salient landmarks and turns along the way. We hypothesized that identical navigational experiences will be represented in a similar manner across individuals and that a deviation from such canonical dynamics in the cortico-hippocampal network may underlie differences in navigational memory across individuals and its decline in aging. 76 participants (42 females) across two age groups (young: 20\u201330 years, aging: 50\u201365 years) watched 24 different 1-minute-long first-person-view virtual navigation videos in the fMRI scanner, followed by a memory question about the traveled path or destination. Canonical dynamics were defined as the averaged neural dynamics across participants during the navigation period for each brain region. First, we found that individual-to-canonical similarity (ICS) was highest in the dorsal\/ventral visual streams and precuneus and was linked to informative navigational events, such as turning or landmark viewing. ICS in the medial temporal lobe (MTL) and the coordinated activity between the hippocampus and canonical cortical dynamics were strongly associated with individual spatial memory performance. Moreover, a reduction in the intersubject functional connectivity between the MTL and the canonical cortical dynamics mediated the effects of aging on cognitive performance, highlighting its role in navigation and episodic memory. Complementary to traditional time-averaged activation measures, canonical neural dynamics may be particularly revealing of how the brain processes information across spatiotemporally extended events.<\/jats:p>","DOI":"10.1162\/imag.a.101","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T20:01:43Z","timestamp":1753214503000},"update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":1,"title":["Canonical cortico-hippocampal dynamics underlie memory of navigational episodes and its early decline in aging"],"prefix":"10.1162","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0579-1759","authenticated-orcid":false,"given":"Jaeseob","family":"Lim","sequence":"first","affiliation":[{"name":"Department of Brain and Cognitive Sciences, Seoul National University, Gwanak-gu, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Eon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Brain and Cognitive Sciences, Seoul National University, Gwanak-gu, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Hun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Brain and Cognitive Sciences, Seoul National University, Gwanak-gu, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7887-6067","authenticated-orcid":false,"given":"Sang Ah","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Brain and Cognitive Sciences, Seoul National University, Gwanak-gu, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"281","published-online":{"date-parts":[[2025,8,18]]},"reference":[{"issue":"3","key":"2025081815553613200_IMAG.a.101-b1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.neuron.2017.06.041","article-title":"Discovering event structure in continuous narrative perception and memory","volume":"95","author":"Baldassano","year":"2017","journal-title":"Neuron"},{"issue":"2\u20133","key":"2025081815553613200_IMAG.a.101-b2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1080\/09541440802598339","article-title":"Ageing, cognition, and neuroscience: An introduction","volume":"21","author":"Ballesteros","year":"2009","journal-title":"European Journal of Cognitive Psychology"},{"issue":"2","key":"2025081815553613200_IMAG.a.101-b3","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.neuron.2023.10.010","article-title":"Hippocampal-cortical interactions during event boundaries support retention of complex narrative events","volume":"112","author":"Barnett","year":"2024","journal-title":"Neuron"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b4","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.neuroimage.2012.07.008","article-title":"Loss of reliable temporal structure in event-related averaging of naturalistic stimuli","volume":"63","author":"Ben-Yakov","year":"2012","journal-title":"NeuroImage"},{"key":"2025081815553613200_IMAG.a.101-b5","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropsychologia.2020.107437","article-title":"Turns during navigation act as boundaries that enhance spatial memory and expand time estimation","volume":"141","author":"Brunec","year":"2020","journal-title":"Neuropsychologia"},{"issue":"Supplement 2","key":"2025081815553613200_IMAG.a.101-b6","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1162\/089892900564046","article-title":"Functional brain imaging of young, nondemented, and demented older adults","volume":"12","author":"Buckner","year":"2000","journal-title":"Journal of Cognitive Neuroscience"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b7","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1196\/annals.1440.002","article-title":"Spatial cognition and the