{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T13:19:31Z","timestamp":1774617571612,"version":"3.50.1"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Many asbestos-exposed individuals complain of chest pain for which there is no clear explanation. To determine whether chest pain is associated with the presence of benign pleural or parenchymal disease on chest radiograph, we studied 1,280 subjects undergoing surveillance because of prior asbestos exposure at Wittenoom, Western Australia. All subjects completed the Rose questionnaire on chest pain and this revealed 556 subjects (43%) who experienced some chest pain. A posterior\u2013anterior chest radiograph was performed at the same clinic visit and was subsequently graded independently by two experienced readers for diffuse parenchymal disease and pleural disease. Logistic regression models adjusted for sex, age, and cumulative asbestos exposure indicated that the presence of chest pain was significantly associated with the presence of both benign pleural disease and diffuse parenchymal disease. Further analysis after stratification of chest pain into nonanginal and anginal pain showed that there was a significant association between anginal pain and the presence of pleural and parenchymal asbestos-induced radiologic abnormalities and an association of nonanginal pain with parenchymal disease. We conclude that radiographic evidence of either parenchymal or pleural disease in subjects exposed to asbestos is significantly related to the presence of chest pain, particularly anginal pain.<\/jats:p>","DOI":"10.1164\/ajrccm.162.5.9912012","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T14:25:08Z","timestamp":1365085508000},"page":"1807-1811","source":"Crossref","is-referenced-by-count":28,"title":["Chest Pain in Asbestos-exposed Individuals with Benign Pleural and Parenchymal Disease"],"prefix":"10.1093","volume":"162","author":[{"given":"SUTAPA","family":"MUKHERJEE","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia; Departments of Public Health, Paediatrics, and Medicine, University of Western Australia, Nedlands, Australia; TVW Telethon Institute for Child Health Research, Perth; and Perth Chest Clinic, Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NICHOLAS","family":"de KLERK","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia; Departments of Public Health, Paediatrics, and Medicine, University of Western Australia, Nedlands, Australia; TVW Telethon Institute for Child Health Research, Perth; and Perth Chest Clinic, Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LYLE J.","family":"PALMER","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia; Departments of Public Health, Paediatrics, and Medicine, University of Western Australia, Nedlands, Australia; TVW Telethon Institute for Child Health Research, Perth; and Perth Chest Clinic, Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. J.","family":"OLSEN","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia; Departments of Public Health, Paediatrics, and Medicine, University of Western Australia, Nedlands, Australia; TVW Telethon Institute for Child Health Research, Perth; and Perth Chest Clinic, Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. C.","family":"PANG","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia; Departments of Public Health, Paediatrics, and Medicine, University of Western Australia, Nedlands, Australia; TVW Telethon Institute for Child Health Research, Perth; and Perth Chest Clinic, Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"WILLIAM MUSK","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia; Departments of Public Health, Paediatrics, and Medicine, University of Western Australia, Nedlands, Australia; TVW Telethon Institute for Child Health Research, Perth; and Perth Chest Clinic, Health Department of Western Australia, Perth, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2000,11,1]]},"reference":[{"key":"2026032708335506500_B1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/0037-198X(92)90053-5","article-title":"Asbestos-related chest diseases: plain radiographic findings.","volume":"27","author":"Miller","year":"1992","journal-title":"Semin Roentgenol"},{"key":"2026032708335506500_B2","first-page":"133","article-title":"Radiographic evaluation of asbestos-related chest disorders.","volume":"21","author":"Gefter","year":"1984","journal-title":"Crit Rev Diagn Imaging"},{"key":"2026032708335506500_B3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00005382-198810000-00005","article-title":"Issues and controversies in the plain-film diagnosis of asbestos-related disorders in the chest.","volume":"3","author":"Gefter","year":"1988","journal-title":"J Thorac Imaging"},{"key":"2026032708335506500_B4","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1097\/00043764-199606000-00011","article-title":"Radiographic small lung opacities and pleural abnormalities in relation to smoking, urbanization status, and occupational asbestos exposure in Finland.","volume":"38","author":"Zitting","year":"1996","journal-title":"J Occup Environ Med"},{"key":"2026032708335506500_B5"},{"key":"2026032708335506500_B6","first-page":"902","article-title":"Radiographic abnormalities and mortality in subjects with exposure to crocidolite.","volume":"50","author":"de Klerk","year":"1993","journal-title":"Br J Ind Med"},{"key":"2026032708335506500_B7","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1378\/chest.101.3.684","article-title":"Pleural determinants of restrictive lung function and respiratory symptoms in an asbestos-exposed population.","volume":"101","author":"Broderick","year":"1992","journal-title":"Chest"},{"key":"2026032708335506500_B8"},{"key":"2026032708335506500_B9","first-page":"621","article-title":"Pleural thickening: its significance and relationship to asbestos dust exposure.","volume":"126","author":"Albelda","year":"1982","journal-title":"Am Rev Respir Dis"},{"key":"2026032708335506500_B10","first-page":"345","article-title":"Do pleural plaques produce symptoms? 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