{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:45:07Z","timestamp":1790491507462,"version":"4.1.0"},"reference-count":55,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>Smoking cessation counseling in conjunction with low-dose computed tomography (LDCT) lung cancer screening is recommended in multiple clinical practice guidelines. The best approach for integrating effective smoking cessation interventions within this setting is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To summarize evidence, identify research gaps, prioritize topics for future research, and propose standardized tools for use in conducting research on smoking cessation interventions within the LDCT lung cancer screening setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The American Thoracic Society convened a multistakeholder committee with expertise in tobacco dependence treatment and\/or LDCT screening. During an in-person meeting, evidence was reviewed, research gaps were identified, and key questions were generated for each of three research domains: (1) target population to study; (2) adaptation, development, and testing of interventions; and (3) implementation of interventions with demonstrated efficacy. We also identified standardized measures for use in conducting this research. A larger stakeholder panel then ranked research questions by perceived importance in an online survey. Final prioritization was generated hierarchically on the basis of average rank assigned.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There was little consensus on which questions within the population domain were of highest priority. Within the intervention domain, research to evaluate the effectiveness in the lung cancer screening setting of evidence-based smoking cessation interventions shown to be effective in other contexts was ranked highest. In the implementation domain, stakeholders prioritized understanding strategies to identify and overcome barriers to integrating smoking cessation in lung cancer screening settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This statement offers an agenda to stimulate research surrounding the integration and implementation of smoking cessation interventions with LDCT lung cancer screening.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1164\/rccm.201709-1858st","type":"journal-article","created":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T10:32:02Z","timestamp":1509532322000},"page":"1202-1212","source":"Crossref","is-referenced-by-count":37,"title":["Stakeholder Research Priorities for Smoking Cessation Interventions within Lung Cancer Screening Programs. An Official American Thoracic Society Research Statement"],"prefix":"10.1093","volume":"196","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9062-409X","authenticated-orcid":false,"given":"Hasmeena","family":"Kathuria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank C.","family":"Detterbeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joelle T.","family":"Fathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Fennig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael K.","family":"Gould","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise G.","family":"Jolicoeur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie R.","family":"Land","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta M.","family":"Massetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Mazzone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard A.","family":"Silvestri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher G.","family":"Slatore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Vachani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven B.","family":"Zeliadt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7712-2135","authenticated-orcid":false,"given":"Renda Soylemez","family":"Wiener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,11,1]]},"reference":[{"key":"2026032023475144900_bib1","volume-title":"Cancer facts and figures 2016","author":"American Cancer Society","year":"2016"},{"key":"2026032023475144900_bib2","volume-title":"United States cancer statistics: 1999\u20132013 incidence and mortality web-based report","author":"U.S. Cancer Statistics Working Group, CDC","year":"2016"},{"issue":"Pt E","key":"2026032023475144900_bib3","first-page":"1","article-title":"Personal habits and indoor combustions. Volume 100E: A review of human carcinogens","volume":"100","author":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans","year":"2012","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"2026032023475144900_bib4","article-title":"The health consequences of smoking\u201450 years of progress: a report of the Surgeon General, 2014 [accessed 2017 May 11]","author":"U.S. Department of Health and Human Services"},{"key":"2026032023475144900_bib5","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.15585\/mmwr.mm6544a2","article-title":"Current Cigarette Smoking Among Adults \u2014 United States, 