brain","volume":"1124","author":"Burgess","year":"2008","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b8","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nrn1809","article-title":"Neural plasticity in the ageing brain","volume":"7","author":"Burke","year":"2006","journal-title":"Nature Reviews Neuroscience"},{"issue":"11","key":"2025081815553613200_IMAG.a.101-b9","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.1016\/j.neurobiolaging.2015.07.028","article-title":"Idiosyncratic responding during movie-watching predicted by age differences in attentional control","volume":"36","author":"Campbell","year":"2015","journal-title":"Neurobiology of Aging"},{"key":"2025081815553613200_IMAG.a.101-b10","doi-asserted-by":"crossref","first-page":"1012870","DOI":"10.3389\/fnagi.2022.1012870","article-title":"Brain connectivity changes associated with episodic recollection decline in aging: A review of fMRI studies","volume":"14","author":"Cansino","year":"2022","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"21","key":"2025081815553613200_IMAG.a.101-b11","doi-asserted-by":"crossref","first-page":"4912","DOI":"10.1523\/JNEUROSCI.3294-17.2018","article-title":"Encoding of serial order in working memory: Neuronal activity in motor, premotor, and prefrontal cortex during a memory scanning task","volume":"38","author":"Carpenter","year":"2018","journal-title":"Journal of Neuroscience"},{"key":"2025081815553613200_IMAG.a.101-b12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1162\/imag_a_00128","article-title":"High performers demonstrate greater neural synchrony than low performers across behavioral domains","volume":"2","author":"Chamberlain","year":"2024","journal-title":"Imaging Neuroscience"},{"key":"2025081815553613200_IMAG.a.101-b13","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3389\/fpsyg.2012.00304","article-title":"From objects to landmarks: The function of visual location information in spatial navigation","volume":"3","author":"Chan","year":"2012","journal-title":"Frontiers in Psychology"},{"key":"2025081815553613200_IMAG.a.101-b14","article-title":"A reduced-dimension fMRI shared response model","volume":"28","author":"Chen","year":"2015","journal-title":"Advances in Neural Information Processing Systems"},{"issue":"3","key":"2025081815553613200_IMAG.a.101-b15","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"Corbetta","year":"2002","journal-title":"Nature Reviews Neuroscience"},{"issue":"5237","key":"2025081815553613200_IMAG.a.101-b16","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1126\/science.270.5237.802","article-title":"Superior parietal cortex activation during spatial attention shifts and visual feature conjunction","volume":"270","author":"Corbetta","year":"1995","journal-title":"Science"},{"key":"2025081815553613200_IMAG.a.101-b17","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.brainres.2008.01.105","article-title":"Covert orienting of attention and overt eye movements activate identical brain regions","volume":"1204","author":"De Haan","year":"2008","journal-title":"Brain Research"},{"issue":"4","key":"2025081815553613200_IMAG.a.101-b18","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.tins.2024.02.001","article-title":"The \u2018middle-aging\u2019 brain","volume":"47","author":"Dohm-Hansen","year":"2024","journal-title":"Trends in Neurosciences"},{"issue":"7","key":"2025081815553613200_IMAG.a.101-b19","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.neuron.2023.03.001","article-title":"Spatial navigation and memory: A review of the similarities and differences relevant to brain models and age","volume":"111","author":"Ekstrom","year":"2023","journal-title":"Neuron"},{"key":"2025081815553613200_IMAG.a.101-b20","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.cobeha.2017.06.005","article-title":"Human spatial navigation: Representations across dimensions and scales","volume":"17","author":"Ekstrom","year":"2017","journal-title":"Current Opinion in Behavioral Sciences"},{"issue":"9","key":"2025081815553613200_IMAG.a.101-b21","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/hipo.22750","article-title":"Space, time, and episodic memory: The hippocampus is all over the cognitive map","volume":"28","author":"Ekstrom","year":"2018","journal-title":"Hippocampus"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b22","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0896-6273(00)80758-8","article-title":"The parahippocampal place area: Recognition, navigation, or encoding?","volume":"23","author":"Epstein","year":"1999","journal-title":"Neuron"},{"issue":"23","key":"2025081815553613200_IMAG.a.101-b23","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.1523\/JNEUROSCI.0799-07.2007","article-title":"Where am I now? Distinct roles for parahippocampal and retrosplenial cortices in place recognition","volume":"27","author":"Epstein","year":"2007","journal-title":"Journal of