{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:45:12Z","timestamp":1790646312410,"version":"4.1.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2002,8,1]],"date-time":"2002-08-01T00:00:00Z","timestamp":1028160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The OSLER test represents a simple alternative to the maintenance of wakefulness test. Standard analysis of OSLER test results yields a mean sleep latency (MSL). The aim of this study was to use both MSL and errors (nonresponses to stimulations) to characterize daytime sleepiness in apneic patients. OSLER test results at 9:00 a.m., 11:00 a.m. and 1:30 p.m. were compared in 27 obstructive sleep apnea syndrome patients (50.4 \u00b1 10.4 years; apnea\u2013hypopnea index: 43.05 \u00b1 25.08) and 20 control subjects (C). Not only did obstructive sleep apnea syndrome patients demonstrate earlier sleep onset than control subjects (MSL: 1,788 seconds \u00b1 511 versus 2,335 seconds \u00b1 139, p &amp;lt; 0.001), but they also spent a greater percentage of time making errors than control subjects (5.4% \u00b1 4.7 of total test time versus 0.4% \u00b1 0.4, p &amp;lt; 0.001) with specific error profiles (high prevalence of three to six consecutive errors). When error profile analysis was added to standard sleep latency assessment, up to 40% of patients with normal sleep latency were exhibiting abnormal fluctuation in vigilance. A single 9:00 a.m. OSLER session appeared as sensitive as three consecutive sessions in its use as a means of identifying patients with significant daytime sleepiness. On the other hand, the 1:30 p.m. OSLER test session was least specific to distinguish apneic subjects from normal subjects, suggesting that the OSLER test can identify the afternoon peak in physiologic somnolence.<\/jats:p>","DOI":"10.1164\/rccm.2107065","type":"journal-article","created":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T17:37:17Z","timestamp":1033493837000},"page":"474-478","source":"Crossref","is-referenced-by-count":57,"title":["Analysis of Error Profiles Occurring during the OSLER Test: A Sensitive Mean of Detecting Fluctuations in Vigilance in Patients with Obstructive Sleep Apnea Syndrome"],"prefix":"10.1093","volume":"166","author":[{"given":"Stephanie","family":"Mazza","sequence":"first","affiliation":[{"name":"Sleep Laboratory and Neuropsychological Unit, PRETA Laboratory TIMC CNRS 5525, University Hospital, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Pepin","sequence":"additional","affiliation":[{"name":"Sleep Laboratory and Neuropsychological Unit, PRETA Laboratory TIMC CNRS 5525, University Hospital, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrystele","family":"Deschaux","sequence":"additional","affiliation":[{"name":"Sleep Laboratory and Neuropsychological Unit, PRETA Laboratory TIMC CNRS 5525, University Hospital, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Naegele","sequence":"additional","affiliation":[{"name":"Sleep Laboratory and Neuropsychological Unit, PRETA Laboratory TIMC CNRS 5525, University Hospital, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Levy","sequence":"additional","affiliation":[{"name":"Sleep Laboratory and Neuropsychological Unit, PRETA Laboratory TIMC CNRS 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