{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T01:52:02Z","timestamp":1769133122583,"version":"3.49.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":692,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["Postdoctoral Fellowship \/ 902655 to LM"],"award-info":[{"award-number":["Postdoctoral Fellowship \/ 902655 to LM"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL148403 to RFH"],"award-info":[{"award-number":["HL148403 to RFH"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["Postdoctoral Fellowship \/ 902655 to LM"],"award-info":[{"award-number":["Postdoctoral Fellowship \/ 902655 to LM"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL148403 to RFH"],"award-info":[{"award-number":["HL148403 to RFH"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.atsjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,3,15]]},"DOI":"10.1164\/rccm.202311-2075ed","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T11:27:21Z","timestamp":1702034841000},"page":"623-625","update-policy":"https:\/\/doi.org\/10.1164\/crossmarkpolicies","source":"Crossref","is-referenced-by-count":0,"title":["Macrophage SPLUNC-ing Clears Bacteria in the Lung"],"prefix":"10.1093","volume":"209","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0203-4146","authenticated-orcid":false,"given":"Rebecca F.","family":"Hough","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Columbia University, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4636-4884","authenticated-orcid":false,"given":"Liberty","family":"Mthunzi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Columbia University, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"2026012204281838300_bib1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s41572-019-0069-0","article-title":"Acute respiratory distress syndrome","volume":"5","author":"Matthay","year":"2019","journal-title":"Nat Rev Dis Primers"},{"key":"2026012204281838300_bib2","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jama.2016.0291","article-title":"Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries","volume":"315","author":"Bellani","year":"2016","journal-title":"JAMA"},{"key":"2026012204281838300_bib3","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1164\/rccm.202308-1393OC","article-title":"Specific inhibition of Orai1-mediated calcium signaling resolves inflammation and clears bacteria in an ARDS model","volume":"209","author":"Ahmad","year":"2024","journal-title":"Am J Respir Crit Care Med"},{"key":"2026012204281838300_bib4","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature04702","article-title":"A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function","volume":"441","author":"Feske","year":"2006","journal-title":"Nature"},{"key":"2026012204281838300_bib5","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.bbrc.2015.02.110","article-title":"Store-operated calcium entry: mechanisms and modulation","volume":"460","author":"Hogan","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"2026012204281838300_bib6","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1165\/rcmb.2020-0452OC","article-title":"A SPLUNC1 peptidomimetic inhibits Orai1 and reduces inflammation in a murine allergic asthma model","volume":"66","author":"Wrennall","year":"2022","journal-title":"Am J Respir Cell Mol Biol"},{"key":"2026012204281838300_bib7","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1021\/acs.biochem.6b00271","article-title":"Structural features essential to the antimicrobial functions of human SPLUNC1","volume":"55","author":"Walton","year":"2016","journal-title":"Biochemistry"},{"key":"2026012204281838300_bib8","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1002\/JLB.MR1118-444R","article-title":"Revisiting the role of calcium in phagosome formation and maturation","volume":"106","author":"Westman","year":"2019","journal-title":"J Leukoc Biol"},{"key":"2026012204281838300_bib9","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1165\/rcmb.2021-0531ST","article-title":"Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report","volume":"66","author":"Kulkarni","year":"2022","journal-title":"Am J Respir Cell Mol Biol"}],"container-title":["American Journal of Respiratory and Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/209\/6\/623\/66426730\/ajrccm_209_6_623.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajrccm\/article-pdf\/209\/6\/623\/66426730\/ajrccm_209_6_623.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T09:28:27Z","timestamp":1769074107000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajrccm\/article\/209\/6\/623\/8427032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":9,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,3,15]]},"published-print":{"date-parts":[[2024,3,15]]}},"URL":"https:\/\/doi.org\/10.1164\/rccm.202311-2075ed","relation":{},"ISSN":["1073-449X","1535-4970"],"issn-type":[{"value":"1073-449X","type":"print"},{"value":"1535-4970","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,3]]},"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2024-03-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}