{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T13:14:29Z","timestamp":1774617269391,"version":"3.50.1"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2000,10,1]],"date-time":"2000-10-01T00:00:00Z","timestamp":970358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In this study, we characterized patients who developed respiratory failure postoperatively after lung volume reduction surgery (LVRS). We retrospectively reviewed the records of 72 patients who underwent LVRS from February 1995 to February 1998, examining perioperative variables and complications. Twenty-one patients (29%) developed postoperative respiratory failure, five due to hypoxemia, nine due to hypercapnia, and seven secondary to hemodynamic instability. The hospital mortality was 33% among patients who developed respiratory failure. No preoperative clinical or physiologic variable (including percent ideal body weight, serum albumin, prednisone use, lung function, maximal O2 uptake on exercise testing, 6-min walk distance, and hemodynamic parameters) was predictive of postoperative respiratory failure. Patients who developed respiratory failure were older (63 \u00b1 7 versus 57 \u00b1 8 yr, p = 0.01), had longer anesthesia time (188 \u00b1 96 versus 127 \u00b1 56 min, p = 0.001), had a higher incidence of coronary artery disease (40% versus 10%, p = 0.001) and performance of concomitant surgical procedures during the LVRS operation (40% versus 2%, p &amp;lt; 0.001) compared with those without respiratory failure. All patients who underwent simultaneous surgery, which were mostly for cardiac disease, developed respiratory failure. Risk factor analysis confirmed that older patients and those undergoing cardiac surgery combined with LVRS are at increased risk for postoperative respiratory failure.<\/jats:p>","DOI":"10.1164\/ajrccm.162.4.9912074","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T14:28:59Z","timestamp":1365085739000},"page":"1292-1296","source":"Crossref","is-referenced-by-count":6,"title":["Acute Respiratory Failure after Lung Volume Reduction Surgery"],"prefix":"10.1093","volume":"162","author":[{"given":"WISSAM","family":"CHATILA","sequence":"first","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, and Cardiothoracic Division, Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SATOSHI","family":"FURUKAWA","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, and Cardiothoracic Division, Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GERARD J.","family":"CRINER","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, and Cardiothoracic Division, Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2000,10,1]]},"reference":[{"key":"2026032708300895300_B1","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0022-5223(96)70147-2","article-title":"Results of 150 consecutive bilateral lung volume reduction procedures in patients with severe emphysema.","volume":"112","author":"Cooper","year":"1996","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"2026032708300895300_B2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0022-5223(96)70440-3","article-title":"A randomized, prospective trial of stapled lung reduction versus laser bullectomy for diffuse emphysema.","volume":"111","author":"Mckenna","year":"1996","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"2026032708300895300_B3","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0022-5223(96)70439-7","article-title":"Unilateral thoracoscopic surgical approach for diffuse emphysema.","volume":"111","author":"Keenan","year":"1996","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"2026032708300895300_B4","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0022-5223(96)70086-7","article-title":"Bilateral volume reduction surgery for diffuse pulmonary emphysema by video-assisted thoracoscopy.","volume":"112","author":"Bingisser","year":"1996","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"2026032708300895300_B5","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/S0003-4975(96)00886-7","article-title":"Extended indications for lung volume reduction surgery in advanced emphysema.","volume":"62","author":"Argenziano","year":"1996","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B6","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1378\/chest.115.1.75","article-title":"Improvements in lung function, exercise, and quality of life in hypercapnic COPD patients after lung volume reduction surgery.","volume":"115","author":"O'Brien","year":"1999","journal-title":"Chest"},{"key":"2026032708300895300_B7","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S0022-5223(96)70438-5","article-title":"Comparison of early functional results after volume reduction surgery or lung transplantation for chronic obstructive lung disease.","volume":"111","author":"Gaissert","year":"1996","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"2026032708300895300_B8","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1164\/ajrccm.160.6.9902117","article-title":"Prospective randomized trial comparing bilateral lung volume reduction surgery to pulmonary rehabilitation in severe COPD.","volume":"160","author":"Criner","year":"1999","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"2026032708300895300_B9","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0003-4975(98)00115-5","article-title":"Bilateral lung volume reduction surgery via median sternotomy for severe pulmonary emphysema.","volume":"65","author":"Date","year":"1998","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B10","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/0003-4975(95)00485-4","article-title":"Thoracoscopic laser pneumoplasty in the treatment of diffuse bullous emphysema.","volume":"60","author":"Wakabayashi","year":"1995","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B11","first-page":"934","article-title":"Video-thoracic surgery for treatment of end-stage bullous emphysema and chronic obstructive pulmonary disease.","volume":"61","author":"Eugene","year":"1995","journal-title":"Am. Surg."