{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:02:56Z","timestamp":1792504976645,"version":"4.5.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[1997,8,1]],"date-time":"1997-08-01T00:00:00Z","timestamp":870393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1997,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We evaluated pulmonary function abnormalities associated with the sleep apnea syndrome (SAS) in 170 habitual snorers without SAS (n = 62, apnea-hypopnea index [AHI] &amp;lt; 10 per hour of sleep), with moderately severe SAS (n = 56, 10 \u2264 AHI &amp;lt; 30) or with severe SAS (n = 52, AHI \u2265 30). The three groups were similar regarding obesity (BMI \u223c 30 kg \u00b7 m\u2212 \u00a02) and smoking history ( \u223c 20 pack-years). Pulmonary function was assessed by spirometry, forced oscillation mechanics, and gas exchange studies. Forced expiratory flows decreased as the SAS severity increased (p &amp;lt; 0.001, p &amp;lt; 0.02, and p &amp;lt; 0.05 for FEF50, FEV1, and FEV1\/VC, respectively). Multiple regression analysis showed that the correlation between FEV50 and the AHI persisted when smoking history was taken into account (p &amp;lt; 0.05), suggesting that SAS may be an independent risk factor for small airway disease. A highly significant correlation was found between specific respiratory conductance (sGrs) and the AHI (p &amp;lt; 0.0001). In a multiple regression analysis (p &amp;lt; 0.0001), variables that influenced sGrs were distal airway obstruction as assessed by FEV50 (p &amp;lt; 0.05), morphological upper airway abnormalities as assessed by cephalometric parameters (p &amp;lt; 0.02), and the AHI (p &amp;lt; 0.0005). SAS appears to be highly correlated to lower and upper airway obstruction, as demonstrated by a reduction in specific respiratory conductance, which adds to the increase in breathing load due to obesity. Zerah-Lancner F, Lofaso F, Coste A, Ricolfi F, Goldenberg F, Harf A. Pulmonary function in obese snorers with or without sleep apnea syndrome.<\/jats:p>","DOI":"10.1164\/ajrccm.156.2.9609015","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T13:25:36Z","timestamp":1365081936000},"page":"522-527","source":"Crossref","is-referenced-by-count":63,"title":["Pulmonary Function in Obese Snorers with or without Sleep Apnea Syndrome"],"prefix":"10.1093","volume":"156","author":[{"given":"FRAN\u00c7OISE","family":"ZERAH-LANCNER","sequence":"first","affiliation":[{"name":"Services de Physiologie-Explorations Fonctionnelles, d'Otorhinolaryngologie et de Neuroradiologie, and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 296, H\u00f4pital Henri Mondor, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FR\u00c9D\u00c9RIC","family":"LOFASO","sequence":"additional","affiliation":[{"name":"Services de Physiologie-Explorations Fonctionnelles, d'Otorhinolaryngologie et de Neuroradiologie, and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 296, H\u00f4pital Henri Mondor, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANDR\u00c9","family":"COSTE","sequence":"additional","affiliation":[{"name":"Services de Physiologie-Explorations Fonctionnelles, d'Otorhinolaryngologie et de Neuroradiologie, and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 296, H\u00f4pital Henri Mondor, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FR\u00c9D\u00c9RIC","family":"RICOLFI","sequence":"additional","affiliation":[{"name":"Services de Physiologie-Explorations Fonctionnelles, d'Otorhinolaryngologie et de Neuroradiologie, and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 296, H\u00f4pital Henri Mondor, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FRAN\u00c7OISE","family":"GOLDENBERG","sequence":"additional","affiliation":[{"name":"Services de Physiologie-Explorations Fonctionnelles, d'Otorhinolaryngologie et de Neuroradiologie, and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 296, H\u00f4pital Henri Mondor, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ALAIN","family":"HARF","sequence":"additional","affiliation":[{"name":"Services de Physiologie-Explorations Fonctionnelles, d'Otorhinolaryngologie et de Neuroradiologie, and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, INSERM U 296, H\u00f4pital Henri Mondor, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1997,8,1]]},"reference":[{"key":"2026032709240281000_B1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1164\/ajrccm.151.1.7812577","article-title":"Association of chronic obstructive pulmonary disease and sleep apnea syndrome.","volume":"151","author":"Chaouat","year":"1995","journal-title":"Am. 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