{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:14:26Z","timestamp":1778728466588,"version":"3.51.4"},"reference-count":114,"publisher":"Walter de Gruyter GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Benef. Microbes"],"published-print":{"date-parts":[[2026,5,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    A large fraction of the intestinal microbiota is highly coated with secretory IgA, and bacteria-specific IgA is believed to shape the composition of the microbiota. A hallmark of the adaptive immune system is immunological memory to specific antigens. However, whether there is strong and persistent memory of secretory antibodies to bacterial antigens has not been determined. Here we show that ultra long-lived CD19\n                    <jats:sup>\u2013<\/jats:sup>\n                    CD45\n                    <jats:sup>\u2013<\/jats:sup>\n                    (age &gt; 20 years) plasma cells (PCs) residing in the human small intestine produce IgA that binds to most taxa of a diverse anaerobic microbiota culture. Long-lived CD19\n                    <jats:sup>\u2013<\/jats:sup>\n                    CD45\n                    <jats:sup>+<\/jats:sup>\n                    (age &gt; 10 years) and short-lived CD19\n                    <jats:sup>+<\/jats:sup>\n                    CD45\n                    <jats:sup>+<\/jats:sup>\n                    (age &lt; 2 years) PCs also produced IgA with broad bacterial reactivity. A clear correlation between high-binding and low-binding taxa was observed across the PC subsets. We also found that host PCs were depleted in acute intestinal graft versus host disease, a condition strongly associated with loss of microbiota diversity. Together, we show that bacterial antigens in the intestine induce an extremely stable, long-lasting humoral immune memory that may be important for the long-term stability and resilience of the intestinal microbiome.\n                  <\/jats:p>","DOI":"10.1163\/18762891-bja00120","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:05:07Z","timestamp":1778727907000},"page":"1-13","source":"Crossref","is-referenced-by-count":0,"title":["Ultra long-lived plasma cells in the human small intestine produce microbiota-reactive IgA antibodies"],"prefix":"10.1163","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2902-8918","authenticated-orcid":true,"given":"N.B.","family":"Pati","sequence":"first","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Department of Pathology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"},{"name":"Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.K.","family":"Chung","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Norwegian PSC Research Center and Research Institute of Internal medicine, Division of Surgery, Inflammatory diseases and Transplantation, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Holm","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Norwegian PSC Research Center and Research Institute of Internal medicine, Division of Surgery, Inflammatory diseases and Transplantation, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"S\u00e6tre","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Department of Pathology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.M.","family":"Reims","sequence":"additional","affiliation":[{"name":"Department of Pathology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.T.","family":"Aasebo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Gedde-Dahl","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Department of Hematology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.V.","family":"Sreelakshmi","sequence":"additional","affiliation":[{"name":"Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Domanska","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Department of Pathology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.R.","family":"Hov","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Norwegian PSC Research Center and Research Institute of Internal medicine, Division of Surgery, Inflammatory diseases and Transplantation, Oslo University Hospital, Oslo, Norway"},{"name":"Section of Gatroenterology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.S.","family":"B\u00e6kkevold","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Department of Pathology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.L.","family":"Jahnsen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, https:\/\/dx.doi.org\/6305University of Oslo, Oslo, Norway"},{"name":"Department of Pathology, Oslo University Hospital-Rikshospitalet, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"R000001","series-title":"Transplant Cellular Therapy","first-page":"e1","article-title":"Calprotectin expressing donor-derived macrophages increase in acute gastrointestinal graft-versus-host disease","volume":"28","author":"Aasebo, A.T.","unstructured":"Aasebo, A.T., Gedde-Dahl, T., Reims, H.M., Baekkevold, E.S. and Jahnsen, F.L., 2022. Calprotectin expressing donor-derived macrophages increase in acute gastrointestinal graft-versus-host disease. Transplant Cellular Therapy 28: e1-248."},{"key":"R000002","series-title":"PeerJ","article-title":"Compact graphical representation of phylogenetic data and metadata with GraPhlAn","volume":"3","author":"Asnicar, F.","unstructured":"Asnicar, F., Weingart, G., Tickle, T.L., Huttenhower, C. and Segata, N., 2015. Compact graphical representation of phylogenetic data and metadata with GraPhlAn. PeerJ 3: e1029."},{"key":"R000003","series-title":"Mucosal Immunology","first-page":"402","article-title":"CD4(+) T cells persist for years in the human small intestine and display a T(H)1 cytokine profile","volume":"14","author":"Bartolome\u0301-Casado, R.","unstructured":"Bartolome\u0301-Casado, R., Landsverk, O.J.B., Chauhan, S.K., S\u00e6tre, F., Hagen, K.T., Yaqub, S., \u00d8yen, O., Horneland, R., Aandahl, E.M., Aabakken, L., B\u00e6kkevold, E.S. and Jahnsen, F.L., 2021. CD4(+) T cells persist for years in the human small intestine and display a T(H)1 cytokine profile. Mucosal Immunology 14: 402-410."},{"key":"R000004","series-title":"Best Practice and Research Clinical Gastroenterology","article-title":"Therapeutic potential of an anaerobic cultured human intestinal microbiota, ACHIM, for treatment of IBS","volume":"40-41","author":"Benno, P.","unstructured":"Benno, P., Norin, E., Midtvedt, T. and Hellstr\u00f6m, P.M., 2019. Therapeutic potential of an anaerobic cultured human intestinal microbiota, ACHIM, for treatment of IBS. Best Practice and Research Clinical Gastroenterology 40-41: 101607."},{"key":"R000005","series-title":"Immunological Reviews","first-page":"32","article-title":"Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties","volume":"206","author":"Brandtzaeg, P.","unstructured":"Brandtzaeg, P. and Johansen, F.E., 2005. Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties. Immunological Reviews 206: 32-63."},{"key":"R000006","series-title":"Immunity","first-page":"211","article-title":"IgA Responses to Microbiota","volume":"49","author":"Bunker, J.J.","unstructured":"Bunker, J.J. and Bendelac, A., 2018. IgA Responses to Microbiota. Immunity 49: 211-224."},{"key":"R000007","series-title":"Science","article-title":"Natural polyreactive IgA antibodies coat the intestinal microbiota","volume":"358","author":"Bunker, J.J.","unstructured":"Bunker, J.J., Erickson, S.A., Flynn, T.M., Henry, C., Koval, J.C., Meisel, M., Jabri, B., Antonopoulos, D.A., Wilson, P.C. and Bendelac, A., 2017. Natural polyreactive IgA antibodies coat the intestinal microbiota. Science 358: eaan6619."