{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:12:44Z","timestamp":1778728364689,"version":"3.51.4"},"reference-count":106,"publisher":"Walter de Gruyter GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Benef. Microbes"],"published-print":{"date-parts":[[2026,5,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The implication of gut microbiota in the pathophysiology of type 2 diabetes, one of the major health concerns worldwide, has demonstrated the benefits of using probiotics to improve dysbiosis. Facing the lack of defined research strategy to found and qualify bacterial with real antidiabetic activity, we have developed a program to identify, select and validate novel strains able to improve metabolic alterations in type 2 diabetes. Among potential candidates, we identified\n                    <jats:italic>Bacteroides faecichinchillae<\/jats:italic>\n                    (named BAfa hereafter), and the present work presents the validation of the antidiabetic potential of the ST37 (DSMZ 26883) BAfa strain in mice fed a high-fat high-sucrose (HFS) diet for 10 weeks followed by 4 weeks of treatment. Daily gavage with live, but not heat inactivated, BAfa improved glucose tolerance, fasting hyperinsulinemia and liver triglyceride content in HFS fed mice. Furthermore, these beneficial effects were retained after lyophilization. Using this preclinical model, we characterised BAfa mechanism of action, showing that four weeks of treatment was associated with reduced hepatic accumulation of ceramides, key actors of insulin resistance. The underlying mechanism could be related to BAfa-induced changes in the intestinal bile acid profile and inhibition of the Fxr-Fgf15 pathway in the ileum. BAfa supplementation during 4 weeks in HFS fed mice was also associated with mild modifications of gut microbiota composition, with the upregulation of several species known for their beneficial metabolic actions (such as\n                    <jats:italic>Lactobacillus johnsonii<\/jats:italic>\n                    ,\n                    <jats:italic>Limosilactobacillus reutei<\/jats:italic>\n                    ,\n                    <jats:italic>Roseburia<\/jats:italic>\n                    ,\n                    <jats:italic>Turicimonas muris<\/jats:italic>\n                    ,\n                    <jats:italic>Phocaeicola dorei<\/jats:italic>\n                    or\n                    <jats:italic>Akkermansia muciniphila<\/jats:italic>\n                    ) and for being up-regulated during metformin treatment. Altogether, these data indicate that BAfa and related\n                    <jats:italic>B. faecichinchillae<\/jats:italic>\n                    strains could be considered for developing next-generation probiotics to treat type 2 diabetes, potentially in combination with the anti-diabetic drug metformin.\n                  <\/jats:p>","DOI":"10.1163\/18762891-bja00118","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:05:07Z","timestamp":1778727907000},"page":"1-17","source":"Crossref","is-referenced-by-count":0,"title":["Gut commensal Bacteroides faecichinchillae, a potential novel candidate of next-generation probiotics targeting type 2 diabetes"],"prefix":"10.1163","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9879-4731","authenticated-orcid":true,"given":"M.","family":"Godet","sequence":"first","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Delmas","sequence":"additional","affiliation":[{"name":"UMR MEDIS, INRAE U454, Universite\u0301 Clermont-Auvergne, Saint-Gene\u0300s-Champanelle, 63122, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ge\u0301rard","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2291-7691","authenticated-orcid":true,"given":"E.","family":"Meugnier","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bravard","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Pinteur","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Vega","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0456-7007","authenticated-orcid":true,"given":"N.","family":"Bendridi","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9535-2567","authenticated-orcid":true,"given":"D.","family":"Cheillan","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"},{"name":"Service de Biochimie et Biologie Mole\u0301culaire, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, 69500 Bron, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8025-8575","authenticated-orcid":true,"given":"S.","family":"Fourati","sequence":"additional","affiliation":[{"name":"Sorbonne Universite\u0301, Centre de Recherche Saint-Antoine, INSERM U938, 75012 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Rainteau","sequence":"additional","affiliation":[{"name":"Sorbonne Universite\u0301, Centre de Recherche Saint-Antoine, INSERM U938, 75012 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2112-5254","authenticated-orcid":true,"given":"M.","family":"Le Barz","sequence":"additional","affiliation":[{"name":"Lallemand Health Solutions, 31702 Blagnac, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3939-4118","authenticated-orcid":true,"given":"S.","family":"Binda","sequence":"additional","affiliation":[{"name":"Lallemand Health Solutions, 31702 Blagnac, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4542-3053","authenticated-orcid":true,"given":"F.","family":"Leulier","sequence":"additional","affiliation":[{"name":"Institut de Ge\u0301nomique Fonctionnelle de Lyon, Ecole Normale Supe\u0301rieure de Lyon, CNRS UMR5242, UCBL Lyon-1, 69007 Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7541-4417","authenticated-orcid":true,"given":"A.","family":"Bernalier-Donadille","sequence":"additional","affiliation":[{"name":"UMR MEDIS, INRAE U454, Universite\u0301 Clermont-Auvergne, Saint-Gene\u0300s-Champanelle, 63122, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9467-0317","authenticated-orcid":true,"given":"H.","family":"Vidal","sequence":"additional","affiliation":[{"name":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https:\/\/dx.doi.org\/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"R000001","series-title":"Molecular Biology Reports","article-title":"Next-generation probiotics: the upcoming biotherapeutics","volume":"51","author":"Al-Fakhrany, O.M.","unstructured":"Al-Fakhrany, O.M. and Elekhnawy, E., 2024. Next-generation probiotics: the upcoming biotherapeutics. Molecular Biology Reports 51: 505. https:\/\/doi.org\/10.1007\/s11033-024-09398-5"},{"key":"R000002","series-title":"Gut Microbes","article-title":"Inhibition of intestinal FXR activity as a possible mechanism for the beneficial effects of a probiotic mix supplementation on lipid metabolism alterations and weight gain in mice fed a high fat diet","volume":"15","author":"Beau, A.","unstructured":"Beau, A., Benoit, B., Le Barz, M., Meugnier, E., Penhoat, A., Calzada, C., Pinteur, C., Loizon, E., Chanon, S., Vieille-Marchiset, A., Sauvinet, V., Godet, M., Laugerette, F., Holowacz, S., Jacouton, E., Michalski, M.-C. and Vidal, H., 2023. Inhibition of intestinal FXR activity as a possible mechanism for the beneficial effects of a probiotic mix supplementation on lipid metabolism alterations and weight gain in mice fed a high fat diet. Gut Microbes 15: 2281015. https:\/\/doi.org\/10.1080\/19490976.2023.2281015"},{"key":"R000003","series-title":"Science Reports","article-title":"Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice","volume":"11","author":"Bravard, A.","unstructured":"Bravard, A., Ge\u0301rard, C., Defois, C., Benoit, B., Makki, K., Meugnier, E., Rainteau, D., Rieusset, J., Godet, M. and Vidal, H., 2021. Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice. Science Reports 11: 16684. https:\/\/doi.org\/10.1038\/s41598-021-95117-0"},{"key":"R000004","series-title":"Cell Host and Microbe","first-page":"668","article-title":"Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis","volume":"25","author":"Brown, E.M.","unstructured":"Brown, E.M., Ke, X., Hitchcock, D., Jeanfavre, S., Avila-Pacheco, J., Nakata, T., Arthur, T.D., Fornelos, N., Heim, C., Franzosa, E.A., Watson, N., Huttenhower, C., Haiser, H.J., Dillow, G., Graham, D.B., Finlay, B.B., Kostic, A.D., Porter, J.A., Vlamakis, H., Clish, C.B. and Xavier, R.J., 2019. Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis. Cell Host and Microbe 25: 668-680.e7. https:\/\/doi.org\/10.1016\/j.chom.2019.04.002"},{"key":"R000005","series-title":"Nature Reviews Endocrinology","first-page":"74","article-title":"The gut microbiota manages host metabolism","volume":"10","author":"Cani, P.D.","unstructured":"Cani, P.D., 2014. The gut microbiota manages host metabolism. Nature Reviews Endocrinology 10: 74-76. https:\/\/doi.org\/10.1038\/nrendo.2013.240"},{"key":"R000006","series-title":"Science Reports","article-title":"Gut commensal Kineothrix alysoides mitigates liver dysfunction by restoring lipid metabolism and gut microbial balance","volume":"13","author":"Choi, K.J.","unstructured":"Choi, K.J., Yoon, M.Y., Kim, J.-E. and Yoon, S.S., 2023. Gut commensal Kineothrix alysoides mitigates liver dysfunction by restoring lipid metabolism and gut microbial balance. Science Reports 13: 14668. https:\/\/doi.org\/10.1038\/s41598-023-41160-y"},{"key":"R000007","series-title":"Journal of Microbiological Methods","first-page":"133","article-title":"A simple and versatile micro-computer program for the determination of \u2018most probable number\u2019","volume":"1","author":"Clarke, K.R.","unstructured":"Clarke, K.R. and Owens, N.J.P., 1983. A simple and versatile micro-computer program for the determination of \u2018most probable number\u2019. Journal of Microbiological Methods 1: 133-137. https:\/\/doi.org\/10.1016\/0167-7012(83)90031-3"},{"key":"R000008","author":"Clement, K.","unstructured":"Clement, K., LeRoy, T., Debadat, J. and Voland, L., 2022. Composition and use of Turicimonas muris for the treatment of metabolic diseases. PCT\/FR2022\/052482."},{"key":"R000009","series-title":"Food Research International","first-page":"109","article-title":"Qualification of tropical fruit-derived Lactobacillus plantarum strains as potential probiotics acting on blood glucose and total cholesterol levels in Wistar rats","volume":"124","author":"Da Costa, W.K.A.","unstructured":"Da Costa, W.K.A., Branda\u0303o, L.R., Martino, M.E., Garcia, E.F., Alves, A.F., de Souza, E.L., de Souza Aquino, J., Saarela, M., Leulier, F., Vidal, H. and Magnani, M., 2019. Qualification of tropical fruit-derived Lactobacillus plantarum strains as potential probiotics acting on blood glucose and total cholesterol levels in Wistar rats. Food Research International 124: 109-117. https:\/\/doi.org\/10.1016\/j.foodres.2018.08.035"},{"key":"R000010","series-title":"American Journal of Physiology \u2013 Endocrinology and Metabolism","first-page":"E279","article-title":"The role of FGF19 in metabolic regulation: insights from preclinical models to clinical trials","volume":"327","author":"de Carvalho, M.B.","unstructured":"de Carvalho, M.B., Jorge, G.M.C.P., Zanardo, L.W., Hamada, L.M., Izabel, L. dos S., Santoro, S. and Magdalon, J., 2024. The role of FGF19 in metabolic regulation: insights from preclinical models to clinical trials. American Journal of Physiology \u2013 Endocrinology and Metabolism 327: E279-E289. https:\/\/doi.org\/10.1152\/ajpendo.00156.2024"},{"key":"R000011","series-title":"Nature Medicine","first-page":"1096","article-title":"Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study","volume":"25","author":"Depommier, C.","unstructured":"Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N.M., de Barsy, M., Loumaye, A., Hermans, M.P., Thissen, J.-P., de Vos, W.M. and Cani, P.D., 2019. Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nature Medicine 25: 1096-1103. https:\/\/doi.org\/10.1038\/s41591-019-0495-2"},{"key":"R000012","series-title":"PLoS ONE","article-title":"Lactobacillus reuteri prevents diet-induced obesity, but not atherosclerosis, in a strain dependent fashion in Apoe\u2212\/\u2212 mice","volume":"7","author":"Fa\u030ak, F.","unstructured":"Fa\u030ak, F. and B\u00e4ckhed, F., 2012. Lactobacillus reuteri prevents diet-induced obesity, but not atherosclerosis, in a strain dependent fashion in Apoe\u2212\/\u2212 mice. PLoS ONE 7: e46837. https:\/\/doi.org\/10.1371\/journal.pone.0046837"},{"key":"R000013","series-title":"Frontiers in Microbiology","article-title":"Analysis of 1,000 type-strain genomes improves taxonomic classification of Bacteroidetes","volume":"10","author":"Garc\u0131\u0301a-Lo\u0301pez, M.","unstructured":"Garc\u0131\u0301a-Lo\u0301pez, M., Meier-Kolthoff, J.P., Tindall, B.J., Gronow, S., Woyke, T., Kyrpides, N.C., Hahnke, R.L. and G\u00f6ker, M., 2019. Analysis of 1,000 type-strain genomes improves taxonomic classification of Bacteroidetes. Frontiers in Microbiology 10: 2083. https:\/\/doi.org\/10.3389\/fmicb.2019.02083"},{"key":"R000014","series-title":"PLoS ONE","article-title":"Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity","volume":"7","author":"Gauffin Cano, P.","unstructured":"Gauffin Cano, P., Santacruz, A., Moya, A\u0301. and Sanz, Y., 2012. Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity. PLoS ONE 7: e41079. https:\/\/doi.org\/10.1371\/journal.pone.0041079"},{"key":"R000015","series-title":"Frontiers in Endocrinology","article-title":"Impact of gut microbiota on host glycemic control","volume":"10","author":"Ge\u0301rard, C.","unstructured":"Ge\u0301rard, C. and Vidal, H., 2019. Impact of gut microbiota on host glycemic control. Frontiers in Endocrinology 10: 29. https:\/\/doi.org\/10.3389\/fendo.2019.00029"},{"key":"R000016","series-title":"Applied and Environmental Microbiology","first-page":"5742","article-title":"Bacteroides sp. strain D8, the first cholesterol-reducing bacterium isolated from human feces","volume":"73","author":"Ge\u0301rard, P.","unstructured":"Ge\u0301rard, P., Lepercq, P., Leclerc, M., Gavini, F., Raibaud, P. and Juste, C., 2007. Bacteroides sp. strain D8, the first cholesterol-reducing bacterium isolated from human feces. Applied and Environmental Microbiology 73: 5742-5749. https:\/\/doi.org\/10.1128\/AEM.02806-06"},{"key":"R000017","unstructured":"Global status report on noncommunicable diseases, 2014. World Health Organization WHO\/NMH\/NVI\/15.1"},{"key":"R000018","series-title":"Molecular Metabolism","article-title":"Evaluation of the effects of metformin on gut functions and microbiota and their contribution to improving glucose tolerance in diabetic mice","volume":"102","author":"Godet, M.","unstructured":"Godet, M., Meugnier, E., Vitalis, O., Bendridi, N., Vieille-Marchiset, A., Vega, N., Benoit, B., Pinteur, C., Rainteau, D., Cheillan, D., Michalski, M.-C., Chikh, K. and Vidal, H., 2025. Evaluation of the effects of metformin on gut functions and microbiota and their contribution to improving glucose tolerance in diabetic mice. Molecular Metabolism 102: 102263. https:\/\/doi.org\/10.1016\/j.molmet.2025.102263"},{"key":"R000019","series-title":"Cellular and Molecular Life Sciences","article-title":"Contribution of specific ceramides to obesity-associated metabolic diseases","volume":"79","author":"Hammerschmidt, P.","unstructured":"Hammerschmidt, P. and Br\u00fcning, J.C., 2022. Contribution of specific ceramides to obesity-associated metabolic diseases. Cellular and Molecular Life Sciences 79: 395. https:\/\/doi.org\/10.1007\/s00018-022-04401-3"},{"key":"R000020","series-title":"Nutrition and Metabolism","article-title":"Oral administration of Lactobacillus reuteri GMNL-263 improves insulin resistance and ameliorates hepatic steatosis in high fructose-fed rats","volume":"10","author":"Hsieh, F.