{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:58:28Z","timestamp":1791928708666,"version":"4.3.4"},"reference-count":57,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"5","license":[{"start":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T00:00:00Z","timestamp":1555977600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2019,4,23]]},"DOI":"10.1167\/iovs.18-26049","type":"journal-article","created":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T15:31:45Z","timestamp":1556033505000},"page":"1706","source":"Crossref","is-referenced-by-count":9,"title":["Progesterone Application to the Rat Forehead Produces Corneal Antinociception"],"prefix":"10.1167","volume":"60","author":[{"given":"Ian D.","family":"Meng","sequence":"first","affiliation":[{"name":"Center for Excellence in the Neurosciences, University of New England, Biddeford, Maine, United States"},{"name":"Department of Biomedical Sciences, College of Osteopathic Medicine, University of New England, Biddeford, Maine, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen T.","family":"Barton","sequence":"additional","affiliation":[{"name":"Center for Excellence in the Neurosciences, University of New England, Biddeford, Maine, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Goodney","sequence":"additional","affiliation":[{"name":"Center for Excellence in the Neurosciences, University of New England, Biddeford, Maine, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Russell","sequence":"additional","affiliation":[{"name":"Center for Excellence in the Neurosciences, University of New England, Biddeford, Maine, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal E.","family":"Mecum","sequence":"additional","affiliation":[{"name":"Center for Excellence in the Neurosciences, University of New England, Biddeford, Maine, United States"},{"name":"Molecular and Biomedical Sciences, University of Maine, Orono, Maine, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"i1552-5783-60-5-1706-b01","doi-asserted-by":"crossref","unstructured":"Stapleton\n\t\t\t\t\t\t\tF,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tAlves\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBunya\n\t\t\t\t\t\t\tVY,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tTFOS DEWS II Epidemiology Report.\n\t\t\t\t\tOcul Surf.\n\t\t\t\t\t2017;\n\t\t\t\t\t15:\n\t\t\t\t\t334\u2013365.","DOI":"10.1016\/j.jtos.2017.05.003"},{"key":"i1552-5783-60-5-1706-b02","doi-asserted-by":"crossref","unstructured":"McDonald\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPatel\n\t\t\t\t\t\t\tDA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKeith\n\t\t\t\t\t\t\tMS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSnedecor\n\t\t\t\t\t\t\tSJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tEconomic and humanistic burden of dry eye disease in Europe, North America, and Asia: a systematic literature review.\n\t\t\t\t\tOcul Surf.\n\t\t\t\t\t2016;\n\t\t\t\t\t14:\n\t\t\t\t\t144\u2013167.","DOI":"10.1016\/j.jtos.2015.11.002"},{"key":"i1552-5783-60-5-1706-b03","doi-asserted-by":"crossref","unstructured":"Belmonte\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tNichols\n\t\t\t\t\t\t\tJJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCox\n\t\t\t\t\t\t\tSM,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tTFOS DEWS II pain and sensation report.\n\t\t\t\t\tOcul Surf.\n\t\t\t\t\t2017;\n\t\t\t\t\t15:\n\t\t\t\t\t404\u2013437.","DOI":"10.1016\/j.jtos.2017.05.002"},{"key":"i1552-5783-60-5-1706-b04","doi-asserted-by":"crossref","unstructured":"Galor\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLevitt\n\t\t\t\t\t\t\tRC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMcManus\n\t\t\t\t\t\t\tKT,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tAssessment of somatosensory function in patients with idiopathic dry eye symptoms.\n\t\t\t\t\tJAMA Ophthalmol.