},{"key":"R000008","series-title":"Scientific Reports","article-title":"IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM","volume":"9","author":"Catanzaro, J.R.","unstructured":"Catanzaro, J.R., Strauss, J.D., Bielecka, A., Porto, A.F., Lobo, F.M., Urban, A., Schofield, W.B. and Palm, N.W., 2019. IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM. Scientific Reports 9: 13574."},{"key":"R000009","series-title":"Nature","first-page":"421","article-title":"BCR selection and affinity maturation in Peyer\u2019s patch germinal centres","volume":"582","author":"Chen, H.","unstructured":"Chen, H., Zhang, Y., Ye, A.Y., Du, Z., Xu, M., Lee, C.S., Hwang, J.K., Kyritsis, N., Ba, Z., Neuberg, D., Littman, D.R. and Alt, F.W., 2020. BCR selection and affinity maturation in Peyer\u2019s patch germinal centres. Nature 582: 421-425."},{"key":"R000010","series-title":"Journal of Clinical Investigation","first-page":"4624","article-title":"Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease","volume":"130","author":"Divito, S.J.","unstructured":"Divito, S.J., Aaseb\u00f8, A.T., Matos, T.R., Hsieh, P.C., Collin, M., Elco, C.P., O\u2019Malley, J.T., B\u00e6kkevold, E.S., Reims, H., Gedde-Dahl, T., Hagerstrom, M., Hilaire, J., Lian, J.W., Milford, E.L., Pinkus, G.S., Ho, V.T., Soiffer, R.J., Kim, H.T., Mihm, M.C., Ritz, J., Guleria, I., Cutler, C.S., Clark, R.A., Jahnsen, F.L. and Kupper, T.S., 2020. Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease. Journal of Clinical Investigation 130: 4624-4636."},{"key":"R000011","series-title":"Journal of Experimental Medicine","first-page":"20","article-title":"The gut microbiome: Relationships with disease and opportunities for therapy","volume":"216","author":"Durack, J.","unstructured":"Durack, J. and Lynch, S.V., 2019. The gut microbiome: Relationships with disease and opportunities for therapy. Journal of Experimental Medicine 216: 20-40."},{"key":"R000012","series-title":"Journal of Allergy Clinical Immunology","first-page":"63","article-title":"Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment","volume":"140","author":"Durack, J.","unstructured":"Durack, J., Lynch, S.V., Nariya, S., Bhakta, N.R., Beigelman, A., Castro, M., Dyer, A.M., Israel, E., Kraft, M., Martin, R.J., Mauger, D.T., Rosenberg, S.R., Sharp-King, T., White, S.R., Woodruff, P.G., Avila, P.C., Denlinger, L.C., Holguin, F., Lazarus, S.C., Lugogo, N., Moore, W.C., Peters, S.P., Que, L., Smith, L.J., Sorkness, C.A., Wechsler, M.E., Wenzel, S.E., Boushey, H.A. and Huang, Y.J., 2017. Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment. Journal of Allergy Clinical Immunology 140: 63-75."},{"key":"R000013","series-title":"Thorax","first-page":"1006","article-title":"Long-term persistence of human donor alveolar macrophages in lung transplant recipients","volume":"71","author":"Egu\u0131\u0301luz-Gracia, I.","unstructured":"Egu\u0131\u0301luz-Gracia, I., Schultz, H.H., Sikkeland, L.I., Danilova, E., Holm, A.M., Pronk, C.J., Agace, W.W., Iversen, M., Andersen, C., Jahnsen, F.L. and Baekkevold, E.S., 2016. Long-term persistence of human donor alveolar macrophages in lung transplant recipients. Thorax 71: 1006-1011."},{"key":"R000014","series-title":"Cell","first-page":"745","article-title":"NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis","volume":"145","author":"Elinav, E.","unstructured":"Elinav, E., Strowig, T., Kau, A.L., Henao-Mejia, J., Thaiss, C.A., Booth, C.J., Peaper, D.R., Bertin, J., Eisenbarth, S.C., Gordon, J.I. and Flavell, R.A., 2011. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145: 745-757."},{"key":"R000015","series-title":"Science","first-page":"1424","article-title":"Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora","volume":"298","author":"Fagarasan, S.","unstructured":"Fagarasan, S., Muramatsu, M., Suzuki, K., Nagaoka, H., Hiai, H. and Honjo, T., 2002. Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science 298: 1424-1427."},{"key":"R000016","series-title":"Science","article-title":"The long-term stability of the human gut microbiota","volume":"341","author":"Faith, J.J.","unstructured":"Faith, J.J., Guruge, J.L., Charbonneau, M., Subramanian, S., Seedorf, H., Goodman, A.L., Clemente, J.C., Knight, R., Heath, A.C., Leibel, R.L., Rosenbaum, M. and Gordon, J.I., 2013. The long-term stability of the human gut microbiota. Science 341: 1237439."},{"key":"R000017","series-title":"Frontiers in Microbiology","article-title":"Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances","volume":"6","author":"Francino, M.P.","unstructured":"Francino, M.P., 2016. Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances. Frontiers in Microbiology 6: 1543."},{"key":"R000018","series-title":"iScience","article-title":"Impact of probiotic Veillonella atypica FB0054 supplementation on anaerobic capacity and lactate","volume":"27","author":"Gross, K.","unstructured":"Gross, K., Santiago, M., Krieger, J.M., Hagele, A.M., Zielinska, K., Scheiman, J., J\u00e4ger, R., Kostic, A. and Kerksick, C.M., 2023. Impact of probiotic Veillonella atypica FB0054 supplementation on anaerobic capacity and lactate. iScience 27: 108643."},{"key":"R000019","series-title":"BMJ Open","article-title":"Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: study protocol for the randomised controlled phase II ReSScue trial","volume":"11","author":"Hoffmann-Vold, A.M.","unstructured":"Hoffmann-Vold, A.M., Fretheim, H.H., Sarna, V.K., Barua, I., Carstens, M.N., Distler, O., Khanna, D., Volkmann, E.R., Midtvedt, \u00d8., Didriksen, H., Dhainaut, A., Halse, A.K., Bakland, G., Pesonen, M., Olsen, I. and Molberg, \u00d8., 2021. Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: study protocol for the randomised controlled phase II ReSScue trial. BMJ Open 11: e048541."},{"key":"R000020","series-title":"Biology of Blood Marrow Transplantation","first-page":"640","article-title":"Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease","volume":"20","author":"Holler, E.","unstructured":"Holler, E., Butzhammer, P., Schmid, K., Hundsrucker, C., Koestler, J., Peter, K., Zhu, W., Sporrer, D., Hehlgans, T., Kreutz, M., Holler, B., Wolff, D., Edinger, M., Andreesen, R., Levine, J.E., Ferrara, J.L., Gessner, A., Spang, R. and Oefner, P.J., 2014. Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease. Biology of Blood Marrow Transplantation 20: 640-645."},{"key":"R000021","series-title":"Journal of Immunology Research","article-title":"Prevotella induces the production of Th17 cells in the colon of mice","volume":"2020","author":"Huang, Y.","unstructured":"Huang, Y., Tang, J., Cai, Z., Zhou, K., Chang, L., Bai, Y. and Ma, Y., 2020. Prevotella induces the production of Th17 cells in the colon of mice. Journal of Immunology Research 2020: 9607328."},{"key":"R000022","series-title":"Mucosal Immunology","first-page":"113","article-title":"Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation","volume":"14","author":"Iljazovic, A.","unstructured":"Iljazovic, A., Roy, U., Ga\u0301lvez, E.J.C., Lesker, T.R., Zhao, B., Gronow, A., Amend, L., Will, S.E., Hofmann, J.D., Pils, M.C., Schmidt-Hohagen, K., Neumann-Schaal, M. and Strowig, T., 2021. Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation. Mucosal Immunology 14: 113-124."},{"key":"R000023","series-title":"Trends in Immunology","first-page":"196","article-title":"Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?","volume":"39","author":"Jahnsen, F.L.","unstructured":"Jahnsen, F.L., B\u00e6kkevold, E.S., Hov, J.R. and Landsverk, O.J., 2018. Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut? Trends in Immunology 39: 196-208."},{"key":"R000024","series-title":"Journal Experimental Medicine","first-page":"903","article-title":"Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation","volume":"209","author":"Jenq, R.R.","unstructured":"Jenq, R.R., Ubeda, C., Taur, Y., Menezes, C.C., Khanin, R., Dudakov, J.A., Liu, C., West, M.L., Singer, N.V., Equinda, M.J., Gobourne, A., Lipuma, L., Young, L.F., Smith, O.M., Ghosh, A., Hanash, A.M., Goldberg, J.D., Aoyama, K., Blazar, B.R., Pamer, E.G. and van\u00a0den Brink, M.R.M., 2012. Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation. Journal Experimental Medicine 209: 903-911."},{"key":"R000025","series-title":"Mucosal Immunology","first-page":"1455","article-title":"Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation","volume":"9","author":"J\u00f8rgensen, S.F.","unstructured":"J\u00f8rgensen, S.F., Tr\u00f8seid, M., Kummen, M., Anmarkrud, J.A., Michelsen, A.E., Osnes, L.T., Holm, K., H\u00f8ivik, M.L., Rashidi, A., Dahl, C.P., Vesterhus, M., Halvorsen, B., Mollnes, T.E., Berge, R.K., Moum, B., Lundin, K.E., Fevang, B., Ueland, T., Karlsen, T.H., Aukrust, P. and Hov, J.R., 2016. Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation. Mucosal Immunology 9: 1455-1465."},{"key":"R000026","series-title":"Frontiers in Immunology","article-title":"Commentary: gut antibody deficiency in a mouse model of CVID results in spontaneous development of a gluten-sensitive enteropathy","volume":"11","author":"J\u00f8rgensen, S.F.","unstructured":"J\u00f8rgensen, S.F., Fevang, B. and Aukrust, P., 2020. Commentary: gut antibody deficiency in a mouse model of CVID results in spontaneous development of a gluten-sensitive enteropathy. Frontiers in Immunology 11: 1921."},{"key":"R000027","series-title":"New England Journal of Medicine","first-page":"2535","article-title":"Fecal microbiota transplantation for primary clostridium difficile infection","volume":"378","author":"Juul, F.E.","unstructured":"Juul, F.E., Garborg, K., Bretthauer, M., Skudal, H., \u00d8ines, M.N., Wiig, H., Rose, \u00d8., Seip, B., Lamont, J.T., Midtvedt, T., Valeur, J., Kalager, M., Holme, \u00d8., Helsingen, L., L\u00f8berg, M. and Adami, H.O., 2018. Fecal microbiota transplantation for primary clostridium difficile infection. New England Journal of Medicine 378: 2535-2536."},{"key":"R000028","series-title":"Journal of Experimental Medicine","article-title":"High microbiota reactivity of adult human intestinal IgA requires somatic mutations","volume":"217","author":"Kabbert, J.","unstructured":"Kabbert, J., Benckert, J., Rollenske, T., Hitch, T.C.A., Clavel, T., Cerovic, V., Wardemann, H. and Pabst, O., 2020. High microbiota reactivity of adult human intestinal IgA requires somatic mutations. Journal of Experimental Medicine 217: e20200275."},{"key":"R000029","series-title":"Scientific Reports","article-title":"Long-term taxonomic and functional stability of the gut microbiome from human fecal samples","volume":"13","author":"Kim, J.H.","unstructured":"Kim, J.H., Jeon, J.Y., Im, Y.J., Ha, N., Kim, J.K., Moon, S.J. and Kim, M.G., 2023. Long-term taxonomic and functional stability of the gut microbiome from human fecal samples. Scientific Reports 13: 114."},{"key":"R000030","series-title":"Nature Reviews Microbiology","first-page":"540","article-title":"Culturing the human microbiota and culturomics","volume":"16","author":"Lagier, J.C.","unstructured":"Lagier, J.C., Dubourg, G., Million, M., Cadoret, F., Bilen, M., Fenollar, F., Levasseur, A., Rolain, J.M., Fournier, P.E. and Raoult, D., 2018. Culturing the human microbiota and culturomics. Nature Reviews Microbiology 16: 540-550."},{"key":"R000031","series-title":"Journal of Experimental Medicine","first-page":"309","article-title":"Antibody-secreting plasma cells persist for decades in human intestine","volume":"214","author":"Landsverk, O.J.","unstructured":"Landsverk, O.J., Snir, O., Casado, R.B., Richter, L., Mold, J.E., Re\u0301u, P., Horneland, R., Paulsen, V., Yaqub, S., Aandahl, E.M., \u00d8yen, O.M., Thorarensen, H.S., Salehpour, M., Possnert, G., Frise\u0301n, J., Sollid, L.M., Baekkevold, E.S. and Jahnsen, F.L., 2017. Antibody-secreting plasma cells persist for decades in human intestine. Journal of Experimental Medicine 214: 309-317."},{"key":"R000032","series-title":"Immunology","first-page":"363","article-title":"The immune response to Prevotella bacteria in chronic inflammatory disease","volume":"151","author":"Larsen, J.M.","unstructured":"Larsen, J.M., 2017. The immune response to Prevotella bacteria in chronic inflammatory disease. Immunology 151: 363-374."},{"key":"R000033","series-title":"Proceedings of the National Academy of Sciences of the USA","article-title":"Microbiome signatures of progression toward celiac disease onset in at-risk children in a longitudinal prospective cohort study","volume":"118","author":"Leonard, M.M.","unstructured":"Leonard, M.M., Valitutti, F., Karathia, H., Pujolassos, M., Kenyon, V., Fanelli, B., Troisi, J., Subramanian, P., Camhi, S., Colucci, A., Serena, G., Cucchiara, S., Trovato, C.M., Malamisura, B., Francavilla, R., Elli, L., Hasan, N.A., Zomorrodi, A.R., Colwell, R., Fasano, A. and Team, C., 2021. Microbiome signatures of progression toward celiac disease onset in at-risk children in a longitudinal prospective cohort study. Proceedings of the National Academy of Sciences of the USA 118: e2020322118."},{"key":"R000034","series-title":"Journal of Translational Medicine","article-title":"Clinical significance of soluble immunoglobulins A and G and their coated bacteria in feces of patients with inflammatory bowel disease","volume":"16","author":"Lin, R.","unstructured":"Lin, R., Chen, H., Shu, W., Sun, M., Fang, L., Shi, Y., Pang, Z., Wu, W. and Liu, Z., 2018. Clinical significance of soluble immunoglobulins A and G and their coated bacteria in feces of patients with inflammatory bowel disease. Journal of Translational Medicine 16: 359."},{"key":"R000035","series-title":"Journal of Experimental Medicine","article-title":"Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells","volume":"218","author":"Lindeman, I.","unstructured":"Lindeman, I., Zhou, C., Eggesb\u00f8, L.M., Miao, Z., Polak, J., Lundin, K.E.A., Jahnsen, J., Qiao, S.W., Iversen, R. and Sollid, L.M., 2021. Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells. Journal of Experimental Medicine 218: e20200852."},{"key":"R000036","series-title":"Bone Marrow Transplantation","first-page":"1643","article-title":"Associations between acute gastrointestinal GvHD and the baseline gut microbiota of allogeneic hematopoietic stem cell transplant recipients and donors","volume":"52","author":"Liu, C.","unstructured":"Liu, C., Frank, D.N., Horch, M., Chau, S., Ir, D., Horch, E.A., Tretina, K., van Besien, K., Lozupone, C.A. and Nguyen, V.H., 2017. Associations between acute gastrointestinal GvHD and the baseline gut microbiota of allogeneic hematopoietic stem cell transplant recipients and donors. Bone Marrow Transplantation 52: 1643-1650."},{"key":"R000037","series-title":"Gut Microbes","first-page":"1","article-title":"Blautia-a new functional genus with potential probiotic properties?","volume":"13","author":"Liu, X.","unstructured":"Liu, X., Mao, B., Gu, J., Wu, J., Cui, S., Wang, G., Zhao, J., Zhang, H. and Chen, W., 2021. Blautia-a new functional genus with potential probiotic properties? Gut Microbes 13: 1-21."