{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:51:09Z","timestamp":1774486269176,"version":"3.50.1"},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Early Sci Med"],"published-print":{"date-parts":[[2014,9,25]]},"abstract":"<jats:p>In the seventeenth century, the discrepancy between the taste of some drugs and their effects on the body was used to criticize Galenic medicine. In this paper, I argue that such contradictions were brought to light by the sixteenth-century study of drug properties within the Galenic tradition itself. Investigating how the taste of a drug corresponded to the effects it had on the body became a core problem for maintaining a medical practice that was both rational and effective. I discuss four physicians, connected to the University of Leiden, who attempted to understand drug properties, including taste, within a Galenic framework. The sixteenth-century discussions about the relationship between the senses, reason and experience, will help us understand the seventeenth-century criticism of Galenic medicine and the importance of discussions about <jats:italic>materia medica<\/jats:italic> for ideas regarding the properties of matter proposed in this period.\u2029<\/jats:p>","DOI":"10.1163\/15733823-00194p01","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T13:41:43Z","timestamp":1412343703000},"page":"287-316","source":"Crossref","is-referenced-by-count":4,"title":["The Trouble with Opium. Taste, Reason and Experience in Late Galenic Pharmacology with Special Regard to the University of Leiden (1575\u20131625)"],"prefix":"10.1163","volume":"19","author":[{"given":"Saskia","family":"Klerk","sequence":"first","affiliation":[{"name":"Utrecht University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","container-title":["Early Science and Medicine"],"original-title":[],"link":[{"URL":"https:\/\/brill.com\/view\/journals\/esm\/19\/4\/article-p287_1.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/data.brill.com\/files\/journals\/15733823_019_04_s001_text.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T10:56:07Z","timestamp":1559559367000},"score":1,"resource":{"primary":{"URL":"https:\/\/brill.com\/view\/journals\/esm\/19\/4\/article-p287_1.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,25]]},"references-count":0,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1163\/15733823-00194p01","relation":{},"ISSN":["1383-7427","1573-3823"],"issn-type":[{"value":"1383-7427","type":"electronic"},{"value":"1573-3823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,25]]}}}