Neuroscience"},{"issue":"11","key":"2025081815553613200_IMAG.a.101-b24","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1038\/nn.4656","article-title":"The cognitive map in humans: Spatial navigation and beyond","volume":"20","author":"Epstein","year":"2017","journal-title":"Nature Neuroscience"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41592-018-0235-4","article-title":"fMRIPrep: A robust preprocessing pipeline for functional MRI","volume":"16","author":"Esteban","year":"2019","journal-title":"Nature Methods"},{"issue":"3","key":"2025081815553613200_IMAG.a.101-b26","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S0165-0173(99)00017-X","article-title":"Involvement of hippocampal synaptic plasticity in age-related memory decline","volume":"30","author":"Foster","year":"1999","journal-title":"Brain Research Reviews"},{"issue":"27","key":"2025081815553613200_IMAG.a.101-b27","doi-asserted-by":"crossref","first-page":"9673","DOI":"10.1073\/pnas.0504136102","article-title":"The human brain is intrinsically organized into dynamic, anticorrelated functional networks","volume":"102","author":"Fox","year":"2005","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"2025081815553613200_IMAG.a.101-b28","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.neurobiolaging.2018.07.025","article-title":"Age-related differences in information processing during movie watching","volume":"72","author":"Geerligs","year":"2018","journal-title":"Neurobiology of Aging"},{"issue":"7615","key":"2025081815553613200_IMAG.a.101-b29","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nature18933","article-title":"A multi-modal parcellation of human cerebral cortex","volume":"536","author":"Glasser","year":"2016","journal-title":"Nature"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b30","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0166-2236(92)90344-8","article-title":"Separate visual pathways for perception and action","volume":"15","author":"Goodale","year":"1992","journal-title":"Trends in Neurosciences"},{"issue":"42","key":"2025081815553613200_IMAG.a.101-b31","doi-asserted-by":"crossref","first-page":"14123","DOI":"10.1523\/JNEUROSCI.0801-15.2015","article-title":"Hippocampal volume reduction in humans predicts impaired allocentric spatial memory in virtual-reality navigation","volume":"35","author":"Guderian","year":"2015","journal-title":"Journal of Neuroscience"},{"issue":"5","key":"2025081815553613200_IMAG.a.101-b32","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S0896-6273(03)00095-3","article-title":"The well-worn route and the path less traveled: Distinct neural bases of route following and wayfinding in humans","volume":"37","author":"Hartley","year":"2003","journal-title":"Neuron"},{"issue":"3","key":"2025081815553613200_IMAG.a.101-b33","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.neuron.2007.12.009","article-title":"Enhanced intersubject correlations during movie viewing correlate with successful episodic encoding","volume":"57","author":"Hasson","year":"2008","journal-title":"Neuron"},{"issue":"2","key":"2025081815553613200_IMAG.a.101-b34","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.tics.2011.12.007","article-title":"Brain-to-brain coupling: A mechanism for creating and sharing a social world","volume":"16","author":"Hasson","year":"2012","journal-title":"Trends in Cognitive Sciences"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b35","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.tics.2009.10.011","article-title":"Reliability of cortical activity during natural stimulation","volume":"14","author":"Hasson","year":"2010","journal-title":"Trends in Cognitive Sciences"},{"issue":"5664","key":"2025081815553613200_IMAG.a.101-b36","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1126\/science.1089506","article-title":"Intersubject synchronization of cortical activity during natural vision","volume":"303","author":"Hasson","year":"2004","journal-title":"Science"},{"issue":"2","key":"2025081815553613200_IMAG.a.101-b37","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.neuron.2011.08.026","article-title":"A common, high-dimensional model of the representational space in human ventral temporal cortex","volume":"72","author":"Haxby","year":"2011","journal-title":"Neuron"},{"issue":"3","key":"2025081815553613200_IMAG.a.101-b38","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0304-3940(01)01920-6","article-title":"Age related signal decrease in functional magnetic resonance imaging during motor stimulation in humans","volume":"308","author":"Hesselmann","year":"2001","journal-title":"Neuroscience Letters"},{"issue":"10","key":"2025081815553613200_IMAG.a.101-b39","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/hipo.23624","article-title":"Scene construction processes in the anterior hippocampus during temporal episodic memory