},{"key":"R000038","series-title":"Immunity","first-page":"118","article-title":"Human secretory IgM emerges from plasma cells clonally related to gut memory B cells and targets highly diverse commensals","volume":"47","author":"Magri, G.","unstructured":"Magri, G., Comerma, L., Pybus, M., Sintes, J., Llige\u0301, D., Segura-Garzo\u0301n, D., Bascones, S., Yeste, A., Grasset, E.K., Gutzeit, C., Uzzan, M., Ramanujam, M., van Zelm, M.C., Albero-Gonza\u0301lez, R., Vazquez, I., Iglesias, M., Serrano, S., Ma\u0301rquez, L., Mercade, E., Mehandru, S. and Cerutti, A., 2017. Human secretory IgM emerges from plasma cells clonally related to gut memory B cells and targets highly diverse commensals. Immunity 47: 118-134."},{"key":"R000039","series-title":"Immunological Investigations","first-page":"383","article-title":"Secretory IgA: arresting microbial pathogens at epithelial borders","volume":"39","author":"Mantis, N.J.","unstructured":"Mantis, N.J. and Forbes, S.J., 2010. Secretory IgA: arresting microbial pathogens at epithelial borders. Immunological Investigations 39: 383-406."},{"key":"R000040","series-title":"Nature Reviews Immunology","first-page":"9","article-title":"The impact of the gut microbiome on extra-intestinal autoimmune diseases","volume":"23","author":"Miyauchi, E.","unstructured":"Miyauchi, E., Shimokawa, C., Steimle, A., Desai, M.S. and Ohno, H., 2023. The impact of the gut microbiome on extra-intestinal autoimmune diseases. Nature Reviews Immunology 23: 9-23."},{"key":"R000041","series-title":"Nature","first-page":"162","article-title":"Mapping the T cell repertoire to a complex gut bacterial community","volume":"621","author":"Nagashima, K.","unstructured":"Nagashima, K., Zhao, A., Atabakhsh, K., Bae, M., Blum, J.E., Weakley, A., Jain, S., Meng, X., Cheng, A.G., Wang, M., Higginbottom, S., Dimas, A., Murugkar, P., Sattely, E.S., Moon, J.J., Balskus, E.P. and Fischbach, M.A., 2023. Mapping the T cell repertoire to a complex gut bacterial community. Nature 621: 162-170."},{"key":"R000042","series-title":"Nature","first-page":"321","article-title":"Tunable dynamics of B cell selection in gut germinal centres","volume":"588","author":"Nowosad, C.R.","unstructured":"Nowosad, C.R., Mesin, L., Castro, T.B.R., Wichmann, C., Donaldson, G.P., Araki, T., Schiepers, A., Lockhart, A.A.K., Bilate, A.M., Mucida, D. and Victora, G.D., 2020. Tunable dynamics of B cell selection in gut germinal centres. Nature 588: 321-326."},{"key":"R000043","series-title":"Nature Reviews Immunology","first-page":"821","article-title":"New concepts in the generation and functions of IgA","volume":"12","author":"Pabst, O.","unstructured":"Pabst, O., 2012. New concepts in the generation and functions of IgA. Nature Reviews Immunology 12: 821-832."},{"key":"R000044","series-title":"Cell","first-page":"1000","article-title":"Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease","volume":"158","author":"Palm, N.W.","unstructured":"Palm, N.W., de Zoete, M.R., Cullen, T.W., Barry, N.A., Stefanowski, J., Hao, L., Degnan, P.H., Hu, J., Peter, I., Zhang, W., Ruggiero, E., Cho, J.H., Goodman, A.L. and Flavell, R.A., 2014. Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Cell 158: 1000-1010."},{"key":"R000045","series-title":"New England Journal of Medicine","first-page":"822","article-title":"Microbiota as predictor of mortality in allogeneic hematopoietic-cell transplantation","volume":"382","author":"Peled, J.U.","unstructured":"Peled, J.U., Gomes, A.L.C., Devlin, S.M., Littmann, E.R., Taur, Y., Sung, A.D., Weber, D., Hashimoto, D., Slingerland, A.E., Slingerland, J.B., Maloy, M., Clurman, A.G., Stein-Thoeringer, C.K., Markey, K.A., Docampo, M.D., Burgos da\u00a0Silva, M., Khan, N., Gessner, A., Messina, J.A., Romero, K. and van\u00a0den Brink, M.R.M., 2020. Microbiota as predictor of mortality in allogeneic hematopoietic-cell transplantation. New England Journal of Medicine 382: 822-834."},{"key":"R000046","series-title":"Blood","first-page":"401","article-title":"Microbiome-intestine cross talk during acute graft-versus-host disease","volume":"136","author":"Rafei, H.","unstructured":"Rafei, H. and Jenq, R.R., 2020. Microbiome-intestine cross talk during acute graft-versus-host disease. Blood 136: 401-409."},{"key":"R000047","series-title":"Clinical Infectious Diseases","first-page":"S77","article-title":"Determining the long-term effect of antibiotic administration on the human normal intestinal microbiota using culture and pyrosequencing methods","volume":"60","author":"Rashid, M.U.","unstructured":"Rashid, M.U., Zaura, E., Buijs, M.J., Keijser, B.J., Crielaard, W., Nord, C.E. and Weintraub, A., 2015. Determining the long-term effect of antibiotic administration on the human normal intestinal microbiota using culture and pyrosequencing methods. Clinical Infectious Diseases 60: S77-84."},{"key":"R000048","series-title":"European Journal of Immunology","first-page":"2959","article-title":"Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice","volume":"42","author":"Reikvam, D.H.","unstructured":"Reikvam, D.H., Derrien, M., Islam, R., Erofeev, A., Grcic, V., Sandvik, A., Gaustad, P., Meza-Zepeda, L.A., Jahnsen, F.L., Smidt, H. and Johansen, F.E., 2012. Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice. European Journal of Immunology 42: 2959-2970."},{"key":"R000049","series-title":"Microbial Ecology in Health Disease","article-title":"The composition of the gut microbiota throughout life, with an emphasis on early life","volume":"26","author":"Rodr\u0131\u0301guez, J.M.","unstructured":"Rodr\u0131\u0301guez, J.M., Murphy, K., Stanton, C., Ross, R.P., Kober, O.I., Juge, N., Avershina, E., Rudi, K., Narbad, A., Jenmalm, M.C., Marchesi, J.R. and Collado, M.C., 2015. The composition of the gut microbiota throughout life, with an emphasis on early life. Microbial Ecology in Health Disease 26: 26050."},{"key":"R000050","series-title":"Cell Host Microbe","first-page":"83","article-title":"Immunoglobulin A targets a unique subset of the microbiota in inflammatory bowel disease","volume":"29","author":"Shapiro, J.M.","unstructured":"Shapiro, J.M., de Zoete, M.R., Palm, N.W., Laenen, Y., Bright, R., Mallette, M., Bu, K., Bielecka, A.A., Xu, F., Hurtado-Lorenzo, A., Shah, S.A., Cho, J.H., LeLeiko, N.S., Sands, B.E., Flavell, R.A. and Clemente, J.C., 2021. Immunoglobulin A targets a unique subset of the microbiota in inflammatory bowel disease. Cell Host Microbe 29: 83-93."},{"key":"R000051","series-title":"Nature Reviews Gastroenterology and Hepatology","first-page":"120","article-title":"Tango of B cells with T cells in the making of secretory antibodies to gut bacteria","volume":"20","author":"Sollid, L.M.","unstructured":"Sollid, L.M. and Iversen, R., 2023. Tango of B cells with T cells in the making of secretory antibodies to gut bacteria. Nature Reviews Gastroenterology and Hepatology 20: 120-128."},{"key":"R000052","series-title":"The Journal of Experimental Medicine","article-title":"Human IgA binds a diverse array of commensal bacteria","volume":"217","author":"Sterlin, D.","unstructured":"Sterlin, D., Fadlallah, J., Adams, O., Fieschi, C., Parizot, C., Dorgham, K., Rajkumar, A., Autaa, G., El-Kafsi, H., Charuel, J.L., Juste, C., J\u00f6nsson, F., Candela, T., Wardemann, H., Aubry, A., Capito, C., Brisson, H., Tresallet, C., Cummings, R.D., Larsen, M. and Gorochov, G., 2020. Human IgA binds a diverse array of commensal bacteria. The Journal of Experimental Medicine 217: e20181635."},{"key":"R000053","series-title":"Proceedings of the National Academy of Sciences of the USA","first-page":"1981","article-title":"Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut","volume":"101","author":"Suzuki, K.","unstructured":"Suzuki, K., Meek, B., Doi, Y., Muramatsu, M., Chiba, T., Honjo, T. and Fagarasan, S., 2004. Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proceedings of the National Academy of Sciences of the USA 101: 1981-1986."},{"key":"R000054","series-title":"The Lancet Gastroenterology and Hepatology","first-page":"747","article-title":"The microbiota-gut-brain axis in obesity","volume":"2","author":"Torres-Fuentes, C.","unstructured":"Torres-Fuentes, C., Schellekens, H., Dinan, T.G. and Cryan, J.F., 2017. The microbiota-gut-brain axis in obesity. The Lancet Gastroenterology and Hepatology 2: 747-756."},{"key":"R000055","series-title":"Nutrition Reviews","first-page":"S38","article-title":"Defining the human microbiome","volume":"70","author":"Ursell, L.K.","unstructured":"Ursell, L.K., Metcalf, J.L., Parfrey, L.W. and Knight, R., 2012. Defining the human microbiome. Nutrition Reviews 70: S38-44."},{"key":"R000056","series-title":"Nature Medicine","first-page":"766","article-title":"Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity","volume":"28","author":"Uzzan, M.","unstructured":"Uzzan, M., Martin, J.C., Mesin, L., Livanos, A.E., Castro-Dopico, T., Huang, R., Petralia, F., Magri, G., Kumar, S., Zhao, Q., Rosenstein, A.K., Tokuyama, M., Sharma, K., Ungaro, R., Kosoy, R., Jha, D., Fischer, J., Singh, H., Keir, M.E., Ramamoorthi, N. and Mehandru, S., 2022. Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity. Nature Medicine 28: 766-779."},{"key":"R000057","series-title":"Nature Immunology","first-page":"264","article-title":"Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense","volume":"12","author":"Wei, M.","unstructured":"Wei, M., Shinkura, R., Doi, Y., Maruya, M., Fagarasan, S. and Honjo, T., 2011. Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense. Nature Immunology 12: 264-270."},{"key":"R000001","series-title":"Transplant Cellular Therapy","first-page":"e1","article-title":"Calprotectin expressing donor-derived macrophages increase in acute gastrointestinal graft-versus-host disease","volume":"28","author":"Aasebo, A.T.","unstructured":"Aasebo, A.T., Gedde-Dahl, T., Reims, H.M., Baekkevold, E.S. and Jahnsen, F.L., 2022. Calprotectin expressing donor-derived macrophages increase in acute gastrointestinal graft-versus-host disease. Transplant Cellular Therapy 28: e1-248."},{"key":"R000002","series-title":"PeerJ","article-title":"Compact graphical representation of phylogenetic data and metadata with GraPhlAn","volume":"3","author":"Asnicar, F.","unstructured":"Asnicar, F., Weingart, G., Tickle, T.L., Huttenhower, C. and Segata, N., 2015. Compact graphical representation of phylogenetic data and metadata with GraPhlAn. PeerJ 3: e1029."},{"key":"R000003","series-title":"Mucosal Immunology","first-page":"402","article-title":"CD4(+) T cells persist for years in the human small intestine and display a T(H)1 cytokine profile","volume":"14","author":"Bartolome\u0301-Casado, R.","unstructured":"Bartolome\u0301-Casado, R., Landsverk, O.J.B., Chauhan, S.K., S\u00e6tre, F., Hagen, K.T., Yaqub, S., \u00d8yen, O., Horneland, R., Aandahl, E.M., Aabakken, L., B\u00e6kkevold, E.S. and Jahnsen, F.L., 2021. CD4(+) T cells persist for years in the human small intestine and display a T(H)1 cytokine profile. Mucosal Immunology 14: 402-410."},{"key":"R000004","series-title":"Best Practice and Research Clinical Gastroenterology","article-title":"Therapeutic potential of an anaerobic cultured human intestinal microbiota, ACHIM, for treatment of IBS","volume":"40-41","author":"Benno, P.","unstructured":"Benno, P., Norin, E., Midtvedt, T. and Hellstr\u00f6m, P.M., 2019. Therapeutic potential of an anaerobic cultured human intestinal microbiota, ACHIM, for treatment of IBS. Best Practice and Research Clinical Gastroenterology 40-41: 101607."},{"key":"R000005","series-title":"Immunological Reviews","first-page":"32","article-title":"Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties","volume":"206","author":"Brandtzaeg, P.","unstructured":"Brandtzaeg, P. and Johansen, F.E., 2005. Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties. Immunological Reviews 206: 32-63."},{"key":"R000006","series-title":"Immunity","first-page":"211","article-title":"IgA Responses to Microbiota","volume":"49","author":"Bunker, J.J.","unstructured":"Bunker, J.J. and Bendelac, A., 2018. IgA Responses to Microbiota. Immunity 49: 211-224."},{"key":"R000007","series-title":"Science","article-title":"Natural polyreactive IgA antibodies coat the intestinal microbiota","volume":"358","author":"Bunker, J.J.","unstructured":"Bunker, J.J., Erickson, S.A., Flynn, T.M., Henry, C., Koval, J.C., Meisel, M., Jabri, B., Antonopoulos, D.A., Wilson, P.C. and Bendelac, A., 2017. Natural polyreactive IgA antibodies coat the intestinal microbiota. Science 358: eaan6619."},{"key":"R000008","series-title":"Scientific Reports","article-title":"IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM","volume":"9","author":"Catanzaro, J.R.","unstructured":"Catanzaro, J.R., Strauss, J.D., Bielecka, A., Porto, A.F., Lobo, F.M., Urban, A., Schofield, W.B. and Palm, N.W., 2019. IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM. Scientific Reports 9: 13574."},{"key":"R000009","series-title":"Nature","first-page":"421","article-title":"BCR selection and affinity maturation in Peyer\u2019s patch germinal centres","volume":"582","author":"Chen, H.","unstructured":"Chen, H., Zhang, Y., Ye, A.Y., Du, Z., Xu, M., Lee, C.S., Hwang, J.K., Kyritsis, N., Ba, Z., Neuberg, D., Littman, D.R. and Alt, F.W., 2020. BCR selection and affinity maturation in Peyer\u2019s patch germinal centres. Nature 582: 421-425."},{"key":"R000010","series-title":"Journal of Clinical Investigation","first-page":"4624","article-title":"Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease","volume":"130","author":"Divito, S.J.","unstructured":"Divito, S.J., Aaseb\u00f8, A.T., Matos, T.R., Hsieh, P.C., Collin, M., Elco, C.P., O\u2019Malley, J.T., B\u00e6kkevold, E.S., Reims, H., Gedde-Dahl, T., Hagerstrom, M., Hilaire, J., Lian, J.W., Milford, E.L., Pinkus, G.S., Ho, V.T., Soiffer, R.J., Kim, H.T., Mihm, M.C., Ritz, J., Guleria, I., Cutler, C.S., Clark, R.A., Jahnsen, F.L. and Kupper, T.S., 2020. Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease. Journal of Clinical Investigation 130: 4624-4636."},{"key":"R000011","series-title":"Journal of Experimental Medicine","first-page":"20","article-title":"The gut microbiome: Relationships with disease and opportunities for therapy","volume":"216","author":"Durack, J.","unstructured":"Durack, J. and Lynch, S.V., 2019. The gut microbiome: Relationships with disease and opportunities for therapy. Journal of Experimental Medicine 216: 20-40."},{"key":"R000012","series-title":"Journal of Allergy Clinical Immunology","first-page":"63","article-title":"Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment","volume":"140","author":"Durack, J.","unstructured":"Durack, J., Lynch, S.V., Nariya, S., Bhakta, N.R., Beigelman, A., Castro, M., Dyer, A.M., Israel, E., Kraft, M., Martin, R.J., Mauger, D.T., Rosenberg, S.R., Sharp-King, T., White, S.R., Woodruff, P.G., Avila, P.C., Denlinger, L.C., Holguin, F., Lazarus, S.C., Lugogo, N., Moore, W.C., Peters, S.P., Que, L., Smith, L.J., Sorkness, C.A., Wechsler, M.E., Wenzel, S.E., Boushey, H.A. and Huang, Y.J., 2017. Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment. Journal of Allergy Clinical Immunology 140: 63-75."