{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T09:08:27Z","timestamp":1774688907133,"version":"3.50.1"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[1995,8,1]],"date-time":"1995-08-01T00:00:00Z","timestamp":807235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>First, we evaluated the age profile and chest radiographic abnormalities in 146 patients from Dar-es-Salaam, Tanzania, with new-onset intrathoracic tuberculosis (pulmonary, pleural, or hilar\/mediastinal adenopathy), to identify features that were associated with human immunodeficiency virus (HIV) seropositivity or seronegativity; then, we combined these data with those from a companion investigation in Burundi to develop a simple scoring system to predict HIV serologic status. Using agreed-upon criteria and simplified reporting forms, initial chest radiographs were reviewed by three readers, first independently and then at a consensus conference. Of the 146 patients, 80 (55%) were HIV seropositive and 66 were seronegative. More seropositive than seronegative subjects were 31 to 40 yr old (p = 0.03). Because the radiographic characteristics of the two serologic groups were similar in Tanzania and Burundi, we combined the data for stepwise logistic regression that revealed four highly significant variables: age, small lesions, location, and lymphadenopathy. From these, we obtained an equation to calculate the probability that a given tuberculosis patients was HIV seropositive and then we derived a scoring system that in its simplest form (threshold) predicted serologic status correctly in 68.1% of patients; a graded scale was even more accurate in the high (89.1%) and low (82.6%) ranges. This scoring system should be useful when serologic testing is unavailable or refused.<\/jats:p>","DOI":"10.1164\/ajrccm.152.2.7633743","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T17:53:10Z","timestamp":1365097990000},"page":"786-793","source":"Crossref","is-referenced-by-count":20,"title":["Radiographic Abnormalities in Tuberculosis and Risk of Coexisting Human Immunodeficiency Virus Infection. Results From Dar-Es-Salaam, Tanzania, and Scoring System"],"prefix":"10.1093","volume":"152","author":[{"given":"N","family":"Mlika-Cabanne","sequence":"first","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Brauner","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Mugusi","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Grenier","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Daley","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Mbaga","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Larouz\u00e9","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J F","family":"Murray","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Unit\u00e9 13, H\u00f4pital Claude Bernard, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1995,8,1]]},"container-title":["American journal of respiratory and critical care medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/152\/2\/786\/67626798\/ajrccm_152_2_786.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/152\/2\/786\/67626798\/ajrccm_152_2_786.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T08:44:23Z","timestamp":1774687463000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/152\/2\/786\/8553745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,8,1]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1995,8,1]]},"published-print":{"date-parts":[[1995,8,1]]}},"URL":"https:\/\/doi.org\/10.1164\/ajrccm.152.2.7633743","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1995,8]]},"published":{"date-parts":[[1995,8,1]]}}}