{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:38:52Z","timestamp":1774939132742,"version":"3.50.1"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1983,7,1]],"date-time":"1983-07-01T00:00:00Z","timestamp":425865600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The association of Pneumocystis carinii pneumonia and cytomegalovirus infection in apparently healthy intravenous drug abusers or homosexual males recently has been described. Two patients with this syndrome were seen recently at our institution. Bronchoalveolar lavage samples from these two patients, taken at the time of bronchoscopy, were analyzed. In both patients a significant increase in inflammatory cells (polymorphonuclear cells) and evidence for polyclonal B cell activation, as measured by a reverse hemolytic plaque assay was seen compared to normal persons (p &amp;lt; 0.01 both comparisons). IgM and IgG anti-Pneumocystis carinii antibody titers were elevated in the lavage fluid of one patient each. One patient, originally diagnosed as having \u201cHamman-Rich Syndrome,\u201d demonstrated unequivocal chest X-ray improvement with prednisone therapy alone. These observations suggest that the lungs of these two patients were the site of an intense inflammatory response, which was not reflected in studies with peripheral blood.<\/jats:p>","DOI":"10.1164\/arrd.1983.128.1.189","type":"journal-article","created":{"date-parts":[[2015,10,4]],"date-time":"2015-10-04T22:51:18Z","timestamp":1443999078000},"page":"189-194","source":"Crossref","is-referenced-by-count":35,"title":["Immunologic Alterations in Bronchoalveolar Lavage Fluid in the Acquired Immunodeficiency Syndrome (AIDS)"],"prefix":"10.1093","volume":"128","author":[{"given":"John A.","family":"Rankin","sequence":"first","affiliation":[{"name":"Requests for reprints should be addressed to Dr. John A. Rankin, Pulmonary Disease Section, Yale University School of Medicine, P.O. Box 3333, 333 Cedar St., New Haven, CT 06510"},{"name":"Supported in part by an award from the Charles E. Culpeper Foundation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter D.","family":"Walzer","sequence":"additional","affiliation":[{"name":"Supported in part by Research Service, Veterans Administration, and an American Cancer Society Research Grant"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Dwyer","sequence":"additional","affiliation":[{"name":"Supported in part by Grant No. AI-11785 from the National Institutes of Health"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol E.","family":"Schrader","sequence":"additional","affiliation":[{"name":"West Haven Veterans Administration Medical Center Departments of Pulmonary Disease and Pathology"},{"name":"Yale University School of Medicine Departments of Pulmonary Disease and Immunology \u00a0 New Haven, Connecticut"},{"name":"University of Cincinnati College of Medicine Department of Infectious Disease"},{"name":"Veterans Administration Medical Center \u00a0 Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa E.","family":"Enriquez","sequence":"additional","affiliation":[{"name":"West Haven Veterans Administration Medical Center Departments of Pulmonary Disease and Pathology"},{"name":"Yale University School of Medicine Departments of Pulmonary Disease and Immunology \u00a0 New Haven, Connecticut"},{"name":"University of Cincinnati College of Medicine Department of Infectious Disease"},{"name":"Veterans Administration Medical Center \u00a0 Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William W.","family":"Merrill","sequence":"additional","affiliation":[{"name":"Supported in part by Research Service, Veterans Administration"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1983,7,1]]},"container-title":["American Review of Respiratory Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/128\/1\/189\/67670640\/ajrccm_128_1_189.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/128\/1\/189\/67670640\/ajrccm_128_1_189.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T05:10:12Z","timestamp":1774933812000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/128\/1\/189\/8562851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,7,1]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1983,7,1]]},"published-print":{"date-parts":[[1983,7,1]]}},"URL":"https:\/\/doi.org\/10.1164\/arrd.1983.128.1.189","relation":{},"ISSN":["0003-0805"],"issn-type":[{"value":"0003-0805","type":"print"}],"subject":[],"published-other":{"date-parts":[[1983,7]]},"published":{"date-parts":[[1983,7,1]]}}}