{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:06:16Z","timestamp":1791317176121,"version":"4.3.1"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The aim of this study was to assess the influence of some risk factors for onset and remission of allergic rhinitis and asthma in Swedish adults. A random sample of 1,370 subjects, age 20 to 44 yr was investigated by means of postal questionnaires in 1990 and 1993. Skin prick tests were conducted in 1991\u20131992. The association between risk factors and onset or remission of allergic rhinitis and asthma was estimated using multivariate logistic regression analysis. Onset of allergic rhinitis was associated with sensitization to birch (odds ratio [OR] = 6.5), Parietaria (OR = 7.4); and pets (OR = 3.0) and with female sex (OR = 1.9). Onset of asthma was associated with allergic rhinitis (OR = 4.9), sensitization to pets (OR = 2.4); and with smoking (OR = 3.0). Onset of asthma was strongly associated with allergic rhinitis among atopics (OR = 5.7), but onset of asthma and rhinitis also tended to be related among nonatopics (OR = 3.5). A strong association between smoking and onset of asthma was found among nonatopics (OR = 5.7). In conclusion, sensitization to pollens and pets were risk factors for onset of allergic rhinitis, whereas allergic rhinitis, sensitization to pets, and smoking were risk factors for onset of asthma.<\/jats:p>","DOI":"10.1164\/ajrccm.162.3.9912030","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T14:23:40Z","timestamp":1365085420000},"page":"920-924","source":"Crossref","is-referenced-by-count":212,"title":["Onset and Remission of Allergic Rhinitis and Asthma and the Relationship with Atopic Sensitization and Smoking"],"prefix":"10.1093","volume":"162","author":[{"given":"PETER P.","family":"PLASCHKE","sequence":"first","affiliation":[{"name":"Amager Hospital, Copenhagen University Hospitals, Denmark, and Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, G\u00f6teborg, Sweden; Department of Medical Sciences, Respiratory Medicine and Allergology and Asthma Research Center, Akademiska Sjukhuset, Uppsala, Sweden; Department of Pulmonary Medicine and Allergology, University Hospital of Northern Sweden, Ume\u00e5, Sweden; and Occupational Medicine, Department of Public Health and Clinical Medicine, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHRISTER","family":"JANSON","sequence":"additional","affiliation":[{"name":"Amager Hospital, Copenhagen University Hospitals, Denmark, and Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, G\u00f6teborg, Sweden; Department of Medical Sciences, Respiratory Medicine and Allergology and Asthma Research Center, Akademiska Sjukhuset, Uppsala, Sweden; Department of Pulmonary Medicine and Allergology, University Hospital of Northern Sweden, Ume\u00e5, Sweden; and Occupational Medicine, Department of Public Health and Clinical Medicine, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EVA","family":"NORRMAN","sequence":"additional","affiliation":[{"name":"Amager Hospital, Copenhagen University Hospitals, Denmark, and Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, G\u00f6teborg, Sweden; Department of Medical Sciences, Respiratory Medicine and Allergology and Asthma Research Center, Akademiska Sjukhuset, Uppsala, Sweden; Department of Pulmonary Medicine and Allergology, University Hospital of Northern Sweden, Ume\u00e5, Sweden; and Occupational Medicine, Department of Public Health and Clinical Medicine, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EYTHOR","family":"BJ\u00d6RNSSON","sequence":"additional","affiliation":[{"name":"Amager Hospital, Copenhagen University Hospitals, Denmark, and Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, G\u00f6teborg, Sweden; Department of Medical Sciences, Respiratory Medicine and Allergology and Asthma Research Center, Akademiska Sjukhuset, Uppsala, Sweden; Department of Pulmonary Medicine and Allergology, University Hospital of Northern Sweden, Ume\u00e5, Sweden; and Occupational Medicine, Department of Public Health and Clinical Medicine, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SUSANNE","family":"ELLBJ\u00c4R","sequence":"additional","affiliation":[{"name":"Amager Hospital, Copenhagen University Hospitals, Denmark, and Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, G\u00f6teborg, Sweden; Department of Medical Sciences, Respiratory Medicine and Allergology and Asthma Research Center, Akademiska Sjukhuset, Uppsala, Sweden; Department of Pulmonary Medicine and Allergology, University Hospital of Northern Sweden, Ume\u00e5, Sweden; and Occupational Medicine, Department of Public Health and Clinical Medicine, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BENGT","family":"J\u00c4RVHOLM","sequence":"additional","affiliation":[{"name":"Amager