},{"key":"R000013","series-title":"Thorax","first-page":"1006","article-title":"Long-term persistence of human donor alveolar macrophages in lung transplant recipients","volume":"71","author":"Egu\u0131\u0301luz-Gracia, I.","unstructured":"Egu\u0131\u0301luz-Gracia, I., Schultz, H.H., Sikkeland, L.I., Danilova, E., Holm, A.M., Pronk, C.J., Agace, W.W., Iversen, M., Andersen, C., Jahnsen, F.L. and Baekkevold, E.S., 2016. Long-term persistence of human donor alveolar macrophages in lung transplant recipients. Thorax 71: 1006-1011."},{"key":"R000014","series-title":"Cell","first-page":"745","article-title":"NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis","volume":"145","author":"Elinav, E.","unstructured":"Elinav, E., Strowig, T., Kau, A.L., Henao-Mejia, J., Thaiss, C.A., Booth, C.J., Peaper, D.R., Bertin, J., Eisenbarth, S.C., Gordon, J.I. and Flavell, R.A., 2011. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145: 745-757."},{"key":"R000015","series-title":"Science","first-page":"1424","article-title":"Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora","volume":"298","author":"Fagarasan, S.","unstructured":"Fagarasan, S., Muramatsu, M., Suzuki, K., Nagaoka, H., Hiai, H. and Honjo, T., 2002. Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science 298: 1424-1427."},{"key":"R000016","series-title":"Science","article-title":"The long-term stability of the human gut microbiota","volume":"341","author":"Faith, J.J.","unstructured":"Faith, J.J., Guruge, J.L., Charbonneau, M., Subramanian, S., Seedorf, H., Goodman, A.L., Clemente, J.C., Knight, R., Heath, A.C., Leibel, R.L., Rosenbaum, M. and Gordon, J.I., 2013. The long-term stability of the human gut microbiota. Science 341: 1237439."},{"key":"R000017","series-title":"Frontiers in Microbiology","article-title":"Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances","volume":"6","author":"Francino, M.P.","unstructured":"Francino, M.P., 2016. Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances. Frontiers in Microbiology 6: 1543."},{"key":"R000018","series-title":"iScience","article-title":"Impact of probiotic Veillonella atypica FB0054 supplementation on anaerobic capacity and lactate","volume":"27","author":"Gross, K.","unstructured":"Gross, K., Santiago, M., Krieger, J.M., Hagele, A.M., Zielinska, K., Scheiman, J., J\u00e4ger, R., Kostic, A. and Kerksick, C.M., 2023. Impact of probiotic Veillonella atypica FB0054 supplementation on anaerobic capacity and lactate. iScience 27: 108643."},{"key":"R000019","series-title":"BMJ Open","article-title":"Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: study protocol for the randomised controlled phase II ReSScue trial","volume":"11","author":"Hoffmann-Vold, A.M.","unstructured":"Hoffmann-Vold, A.M., Fretheim, H.H., Sarna, V.K., Barua, I., Carstens, M.N., Distler, O., Khanna, D., Volkmann, E.R., Midtvedt, \u00d8., Didriksen, H., Dhainaut, A., Halse, A.K., Bakland, G., Pesonen, M., Olsen, I. and Molberg, \u00d8., 2021. Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: study protocol for the randomised controlled phase II ReSScue trial. BMJ Open 11: e048541."},{"key":"R000020","series-title":"Biology of Blood Marrow Transplantation","first-page":"640","article-title":"Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease","volume":"20","author":"Holler, E.","unstructured":"Holler, E., Butzhammer, P., Schmid, K., Hundsrucker, C., Koestler, J., Peter, K., Zhu, W., Sporrer, D., Hehlgans, T., Kreutz, M., Holler, B., Wolff, D., Edinger, M., Andreesen, R., Levine, J.E., Ferrara, J.L., Gessner, A., Spang, R. and Oefner, P.J., 2014. Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease. Biology of Blood Marrow Transplantation 20: 640-645."},{"key":"R000021","series-title":"Journal of Immunology Research","article-title":"Prevotella induces the production of Th17 cells in the colon of mice","volume":"2020","author":"Huang, Y.","unstructured":"Huang, Y., Tang, J., Cai, Z., Zhou, K., Chang, L., Bai, Y. and Ma, Y., 2020. Prevotella induces the production of Th17 cells in the colon of mice. Journal of Immunology Research 2020: 9607328."},{"key":"R000022","series-title":"Mucosal Immunology","first-page":"113","article-title":"Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation","volume":"14","author":"Iljazovic, A.","unstructured":"Iljazovic, A., Roy, U., Ga\u0301lvez, E.J.C., Lesker, T.R., Zhao, B., Gronow, A., Amend, L., Will, S.E., Hofmann, J.D., Pils, M.C., Schmidt-Hohagen, K., Neumann-Schaal, M. and Strowig, T., 2021. Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation. Mucosal Immunology 14: 113-124."},{"key":"R000023","series-title":"Trends in Immunology","first-page":"196","article-title":"Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?","volume":"39","author":"Jahnsen, F.L.","unstructured":"Jahnsen, F.L., B\u00e6kkevold, E.S., Hov, J.R. and Landsverk, O.J., 2018. Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut? Trends in Immunology 39: 196-208."},{"key":"R000024","series-title":"Journal Experimental Medicine","first-page":"903","article-title":"Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation","volume":"209","author":"Jenq, R.R.","unstructured":"Jenq, R.R., Ubeda, C., Taur, Y., Menezes, C.C., Khanin, R., Dudakov, J.A., Liu, C., West, M.L., Singer, N.V., Equinda, M.J., Gobourne, A., Lipuma, L., Young, L.F., Smith, O.M., Ghosh, A., Hanash, A.M., Goldberg, J.D., Aoyama, K., Blazar, B.R., Pamer, E.G. and van\u00a0den Brink, M.R.M., 2012. Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation. Journal Experimental Medicine 209: 903-911."},{"key":"R000025","series-title":"Mucosal Immunology","first-page":"1455","article-title":"Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation","volume":"9","author":"J\u00f8rgensen, S.F.","unstructured":"J\u00f8rgensen, S.F., Tr\u00f8seid, M., Kummen, M., Anmarkrud, J.A., Michelsen, A.E., Osnes, L.T., Holm, K., H\u00f8ivik, M.L., Rashidi, A., Dahl, C.P., Vesterhus, M., Halvorsen, B., Mollnes, T.E., Berge, R.K., Moum, B., Lundin, K.E., Fevang, B., Ueland, T., Karlsen, T.H., Aukrust, P. and Hov, J.R., 2016. Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation. Mucosal Immunology 9: 1455-1465."},{"key":"R000026","series-title":"Frontiers in Immunology","article-title":"Commentary: gut antibody deficiency in a mouse model of CVID results in spontaneous development of a gluten-sensitive enteropathy","volume":"11","author":"J\u00f8rgensen, S.F.","unstructured":"J\u00f8rgensen, S.F., Fevang, B. and Aukrust, P., 2020. Commentary: gut antibody deficiency in a mouse model of CVID results in spontaneous development of a gluten-sensitive enteropathy. Frontiers in Immunology 11: 1921."},{"key":"R000027","series-title":"New England Journal of Medicine","first-page":"2535","article-title":"Fecal microbiota transplantation for primary clostridium difficile infection","volume":"378","author":"Juul, F.E.","unstructured":"Juul, F.E., Garborg, K., Bretthauer, M., Skudal, H., \u00d8ines, M.N., Wiig, H., Rose, \u00d8., Seip, B., Lamont, J.T., Midtvedt, T., Valeur, J., Kalager, M., Holme, \u00d8., Helsingen, L., L\u00f8berg, M. and Adami, H.O., 2018. Fecal microbiota transplantation for primary clostridium difficile infection. New England Journal of Medicine 378: 2535-2536."},{"key":"R000028","series-title":"Journal of Experimental Medicine","article-title":"High microbiota reactivity of adult human intestinal IgA requires somatic mutations","volume":"217","author":"Kabbert, J.","unstructured":"Kabbert, J., Benckert, J., Rollenske, T., Hitch, T.C.A., Clavel, T., Cerovic, V., Wardemann, H. and Pabst, O., 2020. High microbiota reactivity of adult human intestinal IgA requires somatic mutations. Journal of Experimental Medicine 217: e20200275."