{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:16:14Z","timestamp":1787242574058,"version":"build-2736575974"},"reference-count":86,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pulmonary embolism (PE) presents a spectrum of hemodynamic consequences, ranging from being asymptomatic to a life-threatening medical emergency. Management of submassive and massive PE often involves clinicians from multiple specialties, which can potentially delay the development of a unified treatment plan. In addition, patients with submassive PE can deteriorate after their presentation and require escalation of care. Underlying comorbidities such as chronic obstructive pulmonary disease, cancer, congestive heart failure, and interstitial lung disease can impact the patient\u2019s hemodynamic ability to tolerate submassive PE. In this review, we address the definitions, risk stratification (clinical, laboratory, and imaging), management approaches, and long-term outcomes of submassive PE. We also discuss the role of the PE response team in management of patients with PE.<\/jats:p>","DOI":"10.1164\/rccm.201711-2302ci","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T16:43:23Z","timestamp":1524156203000},"page":"588-598","source":"Crossref","is-referenced-by-count":72,"title":["Submassive Pulmonary Embolism"],"prefix":"10.1093","volume":"198","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6808-2992","authenticated-orcid":false,"given":"Parth M.","family":"Rali","sequence":"first","affiliation":[{"name":"Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard J.","family":"Criner","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,9,1]]},"reference":[{"key":"2026032023272162000_bib1","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1056\/NEJMra072753","article-title":"Acute pulmonary embolism","volume":"358","author":"Tapson","year":"2008","journal-title":"N Engl J Med"},{"key":"2026032023272162000_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1183\/13993003.00281-2015","article-title":"Predictors of costs from the hospital perspective of primary pulmonary embolism","volume":"47","author":"Motte","year":"2016","journal-title":"Eur Respir J"},{"key":"2026032023272162000_bib3","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/1358863X16670250","article-title":"Persistent right ventricular dysfunction, functional capacity limitation, exercise intolerance, and quality of life impairment following pulmonary embolism: systematic review with 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