{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:55:48Z","timestamp":1793397348904,"version":"4.5.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>To investigate the prevalence and behavior of sleep-related breathing disorders (SRBDs) associated with a first-ever stroke or transient ischemic attack (TIA), we prospectively studied 161 consecutive patients admitted to our stroke unit. Complete neurological assessment was performed to determine parenchymatous and vascular localization of the neurological lesion. Stroke subtype was categorized as TIA, ischemic (IS), or hemorrhagic (HS). A portable respiratory recording (PRR) study was performed within 48\u201372 h after admission (acute phase), and subsequently after 3 mo (stable phase). During the acute phase, 116 patients (71.4%) had an apnea\u2013hypopnea index (AHI) &amp;gt; 10 events\/h and 45 (28%) had an AHI &amp;gt; 30. No relationships were found between sleep-related respiratory events and the topographical parenchymatous location of the neurological lesion or vascular involvement. Cheyne\u2013Stokes breathing (CSB) was observed in 42 cases (26.1%). There were no significant differences in SRBD according to the stroke subtype except for the central apnea index (CAI). During the stable phase a second PRR was performed in 86 patients: 53 of 86 had an AHI &amp;gt; 10 and 17 of 86 had an AHI &amp;gt; 30. The AHI and CAI were significantly lower than those in the acute phase (16.9 \u00b1 13.8 versus 22.4 \u00b1 17.3 and 3.3 \u00b1 7.6 versus 6.2 \u00b1 10.2, respectively) (p &amp;lt; 0.05) while the obstructive apnea index (OAI) remained unchanged. CSB was observed in 6 of 86 patients. The prevalence of SRBD in patients with first-ever stroke or TIA is higher than expected from the available epidemiological data in our country. No correlation was found between neurological location and the presence or type of SRBD. Obstructive events seem to be a condition prior to the neurological disease whereas central events and CSB could be its consequence. Parra O, Arboix A, Bechich S, Garc\u00eda-Eroles L, Montserrat JM, L\u00f3pez JA, Ballester E, Guerra JM, Sope\u00f1a JJ. Time course of sleep-related breathing disorders in first-ever stroke or transient ischemic attack.<\/jats:p>","DOI":"10.1164\/ajrccm.161.2.9903139","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T14:12:05Z","timestamp":1365084725000},"page":"375-380","source":"Crossref","is-referenced-by-count":447,"title":["Time Course of Sleep-related Breathing Disorders in First-Ever Stroke or Transient Ischemic Attack"],"prefix":"10.1093","volume":"161","author":[{"given":"OLGA","family":"PARRA","sequence":"first","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ADRI\u00c1","family":"ARBOIX","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SIRAJ","family":"BECHICH","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LUIS","family":"GARC\u00cdA-EROLES","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOSEP M.","family":"MONTSERRAT","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOSEP ANTONI","family":"L\u00d3PEZ","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EUGENI","family":"BALLESTER","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOSEP M.","family":"GUERRA","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JUAN JOS\u00c9","family":"SOPE\u00d1A","sequence":"additional","affiliation":[{"name":"Servei de Pneumologia and Neurology, Hospital del Sagrat Cor, Barcelona, Spain; and Institut Cl\u00ednic de Pneumologia i Cirurgia Tor\u00e0cica (ICPCT), Hospital Cl\u00ednic, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2000,2,1]]},"reference":[{"key":"2026032708361511600_B1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0140-6736(90)91799-G","article-title":"Association of sleep apnea with myocardial infarction in men.","volume":"336","author":"Hung","year":"1990","journal-title":"Lancet"},{"key":"2026032708361511600_B2","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1136\/thx.44.12.984","article-title":"Sleep apnea and systemic hypertension.","volume":"44","author":"Stradling","year":"1989","journal-title":"Thorax"},{"key":"2026032708361511600_B3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1378\/chest.94.1.9","article-title":"Mortality and apnea index in obstructive sleep apnea: experience in 385 male patients.","volume":"94","author":"He","year":"1988","journal-title":"Chest"},{"key":"2026032708361511600_B4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1378\/chest.97.1.27","article-title":"Daytime sleepiness and vascular morbidity at seven-year follow-up in obstructive sleep apnea patients.","volume":"97","author":"Partinen","year":"1990","journal-title":"Chest"},{"key":"2026032708361511600_B5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1136\/bmj.294.6563.16","article-title":"Snoring as a risk factor for ischaemic heart disease and stroke in men.","volume":"294","author":"Koskenvuo","year":"1987","journal-title":"Br. 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