{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T14:11:24Z","timestamp":1774620684619,"version":"3.50.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[1998,12,1]],"date-time":"1998-12-01T00:00:00Z","timestamp":912470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>To estimate the prevalence of respiratory symptoms, bronchial hyperresponsiveness, smoking, and atopy in a population of Australians of Aboriginal descent (AAD), to determine the association of these and other factors with lung function, and to compare levels of lung function of AAD with Australians of European descent (AED) according to age and height, and to explore reasons for their differences, we conducted a study of 96 male (41 of whom were under 18 yr of age) and 111 female (48 of whom were under 18 yr of age) AAD living in a single remote tropical community in 1993. This population provided data on age, height, and lung function. A modified British Medical Research Council (MRC) questionnaire on respiratory symptoms and smoking was administered. FEV1, FVC, height, age, and bronchial responsiveness to inhaled methacholine were measured. Atopic status was assessed by skin prick tests for eight common allergens. Age- and sex-adjusted lung function was similar to that of other AAD groups and lower than in AED. For children, lung function increased less with increasing height in AAD than in AED. Lung function was reduced in adult AAD as compared with adult AED, although it was not possible to determine statistically whether lung function started to decline at an earlier age or declined faster with increasing age in AAD. A history of asthma, smoking, dyspnea, cough, or sputum production; atopic status; and increased bronchial responsiveness were all associated with lower levels of lung function. Differences in lung function between AAD and AED appear to be determined by characteristics that may be inherited, as well as by adverse external influences.<\/jats:p>","DOI":"10.1164\/ajrccm.158.6.9702068","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T13:51:12Z","timestamp":1365083472000},"page":"1724-1729","source":"Crossref","is-referenced-by-count":35,"title":["Respiratory Symptoms and Lung Function in Aborigines from Tropical Western Australia"],"prefix":"10.1093","volume":"158","author":[{"given":"PETER R.","family":"BREMNER","sequence":"first","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NICHOLAS H.","family":"de KLERK","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GERARD F.","family":"RYAN","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALAN L.","family":"JAMES","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL","family":"MUSK","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CATHERINE","family":"MURRAY","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PETER N.","family":"LE S\u00d6UEF","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SALLY","family":"YOUNG","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RANDOLPH","family":"SPARGO","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"WILLIAM MUSK","sequence":"additional","affiliation":[{"name":"Departments of Respiratory Medicine and Pulmonary Physiology, Sir Charles Gairdner Hospital; Departments of Public Health and Paediatrics, University of Western Australia, Princess Margaret Hospital for Children; and Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1998,12,1]]},"reference":[{"key":"2026032709055811800_B1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.5694\/j.1326-5377.1976.tb76699.x","article-title":"The physical health of Aboriginal adults in Bourke, New South Wales.","volume":"1","author":"Kamien","year":"1976","journal-title":"Med. 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