{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T08:09:34Z","timestamp":1758960574954},"reference-count":0,"publisher":"American Scientific Publishers","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["j nanosci nanotechnol"],"published-print":{"date-parts":[[2020,3,1]]},"abstract":"<jats:p>Elevated industrial production and broaden applications of indium oxide materials have increased concerns over the occupational exposure of industry workers. Respirable In<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub> particles have been identified in the workplaces and lung of indium-processing workers.\n The aim of this study was to assess the indium distribution <jats:italic>in vivo<\/jats:italic> and organs injury induced by nano-In<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub> particles. More than 50% of nano-In<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub> particles were accumulated in the lungs after 8-week exposure period and caused serious pulmonary\n alveolar proteinosis (PAP) and pneumonia. The migration of nano-In<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub> particles from lungs to the other organs was very low and dose not steadily increase the indium burden in those organs except kidney and liver. The repeated intratracheal instillations of nano-In<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub>\n particles into the lungs of Wistar rats were dose-dependent increased the concentrations of serum indium.<\/jats:p>","DOI":"10.1166\/jnn.2020.17173","type":"journal-article","created":{"date-parts":[[2019,9,7]],"date-time":"2019-09-07T04:37:30Z","timestamp":1567831050000},"page":"1383-1390","source":"Crossref","is-referenced-by-count":4,"title":["Organs Distribution and Injury After Repeated Intratracheal Instillations of Nano-In<sub>2<\/sub>O<sub>3<\/sub> Particles into the Lungs of Wistar Rats"],"prefix":"10.1166","volume":"20","author":[{"given":"Zhaofang","family":"Chen","sequence":"first","affiliation":[{"name":"College of Safety Science and Engineering, Nanjing Tech University, Nanjing 210009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Zhao","sequence":"additional","affiliation":[{"name":"CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Science, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Safety Science and Engineering, Nanjing Tech University, Nanjing 210009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongyi","family":"Gao","sequence":"additional","affiliation":[{"name":"College of Safety Science and Engineering, Nanjing Tech University, Nanjing 210009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinxia","family":"Li","sequence":"additional","affiliation":[{"name":"CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Science, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linlin","family":"Chen","sequence":"additional","affiliation":[{"name":"CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Science, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juncheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"College of Safety Science and Engineering, Nanjing Tech University, Nanjing 210009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17","container-title":["Journal of Nanoscience and Nanotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/asp\/jnn\/2020\/00000020\/00000003\/art00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T04:42:07Z","timestamp":1594183327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.1166\/jnn.2020.17173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3,1]]}},"alternative-id":["1533-4880(20200301)20:3L.1383;1-"],"URL":"https:\/\/doi.org\/10.1166\/jnn.2020.17173","relation":{},"ISSN":["1533-4880"],"issn-type":[{"value":"1533-4880","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3,1]]}}}