},{"key":"2026032708300895300_B12","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/00000542-199301000-00008","article-title":"Anesthesia for thoracoscopic laser ablation of bullous emphysema.","volume":"78","author":"Barker","year":"1993","journal-title":"Anesthesiology"},{"key":"2026032708300895300_B13","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0022-5223(98)70437-4","article-title":"Effect of lung volume reduction on lung transplant timing and selection for chronic obstructive lung disease.","volume":"115","author":"Bavaria","year":"1998","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"2026032708300895300_B14","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1378\/chest.110.1.28","article-title":"Lung volume reduction surgery in patients with severe diffuse emphysema.","volume":"110","author":"Rou\u00e9","year":"1996","journal-title":"Chest"},{"key":"2026032708300895300_B15","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/00000658-199605000-00008","article-title":"Lung volume reduction surgery: case selection, operative technique, and clinical results.","volume":"223","author":"Daniel","year":"1996","journal-title":"Ann. Surg."},{"key":"2026032708300895300_B16","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/0003-4975(96)00124-5","article-title":"Lung volume reduction surgery: lessons learned.","volume":"61","author":"Miller","year":"1996","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B17","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1378\/chest.111.3.550","article-title":"Preoperative morbidity and in COPD patients undergoing bilateral lung volume reduction surgery.","volume":"111","author":"Szekely","year":"1997","journal-title":"Chest"},{"key":"2026032708300895300_B18","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1378\/chest.110.6.1399","article-title":"Bilateral lung volume reduction surgery for advanced emphysema: a comparison of median sternotomy and thoracoscopic approaches.","volume":"110","author":"Kotloff","year":"1996","journal-title":"Chest"},{"key":"2026032708300895300_B19","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/0003-4975(96)00067-7","article-title":"Unilateral video-assisted thoracic surgical lung reduction.","volume":"61","author":"Naunheim","year":"1996","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B20","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1016\/0003-4975(93)91078-2","article-title":"VATSargon beam coagulator treatment of diffuse end-stage bilateral bullous disease of the lung.","volume":"55","author":"Lewis","year":"1993","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B21","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1161\/01.CIR.91.3.912","article-title":"AHA Committee guidelines for clinical exercise testing laboratories.","volume":"91","author":"Pina","year":"1995","journal-title":"Circ."},{"key":"2026032708300895300_B22","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1378\/chest.112.1.122","article-title":"Coronary artery disease in patients undergoing lung volume reduction surgery for emphysema.","volume":"112","author":"Thurnheer","year":"1997","journal-title":"Chest"},{"key":"2026032708300895300_B23","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/0003-4975(96)00206-8","article-title":"Results of combined pulmonary resection and cardiac operation.","volume":"62","author":"Rao","year":"1996","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B24","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0003-4975(92)91387-O","article-title":"Concomitant cardiac and pulmonary operation: the role of cardiopulmonary bypass.","volume":"54","author":"Ulicny","year":"1992","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B25","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1016\/S0003-4975(98)00787-5","article-title":"Combined lung volume reduction surgery and mitral valve reconstruction.","volume":"66","author":"Whyte","year":"1998","journal-title":"Ann. Thorac. Surg"},{"key":"2026032708300895300_B26","first-page":"509","article-title":"Combined lung volume reduction surgery and thoracic aortic aneurysm resection.","volume":"39","author":"Zannini","year":"1998","journal-title":"J. Cardiovasc. Surg."}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/162\/4\/1292\/67543723\/ajrccm_162_4_1292.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/162\/4\/1292\/67543723\/ajrccm_162_4_1292.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T12:30:18Z","timestamp":1774614618000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/162\/4\/1292\/8540906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10,1]]},"references-count":26,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2000,10,1]]},"published-print":{"date-parts":[[2000,10,1]]}},"URL":"https:\/\/doi.org\/10.1164\/ajrccm.162.4.9912074","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2000,10]]},"published":{"date-parts":[[2000,10,1]]}}}