{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:58:34Z","timestamp":1791928714218,"version":"4.3.4"},"reference-count":35,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"13","license":[{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2019,10,16]]},"DOI":"10.1167\/iovs.18-25613","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T17:42:48Z","timestamp":1571247768000},"page":"4303","source":"Crossref","is-referenced-by-count":4,"title":["Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures"],"prefix":"10.1167","volume":"60","author":[{"given":"Juan-Carlos","family":"Martinez-Camarillo","sequence":"first","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States"},{"name":"USC Ginsburg Institute for Biomedical Therapeutics of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine K.","family":"Spee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Viterbi School of Engineering of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran","family":"Nimmagadda","sequence":"additional","affiliation":[{"name":"USC Ginsburg Institute for Biomedical Therapeutics of the University of Southern California, Los Angeles, California, United States"},{"name":"Neuroscience Graduate Program, University of Southern California, Los Angeles, California, United States"},{"name":"USC \u2013 Caltech MD\/PhD Program, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria Paulina","family":"Trujillo-Sanchez","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States"},{"name":"USC Ginsburg Institute for Biomedical Therapeutics of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Hinton","sequence":"additional","affiliation":[{"name":"USC Ginsburg Institute for Biomedical Therapeutics of the University of Southern California, Los Angeles, California, United States"},{"name":"Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Giarola","sequence":"additional","affiliation":[{"name":"Galvani Bioelectronics, Stevenage, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Pikov","sequence":"additional","affiliation":[{"name":"Galvani Bioelectronics, Stevenage, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Sridhar","sequence":"additional","affiliation":[{"name":"Galvani Bioelectronics, Stevenage, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Humayun","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States"},{"name":"USC Ginsburg Institute for Biomedical Therapeutics of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C.","family":"Weitz","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States"},{"name":"USC Ginsburg Institute for Biomedical Therapeutics of the University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"i1552-5783-60-13-4303-b01","doi-asserted-by":"crossref","unstructured":"Campochiaro\n\t\t\t\t\t\t\tPA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tOcular neovascularization.\n\t\t\t\t\tJ Mol Med.\n\t\t\t\t\t2013;\n\t\t\t\t\t91:\n\t\t\t\t\t311\u2013321.","DOI":"10.1007\/s00109-013-0993-5"},{"key":"i1552-5783-60-13-4303-b02","doi-asserted-by":"crossref","unstructured":"Tong\n\t\t\t\t\t\t\tJP,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tYao\n\t\t\t\t\t\t\tYF.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tContribution of VEGF and PEDF to choroidal angiogenesis: a need for balanced expressions.\n\t\t\t\t\tClin Biochem.\n\t\t\t\t\t2006;\n\t\t\t\t\t39:\n\t\t\t\t\t267\u2013276.","DOI":"10.1016\/j.clinbiochem.2005.11.013"},{"key":"i1552-5783-60-13-4303-b03","doi-asserted-by":"crossref","unstructured":"Virgili\n\t\t\t\t\t\t\tG,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tParravano\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tEvans\n\t\t\t\t\t\t\tJR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGordon\n\t\t\t\t\t\t\tI,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLucenteforte\n\t\t\t\t\t\t\tE.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tAnti-vascular endothelial growth factor for diabetic macular oedema: a network meta-analysis.\n\t\t\t\t\tCochrane Database Syst Rev.\n\t\t\t\t\t2017;\n\t\t\t\t\t6:\n\t\t\t\t\tCD007419.","DOI":"10.1002\/14651858.CD007419.pub5"},{"key":"i1552-5783-60-13-4303-b04","doi-asserted-by":"crossref","unstructured":"Solomon\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLindsley\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tVedula\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKrzystolik\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHawkins\n\t\t\t\t\t\t\tB.