{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T07:17:30Z","timestamp":1789629450984,"version":"build-2803163510"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100002924","name":"FEDER","doi-asserted-by":"publisher","award":["PI13\/00743"],"award-info":[{"award-number":["PI13\/00743"]}],"id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007509","name":"SEPAR","doi-asserted-by":"publisher","award":["039\/2013"],"award-info":[{"award-number":["039\/2013"]}],"id":[{"id":"10.13039\/501100007509","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>Continuous positive airway pressure (CPAP) is the treatment of choice in patients with symptomatic obstructive sleep apnea (OSA). CPAP treatment improves quality of life (QoL) in men with OSA, but its role in women has not yet been assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the effect of CPAP on QoL in women with moderate to severe OSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a multicenter, open-label randomized controlled trial in 307 consecutive women diagnosed with moderate to severe OSA (apnea\u2013hypopnea index, \u226515) in 19 Spanish sleep units. Women were randomized to receive effective CPAP therapy (n\u2009=\u2009151) or conservative treatment (n\u2009=\u2009156) for 3 months. The primary endpoint was the change in QoL based on the Quebec Sleep Questionnaire. Secondary endpoints included changes in daytime sleepiness, mood state, anxiety, and depression. Data were analyzed on an intention-to-treat basis with adjustment for baseline values and other relevant clinical variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements and Main Results<\/jats:title>\n                    <jats:p>The women in the study had a mean (SD) age of 57.1 (10.1) years and a mean (SD) Epworth Sleepiness Scale score of 9.8 (4.4), and 77.5% were postmenopausal. Compared with the control group, the CPAP group achieved a significantly greater improvement in all QoL domains of the Quebec Sleep Questionnaire (adjusted treatment effect between 0.53 and 1.33; P\u2009&amp;lt;\u20090.001 for all domains), daytime sleepiness (\u22122.92; P\u2009&amp;lt;\u20090.001), mood state (\u22124.24; P \u2009= 0.012), anxiety (\u22120.89; P\u2009=\u20090.014), depression (\u22120.85; P\u2009=\u20090.016), and the physical component summary of the 12-item Short Form Health Survey (2.78; P\u2009=\u20090.003).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In women with moderate or severe OSA, 3 months of CPAP therapy improved QoL, mood state, anxiety and depressive symptoms, and daytime sleepiness compared with conservative treatment.<\/jats:p>\n                    <jats:p>Clinical trial registered with www.clinicaltrials.gov (NCT02047071).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1164\/rccm.201602-0265oc","type":"journal-article","created":{"date-parts":[[2016,5,15]],"date-time":"2016-05-15T16:45:15Z","timestamp":1463330715000},"page":"1286-1294","source":"Crossref","is-referenced-by-count":91,"title":["Continuous Positive Airway Pressure Improves Quality of Life in Women with Obstructive Sleep Apnea. A Randomized Controlled Trial"],"prefix":"10.1093","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2632-3073","authenticated-orcid":false,"given":"Francisco","family":"Campos-Rodriguez","sequence":"first","affiliation":[{"name":"Respiratory Department, Hospital Universitario de Valme, Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Queipo-Corona","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Universitario Marques de Valdecilla, Santander, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Carmona-Bernal","sequence":"additional","affiliation":[{"name":"Medical-Surgical Unit of Respiratory Diseases, Virgen del Rocio University Hospital, Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernabe","family":"Jurado-Gamez","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Reina Sofia University Hospital, Institute of Biomedical Research Maimonides (IMIBIC), University of Cordoba, Cordoba, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Cordero-Guevara","sequence":"additional","affiliation":[{"name":"Gerencia de Atenci\u00f3n Primaria de Burgos, Burgos, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Reyes-Nu\u00f1ez","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Universitario de Valme, Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Troncoso-Acevedo","sequence":"additional","affiliation":[{"name":"Respiratory Department, Fundaci\u00f3n Jimenez Diaz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Araceli","family":"Abad-Fernandez","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Universitario de Getafe, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Teran-Santos","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Universitario de Burgos, Burgos, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Caballero-Rodriguez","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Morales Meseguer, Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Martin-Romero","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Universitario Virgen de la Victoria, Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Encabo-Moti\u00f1o","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Severo Ochoa, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lirios","family":"Sacristan-Bou","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital General de Tomelloso, Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Navarro-Esteva","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Universitario de Gran Canaria Doctor Negr\u00edn, Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Somoza-Gonzalez","sequence":"additional","affiliation":[{"name":"Respiratory Department, Consorcio Sanitario de Terrassa, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan F.","family":"Masa","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain"},{"name":"Respiratory Department, Hospital San Pedro de Alcantara, Caceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A.","family":"Sanchez-Quiroga","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Virgen del Puerto, Caceres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Jara-Chinarro","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Puerta de Hierro, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belen","family":"Orosa-Bertol","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Universitario Doctor Peset, Valencia, Spain; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Martinez-Garcia","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain"},{"name":"Respiratory Department, Hospital Universitario y Politecnico La Fe, Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,11,15]]},"reference":[{"key":"2026032023572543900_bib1","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1093\/aje\/kws342","article-title":"Increased prevalence of sleep-disordered breathing in adults","volume":"177","author":"Peppard","year":"2013","journal-title":"Am J Epidemiol"},{"key":"2026032023572543900_bib2","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1183\/09031936.00212711","article-title":"Sleep apnoea is a common occurrence in females","volume":"41","author":"Franklin","year":"2013","journal-title":"Eur Respir J"},{"key":"2026032023572543900_bib3","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S2213-2600(15)00043-0","article-title":"Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study","volume":"3","author":"Heinzer","year":"2015","journal-title":"Lancet Respir Med"},{"key":"2026032023572543900_bib4","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1164\/ajrccm.149.3.8118642","article-title":"Gender differences in sleep disordered breathing in a community-based sample","volume":"149","author":"Redline","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib5","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The occurrence of sleep-disordered breathing among middle-aged adults","volume":"328","author":"Young","year":"1993","journal-title":"N Engl J Med"},{"key":"2026032023572543900_bib6","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.rmed.2004.03.002","article-title":"Gender differences in obstructive sleep apnea syndrome: a clinical study of 1166 patients","volume":"98","author":"Quintana-Gallego","year":"2004","journal-title":"Respir Med"},{"key":"2026032023572543900_bib7","first-page":"309","article-title":"Differences between men and women in the clinical presentation of patients diagnosed with obstructive sleep apnea syndrome","volume":"28","author":"Shepertycky","year":"2005","journal-title":"Sleep"},{"key":"2026032023572543900_bib8","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1183\/09031936.00043210","article-title":"Sex differences in obstructive sleep apnoea in an elderly French population","volume":"37","author":"Sforza","year":"2011","journal-title":"Eur Respir J"},{"key":"2026032023572543900_bib9","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1164\/ajrccm.163.3.9911064","article-title":"Prevalence of sleep-disordered breathing in women: effects of gender","volume":"163","author":"Bixler","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib10","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1164\/ajrccm.161.5.9904121","article-title":"Gender differences in the polysomnographic features of obstructive sleep apnea","volume":"161","author":"O\u2019Connor","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib11","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1152\/japplphysiol.00264.2002","article-title":"Effect of testosterone on the apneic threshold in women during NREM sleep","volume":"94","author":"Zhou","year":"2003","journal-title":"J Appl Physiol (1985)"},{"key":"2026032023572543900_bib12","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1378\/chest.128.3.1310","article-title":"Determinants affecting health-care utilization in obstructive sleep apnea syndrome patients","volume":"128","author":"Tarasiuk","year":"2005","journal-title":"Chest"},{"key":"2026032023572543900_bib13","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/sleep\/30.9.1173","article-title":"Gender differences in morbidity and health care utilization among adult obstructive sleep apnea patients","volume":"30","author":"Greenberg-Dotan","year":"2007","journal-title":"Sleep"},{"key":"2026032023572543900_bib14","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1152\/japplphysiol.00410.2004","article-title":"Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea","volume":"99","author":"Jordan","year":"2005","journal-title":"J Appl Physiol (1985)"},{"key":"2026032023572543900_bib15","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1152\/jappl.2001.91.5.2248","article-title":"Influence of gender on upper airway mechanics: upper airway resistance and Pcrit","volume":"91","author":"Rowley","year":"2001","journal-title":"J Appl Physiol (1985)"},{"key":"2026032023572543900_bib16","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1152\/japplphysiol.00553.2001","article-title":"Gender differences in upper airway compliance during NREM sleep: role of neck circumference","volume":"92","author":"Rowley","year":"2002","journal-title":"J Appl Physiol (1985)"},{"key":"2026032023572543900_bib17","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1164\/rccm.201311-2012OC","article-title":"Role of sleep apnea and continuous positive airway pressure therapy in the incidence of stroke or coronary heart disease in women","volume":"189","author":"Campos-Rodriguez","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib18","doi-asserted-by":"crossref","first-page":"115","DOI":"10.7326\/0003-4819-156-2-201201170-00006","article-title":"Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment: a cohort study","volume":"156","author":"Campos-Rodriguez","year":"2012","journal-title":"Ann Intern Med"},{"key":"2026032023572543900_bib19","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1164\/ajrccm.159.2.9804061","article-title":"Evidence of the effectiveness of continuous positive airway pressure in the treatment of sleep apnea\/hypopnea syndrome","volume":"159","author":"Ballester","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib20","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/S2213-2600(14)70172-9","article-title":"Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial","volume":"2","author":"McMillan","year":"2014","journal-title":"Lancet Respir Med"},{"key":"2026032023572543900_bib21","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1136\/thoraxjnl-2012-202178","article-title":"Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial","volume":"67","author":"Craig","year":"2012","journal-title":"Thorax"},{"key":"2026032023572543900_bib22","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1164\/rccm.201202-0200OC","article-title":"Continuous positive airway pressure treatment of sleepy patients with milder obstructive sleep apnea: results of the CPAP Apnea Trial North American Program (CATNAP) randomized clinical trial","volume":"186","author":"Weaver","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib23","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/sleep\/34.1.121","article-title":"Effects of continuous positive airway pressure on fatigue and sleepiness in patients with obstructive sleep apnea: data from a randomized controlled trial","volume":"34","author":"Tomfohr","year":"2011","journal-title":"Sleep"},{"key":"2026032023572543900_bib24","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1164\/ajrccm.164.4.2006034","article-title":"Effectiveness of CPAP treatment in daytime function in sleep apnea syndrome: a randomized controlled study with an optimized placebo","volume":"164","author":"Montserrat","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib25","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1016\/S0140-6736(98)10532-9","article-title":"Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial","volume":"353","author":"Jenkinson","year":"1999","journal-title":"Lancet"},{"key":"2026032023572543900_bib26","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/sleep\/34.1.111","article-title":"The effect of CPAP in normalizing daytime sleepiness, quality of life, and neurocognitive function in patients with moderate to severe OSA","volume":"34","author":"Antic","year":"2011","journal-title":"Sleep"},{"key":"2026032023572543900_bib27","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1093\/sleep\/31.11.1551","article-title":"Effects of continuous positive airway pressure on quality of life in patients with moderate to severe obstructive sleep apnea: data from a randomized controlled trial","volume":"31","author":"Siccoli","year":"2008","journal-title":"Sleep"},{"key":"2026032023572543900_bib28","first-page":"A2855","article-title":"Effect of continuous positive airway pressure on quality of life in women with obstructive sleep apnea: a randomized-controlled trial [abstract]","volume":"193","author":"Campos-Rodriguez","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib29","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/thx.2003.011205","article-title":"A new standardised and self-administered quality of life questionnaire specific to obstructive sleep apnoea","volume":"59","author":"Lacasse","year":"2004","journal-title":"Thorax"},{"key":"2026032023572543900_bib30","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"key":"2026032023572543900_bib31","volume-title":"EdITS manual for the profile of mood states.","author":"McNair","year":"1992"},{"key":"2026032023572543900_bib32","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The Hospital Anxiety and Depression Scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"},{"key":"2026032023572543900_bib33","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","article-title":"A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity","volume":"34","author":"Ware","year":"1996","journal-title":"Med