retrieval","volume":"34","author":"Hwang","year":"2024","journal-title":"Hippocampus"},{"issue":"3","key":"2025081815553613200_IMAG.a.101-b40","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1111\/j.1460-9568.2007.05371.x","article-title":"Retrosplenial and hippocampal brain regions in human navigation: Complementary functional contributions to the formation and use of cognitive maps","volume":"25","author":"Iaria","year":"2007","journal-title":"European Journal of Neuroscience"},{"key":"2025081815553613200_IMAG.a.101-b41","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.neuroimage.2016.07.008","article-title":"Path integration in 3D from visual motion cues: A human fMRI study","volume":"142","author":"Indovina","year":"2016","journal-title":"NeuroImage"},{"key":"2025081815553613200_IMAG.a.101-b42","doi-asserted-by":"crossref","first-page":"120390","DOI":"10.1016\/j.neuroimage.2023.120390","article-title":"Inter-subject correlation during long narratives reveals widespread neural correlates of reading ability","volume":"282","author":"Jangraw","year":"2023","journal-title":"NeuroImage"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b43","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.neuroimage.2010.03.083","article-title":"A neural wayfinding mechanism adjusts for ambiguous landmark information","volume":"52","author":"Janzen","year":"2010","journal-title":"NeuroImage"},{"issue":"6","key":"2025081815553613200_IMAG.a.101-b44","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/nn1257","article-title":"Selective neural representation of objects relevant for navigation","volume":"7","author":"Janzen","year":"2004","journal-title":"Nature Neuroscience"},{"issue":"1908","key":"2025081815553613200_IMAG.a.101-b45","doi-asserted-by":"crossref","first-page":"20191016","DOI":"10.1098\/rspb.2019.1016","article-title":"Backtracking during navigation is correlated with enhanced anterior cingulate activity and suppression of alpha oscillations and the \u2018default-mode\u2019 network","volume":"286","author":"Javadi","year":"2019","journal-title":"Proceedings of the Royal Society B"},{"issue":"6","key":"2025081815553613200_IMAG.a.101-b46","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.jphysparis.2013.04.002","article-title":"Maps of space in human frontoparietal cortex","volume":"107","author":"Jerde","year":"2013","journal-title":"Journal of Physiology-Paris"},{"issue":"10","key":"2025081815553613200_IMAG.a.101-b47","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.1523\/JNEUROSCI.2942-15.2016","article-title":"Attention strongly modulates reliability of neural responses to naturalistic narrative stimuli","volume":"36","author":"Ki","year":"2016","journal-title":"Journal of Neuroscience"},{"issue":"8","key":"2025081815553613200_IMAG.a.101-b48","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112989","article-title":"Hippocampal orchestration of associative and sequential memory networks for episodic retrieval","volume":"42","author":"Kim","year":"2023","journal-title":"Cell Reports"},{"issue":"4","key":"2025081815553613200_IMAG.a.101-b49","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1152\/physrev.00021.2010","article-title":"Framing spatial cognition: Neural representations of proximal and distal frames of reference and their roles in navigation","volume":"91","author":"Knierim","year":"2011","journal-title":"Physiological Reviews"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b50","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1523\/JNEUROSCI.1498-18.2018","article-title":"The relationship between age, neural differentiation, and memory performance","volume":"39","author":"Koen","year":"2019","journal-title":"Journal of Neuroscience"},{"key":"2025081815553613200_IMAG.a.101-b51","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.cobeha.2020.01.006","article-title":"Age-related neural dedifferentiation and cognition","volume":"32","author":"Koen","year":"2020","journal-title":"Current Opinion in Behavioral Sciences"},{"issue":"5","key":"2025081815553613200_IMAG.a.101-b52","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.neuron.2017.06.037","article-title":"The aging navigational system","volume":"95","author":"Lester","year":"2017","journal-title":"Neuron"},{"issue":"43","key":"2025081815553613200_IMAG.a.101-b53","doi-asserted-by":"crossref","first-page":"15264","DOI":"10.1523\/JNEUROSCI.3634-11.2011","article-title":"Cognitive mappers to creatures of habit: Differential engagement of place and response learning mechanisms predicts human navigational behavior","volume":"31","author":"Marchette","year":"2011","journal-title":"Journal of Neuroscience"},{"key":"2025081815553613200_IMAG.a.101-b54","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/0166-2236(83)90190-X","article-title":"Object vision and spatial vision: Two cortical pathways","volume":"6","author":"Mishkin","year":"1983","journal-title":"Trends in Neurosciences"},{"key":"2025081815553613200_IMAG.a.101-b55","doi-asserted-by":"crossref","first-page":"2398212818757098","DOI":"10.1177\/2398212818757098","article-title":"Retrosplenial