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tAnti-vascular endothelial growth factor for neovascular age-related macular degeneration.\n\t\t\t\t\tCochrane Database Syst Rev.\n\t\t\t\t\t2014;\n\t\t\t\t\t8:\n\t\t\t\t\tCD005139.","DOI":"10.1002\/14651858.CD005139.pub3"},{"key":"i1552-5783-60-13-4303-b05","unstructured":"McDougal\n\t\t\t\t\t\t\tDH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGamlin\n\t\t\t\t\t\t\tPD.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tAutonomic control of the eye.\n\t\t\t\t\tCompr Physiol.\n\t\t\t\t\t2015;\n\t\t\t\t\t5:\n\t\t\t\t\t439\u2013473."},{"key":"i1552-5783-60-13-4303-b06","doi-asserted-by":"crossref","unstructured":"Casini\n\t\t\t\t\t\t\tG,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDal Monte\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tFornaciari\n\t\t\t\t\t\t\tI,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tFilippi\n\t\t\t\t\t\t\tL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBagnoli\n\t\t\t\t\t\t\tP.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe \u00df-adrenergic system as a possible new target for pharmacologic treatment of neovascular retinal diseases.\n\t\t\t\t\tProg Retin Eye Res.\n\t\t\t\t\t2014;\n\t\t\t\t\t42:\n\t\t\t\t\t103\u2013129.","DOI":"10.1016\/j.preteyeres.2014.06.001"},{"key":"i1552-5783-60-13-4303-b07","doi-asserted-by":"crossref","unstructured":"Smith\n\t\t\t\t\t\t\tPG,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tReddy\n\t\t\t\t\t\t\tH.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tReorganization of cranial sympathetic pathways following neonatal ganglionectomy in the rat.\n\t\t\t\t\tJ Comp Neurol.\n\t\t\t\t\t1990;\n\t\t\t\t\t301:\n\t\t\t\t\t490\u2013500.","DOI":"10.1002\/cne.903010311"},{"key":"i1552-5783-60-13-4303-b08","doi-asserted-by":"crossref","unstructured":"Steinle\n\t\t\t\t\t\t\tJJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPierce\n\t\t\t\t\t\t\tJD,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tClancy\n\t\t\t\t\t\t\tRL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSmith\n\t\t\t\t\t\t\tPG.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tIncreased ocular blood vessel numbers and sizes following chronic sympathectomy in rat.\n\t\t\t\t\tExp Eye Res.\n\t\t\t\t\t2002;\n\t\t\t\t\t74:\n\t\t\t\t\t761\u2013768.","DOI":"10.1006\/exer.2002.1182"},{"key":"i1552-5783-60-13-4303-b09","doi-asserted-by":"crossref","unstructured":"Steinle\n\t\t\t\t\t\t\tJJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSmith\n\t\t\t\t\t\t\tPG.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSensory but not parasympathetic nerves are required for ocular vascular remodeling following chronic sympathectomy in rat.\n\t\t\t\t\tAuton Neurosci Basic Clin.\n\t\t\t\t\t2003;\n\t\t\t\t\t109:\n\t\t\t\t\t34\u201341.","DOI":"10.1016\/j.autneu.2003.09.004"},{"key":"i1552-5783-60-13-4303-b10","doi-asserted-by":"crossref","unstructured":"Steinle\n\t\t\t\t\t\t\tJJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLindsay\n\t\t\t\t\t\t\tNL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLashbrook\n\t\t\t\t\t\t\tBL.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tCervical sympathectomy causes photoreceptor-specific cell death in the rat retina.\n\t\t\t\t\tAuton Neurosci Basic Clin.\n\t\t\t\t\t2005;\n\t\t\t\t\t120:\n\t\t\t\t\t46\u201351.","DOI":"10.1016\/j.autneu.2005.03.004"},{"key":"i1552-5783-60-13-4303-b11","doi-asserted-by":"crossref","unstructured":"Steinle\n\t\t\t\t\t\t\tJJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLashbrook\n\t\t\t\t\t\t\tBL.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tCervical sympathectomy regulates expression of key angiogenic factors in the rat choroid.\n\t\t\t\t\tExp Eye Res.\n\t\t\t\t\t2006;\n\t\t\t\t\t83:\n\t\t\t\t\t16\u201323.","DOI":"10.1016\/j.exer.2005.11.006"},{"key":"i1552-5783-60-13-4303-b12","doi-asserted-by":"crossref","unstructured":"Wiley\n\t\t\t\t\t\t\tLA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBerkowitz\n\t\t\t\t\t\t\tBA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSteinle\n\t\t\t\t\t\t\tJJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSuperior cervical ganglionectomy induces changes in growth factor expression in the rat retina.