-C.","unstructured":"Hsieh, F.-C., Lee, C.-L., Chai, C.-Y., Chen, W.-T., Lu, Y.-C. and Wu, C.-S., 2013. Oral administration of Lactobacillus reuteri GMNL-263 improves insulin resistance and ameliorates hepatic steatosis in high fructose-fed rats. Nutrition and Metabolism 10: 35. https:\/\/doi.org\/10.1186\/1743-7075-10-35"},{"key":"R000021","series-title":"Journal of Chromatography B","first-page":"135","article-title":"Bile acid profiling in human biological samples: comparison of extraction procedures and application to normal and cholestatic patients","volume":"899","author":"Humbert, L.","unstructured":"Humbert, L., Maubert, M.A., Wolf, C., Duboc, H., Mahe\u0301, M., Farabos, D., Seksik, P., Mallet, J.M., Trugnan, G., Masliah, J. and Rainteau, D., 2012. Bile acid profiling in human biological samples: comparison of extraction procedures and application to normal and cholestatic patients. Journal of Chromatography B 899: 135-145. https:\/\/doi.org\/10.1016\/j.jchromb.2012.05.015"},{"key":"R000022","series-title":"Nature Communications","article-title":"Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction","volume":"6","author":"Jiang, C.","unstructured":"Jiang, C., Xie, C., Lv, Y., Li, J., Krausz, K.W., Shi, J., Brocker, C.N., Desai, D., Amin, S.G., Bisson, W.H., Liu, Y., Gavrilova, O., Patterson, A.D. and Gonzalez, F.J., 2015. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nature Communications 6: 10166. https:\/\/doi.org\/10.1038\/ncomms10166"},{"key":"R000023","series-title":"Nature Communications","article-title":"Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels","volume":"11","author":"Johnson, E.L.","unstructured":"Johnson, E.L., Heaver, S.L., Waters, J.L., Kim, B.I., Bretin, A., Goodman, A.L., Gewirtz, A.T., Worgall, T.S. and Ley, R.E., 2020. Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels. Nature Communications 11: 2471. https:\/\/doi.org\/10.1038\/s41467-020-16274-w"},{"key":"R000024","series-title":"Nature","first-page":"99","article-title":"Gut metagenome in European women with normal, impaired and diabetic glucose control","volume":"498","author":"Karlsson, F.H.","unstructured":"Karlsson, F.H., Tremaroli, V., Nookaew, I., Bergstr\u00f6m, G., Behre, C.J., Fagerberg, B., Nielsen, J. and B\u00e4ckhed, F., 2013. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 498: 99-103. https:\/\/doi.org\/10.1038\/nature12198"},{"key":"R000025","series-title":"BMC Gastroenterology","article-title":"Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing","volume":"15","author":"Kasai, C.","unstructured":"Kasai, C., Sugimoto, K., Moritani, I., Tanaka, J., Oya, Y., Inoue, H., Tameda, M., Shiraki, K., Ito, M., Takei, Y. and Takase, K., 2015. Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing. BMC Gastroenterology 15: 100. https:\/\/doi.org\/10.1186\/s12876-015-0330-2"},{"key":"R000026","series-title":"International Journal of Systematic and Evolutionary Microbiology","first-page":"1145","article-title":"Bacteroides stercorirosoris sp. nov. and Bacteroides faecichinchillae sp. nov., isolated from chinchilla (Chinchilla lanigera) faeces","volume":"62","author":"Kitahara, M.","unstructured":"Kitahara, M., Sakamoto, M., Tsuchida, S., Kawasumi, K., Amao, H., Benno, Y. and Ohkuma, M., 2012. Bacteroides stercorirosoris sp. nov. and Bacteroides faecichinchillae sp. nov., isolated from chinchilla (Chinchilla lanigera) faeces. International Journal of Systematic and Evolutionary Microbiology 62: 1145-1150. https:\/\/doi.org\/10.1099\/ijs.0.032706-0"},{"key":"R000027","series-title":"JCI Insight","article-title":"Milk polar lipids favorably alter circulating and intestinal ceramide and sphingomyelin species in postmenopausal women","volume":"6","author":"Le Barz, M.","unstructured":"Le Barz, M., Vors, C., Combe, E., Joumard-Cubizolles, L., Lecomte, M., Joffre, F., Trauchessec, M., Pesenti, S., Loizon, E., Breyton, A.-E., Meugnier, E., Bertrand, K., Drai, J., Robert, C., Durand, A., Cuerq, C., Gaborit, P., Leconte, N., Bernalier-Donadille, A., Cotte, E., Laville, M., Lambert-Porcheron, S., Ouchchane, L., Vidal, H., Malpuech-Bruge\u0300re, C., Cheillan, D. and Michalski, M.-C., 2021. Milk polar lipids favorably alter circulating and intestinal ceramide and sphingomyelin species in postmenopausal women. JCI Insight 6: e146161. https:\/\/doi.org\/10.1172\/jci.insight.146161"},{"key":"R000028","series-title":"Cell Host and Microbe","first-page":"798","article-title":"Host hepatic metabolism is modulated by gut microbiota\u2013derived sphingolipids","volume":"30","author":"Le, H.H.","unstructured":"Le, H.H., Lee, M.-T., Besler, K.R. and Johnson, E.L., 2022. Host hepatic metabolism is modulated by gut microbiota\u2013derived sphingolipids. Cell Host and Microbe 30: 798-808.e7. https:\/\/doi.org\/10.1016\/j.chom.2022.05.002"},{"key":"R000029","series-title":"Frontiers in Microbiology","article-title":"A novel bacterium, Butyricimonas virosa, preventing HFD-induced diabetes and metabolic disorders in mice via GLP-1 receptor","volume":"13","author":"Lee, H.","unstructured":"Lee, H., An, J., Kim, J., Choi, D., Song, Y., Lee, C.-K., Kong, H., Kim, S.B. and Kim, K., 2022. A novel bacterium, Butyricimonas virosa, preventing HFD-induced diabetes and metabolic disorders in mice via GLP-1 receptor. Frontiers in Microbiology 13: 858192. https:\/\/doi.org\/10.3389\/fmicb.2022.858192"},{"key":"R000030","series-title":"Nature","first-page":"1022","article-title":"Human gut microbes associated with obesity","volume":"444","author":"Ley, R.E.","unstructured":"Ley, R.E., Turnbaugh, P.J., Klein, S. and Gordon, J.I., 2006. Human gut microbes associated with obesity. Nature 444: 1022-1023. https:\/\/doi.org\/10.1038\/4441022a"},{"key":"R000031","series-title":"Frontiers in Nutrition","article-title":"Regulation of bile acids and their receptor FXR in metabolic diseases","volume":"11","author":"Li, Y.","unstructured":"Li, Y., Wang, L., Yi, Q., Luo, L. and Xiong, Y., 2024. Regulation of bile acids and their receptor FXR in metabolic diseases. Frontiers in Nutrition 11: 1447878. https:\/\/doi.org\/10.3389\/fnut.2024.1447878"},{"key":"R000032","series-title":"Cell Metabolism","first-page":"737","article-title":"Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome","volume":"28","author":"Natividad, J.M.","unstructured":"Natividad, J.M., Agus, A., Planchais, J., Lamas, B., Jarry, A.C., Martin, R., Michel, M.-L., Chong-Nguyen, C., Roussel, R., Straube, M., Jegou, S., McQuitty, C., Le Gall, M., Da Costa, G., Lecornet, E., Michaudel, C., Modoux, M., Glodt, J., Bridonneau, C., Sovran, B., Dupraz, L., Bado, A., Richard, M.L., Langella, P., Hansel, B., Launay, J.-M., Xavier, R.J., Duboc, H. and Sokol, H., 2018. Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome. Cell Metabolism 28: 737-749.e4. https:\/\/doi.org\/10.1016\/j.cmet.2018.07.001"},{"key":"R000033","series-title":"Nature Medicine","first-page":"107","article-title":"A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice","volume":"23","author":"Plovier, H.","unstructured":"Plovier, H., Everard, A., Druart, C., Depommier, C., Van Hul, M., Geurts, L., Chilloux, J., Ottman, N., Duparc, T., Lichtenstein, L., Myridakis, A., Delzenne, N.M., Klievink, J., Bhattacharjee, A., van\u00a0der Ark, K.C.H., Aalvink, S., Martinez, L.O., Dumas, M.-E., Maiter, D., Loumaye, A., Hermans, M.P., Thissen, J.-P., Belzer, C., de Vos, W.M. and Cani, P.D., 2017. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nature Medicine 23: 107-113. https:\/\/doi.org\/10.1038\/nm.4236"},{"key":"R000034","series-title":"Nature","first-page":"55","article-title":"A metagenome-wide association study of gut microbiota in type 2 diabetes","volume":"490","author":"Qin, J.","unstructured":"Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., Peng, Y., Zhang, D., Jie, Z., Wu, W., Qin, Y., Xue, W., Li, J., Han, L., Lu, D., Wu, P., Dai, Y., Sun, X., Li, Z., Tang, A., Zhong, S., Li, X., Chen, W., Xu, R., Wang, M., Feng, Q., Gong, M., Yu, J., Zhang, Y., Zhang, M., Hansen, T., Sanchez, G., Raes, J., Falony, G., Okuda, S., Almeida, M., LeChatelier, E., Renault, P., Pons, N., Batto, J.-M., Zhang, Z., Chen, H., Yang, R., Zheng, W., Li, S., Yang, H., Wang, J., Ehrlich, S.D., Nielsen, R., Pedersen, O., Kristiansen, K. and Wang, J., 2012. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490: 55-60. https:\/\/doi.org\/10.1038\/nature11450"},{"key":"R000035","series-title":"PLoS ONE","article-title":"Effect of probiotics on glycemic control: a systematic review and meta-analysis of randomized, controlled trials","volume":"10","author":"Ruan, Y.","unstructured":"Ruan, Y., Sun, J., He, J., Chen, F., Chen, R. and Chen, H., 2015. Effect of probiotics on glycemic control: a systematic review and meta-analysis of randomized, controlled trials. PLoS ONE 10: e0132121. https:\/\/doi.org\/10.1371\/journal.pone.0132121"},{"key":"R000036","series-title":"Gut","first-page":"727","article-title":"An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice","volume":"63","author":"Shin, N.-R.","unstructured":"Shin, N.-R., Lee, J.-C., Lee, H.-Y., Kim, M.-S., Whon, T.W., Lee, M.-S. and Bae, J.-W., 2014. An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice. Gut 63: 727-735. https:\/\/doi.org\/10.1136\/gutjnl-2012-303839"},{"key":"R000037","series-title":"Front. Endocrinol.","article-title":"The Role of Ceramides in Insulin Resistance","volume":"10","author":"Sokolowska, E.","unstructured":"Sokolowska, E. and Blachnio-Zabielska, A., 2019. The Role of Ceramides in Insulin Resistance. Front. Endocrinol. 10. https:\/\/doi.org\/10.3389\/fendo.2019.00577"},{"key":"R000038","series-title":"Nature Medicine","first-page":"1919","article-title":"Gut microbiota and intestinal FXR mediate the clinical benefits of metformin","volume":"24","author":"Sun, L.","unstructured":"Sun, L., Xie, C., Wang, G., Wu, Y., Wu, Q., Wang, X., Liu, J., Deng, Y., Xia, J., Chen, B., Zhang, S., Yun, C., Lian, G., Zhang, X., Zhang, H., Bisson, W.H., Shi, J., Gao, X., Ge, P., Liu, C., Krausz, K.W., Nichols, R.G., Cai, J., Rimal, B., Patterson, A.D., Wang, X., Gonzalez, F.J. and Jiang, C., 2018. Gut microbiota and intestinal FXR mediate the clinical benefits of metformin. Nature Medicine 24: 1919-1929. https:\/\/doi.org\/10.1038\/s41591-018-0222-4"},{"key":"R000039","series-title":"Food Research International","first-page":"637","article-title":"Investigations of Bacteroides spp. towards next-generation probiotics","volume":"116","author":"Tan, H.","unstructured":"Tan, H., Zhai, Q. and Chen, W., 2019. Investigations of Bacteroides spp. towards next-generation probiotics. Food Research International 116: 637-644. https:\/\/doi.org\/10.1016\/j.foodres.2018.08.088"},{"key":"R000040","series-title":"Cell Host Microbe","first-page":"213","article-title":"Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome","volume":"3","author":"Turnbaugh, P.J.","unstructured":"Turnbaugh, P.J., B\u00e4ckhed, F., Fulton, L. and Gordon, J.I., 2008. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3: 213-223. https:\/\/doi.org\/10.1016\/j.chom.2008.02.015"},{"key":"R000041","series-title":"Nature","first-page":"1027","article-title":"An obesity-associated gut microbiome with increased capacity for energy harvest","volume":"444","author":"Turnbaugh, P.J.","unstructured":"Turnbaugh, P.J., Ley, R.E., Mahowald, M.A., Magrini, V., Mardis, E.R. and Gordon, J.I., 2006. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444: 1027-1031. https:\/\/doi.org\/10.1038\/nature05414"},{"key":"R000042","series-title":"Nutrients","article-title":"Lactobacillus sakei ADM14 induces anti-obesity effects and changes in gut microbiome in high-fat diet-induced obese mice","volume":"12","author":"Won, S.-M.","unstructured":"Won, S.-M., Chen, S., Lee, S.Y., Lee, K.E., Park, K.W. and Yoon, J.-H., 2020. Lactobacillus sakei ADM14 induces anti-obesity effects and changes in gut microbiome in high-fat diet-induced obese mice. Nutrients 12: 3703. https:\/\/doi.org\/10.3390\/nu12123703"},{"key":"R000043","series-title":"Nutrition and Metabolism","article-title":"Animal models of metabolic syndrome: a review","volume":"13","author":"Wong, S.K.","unstructured":"Wong, S.K., Chin, K.-Y., Suhaimi, F.H., Fairus, A. and Ima-Nirwana, S., 2016. Animal models of metabolic syndrome: a review. Nutrition and Metabolism 13: 65. https:\/\/doi.org\/10.1186\/s12986-016-0123-9"},{"key":"R000044","series-title":"Nutrients","article-title":"Effects of long-term fasting on gut microbiota, serum metabolome, and their association in male adults","volume":"17","author":"Wu, F.","unstructured":"Wu, F., Guo, Y., Wang, Y., Sui, X., Wang, H., Zhang, H., Xin, B., Yang, C., Zhang, C., Jiang, S., Qu, L., Feng, Q., Dai, Z., Shi, C. and Li, Y., 2024. Effects of long-term fasting on gut microbiota, serum metabolome, and their association in male adults. Nutrients 17: 35. https:\/\/doi.org\/10.3390\/nu17010035"},{"key":"R000045","series-title":"Nature Medicine","first-page":"850","article-title":"Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug","volume":"23","author":"Wu, H.","unstructured":"Wu, H., Esteve, E., Tremaroli, V., Khan, M.T., Caesar, R., Mannera\u030as-Holm, L., Sta\u030ahlman, M., Olsson, L.M., Serino, M., Planas-Fe\u0300lix, M., Xifra, G., Mercader, J.M., Torrents, D., Burcelin, R., Ricart, W., Perkins, R., Ferna\u0300ndez-Real, J.M. and B\u00e4ckhed, F., 2017. Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. Nature Medicine 23: 850-858. https:\/\/doi.org\/10.1038\/nm.4345"},{"key":"R000046","series-title":"Diabetes","first-page":"613","article-title":"An intestinal farnesoid X receptor\u2013ceramide signaling axis modulates hepatic gluconeogenesis in mice","volume":"66","author":"Xie, C.","unstructured":"Xie, C., Jiang, C., Shi, J., Gao, X., Sun, D., Sun, L., Wang, T., Takahashi, S., Anitha, M., Krausz, K.W., Patterson, A.D. and Gonzalez, F.J., 2016. An intestinal farnesoid X receptor\u2013ceramide signaling axis modulates hepatic gluconeogenesis in mice. Diabetes 66: 613-626. https:\/\/doi.org\/10.2337\/db16-0663"},{"key":"R000047","series-title":"Applied Microbiology and Biotechnology","first-page":"6817","article-title":"Preventing non-alcoholic fatty liver disease through Lactobacillus johnsonii BS15 by attenuating inflammation and mitochondrial injury and improving gut environment in obese mice","volume":"98","author":"Xin, J.","unstructured":"Xin, J., Zeng, D., Wang, H., Ni, X., Yi, D., Pan, K. and Jing, B., 2014. Preventing non-alcoholic fatty liver disease through Lactobacillus johnsonii BS15 by attenuating inflammation and mitochondrial injury and improving gut environment in obese mice. Applied Microbiology and Biotechnology 98: 6817-6829. https:\/\/doi.org\/10.1007\/s00253-014-5752-1"},{"key":"R000048","series-title":"Biochemical and Biophysical Research Communications","article-title":"Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp","volume":"741","author":"Xu, X.","unstructured":"Xu, X., Wang, Y., Wu, X., Cai, T., Dong, L., Liang, S., Zhu, L., Song, X., Dong, Y., Zheng, Y., Li, L. and Sun, W., 2024. Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp. Biochemical and Biophysical Research Communications 741: 151033. https:\/\/doi.org\/10.1016\/j.bbrc.2024.151033"},{"key":"R000049","series-title":"Medical Science Monitor","first-page":"3044","article-title":"Effect of probiotics on glucose and lipid metabolism in type 2 diabetes mellitus: a meta-analysis of 12 randomized controlled trials","volume":"23","author":"Yao, K.","unstructured":"Yao, K., Zeng, L., He, Q., Wang, W., Lei, J. and Zou, X., 2017. Effect of probiotics on glucose and lipid metabolism in type 2 diabetes mellitus: a meta-analysis of 12 randomized controlled trials. Medical Science Monitor 23: 3044-3053. https:\/\/doi.org\/10.12659\/MSM.902600"},{"key":"R000050","series-title":"Frontiers in Microbiology","article-title":"Assessment of the safety and probiotic properties of Roseburia intestinalis: A potential \u2018Next Generation Probiotic\u2019","volume":"13","author":"Zhang, C.","unstructured":"Zhang, C., Ma, K., Nie, K., Deng, M., Luo, W., Wu, X., Huang, Y. and Wang, X., 2022. Assessment of the safety and probiotic properties of Roseburia intestinalis: A potential \u2018Next Generation Probiotic\u2019. Frontiers in Microbiology 13: 973046. https:\/\/doi.org\/10.3389\/fmicb.2022.973046"},{"key":"R000051","series-title":"Frontiers in Microbiology","article-title":"Bacteroides and NAFLD: pathophysiology and therapy","volume":"15","author":"Zhang, J.","unstructured":"Zhang, J., Zhou, J., He, Z. and Li, H., 2024. Bacteroides and NAFLD: pathophysiology and therapy. Frontiers in Microbiology 15: 1288856. https:\/\/doi.org\/10.3389\/fmicb.2024.1288856"},{"key":"R000052","series-title":"Microbiology Research","article-title":"Effects of intestinal Desulfovibrio bacteria on host health and its potential regulatory strategies: A review","volume":"284","author":"Zhou, H.","unstructured":"Zhou, H., Huang, D., Sun, Z. and Chen, X., 2024. Effects of intestinal Desulfovibrio bacteria on host health and its potential regulatory strategies: A review. Microbiology Research 284: 127725. https:\/\/doi.org\/10.1016\/j.micres.2024.127725"},{"key":"R000053","series-title":"Nutrients","article-title":"Exploration of the Muribaculaceae family in the gut microbiota: diversity, metabolism, and function","volume":"16","author":"Zhu, Y.","unstructured":"Zhu, Y., Chen, B., Zhang, X., Akbar, M.T., Wu, T., Zhang, Y., Zhi, L. and Shen, Q., 2024. Exploration of the Muribaculaceae family in the gut microbiota: diversity, metabolism, and function. Nutrients 16: 2660. https:\/\/doi.org\/10.3390\/nu16162660"},{"key":"R000001","series-title":"Molecular Biology Reports","article-title":"Next-generation probiotics: the upcoming biotherapeutics","volume":"51","author":"Al-Fakhrany, O.M.","unstructured":"Al-Fakhrany, O.M. and Elekhnawy, E., 2024. Next-generation probiotics: the upcoming biotherapeutics. Molecular Biology Reports 51: 505. https:\/\/doi.org\/10.1007\/s11033-024-09398-5"},{"key":"R000002","series-title":"Gut Microbes","article-title":"Inhibition of intestinal FXR activity as a possible mechanism for the beneficial effects of a probiotic mix supplementation on lipid metabolism alterations and weight gain in mice fed a high fat diet","volume":"15","author":"Beau, A.","unstructured":"Beau, A., Benoit, B., Le Barz, M., Meugnier, E., Penhoat, A., Calzada, C., Pinteur, C., Loizon, E., Chanon, S., Vieille-Marchiset, A., Sauvinet, V., Godet, M., Laugerette, F., Holowacz, S., Jacouton, E., Michalski, M.-C. and Vidal, H., 2023. Inhibition of intestinal FXR activity as a possible mechanism for the beneficial effects of a probiotic mix supplementation on lipid metabolism alterations and weight gain in mice fed a high fat diet. Gut Microbes 15: 2281015. https:\/\/doi.org\/10.1080\/19490976.2023.2281015"},{"key":"R000003","series-title":"Science Reports","article-title":"Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice","volume":"11","author":"Bravard, A.","unstructured":"Bravard, A., Ge\u0301rard, C., Defois, C., Benoit, B., Makki, K., Meugnier, E., Rainteau, D., Rieusset, J., Godet, M. and Vidal, H., 2021. Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice. Science Reports 11: 16684. https:\/\/doi.org\/10.1038\/s41598-021-95117-0"},{"key":"R000004","series-title":"Cell Host and Microbe","first-page":"668","article-title":"Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis","volume":"25","author":"Brown, E.M.","unstructured":"Brown, E.M., Ke, X., Hitchcock, D., Jeanfavre, S., Avila-Pacheco, J., Nakata, T., Arthur, T.D., Fornelos, N., Heim, C., Franzosa, E.A., Watson, N., Huttenhower, C., Haiser, H.J., Dillow, G., Graham, D.B., Finlay, B.B., Kostic, A.D., Porter, J.A., Vlamakis, H., Clish, C.B. and Xavier, R.J., 2019. Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis. Cell Host and Microbe 25: 668-680.e7. https:\/\/doi.org\/10.1016\/j.chom.2019.04.002"},{"key":"R000005","series-title":"Nature Reviews Endocrinology","first-page":"74","article-title":"The gut microbiota manages host metabolism","volume":"10","author":"Cani, P.D.","unstructured":"Cani, P.D., 2014. The gut microbiota manages host metabolism. Nature Reviews Endocrinology 10: 74-76. https:\/\/doi.org\/10.1038\/nrendo.2013.240"},{"key":"R000006","series-title":"Science Reports","article-title":"Gut commensal Kineothrix alysoides mitigates liver dysfunction by restoring lipid metabolism and gut microbial balance","volume":"13","author":"Choi, K.J.","unstructured":"Choi, K.J., Yoon, M.Y., Kim, J.-E. and Yoon, S.S., 2023. Gut commensal Kineothrix alysoides mitigates liver dysfunction by restoring lipid metabolism and gut microbial balance. Science Reports 13: 14668. https:\/\/doi.org\/10.1038\/s41598-023-41160-y"},{"key":"R000007","series-title":"Journal of Microbiological Methods","first-page":"133","article-title":"A simple and versatile micro-computer program for the determination of \u2018most probable number\u2019","volume":"1","author":"Clarke, K.R.","unstructured":"Clarke, K.R. and Owens, N.J.P., 1983. A simple and versatile micro-computer program for the determination of \u2018most probable number\u2019. Journal of Microbiological Methods 1: 133-137. https:\/\/doi.org\/10.1016\/0167-7012(83)90031-3"},{"key":"R000008","author":"Clement, K.","unstructured":"Clement, K., LeRoy, T., Debadat, J. and Voland, L., 2022. Composition and use of Turicimonas muris for the treatment of metabolic diseases. PCT\/FR2022\/052482."},{"key":"R000009","series-title":"Food Research International","first-page":"109","article-title":"Qualification of tropical fruit-derived Lactobacillus plantarum strains as potential probiotics acting on blood glucose and total cholesterol levels in Wistar rats","volume":"124","author":"Da Costa, W.K.A.","unstructured":"Da Costa, W.K.A., Branda\u0303o, L.R., Martino, M.E., Garcia, E.F., Alves, A.F., de Souza, E.L., de Souza Aquino, J., Saarela, M., Leulier, F., Vidal, H. and Magnani, M., 2019. Qualification of tropical fruit-derived Lactobacillus plantarum strains as potential probiotics acting on blood glucose and total cholesterol levels in Wistar rats. Food Research International 124: 109-117. https:\/\/doi.org\/10.1016\/j.foodres.2018.08.035"},{"key":"R000010","series-title":"American Journal of Physiology \u2013 Endocrinology and Metabolism","first-page":"E279","article-title":"The role of FGF19 in metabolic regulation: insights from preclinical models to clinical trials","volume":"327","author":"de Carvalho, M.B.","unstructured":"de Carvalho, M.B., Jorge, G.M.C.P., Zanardo, L.W., Hamada, L.M., Izabel, L. dos S., Santoro, S. and Magdalon, J., 2024. The role of FGF19 in metabolic regulation: insights from preclinical models to clinical trials. American Journal of Physiology \u2013 Endocrinology and Metabolism 327: E279-E289. https:\/\/doi.org\/10.1152\/ajpendo.00156.2024"},{"key":"R000011","series-title":"Nature Medicine","first-page":"1096","article-title":"Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study","volume":"25","author":"Depommier, C.","unstructured":"Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N.M., de Barsy, M., Loumaye, A., Hermans, M.P., Thissen, J.