\n\t\t\t\t\t2016;\n\t\t\t\t\t134:\n\t\t\t\t\t1290\u20131298.","DOI":"10.1001\/jamaophthalmol.2016.3642"},{"key":"i1552-5783-60-5-1706-b05","doi-asserted-by":"crossref","unstructured":"Schaumberg\n\t\t\t\t\t\t\tDA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBuring\n\t\t\t\t\t\t\tJE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSullivan\n\t\t\t\t\t\t\tDA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDana\n\t\t\t\t\t\t\tMR.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tHormone replacement therapy and dry eye syndrome.\n\t\t\t\t\tJAMA.\n\t\t\t\t\t2001;\n\t\t\t\t\t286:\n\t\t\t\t\t2114\u20132119.","DOI":"10.1001\/jama.286.17.2114"},{"key":"i1552-5783-60-5-1706-b06","doi-asserted-by":"crossref","unstructured":"Ren\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWei\n\t\t\t\t\t\t\tF,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDubner\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMurphy\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHoffman\n\t\t\t\t\t\t\tGE.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tProgesterone attenuates persistent inflammatory hyperalgesia in female rats: involvement of spinal NMDA receptor mechanisms.\n\t\t\t\t\tBrain Res.\n\t\t\t\t\t2000;\n\t\t\t\t\t865:\n\t\t\t\t\t272\u2013277.","DOI":"10.1016\/S0006-8993(00)02267-8"},{"key":"i1552-5783-60-5-1706-b07","doi-asserted-by":"crossref","unstructured":"Roglio\n\t\t\t\t\t\t\tI,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBianchi\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGotti\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tNeuroprotective effects of dihydroprogesterone and progesterone in an experimental model of nerve crush injury.\n\t\t\t\t\tNeuroscience.\n\t\t\t\t\t2008;\n\t\t\t\t\t155:\n\t\t\t\t\t673\u2013685.","DOI":"10.1016\/j.neuroscience.2008.06.034"},{"key":"i1552-5783-60-5-1706-b08","doi-asserted-by":"crossref","unstructured":"Liu\n\t\t\t\t\t\t\tX,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLi\n\t\t\t\t\t\t\tW,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDai\n\t\t\t\t\t\t\tL,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tEarly repeated administration of progesterone improves the recovery of neuropathic pain and modulates spinal 18kDa-translocator protein (TSPO) expression.\n\t\t\t\t\tJ Ster Biochem Mol Biol.\n\t\t\t\t\t2014;\n\t\t\t\t\t143:\n\t\t\t\t\t130\u2013140.","DOI":"10.1016\/j.jsbmb.2014.02.017"},{"key":"i1552-5783-60-5-1706-b09","doi-asserted-by":"crossref","unstructured":"Fischer\n\t\t\t\t\t\t\tL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tTorres-Chavez\n\t\t\t\t\t\t\tKE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tClemente-Napimoga\n\t\t\t\t\t\t\tJT,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tThe influence of sex and ovarian hormones on temporomandibular joint nociception in rats.\n\t\t\t\t\tJ Pain.\n\t\t\t\t\t2008;\n\t\t\t\t\t9:\n\t\t\t\t\t630\u2013638.","DOI":"10.1016\/j.jpain.2008.02.006"},{"key":"i1552-5783-60-5-1706-b10","doi-asserted-by":"crossref","unstructured":"Charlet\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLasbennes\n\t\t\t\t\t\t\tF,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDarbon\n\t\t\t\t\t\t\tP,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPoisbeau\n\t\t\t\t\t\t\tP.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tFast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms.\n\t\t\t\t\tPain.\n\t\t\t\t\t2008;\n\t\t\t\t\t139:\n\t\t\t\t\t603\u2013609.","DOI":"10.1016\/j.pain.2008.06.016"},{"key":"i1552-5783-60-5-1706-b11","doi-asserted-by":"crossref","unstructured":"Ortiz-Renteria\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tJuarez-Contreras\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGonzalez-Ramirez\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tTRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain.\n\t\t\t\t\tProc Natl Acad Sci U S A.