\n\t\t\t\t\tInvest Opthalmology Vis Sci.\n\t\t\t\t\t2006;\n\t\t\t\t\t47:\n\t\t\t\t\t439\u2013443.","DOI":"10.1167\/iovs.05-0656"},{"key":"i1552-5783-60-13-4303-b13","doi-asserted-by":"crossref","unstructured":"Lashbrook\n\t\t\t\t\t\t\tBL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSteinle\n\t\t\t\t\t\t\tJJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tBeta-adrenergic receptor regulation of pigment epithelial-derived factor expression in rat retina.\n\t\t\t\t\tAut Neurosci.\n\t\t\t\t\t2005;\n\t\t\t\t\t121:\n\t\t\t\t\t33\u201339.","DOI":"10.1016\/j.autneu.2005.05.006"},{"key":"i1552-5783-60-13-4303-b14","doi-asserted-by":"crossref","unstructured":"Wiley\n\t\t\t\t\t\t\tLA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRupp\n\t\t\t\t\t\t\tGR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSteinle\n\t\t\t\t\t\t\tJJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSympathetic innervation regulates basement membrane thickening and pericyte number in rat retina.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t2005;\n\t\t\t\t\t46:\n\t\t\t\t\t744\u2013748.","DOI":"10.1167\/iovs.04-1023"},{"key":"i1552-5783-60-13-4303-b15","unstructured":"Jiang\n\t\t\t\t\t\t\tY,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tZhang\n\t\t\t\t\t\t\tQ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLiu\n\t\t\t\t\t\t\tL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tTang\n\t\t\t\t\t\t\tJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKern\n\t\t\t\t\t\t\tTS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSteinle\n\t\t\t\t\t\t\tJJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t\u00df2-adrenergic receptor knockout mice exhibit a diabetic retinopathy phenotype.\n\t\t\t\t\tPLoS One.\n\t\t\t\t\t2013;\n\t\t\t\t\t8:\n\t\t\t\t\t1\u20139."},{"key":"i1552-5783-60-13-4303-b16","unstructured":"Panjala\n\t\t\t\t\t\t\tSR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tJiang\n\t\t\t\t\t\t\tY,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKern\n\t\t\t\t\t\t\tTS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tThomas\n\t\t\t\t\t\t\tSA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSteinle\n\t\t\t\t\t\t\tJJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tIncreased tumor necrosis factor-alpha, cleaved caspase 3 levels and insulin receptor substrate-1 phosphorylation in the beta(1)-adrenergic receptor knockout mouse.\n\t\t\t\t\tMol Vis.\n\t\t\t\t\t2011;\n\t\t\t\t\t17:\n\t\t\t\t\t1822\u20131828."},{"key":"i1552-5783-60-13-4303-b17","doi-asserted-by":"crossref","unstructured":"Dieguez\n\t\t\t\t\t\t\tHH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRomeo\n\t\t\t\t\t\t\tHE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGonz\u00e1lez Fleitas\n\t\t\t\t\t\t\tMF,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tSuperior cervical gangliectomy induces non-exudative age-related macular degeneration in mice.\n\t\t\t\t\tDMM Dis Model Mech.\n\t\t\t\t\t2018;\n\t\t\t\t\t11.","DOI":"10.1242\/dmm.031641"},{"key":"i1552-5783-60-13-4303-b18","doi-asserted-by":"crossref","unstructured":"Birmingham\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGradinaru\n\t\t\t\t\t\t\tV,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tAnikeeva\n\t\t\t\t\t\t\tP,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tBioelectronic medicines: a research roadmap.\n\t\t\t\t\tNat Rev Drug Discov.\n\t\t\t\t\t2014;\n\t\t\t\t\t13:\n\t\t\t\t\t399\u2013400.","DOI":"10.1038\/nrd4351"},{"key":"i1552-5783-60-13-4303-b19","doi-asserted-by":"crossref","unstructured":"Kim\n\t\t\t\t\t\t\tYT,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRomero-Ortega\n\t\t\t\t\t\t\tMI.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tMaterial considerations for peripheral nerve interfacing.\n\t\t\t\t\tMRS Bull.\n\t\t\t\t\t2012;\n\t\t\t\t\t37:\n\t\t\t\t\t573\u2013580.","DOI":"10.1557\/mrs.2012.99"},{"key":"i1552-5783-60-13-4303-b20","doi-asserted-by":"crossref","unstructured":"Watson\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tVijayan\n\t\t\t\t\t\t\tN.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe sympathetic innervation of the eyes and face: a clinicoanatomic review.\n\t\t\t\t\tClin Anat.