-P., de Vos, W.M. and Cani, P.D., 2019. Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nature Medicine 25: 1096-1103. https:\/\/doi.org\/10.1038\/s41591-019-0495-2"},{"key":"R000012","series-title":"PLoS ONE","article-title":"Lactobacillus reuteri prevents diet-induced obesity, but not atherosclerosis, in a strain dependent fashion in Apoe\u2212\/\u2212 mice","volume":"7","author":"Fa\u030ak, F.","unstructured":"Fa\u030ak, F. and B\u00e4ckhed, F., 2012. Lactobacillus reuteri prevents diet-induced obesity, but not atherosclerosis, in a strain dependent fashion in Apoe\u2212\/\u2212 mice. PLoS ONE 7: e46837. https:\/\/doi.org\/10.1371\/journal.pone.0046837"},{"key":"R000013","series-title":"Frontiers in Microbiology","article-title":"Analysis of 1,000 type-strain genomes improves taxonomic classification of Bacteroidetes","volume":"10","author":"Garc\u0131\u0301a-Lo\u0301pez, M.","unstructured":"Garc\u0131\u0301a-Lo\u0301pez, M., Meier-Kolthoff, J.P., Tindall, B.J., Gronow, S., Woyke, T., Kyrpides, N.C., Hahnke, R.L. and G\u00f6ker, M., 2019. Analysis of 1,000 type-strain genomes improves taxonomic classification of Bacteroidetes. Frontiers in Microbiology 10: 2083. https:\/\/doi.org\/10.3389\/fmicb.2019.02083"},{"key":"R000014","series-title":"PLoS ONE","article-title":"Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity","volume":"7","author":"Gauffin Cano, P.","unstructured":"Gauffin Cano, P., Santacruz, A., Moya, A\u0301. and Sanz, Y., 2012. Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity. PLoS ONE 7: e41079. https:\/\/doi.org\/10.1371\/journal.pone.0041079"},{"key":"R000015","series-title":"Frontiers in Endocrinology","article-title":"Impact of gut microbiota on host glycemic control","volume":"10","author":"Ge\u0301rard, C.","unstructured":"Ge\u0301rard, C. and Vidal, H., 2019. Impact of gut microbiota on host glycemic control. Frontiers in Endocrinology 10: 29. https:\/\/doi.org\/10.3389\/fendo.2019.00029"},{"key":"R000016","series-title":"Applied and Environmental Microbiology","first-page":"5742","article-title":"Bacteroides sp. strain D8, the first cholesterol-reducing bacterium isolated from human feces","volume":"73","author":"Ge\u0301rard, P.","unstructured":"Ge\u0301rard, P., Lepercq, P., Leclerc, M., Gavini, F., Raibaud, P. and Juste, C., 2007. Bacteroides sp. strain D8, the first cholesterol-reducing bacterium isolated from human feces. Applied and Environmental Microbiology 73: 5742-5749. https:\/\/doi.org\/10.1128\/AEM.02806-06"},{"key":"R000017","unstructured":"Global status report on noncommunicable diseases, 2014. World Health Organization WHO\/NMH\/NVI\/15.1"},{"key":"R000018","series-title":"Molecular Metabolism","article-title":"Evaluation of the effects of metformin on gut functions and microbiota and their contribution to improving glucose tolerance in diabetic mice","volume":"102","author":"Godet, M.","unstructured":"Godet, M., Meugnier, E., Vitalis, O., Bendridi, N., Vieille-Marchiset, A., Vega, N., Benoit, B., Pinteur, C., Rainteau, D., Cheillan, D., Michalski, M.-C., Chikh, K. and Vidal, H., 2025. Evaluation of the effects of metformin on gut functions and microbiota and their contribution to improving glucose tolerance in diabetic mice. Molecular Metabolism 102: 102263. https:\/\/doi.org\/10.1016\/j.molmet.2025.102263"},{"key":"R000019","series-title":"Cellular and Molecular Life Sciences","article-title":"Contribution of specific ceramides to obesity-associated metabolic diseases","volume":"79","author":"Hammerschmidt, P.","unstructured":"Hammerschmidt, P. and Br\u00fcning, J.C., 2022. Contribution of specific ceramides to obesity-associated metabolic diseases. Cellular and Molecular Life Sciences 79: 395. https:\/\/doi.org\/10.1007\/s00018-022-04401-3"},{"key":"R000020","series-title":"Nutrition and Metabolism","article-title":"Oral administration of Lactobacillus reuteri GMNL-263 improves insulin resistance and ameliorates hepatic steatosis in high fructose-fed rats","volume":"10","author":"Hsieh, F.-C.","unstructured":"Hsieh, F.-C., Lee, C.-L., Chai, C.-Y., Chen, W.-T., Lu, Y.-C. and Wu, C.-S., 2013. Oral administration of Lactobacillus reuteri GMNL-263 improves insulin resistance and ameliorates hepatic steatosis in high fructose-fed rats. Nutrition and Metabolism 10: 35. https:\/\/doi.org\/10.1186\/1743-7075-10-35"},{"key":"R000021","series-title":"Journal of Chromatography B","first-page":"135","article-title":"Bile acid profiling in human biological samples: comparison of extraction procedures and application to normal and cholestatic patients","volume":"899","author":"Humbert, L.","unstructured":"Humbert, L., Maubert, M.A., Wolf, C., Duboc, H., Mahe\u0301, M., Farabos, D., Seksik, P., Mallet, J.M., Trugnan, G., Masliah, J. and Rainteau, D., 2012. Bile acid profiling in human biological samples: comparison of extraction procedures and application to normal and cholestatic patients. Journal of Chromatography B 899: 135-145. https:\/\/doi.org\/10.1016\/j.jchromb.2012.05.015"},{"key":"R000022","series-title":"Nature Communications","article-title":"Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction","volume":"6","author":"Jiang, C.","unstructured":"Jiang, C., Xie, C., Lv, Y., Li, J., Krausz, K.W., Shi, J., Brocker, C.N., Desai, D., Amin, S.G., Bisson, W.H., Liu, Y., Gavrilova, O., Patterson, A.D. and Gonzalez, F.J., 2015. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nature Communications 6: 10166. https:\/\/doi.org\/10.1038\/ncomms10166"},{"key":"R000023","series-title":"Nature Communications","article-title":"Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels","volume":"11","author":"Johnson, E.L.","unstructured":"Johnson, E.L., Heaver, S.L., Waters, J.L., Kim, B.I., Bretin, A., Goodman, A.L., Gewirtz, A.T., Worgall, T.S. and Ley, R.E., 2020. Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels. Nature Communications 11: 2471. https:\/\/doi.org\/10.1038\/s41467-020-16274-w"},{"key":"R000024","series-title":"Nature","first-page":"99","article-title":"Gut metagenome in European women with normal, impaired and diabetic glucose control","volume":"498","author":"Karlsson, F.H.","unstructured":"Karlsson, F.H., Tremaroli, V., Nookaew, I., Bergstr\u00f6m, G., Behre, C.J., Fagerberg, B., Nielsen, J. and B\u00e4ckhed, F., 2013. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 498: 99-103. https:\/\/doi.org\/10.1038\/nature12198"},{"key":"R000025","series-title":"BMC Gastroenterology","article-title":"Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing","volume":"15","author":"Kasai, C.","unstructured":"Kasai, C., Sugimoto, K., Moritani, I., Tanaka, J., Oya, Y., Inoue, H., Tameda, M., Shiraki, K., Ito, M., Takei, Y. and Takase, K., 2015. Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing. BMC Gastroenterology 15: 100. https:\/\/doi.org\/10.1186\/s12876-015-0330-2"},{"key":"R000026","series-title":"International Journal of Systematic and Evolutionary Microbiology","first-page":"1145","article-title":"Bacteroides stercorirosoris sp. nov. and Bacteroides faecichinchillae sp. nov., isolated from chinchilla (Chinchilla lanigera) faeces","volume":"62","author":"Kitahara, M.","unstructured":"Kitahara, M., Sakamoto, M., Tsuchida, S., Kawasumi, K., Amao, H., Benno, Y. and Ohkuma, M., 2012. Bacteroides stercorirosoris sp. nov. and Bacteroides faecichinchillae sp. nov., isolated from chinchilla (Chinchilla lanigera) faeces. International Journal of Systematic and Evolutionary Microbiology 62: 1145-1150. https:\/\/doi.org\/10.1099\/ijs.0.032706-0"},{"key":"R000027","series-title":"JCI Insight","article-title":"Milk polar lipids favorably alter circulating and intestinal ceramide and sphingomyelin species in postmenopausal women","volume":"6","author":"Le Barz, M.","unstructured":"Le Barz, M., Vors, C., Combe, E., Joumard-Cubizolles, L., Lecomte, M., Joffre, F., Trauchessec, M., Pesenti, S., Loizon, E., Breyton, A.-E., Meugnier, E., Bertrand, K., Drai, J., Robert, C., Durand, A., Cuerq, C., Gaborit, P., Leconte, N., Bernalier-Donadille, A., Cotte, E., Laville, M., Lambert-Porcheron, S., Ouchchane, L., Vidal, H., Malpuech-Bruge\u0300re, C., Cheillan, D. and Michalski, M.-C., 2021. Milk polar lipids favorably alter circulating and intestinal ceramide and sphingomyelin species in postmenopausal women. JCI Insight 6: e146161. https:\/\/doi.org\/10.1172\/jci.insight.146161"},{"key":"R000028","series-title":"Cell Host and Microbe","first-page":"798","article-title":"Host hepatic metabolism is modulated by gut microbiota\u2013derived sphingolipids","volume":"30","author":"Le, H.H.","unstructured":"Le, H.H., Lee, M.-T., Besler, K.R. and Johnson, E.L., 2022. Host hepatic metabolism is modulated by gut microbiota\u2013derived sphingolipids. Cell Host and Microbe 30: 798-808.e7. https:\/\/doi.org\/10.1016\/j.chom.2022.05.002"},{"key":"R000029","series-title":"Frontiers in Microbiology","article-title":"A novel bacterium, Butyricimonas virosa, preventing HFD-induced diabetes and metabolic disorders in mice via GLP-1 receptor","volume":"13","author":"Lee, H.","unstructured":"Lee, H., An, J., Kim, J., Choi, D., Song, Y., Lee, C.-K., Kong, H., Kim, S.B. and Kim, K., 2022. A novel bacterium, Butyricimonas virosa, preventing HFD-induced diabetes and metabolic disorders in mice via GLP-1 receptor. Frontiers in Microbiology 13: 858192. https:\/\/doi.org\/10.3389\/fmicb.2022.858192"},{"key":"R000030","series-title":"Nature","first-page":"1022","article-title":"Human gut microbes associated with obesity","volume":"444","author":"Ley, R.E.","unstructured":"Ley, R.E., Turnbaugh, P.J., Klein, S. and Gordon, J.I., 2006. Human gut microbes associated with obesity. Nature 444: 1022-1023. https:\/\/doi.org\/10.1038\/4441022a"},{"key":"R000031","series-title":"Frontiers in Nutrition","article-title":"Regulation of bile acids and their receptor FXR in metabolic diseases","volume":"11","author":"Li, Y.","unstructured":"Li, Y., Wang, L., Yi, Q., Luo, L. and Xiong, Y., 2024. Regulation of bile acids and their receptor FXR in metabolic diseases. Frontiers in Nutrition 11: 1447878. https:\/\/doi.org\/10.3389\/fnut.2024.1447878"},{"key":"R000032","series-title":"Cell Metabolism","first-page":"737","article-title":"Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome","volume":"28","author":"Natividad, J.M.","unstructured":"Natividad, J.M., Agus, A., Planchais, J., Lamas, B., Jarry, A.C., Martin, R., Michel, M.-L., Chong-Nguyen, C., Roussel, R., Straube, M., Jegou, S., McQuitty, C., Le Gall, M., Da Costa, G., Lecornet, E., Michaudel, C., Modoux, M., Glodt, J., Bridonneau, C., Sovran, B., Dupraz, L., Bado, A., Richard, M.L., Langella, P., Hansel, B., Launay, J.-M., Xavier, R.J., Duboc, H. and Sokol, H., 2018. Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome. Cell Metabolism 28: 737-749.e4. https:\/\/doi.org\/10.1016\/j.cmet.2018.07.001"},{"key":"R000033","series-title":"Nature Medicine","first-page":"107","article-title":"A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice","volume":"23","author":"Plovier, H.","unstructured":"Plovier, H., Everard, A., Druart, C., Depommier, C., Van Hul, M., Geurts, L., Chilloux, J., Ottman, N., Duparc, T., Lichtenstein, L., Myridakis, A., Delzenne, N.M., Klievink, J., Bhattacharjee, A., van\u00a0der Ark, K.C.H., Aalvink, S., Martinez, L.O., Dumas, M.-E., Maiter, D., Loumaye, A., Hermans, M.P., Thissen, J.-P., Belzer, C., de Vos, W.M. and Cani, P.D., 2017. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nature Medicine 23: 107-113. https:\/\/doi.org\/10.1038\/nm.4236"},{"key":"R000034","series-title":"Nature","first-page":"55","article-title":"A metagenome-wide association study of gut microbiota in type 2 diabetes","volume":"490","author":"Qin, J.","unstructured":"Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., Peng, Y., Zhang, D., Jie, Z., Wu, W., Qin, Y., Xue, W., Li, J., Han, L., Lu, D., Wu, P., Dai, Y., Sun, X., Li, Z., Tang, A., Zhong, S., Li, X., Chen, W., Xu, R., Wang, M., Feng, Q., Gong, M., Yu, J., Zhang, Y., Zhang, M., Hansen, T., Sanchez, G., Raes, J., Falony, G., Okuda, S., Almeida, M., LeChatelier, E., Renault, P., Pons, N., Batto, J.-M., Zhang, Z., Chen, H., Yang, R., Zheng, W., Li, S., Yang, H., Wang, J., Ehrlich, S.D., Nielsen, R., Pedersen, O., Kristiansen, K. and Wang, J., 2012. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490: 55-60. https:\/\/doi.org\/10.1038\/nature11450"},{"key":"R000035","series-title":"PLoS ONE","article-title":"Effect of probiotics on glycemic control: a systematic review and meta-analysis of randomized, controlled trials","volume":"10","author":"Ruan, Y.","unstructured":"Ruan, Y., Sun, J., He, J., Chen, F., Chen, R. and Chen, H., 2015. Effect of probiotics on glycemic control: a systematic review and meta-analysis of randomized, controlled trials. PLoS ONE 10: e0132121. https:\/\/doi.org\/10.1371\/journal.pone.0132121"},{"key":"R000036","series-title":"Gut","first-page":"727","article-title":"An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice","volume":"63","author":"Shin, N.-R.","unstructured":"Shin, N.-R., Lee, J.-C., Lee, H.-Y., Kim, M.-S., Whon, T.W., Lee, M.-S. and Bae, J.-W., 2014. An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice. Gut 63: 727-735. https:\/\/doi.org\/10.1136\/gutjnl-2012-303839"},{"key":"R000037","series-title":"Front. Endocrinol.","article-title":"The Role of Ceramides in Insulin Resistance","volume":"10","author":"Sokolowska, E.","unstructured":"Sokolowska, E. and Blachnio-Zabielska, A., 2019. The Role of Ceramides in Insulin Resistance. Front. Endocrinol. 10. https:\/\/doi.org\/10.3389\/fendo.2019.00577"},{"key":"R000038","series-title":"Nature Medicine","first-page":"1919","article-title":"Gut microbiota and intestinal FXR mediate the clinical benefits of metformin","volume":"24","author":"Sun, L.","unstructured":"Sun, L., Xie, C., Wang, G., Wu, Y., Wu, Q., Wang, X., Liu, J., Deng, Y., Xia, J., Chen, B., Zhang, S., Yun, C., Lian, G., Zhang, X., Zhang, H., Bisson, W.H., Shi, J., Gao, X., Ge, P., Liu, C., Krausz, K.W., Nichols, R.G., Cai, J., Rimal, B., Patterson, A.D., Wang, X., Gonzalez, F.J. and Jiang, C., 2018. Gut microbiota and intestinal FXR mediate the clinical benefits of metformin. Nature Medicine 24: 1919-1929. https:\/\/doi.org\/10.1038\/s41591-018-0222-4"},{"key":"R000039","series-title":"Food Research International","first-page":"637","article-title":"Investigations of Bacteroides spp. towards next-generation probiotics","volume":"116","author":"Tan, H.","unstructured":"Tan, H., Zhai, Q. and Chen, W., 2019. Investigations of Bacteroides spp. towards next-generation probiotics. Food Research International 116: 637-644. https:\/\/doi.org\/10.1016\/j.foodres.2018.08.088"},{"key":"R000040","series-title":"Cell Host Microbe","first-page":"213","article-title":"Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome","volume":"3","author":"Turnbaugh, P.J.","unstructured":"Turnbaugh, P.J., B\u00e4ckhed, F., Fulton, L. and Gordon, J.I., 2008. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3: 213-223. https:\/\/doi.org\/10.1016\/j.chom.2008.02.015"},{"key":"R000041","series-title":"Nature","first-page":"1027","article-title":"An obesity-associated gut microbiome with increased capacity for energy harvest","volume":"444","author":"Turnbaugh, P.J.","unstructured":"Turnbaugh, P.J., Ley, R.E., Mahowald, M.A., Magrini, V., Mardis, E.R. and Gordon, J.I., 2006. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444: 1027-1031. https:\/\/doi.org\/10.1038\/nature05414"},{"key":"R000042","series-title":"Nutrients","article-title":"Lactobacillus sakei ADM14 induces anti-obesity effects and changes in gut microbiome in high-fat diet-induced obese mice","volume":"12","author":"Won, S.-M.","unstructured":"Won, S.-M., Chen, S., Lee, S.Y., Lee, K.E., Park, K.W. and Yoon, J.-H., 2020. Lactobacillus sakei ADM14 induces anti-obesity effects and changes in gut microbiome in high-fat diet-induced obese mice. Nutrients 12: 3703. https:\/\/doi.org\/10.3390\/nu12123703"},{"key":"R000043","series-title":"Nutrition and Metabolism","article-title":"Animal models of metabolic syndrome: a review","volume":"13","author":"Wong, S.K.","unstructured":"Wong, S.K., Chin, K.-Y., Suhaimi, F.H., Fairus, A. and Ima-Nirwana, S., 2016. Animal models of metabolic syndrome: a review. Nutrition and Metabolism 13: 65. https:\/\/doi.org\/10.1186\/s12986-016-0123-9"},{"key":"R000044","series-title":"Nutrients","article-title":"Effects of long-term fasting on gut microbiota, serum metabolome, and their association in male adults","volume":"17","author":"Wu, F.","unstructured":"Wu, F., Guo, Y., Wang, Y., Sui, X., Wang, H., Zhang, H., Xin, B., Yang, C., Zhang, C., Jiang, S., Qu, L., Feng, Q., Dai, Z., Shi, C. and Li, Y., 2024. Effects of long-term fasting on gut microbiota, serum metabolome, and their association in male adults. Nutrients 17: 35. https:\/\/doi.org\/10.3390\/nu17010035"},{"key":"R000045","series-title":"Nature Medicine","first-page":"850","article-title":"Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug","volume":"23","author":"Wu, H.","unstructured":"Wu, H., Esteve, E., Tremaroli, V., Khan, M.T., Caesar, R., Mannera\u030as-Holm, L., Sta\u030ahlman, M., Olsson, L.M., Serino, M., Planas-Fe\u0300lix, M., Xifra, G., Mercader, J.M., Torrents, D., Burcelin, R., Ricart, W., Perkins, R., Ferna\u0300ndez-Real, J.M. and B\u00e4ckhed, F., 2017. Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. Nature Medicine 23: 850-858. https:\/\/doi.org\/10.1038\/nm.4345"},{"key":"R000046","series-title":"Diabetes","first-page":"613","article-title":"An intestinal farnesoid X receptor\u2013ceramide signaling axis modulates hepatic gluconeogenesis in mice","volume":"66","author":"Xie, C.","unstructured":"Xie, C., Jiang, C., Shi, J., Gao, X., Sun, D., Sun, L., Wang, T., Takahashi, S., Anitha, M., Krausz, K.W., Patterson, A.D. and Gonzalez, F.J., 2016. An intestinal farnesoid X receptor\u2013ceramide signaling axis modulates hepatic gluconeogenesis in mice. Diabetes 66: 613-626. https:\/\/doi.org\/10.2337\/db16-0663"},{"key":"R000047","series-title":"Applied Microbiology and Biotechnology","first-page":"6817","article-title":"Preventing non-alcoholic fatty liver disease through Lactobacillus johnsonii BS15 by attenuating inflammation and mitochondrial injury and improving gut environment in obese mice","volume":"98","author":"Xin, J.","unstructured":"Xin, J., Zeng, D., Wang, H., Ni, X., Yi, D., Pan, K. and Jing, B., 2014. Preventing non-alcoholic fatty liver disease through Lactobacillus johnsonii BS15 by attenuating inflammation and mitochondrial injury and improving gut environment in obese mice. Applied Microbiology and Biotechnology 98: 6817-6829. https:\/\/doi.org\/10.1007\/s00253-014-5752-1"},{"key":"R000048","series-title":"Biochemical and Biophysical Research Communications","article-title":"Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp","volume":"741","author":"Xu, X.","unstructured":"Xu, X., Wang, Y., Wu, X., Cai, T., Dong, L., Liang, S., Zhu, L., Song, X., Dong, Y., Zheng, Y., Li, L. and Sun, W., 2024. Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp. Biochemical and Biophysical Research Communications 741: 151033. https:\/\/doi.org\/10.1016\/j.bbrc.2024.151033"},{"key":"R000049","series-title":"Medical Science Monitor","first-page":"3044","article-title":"Effect of probiotics on glucose and lipid metabolism in type 2 diabetes mellitus: a meta-analysis of 12 randomized controlled trials","volume":"23","author":"Yao, K.","unstructured":"Yao, K., Zeng, L., He, Q., Wang, W., Lei, J. and Zou, X., 2017. Effect of probiotics on glucose and lipid metabolism in type 2 diabetes mellitus: a meta-analysis of 12 randomized controlled trials. Medical Science Monitor 23: 3044-3053. https:\/\/doi.org\/10.12659\/MSM.902600"},{"key":"R000050","series-title":"Frontiers in Microbiology","article-title":"Assessment of the safety and probiotic properties of Roseburia intestinalis: A potential \u2018Next Generation Probiotic\u2019","volume":"13","author":"Zhang, C.","unstructured":"Zhang, C., Ma, K., Nie, K., Deng, M., Luo, W., Wu, X., Huang, Y. and Wang, X., 2022. Assessment of the safety and probiotic properties of Roseburia intestinalis: A potential \u2018Next Generation Probiotic\u2019. Frontiers in Microbiology 13: 973046. https:\/\/doi.org\/10.3389\/fmicb.2022.973046"},{"key":"R000051","series-title":"Frontiers in Microbiology","article-title":"Bacteroides and NAFLD: pathophysiology and therapy","volume":"15","author":"Zhang, J.","unstructured":"Zhang, J., Zhou, J., He, Z. and Li, H., 2024. Bacteroides and NAFLD: pathophysiology and therapy. Frontiers in Microbiology 15: 1288856. https:\/\/doi.org\/10.3389\/fmicb.2024.1288856"},{"key":"R000052","series-title":"Microbiology Research","article-title":"Effects of intestinal Desulfovibrio bacteria on host health and its potential regulatory strategies: A review","volume":"284","author":"Zhou, H.","unstructured":"Zhou, H., Huang, D., Sun, Z. and Chen, X., 2024. Effects of intestinal Desulfovibrio bacteria on host health and its potential regulatory strategies: A review. Microbiology Research 284: 127725. https:\/\/doi.org\/10.1016\/j.micres.2024.127725"},{"key":"R000053","series-title":"Nutrients","article-title":"Exploration of the Muribaculaceae family in the gut microbiota: diversity, metabolism, and function","volume":"16","author":"Zhu, Y.","unstructured":"Zhu, Y., Chen, B., Zhang, X., Akbar, M.T., Wu, T., Zhang, Y., Zhi, L. and Shen, Q., 2024. Exploration of the Muribaculaceae family in the gut microbiota: diversity, metabolism, and function. Nutrients 16: 2660. https:\/\/doi.org\/10.3390\/nu16162660"}],"container-title":["Beneficial Microbes"],"original-title":[],"link":[{"URL":"https:\/\/brill.com\/view\/journals\/bm\/aop\/article-10.1163-18762891-bja00118\/article-10.1163-18762891-bja00118.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/brill.com\/downloadpdf\/journals\/bm\/aop\/article-10.1163-18762891-bja00118\/article-10.1163-18762891-bja00118.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/brill.com\/downloadpdf\/journals\/bm\/aop\/article-10.1163-18762891-bja00118\/article-10.1163-18762891-bja00118.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:06:49Z","timestamp":1778728009000},"score":1,"resource":{"primary":{"URL":"https:\/\/brill.com\/view\/journals\/bm\/aop\/article-10.1163-18762891-bja00118\/article-10.1163-18762891-bja00118.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,12]]},"references-count":106,"URL":"https:\/\/doi.org\/10.1163\/18762891-bja00118","relation":{},"ISSN":["1876-2891"],"issn-type":[{"value":"1876-2891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,12]]}}}