{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T20:17:12Z","timestamp":1777321032041,"version":"3.51.4"},"reference-count":30,"publisher":"MIT Press","license":[{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"vor","delay-in-days":238,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014013","name":"UK Research and Innovation Department (UKRI) via the Engineering and\nPhysical Sciences Research Council (EPSRC) as EPSRC","doi-asserted-by":"publisher","award":["EP\/L015358\/1"],"award-info":[{"award-number":["EP\/L015358\/1"]}],"id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UKRI Future Leaders Fellowships","doi-asserted-by":"publisher","award":["MR\/T04294X\/1"],"award-info":[{"award-number":["MR\/T04294X\/1"]}],"id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UKRI Future Leaders Fellowships","doi-asserted-by":"publisher","award":["MR\/V026569\/1"],"award-info":[{"award-number":["MR\/V026569\/1"]}],"id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIHR UCLH\/UCL Biomedical Research Centre"}],"content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>MRI-based delineation of brain tissue removed by epilepsy surgery can be challenging due to post-operative brain shift. In consequence, most studies use manual approaches which are prohibitively time-consuming for large sample sizes, require expertise, and can be prone to errors. We propose RAMPS (Resections And Masks in Preoperative Space), an automated pipeline to generate a 3D resection mask of pre-operative tissue. Our pipeline leverages existing software including FreeSurfer, SynthStrip, Sythnseg and ANTs to generate a mask in the same space as the patient\u2019s pre-operative T1 weighted MRI. We compare our automated masks against manually drawn masks and two other existing pipelines (Epic-CHOP and ResectVol). Comparing to manual masks (N = 87), RAMPS achieved a median (IQR) dice similarity of 0.86 (0.078) in temporal lobe resections, and 0.72 (0.32) in extratemporal resections. In comparison to other pipelines, RAMPS had higher dice similarities (N = 62) (RAMPS: 0.86, Epic-CHOP: 0.72, ResectVol: 0.72). We release a user-friendly, easy-to-use pipeline, RAMPS, open source for accurate delineation of resected tissue.<\/jats:p>","DOI":"10.1162\/imag.a.147","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:01:16Z","timestamp":1756324876000},"update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":4,"title":["Automated generation of epilepsy surgery resection masks: The RAMPS pipeline"],"prefix":"10.1162","volume":"3","author":[{"given":"Callum","family":"Simpson","sequence":"first","affiliation":[{"name":"CNNP Lab (www.cnnp-lab.com), Interdisciplinary Computing and Complex BioSystems Group, School of Computing, Newcastle University, Newcastle upon Tyne, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard","family":"Hall","sequence":"additional","affiliation":[{"name":"CNNP Lab (www.cnnp-lab.com), Interdisciplinary Computing and Complex BioSystems Group, School of Computing, Newcastle University, Newcastle upon Tyne, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S.","family":"Duncan","sequence":"additional","affiliation":[{"name":"UCL Queen Square Institute of Neurology, Queen Square, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujiang","family":"Wang","sequence":"additional","affiliation":[{"name":"CNNP Lab (www.cnnp-lab.com), Interdisciplinary Computing and Complex BioSystems Group, School of Computing, Newcastle University, Newcastle upon Tyne, United Kingdom"},{"name":"UCL Queen Square Institute of Neurology, Queen Square, London, United Kingdom"},{"name":"Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter N.","family":"Taylor","sequence":"additional","affiliation":[{"name":"CNNP Lab (www.cnnp-lab.com), Interdisciplinary Computing and 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