{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T12:49:49Z","timestamp":1772628589994,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:00:00Z","timestamp":1772582400000},"content-version":"vor","delay-in-days":2102,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.atsjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"DOI":"10.1164\/rccm.202003-0746ed","type":"journal-article","created":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T16:37:56Z","timestamp":1586450276000},"page":"1326-1327","update-policy":"https:\/\/doi.org\/10.1164\/crossmarkpolicies","source":"Crossref","is-referenced-by-count":4,"title":["Equipoise and Acumen in Pediatric Acute Respiratory Distress Syndrome Research"],"prefix":"10.1093","volume":"201","author":[{"given":"Peter","family":"Oishi","sequence":"first","affiliation":[{"name":"Benioff Children\u2019s Hospital, University of California, San Francisco, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey R.","family":"Fineman","sequence":"additional","affiliation":[{"name":"Benioff Children\u2019s Hospital, University of California, San Francisco, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,6,1]]},"reference":[{"key":"2026030321392223500_bib1","first-page":"819","article-title":"Incidence and mortality of acute respiratory distress syndrome in children: a systematic review and meta-analysis","volume-title":"Crit Care Med","author":"Schouten","year":"2016"},{"key":"2026030321392223500_bib2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1097\/PCC.0000000000000350","article-title":"Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference","volume":"16","author":"Pediatric Acute Lung Injury Consensus Conference Group","year":"2015","journal-title":"Pediatr Crit Care Med"},{"key":"2026030321392223500_bib3","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","article-title":"Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome","volume":"342","author":"Brower","year":"2000","journal-title":"N Engl J Med"},{"key":"2026030321392223500_bib4","first-page":"57","article-title":"Insights in pediatric ventilation: timing of intubation, ventilatory strategies, and weaning","volume":"13","author":"Turner","year":"2007","journal-title":"Curr Opin Crit Care"},{"key":"2026030321392223500_bib5","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1056\/NEJMoa1214103","article-title":"Prone positioning in severe acute respiratory distress syndrome","volume":"368","author":"Gu\u00e9rin","year":"2013","journal-title":"N Engl J Med"},{"key":"2026030321392223500_bib6","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1056\/NEJMoa1005372","article-title":"Neuromuscular blockers in early acute respiratory distress syndrome","volume":"363","author":"Papazian","year":"2010","journal-title":"N Engl J Med"},{"key":"2026030321392223500_bib7","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1056\/NEJMoa1800385","article-title":"Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome","volume":"378","author":"Combes","year":"2018","journal-title":"N Engl J Med"},{"key":"2026030321392223500_bib8","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJMoa1215554","article-title":"High-frequency oscillation in early acute respiratory distress syndrome","volume":"368","author":"Ferguson","year":"2013","journal-title":"N Engl J Med"},{"key":"2026030321392223500_bib9","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/S0140-6736(09)61069-2","article-title":"Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial","volume":"374","author":"Peek","year":"2009","journal-title":"Lancet"},{"key":"2026030321392223500_bib10","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1056\/NEJMoa1215716","article-title":"High-frequency oscillation for acute respiratory distress syndrome","volume":"368","author":"Young","year":"2013","journal-title":"N Engl J Med"},{"key":"2026030321392223500_bib11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1001\/jama.294.2.229","article-title":"Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial","volume":"294","author":"Curley","year":"2005","journal-title":"JAMA"},{"key":"2026030321392223500_bib12","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1164\/rccm.201507-1381OC","article-title":"Early high-frequency oscillatory ventilation in pediatric acute respiratory failure: a propensity score analysis","volume":"193","author":"Bateman","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"2026030321392223500_bib13","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1164\/rccm.201709-1893OC","article-title":"Does extracorporeal membrane oxygenation improve survival in pediatric acute respiratory failure?","volume":"197","author":"Barbaro","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"2026030321392223500_bib14","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s13613-016-0206-9","article-title":"Short-term effects of neuromuscular blockade on global and regional lung mechanics, oxygenation and ventilation in pediatric acute hypoxemic respiratory failure","volume":"6","author":"Wilsterman","year":"2016","journal-title":"Ann Intensive Care"},{"key":"2026030321392223500_bib15","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1164\/rccm.201909-1807OC","article-title":"Early use of adjunctive therapies for pediatric acute respiratory distress syndrome: a PARDIE study","volume":"201","author":"Rowan","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"2026030321392223500_bib16","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1056\/NEJMoa061895","article-title":"Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury","volume":"354","author":"Wheeler","year":"2006","journal-title":"N Engl J Med"}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/201\/11\/1326\/67180484\/ajrccm_201_11_1326.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/201\/11\/1326\/67180484\/ajrccm_201_11_1326.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T02:39:34Z","timestamp":1772591974000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/201\/11\/1326\/8496356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,1]]},"references-count":16,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,6,1]]},"published-print":{"date-parts":[[2020,6,1]]}},"URL":"https:\/\/doi.org\/10.1164\/rccm.202003-0746ed","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,6]]},"published":{"date-parts":[[2020,6,1]]},"assertion":[{"value":"2020-05-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}