{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T23:22:33Z","timestamp":1789946553274,"version":"4.0.1"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[1999,5,1]],"date-time":"1999-05-01T00:00:00Z","timestamp":925516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The mechanical effect of musculus uvulae (MU) contraction on in vitro uvular shortening and\/or displacement was measured in 15 patients with a sleep apnea hypopnea syndrome (SAHS) and in 8 snorers. Using freshly resected uvular tissues, passive and active uvular tissue-specific elastance and shortening were determined during stimulation of MU. No difference was found in maximum tetanic tension measured on uvular tissue between the two groups (47.2 \u00b1 14.8 g in SAHS and 39.1 \u00b1 16.5 g in snorers). Passive uvular-specific elastance was significantly less in snorers (0.36 \u00b1 0.27 g\/% Lo) compared with patients with SAHS (0.84 \u00b1 0.39 g\/% Lo) (p = 0.006). There was a negative correlation between uvular shortening and passive uvular specific elastance (r = 0.69, p = 0.05). Maximal tetanic tension developed by isolated MU was higher in SAHS than in snorers (45.8 \u00b1 23.1 and 30.0 \u00b1 8.3 g, respectively, p = 0.04). A strong positive relationship was found between the apnea index and specific uvular elastance (r = 0.55, p = 0.007). We conclude that there is a significant difference between the uvular tissue elastance of SAHS and snorers, and that this difference influences the mechanical efficiency of MU contraction.<\/jats:p>","DOI":"10.1164\/ajrccm.159.5.9804124","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T13:59:17Z","timestamp":1365083957000},"page":"1551-1555","source":"Crossref","is-referenced-by-count":38,"title":["Dysfunctional Mechanical Coupling of Upper Airway Tissues in Sleep Apnea Syndrome"],"prefix":"10.1093","volume":"159","author":[{"given":"FR\u00c9D\u00c9RIC","family":"S\u00c9RI\u00c8S","sequence":"first","affiliation":[{"name":"Unit\u00e9 de Recherche, Centre de Pneumologie de l'H\u00f4pital Laval; and Laboratoire de Neurosciences and Ear, Nose, and Throat Department, Centre Hospitalier de l'Universit\u00e9 Laval, Universit\u00e9 Laval, Ste. Foy, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CLAUDE","family":"C\u00d4T\u00c9","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Recherche, Centre de Pneumologie de l'H\u00f4pital Laval; and Laboratoire de Neurosciences and Ear, Nose, and Throat Department, Centre Hospitalier de l'Universit\u00e9 Laval, Universit\u00e9 Laval, Ste. Foy, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SYLVAIN","family":"ST. PIERRE","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Recherche, Centre de Pneumologie de l'H\u00f4pital Laval; and Laboratoire de Neurosciences and Ear, Nose, and Throat Department, Centre Hospitalier de l'Universit\u00e9 Laval, Universit\u00e9 Laval, Ste. Foy, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1999,5,1]]},"reference":[{"key":"2026032708543486700_B1","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The occurence of sleep-related breathing among middle-aged adults.","volume":"328","author":"Young","year":"1993","journal-title":"N. Engl. J. 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