\n\t\t\t\t\t2018;\n\t\t\t\t\t115:\n\t\t\t\t\tE1657\u2013E1666.","DOI":"10.1073\/pnas.1715972115"},{"key":"i1552-5783-60-5-1706-b12","doi-asserted-by":"crossref","unstructured":"Belmonte\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tAcosta\n\t\t\t\t\t\t\tMC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGallar\n\t\t\t\t\t\t\tJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tNeural basis of sensation in intact and injured corneas.\n\t\t\t\t\tExp Eye Res.\n\t\t\t\t\t2004;\n\t\t\t\t\t78:\n\t\t\t\t\t513\u2013525.","DOI":"10.1016\/j.exer.2003.09.023"},{"key":"i1552-5783-60-5-1706-b13","doi-asserted-by":"crossref","unstructured":"Belmonte\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tAracil\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tAcosta\n\t\t\t\t\t\t\tMC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLuna\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGallar\n\t\t\t\t\t\t\tJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tNerves and sensations from the eye surface.\n\t\t\t\t\tOcul Surf.\n\t\t\t\t\t2004;\n\t\t\t\t\t2:\n\t\t\t\t\t248\u2013253.","DOI":"10.1016\/S1542-0124(12)70112-X"},{"key":"i1552-5783-60-5-1706-b14","doi-asserted-by":"crossref","unstructured":"Acosta\n\t\t\t\t\t\t\tMC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBelmonte\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGallar\n\t\t\t\t\t\t\tJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSensory experiences in humans and single-unit activity in cats evoked by polymodal stimulation of the cornea.\n\t\t\t\t\tJ Physiol.\n\t\t\t\t\t2001;\n\t\t\t\t\t534:\n\t\t\t\t\t511\u2013525.","DOI":"10.1111\/j.1469-7793.2001.t01-1-00511.x"},{"key":"i1552-5783-60-5-1706-b15","doi-asserted-by":"crossref","unstructured":"Marfurt\n\t\t\t\t\t\t\tCF,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDel Toro\n\t\t\t\t\t\t\tDR.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tCorneal sensory pathway in the rat: a horseradish peroxidase tracing study.\n\t\t\t\t\tJ Comp Neurol.\n\t\t\t\t\t1987;\n\t\t\t\t\t261:\n\t\t\t\t\t450\u2013459.","DOI":"10.1002\/cne.902610309"},{"key":"i1552-5783-60-5-1706-b16","doi-asserted-by":"crossref","unstructured":"Meng\n\t\t\t\t\t\t\tID,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBereiter\n\t\t\t\t\t\t\tDA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tDifferential distribution of Fos-like immunoreactivity in the spinal trigeminal nucleus after noxious and innocuous thermal and chemical stimulation of rat cornea.\n\t\t\t\t\tNeuroscience.\n\t\t\t\t\t1996;\n\t\t\t\t\t72:\n\t\t\t\t\t243\u2013254.","DOI":"10.1016\/0306-4522(95)00541-2"},{"key":"i1552-5783-60-5-1706-b17","doi-asserted-by":"crossref","unstructured":"Meng\n\t\t\t\t\t\t\tID,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHu\n\t\t\t\t\t\t\tJW,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBenetti\n\t\t\t\t\t\t\tAP,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBereiter\n\t\t\t\t\t\t\tDA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tEncoding of corneal input in two distinct regions of the spinal trigeminal nucleus in the rat: cutaneous receptive field properties, responses to thermal and chemical stimulation, modulation by diffuse noxious inhibitory controls, and projections to the parabrachial area.\n\t\t\t\t\tJ Neurophysiol.\n\t\t\t\t\t1997;\n\t\t\t\t\t77:\n\t\t\t\t\t43\u201356.","DOI":"10.1152\/jn.1997.77.1.43"},{"key":"i1552-5783-60-5-1706-b18","doi-asserted-by":"crossref","unstructured":"Strassman\n\t\t\t\t\t\t\tAM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tVos\n\t\t\t\t\t\t\tBP.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSomatotopic and laminar organization of fos-like immunoreactivity in the medullary and upper cervical dorsal horn induced by noxious facial stimulation in the rat.\n\t\t\t\t\tJ Comp Neurol.\n\t\t\t\t\t1993;\n\t\t\t\t\t331:\n\t\t\t\t\t495\u2013516.","DOI":"10.1002\/cne.903310406"},{"key":"i1552-5783-60-5-1706-b19","doi-asserted-by":"crossref","unstructured":"Bereiter\n\t\t\t\t\t\t\tDA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHirata\n\t\t\t\t\t\t\tH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHu\n\t\t\t\t\t\t\tJW.