Hospital, Copenhagen University Hospitals, Denmark, and Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, G\u00f6teborg, Sweden; Department of Medical Sciences, Respiratory Medicine and Allergology and Asthma Research Center, Akademiska Sjukhuset, Uppsala, Sweden; Department of Pulmonary Medicine and Allergology, University Hospital of Northern Sweden, Ume\u00e5, Sweden; and Occupational Medicine, Department of Public Health and Clinical Medicine, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2000,9,1]]},"reference":[{"key":"2026032708271667400_B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1183\/09031936.93.05010012","article-title":"Changes in chronic respiratory symptoms in two populations of adults studied longitudinally over 13 years.","volume":"5","author":"Krzyzanowski","year":"1992","journal-title":"Eur Respir. J."},{"key":"2026032708271667400_B2","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/j.1365-2222.1995.tb00023.x","article-title":"Increase of asthma, allergic rhinitis and eczema in Swedish schoolchildren between 1979 and 1991.","volume":"25","author":"\u212bberg","year":"1995","journal-title":"Clin. Exp. Allergy"},{"key":"2026032708271667400_B3","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1056\/NEJM198902023200502","article-title":"Association of asthma with serum IgE levels and skin test reactivity to allergens.","volume":"320","author":"Burrows","year":"1989","journal-title":"N. Engl. J. Med."},{"key":"2026032708271667400_B4","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1183\/09031936.97.10112490","article-title":"Risk factors for asthma in young adults.","volume":"10","author":"Sunyer","year":"1997","journal-title":"Eur. Respir. J."},{"key":"2026032708271667400_B5","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0091-6749(99)70114-4","article-title":"Association of skin test reactivity, specific IgE and total IgE with asthma and bronchial hyper-responsiveness in Swedish adults: pets and not mites are the most important allergens.","volume":"103","author":"Plaschke","year":"1999","journal-title":"J. Allergy Clin. Immunol."},{"key":"2026032708271667400_B6"},{"key":"2026032708271667400_B7","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1183\/09031936.94.07122146","article-title":"Symptoms related to asthma and chronic bronchitis in three areas of Sweden.","volume":"7","author":"Bj\u00f6rnsson","year":"1994","journal-title":"Eur. Respir. J."},{"key":"2026032708271667400_B8","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1398-9995.1996.tb04652.x","article-title":"Skin prick test and specific IgE in adults from three different areas of Sweden.","volume":"51","author":"Plaschke","year":"1996","journal-title":"Allergy"},{"key":"2026032708271667400_B9"},{"key":"2026032708271667400_B10","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1378\/chest.91.6_Supplement.79S","article-title":"Developing a new questionnaire for measuring the prevalence and distribution of asthma.","volume":"91 (Suppl.)","author":"Burney","year":"1987","journal-title":"Chest"},{"key":"2026032708271667400_B11","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1183\/09031936.93.02090940","article-title":"Validity and repeatability of the IUATLD (1984) bronchial symptoms questionnaire: an international comparison.","volume":"2","author":"Burney","year":"1989","journal-title":"Eur. Respir. J."},{"key":"2026032708271667400_B12"},{"key":"2026032708271667400_B13"},{"key":"2026032708271667400_B14","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0091-6749(97)81050-0","article-title":"Major cat and dog allergens share IgE epitopes.","volume":"99","author":"Spitzauer","year":"1997","journal-title":"J. Allergy Clin. Immunol."},{"key":"2026032708271667400_B15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.2500\/108854194778816634","article-title":"Long term risk factors for developing asthma and allergic rhinitis: a 23 year follow-up study of college students.","volume":"15","author":"Settipane","year":"1994","journal-title":"Allergy Proc."},{"key":"2026032708271667400_B16","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0091-6749(97)70127-1","article-title":"Allergic rhinitis and asthma: how important is the link?","volume":"99","author":"Corren","year":"1997","journal-title":"J. Allergy Clin. Immunol."},{"key":"2026032708271667400_B17","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0091-6749(99)70370-2","article-title":"Perennial rhinitis: an independent risk factor for asthma in nonatopic subjects. Results from the European Community Respiratory Health Survey.","volume":"104","author":"Leynaert","year":"1999","journal-title":"J. Allergy Clin. Immunol."