\n\t\t\t\t\t1995;\n\t\t\t\t\t8:\n\t\t\t\t\t262\u2013272.","DOI":"10.1002\/ca.980080405"},{"key":"i1552-5783-60-13-4303-b21","doi-asserted-by":"crossref","unstructured":"Wang\n\t\t\t\t\t\t\tFB,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCheng\n\t\t\t\t\t\t\tPM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tChi\n\t\t\t\t\t\t\tHC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKao\n\t\t\t\t\t\t\tCK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLiao\n\t\t\t\t\t\t\tYH.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tAxons of passage and inputs to superior cervical ganglion in rat.\n\t\t\t\t\tAnat Rec.\n\t\t\t\t\t2018;\n\t\t\t\t\t301:\n\t\t\t\t\t1906\u20131916.","DOI":"10.1002\/ar.23953"},{"key":"i1552-5783-60-13-4303-b22","doi-asserted-by":"crossref","unstructured":"Ludwig\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRoss\n\t\t\t\t\t\t\tE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLanghals\n\t\t\t\t\t\t\tN,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWeber\n\t\t\t\t\t\t\tD,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLujan\n\t\t\t\t\t\t\tJL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGeorgakopoulos\n\t\t\t\t\t\t\tD.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe autonomic nervous system.\n\t\t\t\t\tIn:\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDhillon\n\t\t\t\t\t\t\tGS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHorch\n\t\t\t\t\t\t\tKW\n\t\t\t\t\t\t\n\t\t\t\t\t.\n\t\t\t\t\teds.\n\t\t\t\t\tNeuroprosthetics: Theory and Practice.\n\t\t\t\t\tSingapore:\n\t\t\t\t\tWorld Scientific Publishing Company;\n\t\t\t\t\t2017:\n\t\t\t\t\t12\u201339.","DOI":"10.1142\/9789813207158_0002"},{"key":"i1552-5783-60-13-4303-b23","doi-asserted-by":"crossref","unstructured":"Savastano\n\t\t\t\t\t\t\tLE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCastro\n\t\t\t\t\t\t\tAE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tFitt\n\t\t\t\t\t\t\tMR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRath\n\t\t\t\t\t\t\tMF,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRomeo\n\t\t\t\t\t\t\tHE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMu\u00f1oz\n\t\t\t\t\t\t\tEM.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tA standardized surgical technique for rat superior cervical ganglionectomy.\n\t\t\t\t\tJ Neurosci Methods.\n\t\t\t\t\t2010;\n\t\t\t\t\t192:\n\t\t\t\t\t22\u201333.","DOI":"10.1016\/j.jneumeth.2010.07.007"},{"key":"i1552-5783-60-13-4303-b24","unstructured":"Belmonte\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPerez\n\t\t\t\t\t\t\tE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLopez-Briones\n\t\t\t\t\t\t\tLG,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGallar\n\t\t\t\t\t\t\tJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tChronic stimulation of ocular sympathetic fibers in unanesthetized rabbits.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t1987;\n\t\t\t\t\t28:\n\t\t\t\t\t194\u2013197."},{"key":"i1552-5783-60-13-4303-b25","doi-asserted-by":"crossref","unstructured":"Kase\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHe\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSonoda\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\taB-crystallin regulation of angiogenesis by modulation of VEGF.\n\t\t\t\t\tBlood.\n\t\t\t\t\t2010;\n\t\t\t\t\t115:\n\t\t\t\t\t3398\u20133406.","DOI":"10.1182\/blood-2009-01-197095"},{"key":"i1552-5783-60-13-4303-b26","doi-asserted-by":"crossref","unstructured":"Frank\n\t\t\t\t\t\t\tRN.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tGrowth factors in age-related macular degeneration: pathogenic and therapeutic implications.\n\t\t\t\t\tOphthalmic Res.\n\t\t\t\t\t1997;\n\t\t\t\t\t29:\n\t\t\t\t\t341\u2013353.","DOI":"10.1159\/000268032"},{"key":"i1552-5783-60-13-4303-b27","doi-asserted-by":"crossref","unstructured":"Stef\u00e1nsson\n\t\t\t\t\t\t\tE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tOlafsdottir\n\t\t\t\t\t\t\tOB,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tEinarsdottir\n\t\t\t\t\t\t\tAB,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tRetinal oximetry discovers novel biomarkers in retinal and brain diseases.