{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T03:27:20Z","timestamp":1784258840424,"version":"3.55.0"},"reference-count":0,"publisher":"American Scientific Publishers","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["j nanosci nanotechnol"],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:p>To observe the effect of nano-artificial bone and bone marrow mesenchymal stem cells (BMSCs) in the treatment of femoral head osteonecrosis. The bilateral femoral head internal bone defect model was established and divided into three groups. Group A was used to make the defect without\n filling any material as the control, group B was only filled with nano-artificial bone, and group C was filled with composite materials of nano-artificial bone and bone marrow mesenchymal stem cells. The femoral head was examined using radiography and high-resolution focused 48-slice computed\n tomography (CT) at 12 weeks after implantation. A significant difference was found between groups B and C in the aspect of repairing the defect in osteogenesis of the femoral head as compared with the control group. Nano-collagen-based bone has strong osteogenic and osteogenic effects and\n is a good graft material for repairing bone defects of the femoral head. The use of bone marrow mesenchymal stem cells can promote the repair of bone defects, which is of great value in the treatment of osteonecrosis of the femoral head.<\/jats:p>","DOI":"10.1166\/jnn.2020.18708","type":"journal-article","created":{"date-parts":[[2020,7,26]],"date-time":"2020-07-26T04:35:53Z","timestamp":1595738153000},"page":"7775-7780","source":"Crossref","is-referenced-by-count":4,"title":["Imaging Observation of Nano-Artificial Bone in the Repair of the Defect in Osteonecrosis of the Femoral Head"],"prefix":"10.1166","volume":"20","author":[{"given":"Ziyan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Radiology, First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiurong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiology, First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang 157011, Heilongjiang, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance, Hongqi Hospital Affiliated to Mudanjian Medical University, Mudanjian 157011, Heilongjiang, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang 157011, Heilongjiang, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Chai","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang 157011, Heilongjiang, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17","container-title":["Journal of Nanoscience and Nanotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/asp\/jnn\/2020\/00000020\/00000012\/art00072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T11:39:35Z","timestamp":1596541175000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.1166\/jnn.2020.18708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12,1]]}},"alternative-id":["1533-4880(20201201)20:12L.7775;1-"],"URL":"https:\/\/doi.org\/10.1166\/jnn.2020.18708","relation":{},"ISSN":["1533-4880"],"issn-type":[{"value":"1533-4880","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12,1]]}}}