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tTrigeminal subnucleus caudalis: beyond homologies with the spinal dorsal horn.\n\t\t\t\t\tPain.\n\t\t\t\t\t2000;\n\t\t\t\t\t88:\n\t\t\t\t\t221\u2013224.","DOI":"10.1016\/S0304-3959(00)00434-6"},{"key":"i1552-5783-60-5-1706-b20","doi-asserted-by":"crossref","unstructured":"Henriquez\n\t\t\t\t\t\t\tVM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tEvinger\n\t\t\t\t\t\t\tC.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe three-neuron corneal reflex circuit and modulation of second-order corneal responsive neurons.\n\t\t\t\t\tExp Brain Res.\n\t\t\t\t\t2007;\n\t\t\t\t\t179:\n\t\t\t\t\t691\u2013702.","DOI":"10.1007\/s00221-006-0826-7"},{"key":"i1552-5783-60-5-1706-b21","doi-asserted-by":"crossref","unstructured":"Hirata\n\t\t\t\t\t\t\tH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tOkamoto\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tTashiro\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBereiter\n\t\t\t\t\t\t\tDA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tA novel class of neurons at the trigeminal subnucleus interpolaris\/caudalis transition region monitors ocular surface fluid status and modulates tear production.\n\t\t\t\t\tJ Neurosci.\n\t\t\t\t\t2004;\n\t\t\t\t\t24:\n\t\t\t\t\t4224\u20134232.","DOI":"10.1523\/JNEUROSCI.0381-04.2004"},{"key":"i1552-5783-60-5-1706-b22","doi-asserted-by":"crossref","unstructured":"Kurose\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMeng\n\t\t\t\t\t\t\tID.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tCorneal dry-responsive neurons in the spinal trigeminal nucleus respond to innocuous cooling in the rat.\n\t\t\t\t\tJ Neurophysiol.\n\t\t\t\t\t2013;\n\t\t\t\t\t109:\n\t\t\t\t\t2517\u20132522.","DOI":"10.1152\/jn.00889.2012"},{"key":"i1552-5783-60-5-1706-b23","doi-asserted-by":"crossref","unstructured":"Meng\n\t\t\t\t\t\t\tID,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKurose\n\t\t\t\t\t\t\tM.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe role of corneal afferent neurons in regulating tears under normal and dry eye conditions.\n\t\t\t\t\tExp Eye Res.\n\t\t\t\t\t2013;\n\t\t\t\t\t117:\n\t\t\t\t\t79\u201387.","DOI":"10.1016\/j.exer.2013.08.011"},{"key":"i1552-5783-60-5-1706-b24","doi-asserted-by":"crossref","unstructured":"Hirata\n\t\t\t\t\t\t\tH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHu\n\t\t\t\t\t\t\tJW,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBereiter\n\t\t\t\t\t\t\tDA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tResponses of medullary dorsal horn neurons to corneal stimulation by CO(2) pulses in the rat.\n\t\t\t\t\tJ Neurophysiol.\n\t\t\t\t\t1999;\n\t\t\t\t\t82:\n\t\t\t\t\t2092\u20132107.","DOI":"10.1152\/jn.1999.82.5.2092"},{"key":"i1552-5783-60-5-1706-b25","doi-asserted-by":"crossref","unstructured":"Meng\n\t\t\t\t\t\t\tID,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBarton\n\t\t\t\t\t\t\tST,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMecum\n\t\t\t\t\t\t\tNE,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKurose\n\t\t\t\t\t\t\tM.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tCorneal sensitivity following lacrimal gland excision in the rat.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t2015;\n\t\t\t\t\t56:\n\t\t\t\t\t3347\u20133354.","DOI":"10.1167\/iovs.15-16717"},{"key":"i1552-5783-60-5-1706-b26","doi-asserted-by":"crossref","unstructured":"Wakuta\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMorishige\n\t\t\t\t\t\t\tN,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tChikama\n\t\t\t\t\t\t\tT,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSeki\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tNagano\n\t\t\t\t\t\t\tT,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tNishida\n\t\t\t\t\t\t\tT.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tDelayed wound closure and phenotypic changes in corneal epithelium of the spontaneously diabetic Goto-Kakizaki rat.