},{"key":"2026032708271667400_B18","first-page":"33","article-title":"Hypersensitivity to common indoor aeroallergens in asthmatic patients.","volume":"71","author":"Lin","year":"1993","journal-title":"Ann. Allergy"},{"key":"2026032708271667400_B19","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1164\/ajrccm.156.1.9608072","article-title":"Sensitization to cat allergen is associated with asthma in older men and predicts new-onset airway hyperresponsiveness.","volume":"156","author":"Augusto","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"2026032708271667400_B20","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1399-3038.1998.tb00296.x","article-title":"Concentrations of cat (Fel d1), dog (Can f1) and mite (Der f1 and Der p1) allergens in the clothing and school environment of Swedish schoolchildren with and without pets at home.","volume":"9","author":"Berge","year":"1998","journal-title":"Pediatr. Allergy Immunol."},{"key":"2026032708271667400_B21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1399-3038.1998.tb00297.x","article-title":"Cat and dog allergen in mattresses and textile covered floors of homes which do or do not have pets, either in the past or currently.","volume":"9","author":"Egmar","year":"1998","journal-title":"Pediatr. Allergy Immunol."},{"key":"2026032708271667400_B22","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0091-6749(96)80064-9","article-title":"Cat antigen in homes with and without cats may induce allergic symptoms.","volume":"97","author":"Bollinger","year":"1996","journal-title":"J. Allergy Clin. Immunol."},{"key":"2026032708271667400_B23"},{"key":"2026032708271667400_B24","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1136\/adc.62.4.338","article-title":"Parental smoking, breast feeding and respiratory infections in development of allergic diseases.","volume":"62","author":"Cogswell","year":"1987","journal-title":"Arch. Dis. Child."},{"key":"2026032708271667400_B25"},{"key":"2026032708271667400_B26","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1164\/arrd.1977.116.3.403","article-title":"Smoking, socioeconomic status, and chronic respiratory disease.","volume":"116","author":"Higgins","year":"1977","journal-title":"Am. Rev. Respir. Dis."},{"key":"2026032708271667400_B27","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1136\/thx.43.7.534","article-title":"Prospective study of asthma in relation to smoking habits among 14,729 adults.","volume":"43","author":"Vesterinen","year":"1988","journal-title":"Thorax"},{"key":"2026032708271667400_B28","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1378\/chest.108.6.1557","article-title":"Cigarette smoking and incidence of chronic bronchitis and asthma in women.","volume":"108","author":"Troisi","year":"1995","journal-title":"Chest"},{"key":"2026032708271667400_B29","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1136\/thx.50.3.260","article-title":"Incidence of asthma in Swedish teenagers\u2014relation to gender and smoking habits.","volume":"50","author":"Larsson","year":"1994","journal-title":"Thorax"},{"key":"2026032708271667400_B30","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1398-9995.1998.tb03770.x","article-title":"Prevalence and incidence of asthma and rhinoconjunctivitis in Swedish teenagers.","volume":"53","author":"Norrman","year":"1998","journal-title":"Allergy"},{"key":"2026032708271667400_B31","first-page":"1195","article-title":"Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort.","volume":"312","author":"Strachan","year":"1996","journal-title":"B.M.J."},{"key":"2026032708271667400_B32","doi-asserted-by":"crossref","first-page":"219","DOI":"10.3109\/02770909709068192","article-title":"Smoking and asthma among 23-year-olds.","volume":"34","author":"Kaplan","year":"1997","journal-title":"J. Asthma"},{"key":"2026032708271667400_B33","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/00001648-199509000-00007","article-title":"An epidemiologic study of bronchial asthma and smoking.","volume":"6","author":"Flodin","year":"1995","journal-title":"Epidemiology"}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/162\/3\/920\/67545072\/ajrccm_162_3_920.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/162\/3\/920\/67545072\/ajrccm_162_3_920.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T12:27:24Z","timestamp":1774614444000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/162\/3\/920\/8540772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9,1]]},"references-count":33,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2000,9,1]]},"published-print":{"date-parts":[[2000,9,1]]}},"URL":"https:\/\/doi.org\/10.1164\/ajrccm.162.3.9912030","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2000,9]]},"published":{"date-parts":[[2000,9,1]]}}}