Care"},{"key":"2026032023572543900_bib34","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1164\/rccm.200312-1787OC","article-title":"Alternative methods of titrating continuous positive airway pressure: a large multicenter study","volume":"170","author":"Masa","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib35","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1183\/09031936.00064214","article-title":"Obstructive sleep apnoea in the elderly: role of continuous positive airway pressure treatment","volume":"46","author":"Mart\u00ednez-Garc\u00eda","year":"2015","journal-title":"Eur Respir J"},{"key":"2026032023572543900_bib36","doi-asserted-by":"crossref","first-page":"512","DOI":"10.5664\/jcsm.27650","article-title":"Gender differences in obstructive sleep apnea and treatment response to continuous positive airway pressure","volume":"5","author":"Ye","year":"2009","journal-title":"J Clin Sleep Med"},{"key":"2026032023572543900_bib37","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.5664\/jcsm.5020","article-title":"Depressive symptoms before and after treatment of obstructive sleep apnea in men and women","volume":"11","author":"Edwards","year":"2015","journal-title":"J Clin Sleep Med"},{"issue":"4","key":"2026032023572543900_bib38","doi-asserted-by":"crossref","DOI":"10.3310\/hta13040","article-title":"Continuous positive airway pressure devices for the treatment of obstructive sleep apnoea-hypopnoea syndrome: a systematic review and economic analysis","volume":"13","author":"McDaid","year":"2009","journal-title":"Health Technol Assess"},{"key":"2026032023572543900_bib39","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/sleep\/30.6.711","article-title":"Relationship between hours of CPAP use and achieving normal levels of sleepiness and daily functioning","volume":"30","author":"Weaver","year":"2007","journal-title":"Sleep"},{"key":"2026032023572543900_bib40","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/sleep\/27.2.305","article-title":"Associations between gender and measures of daytime somnolence in the Sleep Heart Health Study","volume":"27","author":"Baldwin","year":"2004","journal-title":"Sleep"},{"key":"2026032023572543900_bib41","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1183\/09031936.00177411","article-title":"The impact of ageing and sex on the association between sleepiness and sleep disordered breathing","volume":"40","author":"Morrell","year":"2012","journal-title":"Eur Respir J"},{"key":"2026032023572543900_bib42","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0022-3956(99)00020-5","article-title":"Effect of CPAP treatment on mood states in patients with sleep apnea","volume":"33","author":"Yu","year":"1999","journal-title":"J Psychiatr Res"},{"key":"2026032023572543900_bib43","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(94)91522-9","article-title":"Effect of continuous positive airway pressure treatment on daytime function in sleep apnoea\/hypopnoea syndrome","volume":"343","author":"Engleman","year":"1994","journal-title":"Lancet"},{"key":"2026032023572543900_bib44","doi-asserted-by":"crossref","first-page":"e1001762","DOI":"10.1371\/journal.pmed.1001762","article-title":"Effect of treatment of obstructive sleep apnea on depressive symptoms: systematic review and meta-analysis","volume":"11","author":"Povitz","year":"2014","journal-title":"PLoS Med"},{"key":"2026032023572543900_bib45","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1164\/ajrccm.164.6.2008010","article-title":"Effectiveness of continuous positive airway pressure in mild sleep apnea-hypopnea syndrome","volume":"164","author":"Monasterio","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023572543900_bib46","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.5665\/sleep.2226","article-title":"Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: the Apnea Positive Pressure Long-term Efficacy Study (APPLES)","volume":"35","author":"Kushida","year":"2012","journal-title":"Sleep"},{"key":"2026032023572543900_bib47","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1183\/09031936.06.00062805","article-title":"Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patients","volume":"27","author":"Robinson","year":"2006","journal-title":"Eur Respir J"},{"key":"2026032023572543900_bib48","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1183\/09031936.02.00216902","article-title":"Health-related quality of life in obstructive sleep apnoea","volume":"19","author":"Lacasse","year":"2002","journal-title":"Eur Respir J"}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/194\/10\/1286\/67264840\/ajrccm_194_10_1286.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/194\/10\/1286\/67264840\/ajrccm_194_10_1286.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T03:57:38Z","timestamp":1774065458000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/194\/10\/1286\/8509806"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":48,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2016,11,15]]},"published-print":{"date-parts":[[2016,11,15]]}},"URL":"https:\/\/doi.org\/10.1164\/rccm.201602-0265oc","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2016,11]]},"published":{"date-parts":[[2016,11]]}}}