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t2017;\n\t\t\t\t\t58:\n\t\t\t\t\tBIO227\u2013BIO233.","DOI":"10.1167\/iovs.17-21776"},{"key":"i1552-5783-60-13-4303-b28","unstructured":"Wang\n\t\t\t\t\t\t\tH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHan\n\t\t\t\t\t\t\tX,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWittchen\n\t\t\t\t\t\t\tES,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHartnett\n\t\t\t\t\t\t\tME.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tTNF-alpha mediates choroidal neovascularization by upregulating VEGF expression in RPE through ROS-dependent beta-catenin activation.\n\t\t\t\t\tMol Vis.\n\t\t\t\t\t2016;\n\t\t\t\t\t22:\n\t\t\t\t\t116\u2013128."},{"key":"i1552-5783-60-13-4303-b29","doi-asserted-by":"crossref","unstructured":"Boss\n\t\t\t\t\t\t\tJD,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSingh\n\t\t\t\t\t\t\tPK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPandya\n\t\t\t\t\t\t\tHK,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tAssessment of neurotrophins and inflammatory mediators in vitreous of patients with diabetic retinopathy.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t2017;\n\t\t\t\t\t58:\n\t\t\t\t\t5594\u20135603.","DOI":"10.1167\/iovs.17-21973"},{"key":"i1552-5783-60-13-4303-b30","doi-asserted-by":"crossref","unstructured":"Steinle\n\t\t\t\t\t\t\tJJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKrizan-Agbas\n\t\t\t\t\t\t\tD,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSmith\n\t\t\t\t\t\t\tPG.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tRegional regulation of choroidal bloodflow by autonomic innervation in the rat.\n\t\t\t\t\tAm J Physiol.\n\t\t\t\t\t2000;\n\t\t\t\t\t279:\n\t\t\t\t\tR202\u2013R209.","DOI":"10.1152\/ajpregu.2000.279.1.R202"},{"key":"i1552-5783-60-13-4303-b31","doi-asserted-by":"crossref","unstructured":"Kawarai\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKoss\n\t\t\t\t\t\t\tMC.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSympathetic vasoconstriction in the rat anterior choroid is mediated by a1- adrenoceptors.\n\t\t\t\t\tEur J Pharmacol.\n\t\t\t\t\t1999;\n\t\t\t\t\t386:\n\t\t\t\t\t227\u2013233.","DOI":"10.1016\/S0014-2999(99)00784-0"},{"key":"i1552-5783-60-13-4303-b32","unstructured":"Pither\n\t\t\t\t\t\t\tCE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRaj\n\t\t\t\t\t\t\tPP,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tFord\n\t\t\t\t\t\t\tDJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe use of peripheral nerve stimulators for regional anesthesia a review of experimental characteristics, technique, and clinical applications.\n\t\t\t\t\tReg Anesth Pain Med.\n\t\t\t\t\t1985;\n\t\t\t\t\t10:\n\t\t\t\t\t49\u201358."},{"key":"i1552-5783-60-13-4303-b33","doi-asserted-by":"crossref","unstructured":"Mishra\n\t\t\t\t\t\t\tS.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tElectroceuticals in medicine - the brave new future.\n\t\t\t\t\tIndian Heart J.\n\t\t\t\t\t2017;\n\t\t\t\t\t69:\n\t\t\t\t\t685\u2013686.","DOI":"10.1016\/j.ihj.2017.10.001"},{"key":"i1552-5783-60-13-4303-b34","doi-asserted-by":"crossref","unstructured":"Troger\n\t\t\t\t\t\t\tJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKieselbach\n\t\t\t\t\t\t\tG,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tTeuchner\n\t\t\t\t\t\t\tB,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tPeptidergic nerves in the eye, their source and potential pathophysiological relevance.\n\t\t\t\t\tBrain Res Rev.\n\t\t\t\t\t2007;\n\t\t\t\t\t53:\n\t\t\t\t\t39\u201362.","DOI":"10.1016\/j.brainresrev.2006.06.002"},{"key":"i1552-5783-60-13-4303-b35","doi-asserted-by":"crossref","unstructured":"Neuhuber\n\t\t\t\t\t\t\tW,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSchr\u00f6dl\n\t\t\t\t\t\t\tF.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tAutonomic control of the eye and the iris.\n\t\t\t\t\tAuton Neurosci Basic Clin.\n\t\t\t\t\t2011;\n\t\t\t\t\t165:\n\t\t\t\t\t67\u201379.","DOI":"10.1016\/j.autneu.2010.10.004"}],"container-title":["Investigative Opthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2753274","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:10Z","timestamp":1791927070000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2753274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,16]]},"references-count":35,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2019,10,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.18-25613","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10,16]]}}}