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Of 473 patients admitted, 38% were HIV-1 seropositive, 4% were HIV-2 seropositive, and 14% reacted to both viruses. A total of 100 patients (21%) died, and deaths were twice as frequent in HIV-seropositive compared with HIV-negative patients. The pathology of 78 autopsies showed that the predominant cause of death in HIV-seropositive patients was disseminated tuberculosis (40%). Cancer was the cause of death in 64% of HIV-negative patients. Pneumocystosis was found in only 9% of HIV-seropositive autopsies. Since Pneumocystis carinii is an uncommon cause of death in this population, prophylaxis for P. carinii pneumonia is not warranted for HIV-infected patients in Africa. In contrast, research on chemoprophylaxis for tuberculosis is urgently required.<\/jats:p>","DOI":"10.1164\/ajrccm\/145.3.617","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T17:31:39Z","timestamp":1365096699000},"page":"617-620","source":"Crossref","is-referenced-by-count":105,"title":["<i>Pneumocystis carinii<\/i>\n                    Pneumonia: An Uncommon Cause of Death in African Patients with Acquired Immunodeficiency Syndrome"],"prefix":"10.1093","volume":"145","author":[{"given":"Y. 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