{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T13:42:54Z","timestamp":1789825374798,"version":"4.0.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>The impact of REM-predominant sleep-disordered breathing (SDB) on sleepiness, quality of life (QOL), and sleep maintenance is uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the association of SDB during REM sleep with daytime sleepiness, health-related QOL, and difficulty maintaining sleep, in comparison to their association with SDB during non-REM sleep in a community-based cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cross-sectional analysis of 5,649 Sleep Heart Health Study participants (mean age 62.5 [SD = 10.9], 52.6% women, 22.6% ethnic minorities). SDB during REM and non-REM sleep was quantified using polysomnographically derived apnea-hypopnea index in REM (AHIREM) and non-REM (AHINREM) sleep. Sleepiness, sleep maintenance, and QOL were respectively quantified using the Epworth Sleepiness Scale (ESS), the Sleep Heart Health Study Sleep Habit Questionnaire, and the physical and mental composites scales of the Medical Outcomes Study Short Form (SF)-36.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements and Main Results<\/jats:title>\n                    <jats:p>AHIREM was not associated with the ESS scores or the physical and mental components scales scores of the SF-36 after adjusting for demographics, body mass index, and AHINREM. AHIREM was not associated with frequent difficulty maintaining sleep or early awakening from sleep. AHINREM was associated with the ESS score (\u03b2 = 0.25; 95% confidence interval [CI], 0.16 to 0.34) and the physical (\u03b2 = \u22120.12; 95% CI, \u22120.42 to \u22120.01) and mental (\u03b2 = \u22120.20; 95% CI, \u22120.20 to \u22120.01) components scores of the SF-36 adjusting for demographics, body mass index, and AHIREM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a community-based sample of middle-aged and older adults, REM-predominant SDB is not independently associated with daytime sleepiness, impaired health-related QOL, or self-reported sleep disruption.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1164\/rccm.200908-1304oc","type":"journal-article","created":{"date-parts":[[2010,1,21]],"date-time":"2010-01-21T22:10:52Z","timestamp":1264111852000},"page":"997-1002","source":"Crossref","is-referenced-by-count":83,"title":["Sleepiness, Quality of Life, and Sleep Maintenance in REM versus non-REM Sleep-disordered Breathing"],"prefix":"10.1093","volume":"181","author":[{"given":"Hassan A.","family":"Chami","sequence":"first","affiliation":[{"name":"Boston University School of Medicine, Boston, Massachusetts"},{"name":"Veterans Affairs Boston Health Care System, West Roxbuy, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol M.","family":"Baldwin","sequence":"additional","affiliation":[{"name":"Arizona State University College of Nursing and Health Innovation, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Silverman","sequence":"additional","affiliation":[{"name":"MedStar Research Institute, Hyattsville, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[{"name":"University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Rapoport","sequence":"additional","affiliation":[{"name":"New York University School of Medicine, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naresh M.","family":"Punjabi","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Gottlieb","sequence":"additional","affiliation":[{"name":"Boston University School of Medicine, Boston, Massachusetts"},{"name":"Veterans Affairs Boston Health Care System, West Roxbuy, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,5,1]]},"reference":[{"key":"2026032102173871000_BIB1","first-page":"540","volume-title":"Chest","year":"1987"},{"key":"2026032102173871000_BIB2","first-page":"1202","volume-title":"Chest","year":"1989"},{"key":"2026032102173871000_BIB3","first-page":"30","volume-title":"Chest","year":"1993"},{"key":"2026032102173871000_BIB4","first-page":"502","volume-title":"Am J Respir Crit Care Med","year":"1999"},{"key":"2026032102173871000_BIB5","first-page":"722","volume-title":"Am J Respir Crit Care Med","year":"1994"},{"key":"2026032102173871000_BIB6","first-page":"96","volume-title":"Sleep","year":"2001"},{"key":"2026032102173871000_BIB7","first-page":"3350","volume-title":"Chest","year":"2005"},{"key":"2026032102173871000_BIB8","year":"2005"},{"key":"2026032102173871000_BIB9","first-page":"552","volume-title":"Psychophysiology","year":"1990"},{"key":"2026032102173871000_BIB10","first-page":"609","volume-title":"Sleep","year":"1998"},{"key":"2026032102173871000_BIB11","first-page":"167","volume-title":"Am J Respir Crit Care Med","year":"1996"},{"key":"2026032102173871000_BIB12","first-page":"980","volume-title":"Chest","year":"1998"},{"key":"2026032102173871000_BIB13","first-page":"307","volume-title":"Sleep","year":"2002"},{"key":"2026032102173871000_BIB14","first-page":"1077","volume-title":"Sleep","year":"1997"},{"key":"2026032102173871000_BIB15","first-page":"759","volume-title":"Sleep","year":"1998"},{"key":"2026032102173871000_BIB16","first-page":"749","volume-title":"Sleep","year":"1998"},{"key":"2026032102173871000_BIB17","first-page":"843","volume-title":"Sleep","year":"2002"},{"key":"2026032102173871000_BIB18","first-page":"540","volume-title":"Sleep","year":"1991"},{"key":"2026032102173871000_BIB19","first-page":"376","volume-title":"Sleep","year":"1992"},{"key":"2026032102173871000_BIB20","first-page":"473","volume-title":"Med Care","year":"1992"},{"key":"2026032102173871000_BIB21","first-page":"724","volume-title":"Med Care","year":"1988"},{"key":"2026032102173871000_BIB22","first-page":"907","volume-title":"JAMA","year":"1989"},{"key":"2026032102173871000_BIB23","first-page":"925","volume-title":"JAMA","year":"1989"},{"key":"2026032102173871000_BIB24","first-page":"1465","volume-title":"Am J Respir Crit Care Med","year":"2000"},{"key":"2026032102173871000_BIB25","first-page":"91","volume-title":"Neurophysiol Clin","year":"1993"},{"key":"2026032102173871000_BIB26","first-page":"3","volume-title":"Sleep Med Rev","year":"1998"},{"key":"2026032102173871000_BIB27","first-page":"145","volume-title":"J Psychosom Res","year":"1997"},{"key":"2026032102173871000_BIB28","first-page":"703","volume-title":"Sleep","year":"1994"},{"key":"2026032102173871000_BIB29","first-page":"453","volume-title":"Accid Anal Prev","year":"1997"},{"key":"2026032102173871000_BIB30","first-page":"461","volume-title":"Am J Respir Crit Care Med","year":"1999"}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/181\/9\/997\/67309841\/ajrccm_181_9_997.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/181\/9\/997\/67309841\/ajrccm_181_9_997.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T06:17:41Z","timestamp":1774073861000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/181\/9\/997\/8515533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,1]]},"references-count":30,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2010,5,1]]},"published-print":{"date-parts":[[2010,5,1]]}},"URL":"https:\/\/doi.org\/10.1164\/rccm.200908-1304oc","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2010,5]]},"published":{"date-parts":[[2010,5,1]]}}}