{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:21:39Z","timestamp":1774120899089,"version":"3.50.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12,1]]},"DOI":"10.1164\/rccm.201310-1912ed","type":"journal-article","created":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T13:45:05Z","timestamp":1385905505000},"page":"1281-1282","source":"Crossref","is-referenced-by-count":8,"title":["Human Rhinovirus, Wheezing Illness, and the Primary Prevention of Childhood Asthma"],"prefix":"10.1093","volume":"188","author":[{"suffix":"Jr.","given":"Carlos A.","family":"Camargo","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts, and, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2013,12,1]]},"reference":[{"key":"2026032100413871800_bib1","doi-asserted-by":"crossref","first-page":"7418","DOI":"10.1128\/JVI.02290-09","article-title":"The ABCs of rhinoviruses, wheezing, and asthma","volume":"84","author":"Gern","year":"2010","journal-title":"J Virol"},{"key":"2026032100413871800_bib2","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.prrv.2012.04.002","article-title":"New molecular virus detection methods and their clinical value in lower respiratory tract infections in children","volume":"14","author":"Jartti","year":"2013","journal-title":"Paediatr Respir Rev"},{"key":"2026032100413871800_bib3","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1067\/mai.2003.33","article-title":"Rhinovirus-induced wheezing in infancy\u2014the first sign of childhood asthma?","volume":"111","author":"Kotaniemi-Syrj\u00e4nen","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"2026032100413871800_bib4","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.jaci.2006.12.669","article-title":"Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma","volume":"119","author":"Kusel","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"2026032100413871800_bib5","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1164\/rccm.200802-309OC","article-title":"Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children","volume":"178","author":"Jackson","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032100413871800_bib6","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1164\/rccm.200804-579OC","article-title":"Evidence of a causal role of winter virus infection during infancy in early childhood asthma","volume":"178","author":"Wu","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032100413871800_bib7","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1097\/INF.0b013e31829061e8","article-title":"Association between respiratory syncytial virus hospitalizations in infants and respiratory sequelae: systematic review and meta-analysis","volume":"32","author":"R\u00e9gnier","year":"2013","journal-title":"Pediatr Infect Dis J"},{"key":"2026032100413871800_bib8","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1001\/archpediatrics.2011.1669","article-title":"Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis","volume":"166","author":"Mansbach","year":"2012","journal-title":"Arch Pediatr Adolesc Med"},{"key":"2026032100413871800_bib9","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1056\/NEJMoa1211917","article-title":"Respiratory syncytial virus and recurrent wheeze in healthy preterm infants","volume":"368","author":"Blanken","year":"2013","journal-title":"N Engl J Med"},{"key":"2026032100413871800_bib10","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1164\/rccm.201303-0498OC","article-title":"HRV-C infection in young children with acute wheeze is associated with increased acute respiratory hospital admissions","volume":"188","author":"Cox","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032100413871800_bib11","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1399-3038.2011.01170.x","article-title":"Rhinovirus-induced bronchiolitis and asthma development","volume":"22","author":"Jartti","year":"2011","journal-title":"Pediatr Allergy Immunol"},{"key":"2026032100413871800_bib12","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1183\/09031936.00193310","article-title":"Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheeze","volume":"39","author":"Kusel","year":"2012","journal-title":"Eur Respir J"},{"key":"2026032100413871800_bib13","doi-asserted-by":"crossref","first-page":"e180","DOI":"10.1542\/peds.2010-0442","article-title":"Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma","volume":"127","author":"Camargo","year":"2011","journal-title":"Pediatrics"},{"key":"2026032100413871800_bib14","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1056\/NEJMoa1211592","article-title":"Rhinovirus wheezing illness and genetic risk of childhood-onset asthma","volume":"368","author":"Cal\u0131\u015fkan","year":"2013","journal-title":"N Engl J Med"},{"key":"2026032100413871800_bib15","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1136\/thoraxjnl-2011-201183","article-title":"Significance of the microbiome in obstructive lung disease","volume":"67","author":"Han","year":"2012","journal-title":"Thorax"}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/188\/11\/1281\/67235619\/ajrccm_188_11_1281.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/188\/11\/1281\/67235619\/ajrccm_188_11_1281.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T04:43:26Z","timestamp":1774068206000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/188\/11\/1281\/8506316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,1]]},"references-count":15,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2013,12,1]]},"published-print":{"date-parts":[[2013,12,1]]}},"URL":"https:\/\/doi.org\/10.1164\/rccm.201310-1912ed","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2013,12]]},"published":{"date-parts":[[2013,12,1]]}}}