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The nanocarriers performanced as drug deliver vehicles enable the design of diverse drug delivery systems, which could serve multiple purposes, including improved bioavailability, controlled or triggered release and targeted delivery, leading\n to enhanced drug efficacy and lowered drug toxicity. This paper provides an overview on the types of delivery vehicles, functions of drug nanocarriers and types of ligand-based targeting systems and highlights the advances made towards better HCC treatments.<\/jats:p>","DOI":"10.1166\/jbn.2022.3297","type":"journal-article","created":{"date-parts":[[2022,6,18]],"date-time":"2022-06-18T04:42:13Z","timestamp":1655527333000},"page":"660-676","source":"Crossref","is-referenced-by-count":33,"title":["Nanocarrier-Based Tumor-Targeting Drug Delivery Systems for Hepatocellular Carcinoma Treatments: Enhanced Therapeutic Efficacy and Reduced Drug Toxicity"],"prefix":"10.1166","volume":"18","author":[{"given":"Tian","family":"Tian","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, People\u2019s Republic of 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