2005\u20132015","volume":"65","author":"Jamal","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2026032023475144900_bib6","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1056\/NEJMsa1211128","article-title":"21st-Century hazards of smoking and benefits of cessation in the United States","volume":"368","author":"Jha","year":"2013","journal-title":"N Engl J Med"},{"issue":"5","key":"2026032023475144900_bib7","first-page":"CD006103","article-title":"Nicotine receptor partial agonists for smoking cessation","author":"Cahill","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"2026032023475144900_bib8","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1093\/jnci\/djn124","article-title":"The risk of death by age, sex, and smoking status in the United States: putting health risks in context","volume":"100","author":"Woloshin","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"2026032023475144900_bib9","doi-asserted-by":"crossref","first-page":"730","DOI":"10.4065\/84.8.730","article-title":"Treating tobacco dependence in light of the 2008 US Department of Health and Human Services clinical practice guideline","volume":"84","author":"Hays","year":"2009","journal-title":"Mayo Clin Proc"},{"key":"2026032023475144900_bib10","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.15585\/mmwr.mm6552a1","article-title":"Quitting smoking among adults \u2014 United States, 2000\u20132015","volume":"65","author":"Babb","year":"2017","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2026032023475144900_bib11","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJMoa1102873","article-title":"Reduced lung-cancer mortality with low-dose computed tomographic screening","volume":"365","author":"Aberle","year":"2011","journal-title":"N Engl J Med"},{"key":"2026032023475144900_bib12","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/RTI.0000000000000136","article-title":"Computed tomography screening for lung cancer in the National Lung Screening Trial: a cost-effectiveness analysis","volume":"30","author":"Black","year":"2015","journal-title":"J Thorac Imaging"},{"key":"2026032023475144900_bib13","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1164\/rccm.201502-0259OC","article-title":"Racial differences in outcomes within the National Lung Screening Trial: implications for widespread implementation","volume":"192","author":"Tanner","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023475144900_bib14","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1164\/rccm.201508-1671ST","article-title":"An official American Thoracic Society\/American College of Chest Physicians policy statement: implementation of low-dose computed tomography lung cancer screening programs in clinical practice","volume":"192","author":"Wiener","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023475144900_bib15","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1002\/cncr.29926","article-title":"Pairing smoking-cessation services with lung cancer screening: a clinical guideline from the Association for the Treatment of Tobacco Use and Dependence and the Society for Research on Nicotine and Tobacco","volume":"122","author":"Fucito","year":"2016","journal-title":"Cancer"},{"key":"2026032023475144900_bib16","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1200\/JCO.2015.61.2077","article-title":"Cancer screening and diagnosis: opportunities for smoking cessation intervention","volume":"33","author":"Land","year":"2015","journal-title":"J Clin Oncol"},{"key":"2026032023475144900_bib17","volume-title":"Implementation of lung cancer screening: proceedings of a workshop","author":"National Academies of Sciences, Engineering, and Medicine","year":"2017"},{"key":"2026032023475144900_bib18","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.4278\/ajhp.100610-LIT-177","article-title":"A review of tobacco use treatments in U.S. ethnic minority populations","volume":"25","author":"Cox","year":"2011","journal-title":"Am J Health Promot"},{"key":"2026032023475144900_bib19","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1080\/14622200110081435","article-title":"Experience of black participants in the Lung Health Study smoking cessation intervention program","volume":"3","author":"Murray","year":"2001","journal-title":"Nicotine Tob Res"},{"key":"2026032023475144900_bib20","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1093\/her\/cyq010","article-title":"Predictors of retention in smoking cessation treatment among Latino smokers in the Northeast United States","volume":"25","author":"Lee","year":"2010","journal-title":"Health Educ Res"},{"key":"2026032023475144900_bib21","first-page":"325","article-title":"Teachable moments for promoting smoking cessation: the context of cancer care and survivorship","volume":"10","author":"McBride","year":"2003","journal-title":"Cancer Contr"},{"key":"2026032023475144900_bib22","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1093\/her\/18.2.156","article-title":"Understanding the potential of teachable moments: the case of smoking cessation","volume":"18","author":"McBride","year":"2003","journal-title":"Health Educ Res"},{"key":"2026032023475144900_bib23","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1136\/thx.2008.102475","article-title":"Effect of CT screening on smoking habits at 1-year follow-up in the Danish Lung Cancer Screening Trial (DLCST)","volume":"64","author":"Ashraf","year":"2009","journal-title":"Thorax"},{"key":"2026032023475144900_bib24","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1136\/thoraxjnl-2013-203849","article-title":"Smoking habits in the randomised Danish Lung Cancer Screening Trial with low-dose CT: final results after a 5-year screening programme","volume":"69","author":"Ashraf","year":"2014","journal-title":"Thorax"},{"key":"2026032023475144900_bib25","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1001\/jamainternmed.2015.2391","article-title":"Primary care provider-delivered smoking cessation interventions and smoking cessation among participants in the National Lung Screening Trial","volume":"175","author":"Park","year":"2015","journal-title":"JAMA Intern Med"},{"key":"2026032023475144900_bib26","doi-asserted-by":"crossref","first-page":"b1024","DOI":"10.1136\/bmj.b1024","article-title":"Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking: systematic review and meta-analysis","volume":"338","author":"Moore","year":"2009","journal-title":"BMJ"},{"key":"2026032023475144900_bib27","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1513\/AnnalsATS.201312-460OC","article-title":"Smoking behaviors among patients receiving computed tomography for lung cancer screening: systematic review in support of the U.S. Preventive Services Task Force","volume":"11","author":"Slatore","year":"2014","journal-title":"Ann Am Thorac Soc"},{"key":"2026032023475144900_bib28","doi-asserted-by":"crossref","first-page":"157","DOI":"10.21037\/atm.2016.03.54","article-title":"Smoking cessation and lung cancer screening","volume":"4","author":"Pedersen","year":"2016","journal-title":"Ann Transl Med"},{"key":"2026032023475144900_bib29","doi-asserted-by":"crossref","first-page":"3484","DOI":"10.1158\/1055-9965.EPI-09-0895","article-title":"Smoking behavior 1 year after computed tomography screening for lung cancer: effect of physician referral for abnormal CT findings","volume":"18","author":"Styn","year":"2009","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2026032023475144900_bib30","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/hex.12036","article-title":"\u2018The thing is not knowing\u2019: patients\u2019 perspectives on surveillance of an indeterminate pulmonary nodule","volume":"18","author":"Wiener","year":"2015","journal-title":"Health Expect"},{"key":"2026032023475144900_bib31","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1001\/jamainternmed.2015.3558","article-title":"Attitudes and perceptions about smoking cessation in the context of lung cancer screening","volume":"175","author":"Zeliadt","year":"2015","journal-title":"JAMA Intern Med"},{"key":"2026032023475144900_bib32","doi-asserted-by":"crossref","first-page":"485","DOI":"10.7326\/M14-2086","article-title":"Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment","volume":"162","author":"Pinsky","year":"2015","journal-title":"Ann Intern Med"},{"key":"2026032023475144900_bib33","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jacr.2014.08.004","article-title":"Performance of ACR Lung-RADS in a clinical CT lung screening program","volume":"12","author":"McKee","year":"2015","journal-title":"J Am Coll Radiol"},{"key":"2026032023475144900_bib34","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s00432-015-2105-0","article-title":"Effect of smoking cessation counseling within a randomised study on early detection of lung cancer in Germany","volume":"142","author":"Bade","year":"2016","journal-title":"J Cancer Res Clin Oncol"},{"key":"2026032023475144900_bib35","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1093\/ntr\/ntw010","article-title":"Brief tailored smoking cessation counseling in a lung cancer screening population is feasible: a pilot randomized controlled trial","volume":"18","author":"Marshall","year":"2016","journal-title":"Nicotine Tob Res"},{"key":"2026032023475144900_bib36","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s12971-016-0080-0","article-title":"Effectiveness of advice from physician and nurse on smoking cessation stage in Taiwanese male smokers attending a community-based integrated screening program","volume":"14","author":"Luh","year":"2016","journal-title":"Tob Induc Dis"},{"key":"2026032023475144900_bib37","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.lungcan.2011.10.011","article-title":"A pilot test of a combined tobacco dependence treatment and lung cancer screening program","volume":"76","author":"Ferketich","year":"2012","journal-title":"Lung Cancer"},{"key":"2026032023475144900_bib38","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.lungcan.2011.10.006","article-title":"The effectiveness of a computer-tailored smoking cessation intervention for participants in lung cancer screening: a randomised controlled trial","volume":"76","author":"van der