cortex and its role in spatial cognition","volume":"2","author":"Mitchell","year":"2018","journal-title":"Brain and Neuroscience Advances"},{"issue":"5","key":"2025081815553613200_IMAG.a.101-b56","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1037\/0735-7044.116.5.851","article-title":"Effects of age on virtual environment place navigation and allocentric cognitive mapping","volume":"116","author":"Moffat","year":"2002","journal-title":"Behavioral Neuroscience"},{"issue":"5","key":"2025081815553613200_IMAG.a.101-b57","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0197-4580(01)00251-2","article-title":"Age differences in spatial memory in a virtual environment navigation task","volume":"22","author":"Moffat","year":"2001","journal-title":"Neurobiology of Aging"},{"issue":"6","key":"2025081815553613200_IMAG.a.101-b58","first-page":"667","article-title":"Measuring shared responses across subjects using intersubject correlation","volume":"14","author":"Nastase","year":"2019","journal-title":"Social Cognitive and Affective Neuroscience"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b59","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/joim.12533","article-title":"Functional brain imaging of episodic memory decline in ageing","volume":"281","author":"Nyberg","year":"2017","journal-title":"Journal of Internal Medicine"},{"issue":"5","key":"2025081815553613200_IMAG.a.101-b60","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.tics.2012.04.005","article-title":"Memory aging and brain maintenance","volume":"16","author":"Nyberg","year":"2012","journal-title":"Trends in Cognitive Sciences"},{"issue":"2","key":"2025081815553613200_IMAG.a.101-b61","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1176\/appi.ajp.160.2.379","article-title":"Parahippocampal volume deficits in subjects with aging-associated cognitive decline","volume":"160","author":"Pantel","year":"2003","journal-title":"American Journal of Psychiatry"},{"issue":"4","key":"2025081815553613200_IMAG.a.101-b62","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.3233\/JAD-200892","article-title":"The fragility of temporal memory in Alzheimer\u2019s disease","volume":"79","author":"Park","year":"2021","journal-title":"Journal of Alzheimer\u2019s Disease"},{"issue":"4","key":"2025081815553613200_IMAG.a.101-b63","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1523\/JNEUROSCI.3885-10.2011","article-title":"Disentangling scene content from spatial boundary: Complementary roles for the parahippocampal place area and lateral occipital complex in representing real-world scenes","volume":"31","author":"Park","year":"2011","journal-title":"Journal of Neuroscience"},{"issue":"11","key":"2025081815553613200_IMAG.a.101-b64","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1162\/jocn_a_02039","article-title":"Cognotyping by what\u2013where\u2013when retrieval reveals the potential role of temporal memory and its neural correlates in understanding individual differences across aging and Alzheimer disease","volume":"35","author":"Park","year":"2023","journal-title":"Journal of Cognitive Neuroscience"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b65","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0244-17.2017","article-title":"The variability of neural responses to naturalistic videos change with age and sex","volume":"5","author":"Petroni","year":"2018","journal-title":"ENeuro"},{"issue":"3","key":"2025081815553613200_IMAG.a.101-b66","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","article-title":"Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion","volume":"59","author":"Power","year":"2012","journal-title":"Neuroimage"},{"issue":"2","key":"2025081815553613200_IMAG.a.101-b67","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1073\/pnas.98.2.676","article-title":"A default mode of brain function","volume":"98","author":"Raichle","year":"2001","journal-title":"Proceedings of the National Academy of Sciences"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b68","doi-asserted-by":"crossref","first-page":"3980","DOI":"10.1038\/s41467-020-17713-4","article-title":"Aging alters neural activity at event boundaries in the hippocampus and posterior medial network","volume":"11","author":"Reagh","year":"2020","journal-title":"Nature Communications"},{"issue":"7","key":"2025081815553613200_IMAG.a.101-b69","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/hipo.10218","article-title":"I have often walked down this street before\u201d: fMRI studies on the hippocampus and other structures during mental navigation of an old environment","volume":"14","author":"Rosenbaum","year":"2004","journal-title":"Hippocampus"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b70","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1212\/WNL.48.1.173","article-title":"Age-related reduction in functional MRI response to photic