{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T19:31:58Z","timestamp":1684870318264},"reference-count":0,"publisher":"American Scientific Publishers","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["j biomed nanotechnol"],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:p>This study aims to evaluate the efficiency of a novel <jats:italic>in vitro<\/jats:italic> technique in clot capturing and dissolving them by applying magnetic force on magnetic nanoparticles (MNP) carrying thrombolytic agents. It is a quick and simple method to protect patients from a life-threatening\n pulmonary embolism in an emergency to provide time for the medical team. To analyze the in vitro efficiency of nano-magnetic capturing and dissolving of clots (NCDC), different levels of process parameter including strength magnetic field (0.1, 0.2 and 0.3 T) and fluid flow rate (2.5, 5 and\n 7 l\/min) are exposed to different blood clots sizes from 5 \u00d7 10 to 20 \u00d7 10 mm<jats:sup>2<\/jats:sup> (length \u00d7 diameter), in an in vitro flow model. The results show that by increasing the parameters to their maximum values, it is possible to immobilize 100% of the clots and dissolve\n around 61.4% of clots weight. In addition, the clot-dissolving is directly proportional to the magnetic field strength. NCDC is an efficient technique in immobilizing and dissolving the clots and its efficiency depends on process parameters especially the magnetic field.<\/jats:p>","DOI":"10.1166\/jbn.2020.29941623","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T04:52:06Z","timestamp":1611031926000},"page":"1623-1632","source":"Crossref","is-referenced-by-count":2,"title":["<i>In Vitro<\/i> Evaluation of Capturing and Dissolving the Clot by Magnetic Nanoparticles Carrying a Thrombolytic Agents Instead of Temporary Inferior Vena Cava (IVC) Filter"],"prefix":"10.1166","volume":"16","author":[{"given":"Abbas","family":"Moghanizadeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fakhrodin","family":"Ashrafizadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaleh","family":"Varshousaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahshid","family":"Kharaziha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17","container-title":["Journal of Biomedical Nanotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/asp\/jbn\/2020\/00000016\/00000011\/art00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,8]],"date-time":"2021-05-08T04:46:57Z","timestamp":1620449217000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.1166\/jbn.2020.29941623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,1]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11,1]]}},"alternative-id":["1550-7033(20201101)16:11L.1623;1-"],"URL":"https:\/\/doi.org\/10.1166\/jbn.2020.29941623","relation":{},"ISSN":["1550-7033"],"issn-type":[{"value":"1550-7033","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11,1]]}}}