{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T01:19:54Z","timestamp":1775783994121,"version":"3.50.1"},"reference-count":162,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Lung transplantation is the only definitive therapy for many forms of end-stage lung diseases. However, the success of lung transplantation is limited by many factors: (1) Too few lungs available for transplantation due to limited donors or injury to the donor lung; (2) current methods of preservation of excised lungs do not allow extended periods of time between procurement and implantation; (3) acute graft failure is more common with lungs than other solid organs, thus contributing to poorer short-term survival after lung transplant compared with that for recipients of other organs; (4) lung transplant recipients are particularly vulnerable to pulmonary infections; and (5) chronic allograft dysfunction, manifest by bronchiolitis obliterans syndrome, is frequent and limits long-term survival. Scientific advances may provide significant improvements in the outcome of lung transplantation. The National Heart, Lung, and Blood Institute convened a working group of investigators on June 14\u201315, 2004, in Bethesda, Maryland, to identify opportunities for scientific advancement in lung transplantation, including basic and clinical research. This workshop provides a framework to identify critical issues related to clinical lung transplantation, and to delineate important areas for productive scientific investigation.<\/jats:p>","DOI":"10.1164\/rccm.200501-098ws","type":"journal-article","created":{"date-parts":[[2005,7,14]],"date-time":"2005-07-14T20:36:04Z","timestamp":1121373364000},"page":"944-955","source":"Crossref","is-referenced-by-count":77,"title":["Lung Transplantation"],"prefix":"10.1093","volume":"172","author":[{"given":"David S.","family":"Wilkes","sequence":"first","affiliation":[{"name":"Indiana University School of Medicine, Indianapolis, Indiana; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and National Heart, Lung, and Blood Institute, Bethesda, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas M.","family":"Egan","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine, Indianapolis, Indiana; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and National Heart, Lung, and Blood Institute, Bethesda, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert Y.","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine, Indianapolis, Indiana; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and National Heart, Lung, and Blood Institute, Bethesda, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2005,10,15]]},"reference":[{"key":"2026032606121136900_BIB1","first-page":"933","volume-title":"J Heart Lung Transplant","year":"2004"},{"key":"2026032606121136900_BIB2","first-page":"667","volume-title":"N Engl J Med","year":"2003"},{"key":"2026032606121136900_BIB3"},{"key":"2026032606121136900_BIB4","first-page":"290","volume-title":"Am Rev Respir 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