{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T07:19:19Z","timestamp":1774941559660,"version":"3.50.1"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[1980,11,1]],"date-time":"1980-11-01T00:00:00Z","timestamp":341884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1980,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Ninety-five patients with pulmonary parenchymal lesions suggestive of malignancy underwent 103 combined puncture-aspiration biopsies using an 18-gauge Rotex biopsy needle. The over-all sensitivity of the procedure was 90 %, and the specificity was 95 %, as determined by pathologic and clinical outcome. Needle biopsy was diagnostic in 69 of 77 patients (90 %) with malignancy. In 3 patients with a false-negative biopsy result, a second needle biopsy was diagnostic, increasing the yield to 94 %. One false-positive biopsy result occurred in a patient with actinomycosis. In the 17 patients in whom no malignancy was found on percutaneous biopsy, subsequent surgical biopsy, culture of aspirate, or stability or disappearance of the lesion within a year or more confirmed the initial diagnosis of nonmalignant disease. Pneumothorax was the only significant complication, requiring tube drainage after 6 biopsies (5.8 %) Our study confirms that needle puncture-aspiration is an extremely reliable technique in diagnosing lung malignancy and is adaptable to use in a community teaching hospital.<\/jats:p>","DOI":"10.1164\/arrd.1980.122.5.725","type":"journal-article","created":{"date-parts":[[2015,10,22]],"date-time":"2015-10-22T10:30:45Z","timestamp":1445509845000},"page":"725-729","source":"Crossref","is-referenced-by-count":59,"title":["Sensitivity and Specificity of Needle Biopsy in Lung Malignancy"],"prefix":"10.1093","volume":"122","author":[{"given":"Robert H.","family":"Poe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard E.","family":"Tobin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1980,11,1]]},"container-title":["American Review of Respiratory Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/122\/5\/725\/67678566\/ajrccm_122_5_725.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/122\/5\/725\/67678566\/ajrccm_122_5_725.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T05:46:22Z","timestamp":1774935982000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/122\/5\/725\/8565299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,11,1]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1980,11,1]]},"published-print":{"date-parts":[[1980,11,1]]}},"URL":"https:\/\/doi.org\/10.1164\/arrd.1980.122.5.725","relation":{},"ISSN":["0003-0805"],"issn-type":[{"value":"0003-0805","type":"print"}],"subject":[],"published-other":{"date-parts":[[1980,11]]},"published":{"date-parts":[[1980,11,1]]}}}