},{"key":"R000029","series-title":"Scientific Reports","article-title":"Long-term taxonomic and functional stability of the gut microbiome from human fecal samples","volume":"13","author":"Kim, J.H.","unstructured":"Kim, J.H., Jeon, J.Y., Im, Y.J., Ha, N., Kim, J.K., Moon, S.J. and Kim, M.G., 2023. Long-term taxonomic and functional stability of the gut microbiome from human fecal samples. Scientific Reports 13: 114."},{"key":"R000030","series-title":"Nature Reviews Microbiology","first-page":"540","article-title":"Culturing the human microbiota and culturomics","volume":"16","author":"Lagier, J.C.","unstructured":"Lagier, J.C., Dubourg, G., Million, M., Cadoret, F., Bilen, M., Fenollar, F., Levasseur, A., Rolain, J.M., Fournier, P.E. and Raoult, D., 2018. Culturing the human microbiota and culturomics. Nature Reviews Microbiology 16: 540-550."},{"key":"R000031","series-title":"Journal of Experimental Medicine","first-page":"309","article-title":"Antibody-secreting plasma cells persist for decades in human intestine","volume":"214","author":"Landsverk, O.J.","unstructured":"Landsverk, O.J., Snir, O., Casado, R.B., Richter, L., Mold, J.E., Re\u0301u, P., Horneland, R., Paulsen, V., Yaqub, S., Aandahl, E.M., \u00d8yen, O.M., Thorarensen, H.S., Salehpour, M., Possnert, G., Frise\u0301n, J., Sollid, L.M., Baekkevold, E.S. and Jahnsen, F.L., 2017. Antibody-secreting plasma cells persist for decades in human intestine. Journal of Experimental Medicine 214: 309-317."},{"key":"R000032","series-title":"Immunology","first-page":"363","article-title":"The immune response to Prevotella bacteria in chronic inflammatory disease","volume":"151","author":"Larsen, J.M.","unstructured":"Larsen, J.M., 2017. The immune response to Prevotella bacteria in chronic inflammatory disease. Immunology 151: 363-374."},{"key":"R000033","series-title":"Proceedings of the National Academy of Sciences of the USA","article-title":"Microbiome signatures of progression toward celiac disease onset in at-risk children in a longitudinal prospective cohort study","volume":"118","author":"Leonard, M.M.","unstructured":"Leonard, M.M., Valitutti, F., Karathia, H., Pujolassos, M., Kenyon, V., Fanelli, B., Troisi, J., Subramanian, P., Camhi, S., Colucci, A., Serena, G., Cucchiara, S., Trovato, C.M., Malamisura, B., Francavilla, R., Elli, L., Hasan, N.A., Zomorrodi, A.R., Colwell, R., Fasano, A. and Team, C., 2021. Microbiome signatures of progression toward celiac disease onset in at-risk children in a longitudinal prospective cohort study. Proceedings of the National Academy of Sciences of the USA 118: e2020322118."},{"key":"R000034","series-title":"Journal of Translational Medicine","article-title":"Clinical significance of soluble immunoglobulins A and G and their coated bacteria in feces of patients with inflammatory bowel disease","volume":"16","author":"Lin, R.","unstructured":"Lin, R., Chen, H., Shu, W., Sun, M., Fang, L., Shi, Y., Pang, Z., Wu, W. and Liu, Z., 2018. Clinical significance of soluble immunoglobulins A and G and their coated bacteria in feces of patients with inflammatory bowel disease. Journal of Translational Medicine 16: 359."},{"key":"R000035","series-title":"Journal of Experimental Medicine","article-title":"Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells","volume":"218","author":"Lindeman, I.","unstructured":"Lindeman, I., Zhou, C., Eggesb\u00f8, L.M., Miao, Z., Polak, J., Lundin, K.E.A., Jahnsen, J., Qiao, S.W., Iversen, R. and Sollid, L.M., 2021. Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells. Journal of Experimental Medicine 218: e20200852."},{"key":"R000036","series-title":"Bone Marrow Transplantation","first-page":"1643","article-title":"Associations between acute gastrointestinal GvHD and the baseline gut microbiota of allogeneic hematopoietic stem cell transplant recipients and donors","volume":"52","author":"Liu, C.","unstructured":"Liu, C., Frank, D.N., Horch, M., Chau, S., Ir, D., Horch, E.A., Tretina, K., van Besien, K., Lozupone, C.A. and Nguyen, V.H., 2017. Associations between acute gastrointestinal GvHD and the baseline gut microbiota of allogeneic hematopoietic stem cell transplant recipients and donors. Bone Marrow Transplantation 52: 1643-1650."},{"key":"R000037","series-title":"Gut Microbes","first-page":"1","article-title":"Blautia-a new functional genus with potential probiotic properties?","volume":"13","author":"Liu, X.","unstructured":"Liu, X., Mao, B., Gu, J., Wu, J., Cui, S., Wang, G., Zhao, J., Zhang, H. and Chen, W., 2021. Blautia-a new functional genus with potential probiotic properties? Gut Microbes 13: 1-21."},{"key":"R000038","series-title":"Immunity","first-page":"118","article-title":"Human secretory IgM emerges from plasma cells clonally related to gut memory B cells and targets highly diverse commensals","volume":"47","author":"Magri, G.","unstructured":"Magri, G., Comerma, L., Pybus, M., Sintes, J., Llige\u0301, D., Segura-Garzo\u0301n, D., Bascones, S., Yeste, A., Grasset, E.K., Gutzeit, C., Uzzan, M., Ramanujam, M., van Zelm, M.C., Albero-Gonza\u0301lez, R., Vazquez, I., Iglesias, M., Serrano, S., Ma\u0301rquez, L., Mercade, E., Mehandru, S. and Cerutti, A., 2017. Human secretory IgM emerges from plasma cells clonally related to gut memory B cells and targets highly diverse commensals. Immunity 47: 118-134."},{"key":"R000039","series-title":"Immunological Investigations","first-page":"383","article-title":"Secretory IgA: arresting microbial pathogens at epithelial borders","volume":"39","author":"Mantis, N.J.","unstructured":"Mantis, N.J. and Forbes, S.J., 2010. Secretory IgA: arresting microbial pathogens at epithelial borders. Immunological Investigations 39: 383-406."},{"key":"R000040","series-title":"Nature Reviews Immunology","first-page":"9","article-title":"The impact of the gut microbiome on extra-intestinal autoimmune diseases","volume":"23","author":"Miyauchi, E.","unstructured":"Miyauchi, E., Shimokawa, C., Steimle, A., Desai, M.S. and Ohno, H., 2023. The impact of the gut microbiome on extra-intestinal autoimmune diseases. Nature Reviews Immunology 23: 9-23."},{"key":"R000041","series-title":"Nature","first-page":"162","article-title":"Mapping the T cell repertoire to a complex gut bacterial community","volume":"621","author":"Nagashima, K.","unstructured":"Nagashima, K., Zhao, A., Atabakhsh, K., Bae, M., Blum, J.E., Weakley, A., Jain, S., Meng, X., Cheng, A.G., Wang, M., Higginbottom, S., Dimas, A., Murugkar, P., Sattely, E.S., Moon, J.J., Balskus, E.P. and Fischbach, M.A., 2023. Mapping the T cell repertoire to a complex gut bacterial community. Nature 621: 162-170."},{"key":"R000042","series-title":"Nature","first-page":"321","article-title":"Tunable dynamics of B cell selection in gut germinal centres","volume":"588","author":"Nowosad, C.R.","unstructured":"Nowosad, C.R., Mesin, L., Castro, T.B.R., Wichmann, C., Donaldson, G.P., Araki, T., Schiepers, A., Lockhart, A.A.K., Bilate, A.M., Mucida, D. and Victora, G.D., 2020. Tunable dynamics of B cell selection in gut germinal centres. Nature 588: 321-326."},{"key":"R000043","series-title":"Nature Reviews Immunology","first-page":"821","article-title":"New concepts in the generation and functions of IgA","volume":"12","author":"Pabst, O.","unstructured":"Pabst, O., 2012. New concepts in the generation and functions of IgA. Nature Reviews Immunology 12: 821-832."},{"key":"R000044","series-title":"Cell","first-page":"1000","article-title":"Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease","volume":"158","author":"Palm, N.W.","unstructured":"Palm, N.W., de Zoete, M.R., Cullen, T.W., Barry, N.A., Stefanowski, J., Hao, L., Degnan, P.H., Hu, J., Peter, I., Zhang, W., Ruggiero, E., Cho, J.H., Goodman, A.L. and Flavell, R.A., 2014. Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Cell 158: 1000-1010."},{"key":"R000045","series-title":"New England Journal of Medicine","first-page":"822","article-title":"Microbiota as predictor of mortality in allogeneic hematopoietic-cell transplantation","volume":"382","author":"Peled, J.U.","unstructured":"Peled, J.U., Gomes, A.L.C., Devlin, S.M., Littmann, E.R., Taur, Y., Sung, A.D., Weber, D., Hashimoto, D., Slingerland, A.E., Slingerland, J.B., Maloy, M., Clurman, A.G., Stein-Thoeringer, C.K., Markey, K.A., Docampo, M.D., Burgos da\u00a0Silva, M., Khan, N., Gessner, A., Messina, J.A., Romero, K. and van\u00a0den Brink, M.R.M., 2020. Microbiota as predictor of mortality in allogeneic hematopoietic-cell transplantation. New England Journal of Medicine 382: 822-834."},{"key":"R000046","series-title":"Blood","first-page":"401","article-title":"Microbiome-intestine cross talk during acute graft-versus-host disease","volume":"136","author":"Rafei, H.","unstructured":"Rafei, H. and Jenq, R.R., 2020. Microbiome-intestine cross talk during acute graft-versus-host disease. Blood 136: 401-409."},{"key":"R000047","series-title":"Clinical Infectious Diseases","first-page":"S77","article-title":"Determining the long-term effect of antibiotic administration on the human normal intestinal microbiota using culture and pyrosequencing methods","volume":"60","author":"Rashid, M.U.","unstructured":"Rashid, M.U., Zaura, E., Buijs, M.J., Keijser, B.J., Crielaard, W., Nord, C.E. and Weintraub, A., 2015. Determining the long-term effect of antibiotic administration on the human normal intestinal microbiota using culture and pyrosequencing methods. Clinical Infectious Diseases 60: S77-84."},{"key":"R000048","series-title":"European Journal of Immunology","first-page":"2959","article-title":"Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice","volume":"42","author":"Reikvam, D.H.","unstructured":"Reikvam, D.H., Derrien, M., Islam, R., Erofeev, A., Grcic, V., Sandvik, A., Gaustad, P., Meza-Zepeda, L.A., Jahnsen, F.L., Smidt, H. and Johansen, F.E., 2012. Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice. European Journal of Immunology 42: 2959-2970."},{"key":"R000049","series-title":"Microbial Ecology in Health Disease","article-title":"The composition of the gut microbiota throughout life, with an emphasis on early life","volume":"26","author":"Rodr\u0131\u0301guez, J.M.","unstructured":"Rodr\u0131\u0301guez, J.M., Murphy, K., Stanton, C., Ross, R.P., Kober, O.I., Juge, N., Avershina, E., Rudi, K., Narbad, A., Jenmalm, M.C., Marchesi, J.R. and Collado, M.C., 2015. The composition of the gut microbiota throughout life, with an emphasis on early life. Microbial Ecology in Health Disease 26: 26050."},{"key":"R000050","series-title":"Cell Host Microbe","first-page":"83","article-title":"Immunoglobulin A targets a unique subset of the microbiota in inflammatory bowel disease","volume":"29","author":"Shapiro, J.M.","unstructured":"Shapiro, J.M., de Zoete, M.R., Palm, N.W., Laenen, Y., Bright, R., Mallette, M., Bu, K., Bielecka, A.A., Xu, F., Hurtado-Lorenzo, A., Shah, S.A., Cho, J.H., LeLeiko, N.S., Sands, B.E., Flavell, R.A. and Clemente, J.C., 2021. Immunoglobulin A targets a unique subset of the microbiota in inflammatory bowel disease. Cell Host Microbe 29: 83-93."},{"key":"R000051","series-title":"Nature Reviews Gastroenterology and Hepatology","first-page":"120","article-title":"Tango of B cells with T cells in the making of secretory antibodies to gut bacteria","volume":"20","author":"Sollid, L.M.","unstructured":"Sollid, L.M. and Iversen, R., 2023. Tango of B cells with T cells in the making of secretory antibodies to gut bacteria. Nature Reviews Gastroenterology and Hepatology 20: 120-128."},{"key":"R000052","series-title":"The Journal of Experimental Medicine","article-title":"Human IgA binds a diverse array of commensal bacteria","volume":"217","author":"Sterlin, D.","unstructured":"Sterlin, D., Fadlallah, J., Adams, O., Fieschi, C., Parizot, C., Dorgham, K., Rajkumar, A., Autaa, G., El-Kafsi, H., Charuel, J.L., Juste, C., J\u00f6nsson, F., Candela, T., Wardemann, H., Aubry, A., Capito, C., Brisson, H., Tresallet, C., Cummings, R.D., Larsen, M. and Gorochov, G., 2020. Human IgA binds a diverse array of commensal bacteria. The Journal of Experimental Medicine 217: e20181635."},{"key":"R000053","series-title":"Proceedings of the National Academy of Sciences of the USA","first-page":"1981","article-title":"Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut","volume":"101","author":"Suzuki, K.","unstructured":"Suzuki, K., Meek, B., Doi, Y., Muramatsu, M., Chiba, T., Honjo, T. and Fagarasan, S., 2004. Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proceedings of the National Academy of Sciences of the USA 101: 1981-1986."},{"key":"R000054","series-title":"The Lancet Gastroenterology and Hepatology","first-page":"747","article-title":"The microbiota-gut-brain axis in obesity","volume":"2","author":"Torres-Fuentes, C.","unstructured":"Torres-Fuentes, C., Schellekens, H., Dinan, T.G. and Cryan, J.F., 2017. The microbiota-gut-brain axis in obesity. The Lancet Gastroenterology and Hepatology 2: 747-756."},{"key":"R000055","series-title":"Nutrition Reviews","first-page":"S38","article-title":"Defining the human microbiome","volume":"70","author":"Ursell, L.K.","unstructured":"Ursell, L.K., Metcalf, J.L., Parfrey, L.W. and Knight, R., 2012. Defining the human microbiome. Nutrition Reviews 70: S38-44."},{"key":"R000056","series-title":"Nature Medicine","first-page":"766","article-title":"Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity","volume":"28","author":"Uzzan, M.","unstructured":"Uzzan, M., Martin, J.C., Mesin, L., Livanos, A.E., Castro-Dopico, T., Huang, R., Petralia, F., Magri, G., Kumar, S., Zhao, Q., Rosenstein, A.K., Tokuyama, M., Sharma, K., Ungaro, R., Kosoy, R., Jha, D., Fischer, J., Singh, H., Keir, M.E., Ramamoorthi, N. and Mehandru, S., 2022. Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity. Nature Medicine 28: 766-779."},{"key":"R000057","series-title":"Nature Immunology","first-page":"264","article-title":"Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense","volume":"12","author":"Wei, M.","unstructured":"Wei, M., Shinkura, R., Doi, Y., Maruya, M., Fagarasan, S. and Honjo, T., 2011. Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense. Nature Immunology 12: 264-270."}],"container-title":["Beneficial Microbes"],"original-title":[],"link":[{"URL":"https:\/\/brill.com\/view\/journals\/bm\/aop\/article-10.1163-18762891-bja00120\/article-10.1163-18762891-bja00120.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/brill.com\/downloadpdf\/journals\/bm\/aop\/article-10.1163-18762891-bja00120\/article-10.1163-18762891-bja00120.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/brill.com\/downloadpdf\/journals\/bm\/aop\/article-10.1163-18762891-bja00120\/article-10.1163-18762891-bja00120.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:06:51Z","timestamp":1778728011000},"score":1,"resource":{"primary":{"URL":"https:\/\/brill.com\/view\/journals\/bm\/aop\/article-10.1163-18762891-bja00120\/article-10.1163-18762891-bja00120.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,11]]},"references-count":114,"URL":"https:\/\/doi.org\/10.1163\/18762891-bja00120","relation":{},"ISSN":["1876-2891"],"issn-type":[{"value":"1876-2891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,11]]}}}