{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:53:46Z","timestamp":1791928426544,"version":"4.3.4"},"reference-count":0,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2012,9,21]]},"DOI":"10.1167\/iovs.12-9677","type":"journal-article","created":{"date-parts":[[2012,8,14]],"date-time":"2012-08-14T23:00:30Z","timestamp":1344985230000},"page":"6389","source":"Crossref","is-referenced-by-count":12,"title":["Neuron-Specific Enolase Is Elevated in Asymptomatic Carriers of Leber's Hereditary Optic Neuropathy"],"prefix":"10.1167","volume":"53","author":[{"given":"Kenneth M.","family":"Yee","sequence":"first","affiliation":[{"name":"From the Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California;2VMR Institute, Huntington Beach, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred N.","family":"Ross-Cisneros","sequence":"additional","affiliation":[{"name":"From the Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Goo","family":"Lee","sequence":"additional","affiliation":[{"name":"From the Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlon Bastos","family":"Da Rosa","sequence":"additional","affiliation":[{"name":"Centro Universitario do Espirito Santo, Colatina, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange R.","family":"Salomao","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Berezovsky","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Rubens","family":"Belfort","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipe","family":"Chicani","sequence":"additional","affiliation":[{"name":"From the Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California;4Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milton","family":"Moraes-Filho","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry","family":"Sebag","sequence":"additional","affiliation":[{"name":"From the Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California;2VMR Institute, Huntington Beach, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerio","family":"Carelli","sequence":"additional","affiliation":[{"name":"IRCCS Instituto di Scienze Neurologiche and Department of Neurological Sciences, University of Bologna, Bologna, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo A.","family":"Sadun","sequence":"additional","affiliation":[{"name":"From the Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","container-title":["Investigative Opthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.12-9677","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:29:36Z","timestamp":1791926976000},"score":1,"resource":{"primary":{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.12-9677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,21]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,9,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.12-9677","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9,21]]}}}