Aalst","year":"2012","journal-title":"Lung Cancer"},{"key":"2026032023475144900_bib39","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.lungcan.2003.10.001","article-title":"Effectiveness of smoking cessation self-help materials in a lung cancer screening population","volume":"44","author":"Clark","year":"2004","journal-title":"Lung Cancer"},{"key":"2026032023475144900_bib40","doi-asserted-by":"crossref","first-page":"e78S","DOI":"10.1378\/chest.12-2350","article-title":"Screening for lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"143","author":"Detterbeck","year":"2013","journal-title":"Chest"},{"key":"2026032023475144900_bib41","doi-asserted-by":"crossref","first-page":"330","DOI":"10.7326\/M13-2771","article-title":"Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement","volume":"160","author":"Moyer","year":"2014","journal-title":"Ann Intern Med"},{"key":"2026032023475144900_bib42","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1093\/ntr\/ntv177","article-title":"Readiness of lung cancer screening sites to deliver smoking cessation treatment: current practices, organizational priority, and perceived barriers","volume":"18","author":"Ostroff","year":"2016","journal-title":"Nicotine Tob Res"},{"key":"2026032023475144900_bib43","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/14622200210123581","article-title":"Biochemical verification of tobacco use and cessation","volume":"4","author":"SRNT Subcommittee on Biochemical Verification","year":"2002","journal-title":"Nicotine Tob Res"},{"key":"2026032023475144900_bib44","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1360-0443.2004.00995.x","article-title":"Outcome criteria in smoking cessation trials: proposal for a common standard","volume":"100","author":"West","year":"2005","journal-title":"Addiction"},{"key":"2026032023475144900_bib45","article-title":"Tobacco use and cessation in cancer screening, diagnosis, treatment, and survivorship [accessed 2017 May 14]","author":"National Cancer Institute, Division of Cancer Control and Population Sciences"},{"key":"2026032023475144900_bib46","article-title":"Kessler psychological distress scale [accessed 2017 May 14]","author":"Kessler"},{"key":"2026032023475144900_bib47","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1111\/j.1360-0443.1991.tb01879.x","article-title":"The Fagerstr\u00f6m Test for Nicotine Dependence: a revision of the Fagerstr\u00f6m Tolerance Questionnaire","volume":"86","author":"Heatherton","year":"1991","journal-title":"Br J Addict"},{"key":"2026032023475144900_bib48","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.addbeh.2006.07.016","article-title":"Readiness to change smoking behavior in adolescents with psychiatric disorders","volume":"32","author":"Apodaca","year":"2007","journal-title":"Addict Behav"},{"key":"2026032023475144900_bib49","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1080\/10810730.2012.665420","article-title":"How do perceptions about cessation outcomes moderate the effectiveness of a gain-framed smoking cessation telephone counseling intervention?","volume":"17","author":"Latimer-Cheung","year":"2012","journal-title":"J Health Commun"},{"key":"2026032023475144900_bib50"},{"key":"2026032023475144900_bib51","volume-title":"PhenX Toolkit"},{"key":"2026032023475144900_bib52","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1164\/rccm.201310-1790ST","article-title":"An official American Thoracic Society research statement: comparative effectiveness research in pulmonary, critical care, and sleep medicine","volume":"188","author":"Carson","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"2026032023475144900_bib53","article-title":"Smoking cessation within the context of lung cancer screening (R01) [accessed 2017 June 26]","author":"U.S. Department of Health and Human Services"},{"issue":"192","key":"2026032023475144900_bib54","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-3-540-69248-5_2","article-title":"Nicotine chemistry, metabolism, kinetics and biomarkers","author":"Benowitz","year":"2009","journal-title":"Handb Exp Pharmacol"},{"key":"2026032023475144900_bib55","doi-asserted-by":"crossref","first-page":"L425","DOI":"10.1152\/ajplung.00343.2016","article-title":"Biomarkers of exposure to new and emerging tobacco delivery products","volume":"313","author":"Schick","year":"2017","journal-title":"Am J Physiol Lung Cell Mol Physiol"}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/196\/9\/1202\/67127429\/ajrccm_196_9_1202.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/196\/9\/1202\/67127429\/ajrccm_196_9_1202.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T03:48:47Z","timestamp":1774064927000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/196\/9\/1202\/8499245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,1]]},"references-count":55,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2017,11,1]]},"published-print":{"date-parts":[[2017,11,1]]}},"URL":"https:\/\/doi.org\/10.1164\/rccm.201709-1858st","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,11]]},"published":{"date-parts":[[2017,11,1]]}}}