{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:43:39Z","timestamp":1791607419468,"version":"4.3.4"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Neutrophils are key players in acute lung injury. Once recruited from the circulation, these cells release cytotoxic molecules that lead to tissue disruption, so their blockade has been advocated to prevent lung damage. However, lung injury also occurs during neutropenia and usually involves a very poor outcome. There is emerging evidence that neutrophils not only contribute to that early damage but also orchestrate later repair. Neutrophils promote epithelial proliferation and are a source of proteases, which are required for the processing of the collagen scar and facilitation of cell migration. This article reviews the effects of neutrophils in repair after acute lung injury, focusing on their role as biovectors for proteases and other molecules involved in tissue remodeling.<\/jats:p>","DOI":"10.1165\/rcmb.2018-0101ps","type":"journal-article","created":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T09:59:05Z","timestamp":1525082345000},"page":"289-294","source":"Crossref","is-referenced-by-count":77,"title":["The Emerging Role of Neutrophils in Repair after Acute Lung Injury"],"prefix":"10.1093","volume":"59","author":[{"given":"Jorge","family":"Bl\u00e1zquez-Prieto","sequence":"first","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain"},{"name":"Departamento de Biolog\u00eda Funcional, Instituto Universitario de Oncolog\u00eda del Principado de Asturias, Universidad de Oviedo, Oviedo, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red (CIBER)-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; and"},{"name":"Unidad de Cuidados Intensivos Cardiol\u00f3gicos, \u00c1rea del Coraz\u00f3n, Hospital Universitario Central de Asturias, Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00e9s","family":"L\u00f3pez-Alonso","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red (CIBER)-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; and"},{"name":"Unidad de Cuidados Intensivos Cardiol\u00f3gicos, \u00c1rea del Coraz\u00f3n, Hospital Universitario Central de Asturias, Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Covadonga","family":"Huidobro","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red (CIBER)-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; and"},{"name":"Unidad de Cuidados Intensivos Cardiol\u00f3gicos, \u00c1rea del Coraz\u00f3n, Hospital Universitario Central de Asturias, Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-3253","authenticated-orcid":false,"given":"Guillermo M.","family":"Albaiceta","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain"},{"name":"Departamento de Biolog\u00eda Funcional, Instituto Universitario de Oncolog\u00eda del Principado de Asturias, Universidad de Oviedo, Oviedo, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red (CIBER)-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; and"},{"name":"Unidad de Cuidados Intensivos Cardiol\u00f3gicos, \u00c1rea del Coraz\u00f3n, Hospital Universitario Central de Asturias, Oviedo, 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