stimulation","volume":"48","author":"Ross","year":"1997","journal-title":"Neurology"},{"issue":"17","key":"2025081815553613200_IMAG.a.101-b71","doi-asserted-by":"crossref","first-page":"6769","DOI":"10.1523\/JNEUROSCI.17-17-06769.1997","article-title":"The effect of aging on experience-dependent plasticity of hippocampal place cells","volume":"17","author":"Shen","year":"1997","journal-title":"Journal of Neuroscience"},{"issue":"35","key":"2025081815553613200_IMAG.a.101-b72","doi-asserted-by":"crossref","first-page":"e2308951120","DOI":"10.1073\/pnas.2308951120","article-title":"Intersubject similarity in neural representations underlies shared episodic memory content","volume":"120","author":"Sheng","year":"2023","journal-title":"Proceedings of the National Academy of Sciences"},{"issue":"4","key":"2025081815553613200_IMAG.a.101-b73","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1152\/jn.2002.88.4.2047","article-title":"Spatial attention and memory versus motor preparation: Premotor cortex involvement as revealed by fMRI","volume":"88","author":"Simon","year":"2002","journal-title":"Journal of Neurophysiology"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b74","doi-asserted-by":"crossref","first-page":"12141","DOI":"10.1038\/ncomms12141","article-title":"Dynamic reconfiguration of the default mode network during narrative comprehension","volume":"7","author":"Simony","year":"2016","journal-title":"Nature Communications"},{"key":"2025081815553613200_IMAG.a.101-b75","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2307\/270723","article-title":"Asymptotic confidence intervals for indirect effects in structural equation models","volume":"13","author":"Sobel","year":"1982","journal-title":"Sociological Methodology"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b76","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/hipo.23259","article-title":"Age-related alterations in functional connectivity along the longitudinal axis of the hippocampus and its subfields","volume":"31","author":"Stark","year":"2021","journal-title":"Hippocampus"},{"key":"2025081815553613200_IMAG.a.101-b77","doi-asserted-by":"crossref","first-page":"661514","DOI":"10.3389\/fnagi.2021.661514","article-title":"Predicting age from behavioral test performance for screening early onset of cognitive decline","volume":"13","author":"Statsenko","year":"2021","journal-title":"Frontiers in Aging Neuroscience"},{"key":"2025081815553613200_IMAG.a.101-b78","doi-asserted-by":"crossref","first-page":"118081","DOI":"10.1016\/j.neuroimage.2021.118081","article-title":"The parahippocampal place area and hippocampus encode the spatial significance of landmark objects","volume":"236","author":"Sun","year":"2021","journal-title":"NeuroImage"},{"issue":"1","key":"2025081815553613200_IMAG.a.101-b79","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1093\/cercor\/bhm049","article-title":"Beyond superior temporal cortex: Intersubject correlations in narrative speech comprehension","volume":"18","author":"Wilson","year":"2008","journal-title":"Cerebral Cortex"},{"issue":"10","key":"2025081815553613200_IMAG.a.101-b80","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/nn.2189","article-title":"Spatial updating: How the brain keeps track of changing object locations during observer motion","volume":"11","author":"Wolbers","year":"2008","journal-title":"Nature Neuroscience"},{"issue":"35","key":"2025081815553613200_IMAG.a.101-b81","doi-asserted-by":"crossref","first-page":"9408","DOI":"10.1523\/JNEUROSCI.2146-07.2007","article-title":"Differential recruitment of the hippocampus, medial prefrontal cortex, and the human motion complex during path integration in humans","volume":"27","author":"Wolbers","year":"2007","journal-title":"Journal of Neuroscience"},{"issue":"4","key":"2025081815553613200_IMAG.a.101-b82","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/j.neuroimage.2010.05.074","article-title":"Persistent posterior and transient anterior medial temporal lobe activity during navigation","volume":"52","author":"Xu","year":"2010","journal-title":"Neuroimage"}],"container-title":["Imaging Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/direct.mit.edu\/imag\/article-pdf\/doi\/10.1162\/IMAG.a.101\/2537957\/imag.a.101.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/direct.mit.edu\/imag\/article-pdf\/doi\/10.1162\/IMAG.a.101\/2537957\/imag.a.101.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T19:55:50Z","timestamp":1755546950000},"score":1,"resource":{"primary":{"URL":"https:\/\/direct.mit.edu\/imag\/article\/doi\/10.1162\/IMAG.a.101\/131886\/Canonical-cortico-hippocampal-dynamics-underlie"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":82,"URL":"https:\/\/doi.org\/10.1162\/imag.a.101","relation":{},"ISSN":["2837-6056"],"issn-type":[{"value":"2837-6056","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025]]},"published":{"date-parts":[[2025]]},"article-number":"IMAG.a.101"}}