{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T21:51:17Z","timestamp":1792705877482,"version":"4.5.0"},"reference-count":59,"publisher":"MIT Press - Journals","issue":"3","content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Depth information is necessary for adjusting the hand to the three-dimensional (3-D) shape of an object to grasp it. The transformation of visual information into appropriate distal motor commands is critically dependent on the anterior intraparietal area (AIP) and the ventral premotor cortex (area F5), particularly the F5p sector. Recent studies have demonstrated that both AIP and the F5a sector of the ventral premotor cortex contain neurons that respond selectively to disparity-defined 3-D shape. To investigate the neural coding of 3-D shape and the behavioral role of 3-D shape-selective neurons in these two areas, we recorded single-cell activity in AIP and F5a during passive fixation of curved surfaces and during grasping of real-world objects. Similar to those in AIP, F5a neurons were either first- or second-order disparity selective, frequently showed selectivity for discrete approximations of smoothly curved surfaces that contained disparity discontinuities, and exhibited mostly monotonic tuning for the degree of disparity variation. Furthermore, in both areas, 3-D shape-selective neurons were colocalized with neurons that were active during grasping of real-world objects. Thus, area AIP and F5a contain highly similar representations of 3-D shape, which is consistent with the proposed transfer of object information from AIP to the motor system through the ventral premotor cortex.<\/jats:p>","DOI":"10.1162\/jocn_a_00332","type":"journal-article","created":{"date-parts":[[2012,11,28]],"date-time":"2012-11-28T15:43:00Z","timestamp":1354117380000},"page":"352-364","update-policy":"https:\/\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":43,"title":["Three-dimensional Shape Coding in Grasping Circuits: A Comparison between the Anterior Intraparietal Area and Ventral Premotor Area F5a"],"prefix":"10.1162","volume":"25","author":[{"given":"Tom","family":"Theys","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Pani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"van Loon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Goffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Janssen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"281","published-online":{"date-parts":[[2013,3,1]]},"reference":[{"key":"2021072913271439900_R1","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1111\/j.1460-9568.2007.05365.x","article-title":"Differential cortical activity for precision and whole-hand visually guided grasping in humans.","volume":"25","author":"Begliomini","year":"2007","journal-title":"European Journal of Neuroscience"},{"key":"2021072913271439900_R2","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1212\/WNL.50.5.1253","article-title":"Human anterior intraparietal area subserves prehension: A combined lesion and functional MRI activation study.","volume":"50","author":"Binkofski","year":"1998","journal-title":"Neurology"},{"key":"2021072913271439900_R3","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0896-6273(01)00362-2","article-title":"Hierarchical processing of tactile shape in the human brain.","volume":"31","author":"Bodegard","year":"2001","journal-title":"Neuron"},{"key":"2021072913271439900_R4","doi-asserted-by":"crossref","first-page":"e424","DOI":"10.1371\/journal.pone.0000424","article-title":"fMRI reveals a dissociation between grasping and perceiving the size of real 3-D objects.","volume":"2","author":"Cavina-Pratesi","year":"2007","journal-title":"PLoS One"},{"key":"2021072913271439900_R5","doi-asserted-by":"crossref","first-page":"10306","DOI":"10.1523\/JNEUROSCI.2023-10.2010","article-title":"Functional magnetic resonance imaging reveals the neural substrates of arm transport and grip formation in reach-to-grasp actions in humans.","volume":"30","author":"Cavina-Pratesi","year":"2010","journal-title":"Journal of Neuroscience"},{"key":"2021072913271439900_R6","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s00221-003-1591-5","article-title":"Visually guided grasping produces fMRI activation in dorsal but not ventral stream brain areas.","volume":"153","author":"Culham","year":"2003","journal-title":"Experimental Brain Research"},{"key":"2021072913271439900_R7","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0959-4388(00)00191-4","article-title":"Neuroimaging of cognitive functions in human parietal cortex.","volume":"11","author":"Culham","year":"2001","journal-title":"Current Opinion in Neurobiology"},{"key":"2021072913271439900_R8","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.cub.2009.11.063","article-title":"Causal connectivity between the human anterior intraparietal area and premotor cortex during grasp.","volume":"20","author":"Davare","year":"2010","journal-title":"Current Biology"},{"key":"2021072913271439900_R9","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1007\/BF00227950","article-title":"The perception and prehension of objects oriented in the depth plane. 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