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t2007;\n\t\t\t\t\t48:\n\t\t\t\t\t590\u2013596.","DOI":"10.1167\/iovs.05-1168"},{"key":"i1552-5783-60-5-1706-b27","doi-asserted-by":"crossref","unstructured":"Shimada\n\t\t\t\t\t\t\tSG,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLaMotte\n\t\t\t\t\t\t\tRH.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tBehavioral differentiation between itch and pain in mouse.\n\t\t\t\t\tPain.\n\t\t\t\t\t2008;\n\t\t\t\t\t139:\n\t\t\t\t\t681\u2013687.","DOI":"10.1016\/j.pain.2008.08.002"},{"key":"i1552-5783-60-5-1706-b28","doi-asserted-by":"crossref","unstructured":"Klein\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCarstens\n\t\t\t\t\t\t\tMI,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCarstens\n\t\t\t\t\t\t\tE.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tFacial injections of pruritogens or algogens elicit distinct behavior responses in rats and excite overlapping populations of primary sensory and trigeminal subnucleus caudalis neurons.\n\t\t\t\t\tJ Neurophysiol.\n\t\t\t\t\t2011;\n\t\t\t\t\t106:\n\t\t\t\t\t1078\u20131088.","DOI":"10.1152\/jn.00302.2011"},{"key":"i1552-5783-60-5-1706-b29","doi-asserted-by":"crossref","unstructured":"Dyhre\n\t\t\t\t\t\t\tH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLang\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWallin\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRenck\n\t\t\t\t\t\t\tH.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe duration of action of bupivacaine, levobupivacaine, ropivacaine and pethidine in peripheral nerve block in the rat.\n\t\t\t\t\tActa Anaesthesiol Scand.\n\t\t\t\t\t1997;\n\t\t\t\t\t41:\n\t\t\t\t\t1346\u20131352.","DOI":"10.1111\/j.1399-6576.1997.tb04656.x"},{"key":"i1552-5783-60-5-1706-b30","unstructured":"Gao\n\t\t\t\t\t\t\tYJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tJi\n\t\t\t\t\t\t\tRR.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tc-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?\n\t\t\t\t\tOpen Pain. J\n\t\t\t\t\t2009;\n\t\t\t\t\t2:\n\t\t\t\t\t11\u201317."},{"key":"i1552-5783-60-5-1706-b31","doi-asserted-by":"crossref","unstructured":"Hunt\n\t\t\t\t\t\t\tSP,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPini\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tEvan\n\t\t\t\t\t\t\tG.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tInduction of c-fos-like protein in spinal cord neurons following sensory stimulation.\n\t\t\t\t\tNature.\n\t\t\t\t\t1987;\n\t\t\t\t\t328:\n\t\t\t\t\t632\u2013634.","DOI":"10.1038\/328632a0"},{"key":"i1552-5783-60-5-1706-b32","doi-asserted-by":"crossref","unstructured":"Williams\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tEvan\n\t\t\t\t\t\t\tGI,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHunt\n\t\t\t\t\t\t\tSP.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tChanging patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat.\n\t\t\t\t\tNeuroscience.\n\t\t\t\t\t1990;\n\t\t\t\t\t36:\n\t\t\t\t\t73\u201381.","DOI":"10.1016\/0306-4522(90)90352-5"},{"key":"i1552-5783-60-5-1706-b33","doi-asserted-by":"crossref","unstructured":"Hitomi\n\t\t\t\t\t\t\tS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKross\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKurose\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPorreca\n\t\t\t\t\t\t\tF,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMeng\n\t\t\t\t\t\t\tID.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tActivation of dura-sensitive trigeminal neurons and increased c-Fos protein induced by morphine withdrawal in the rostral ventromedial medulla.\n\t\t\t\t\tCephalalgia.\n\t\t\t\t\t2017;\n\t\t\t\t\t37:\n\t\t\t\t\t407\u2013417.","DOI":"10.1177\/0333102416648655"},{"key":"i1552-5783-60-5-1706-b34","doi-asserted-by":"crossref","unstructured":"Robbins\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSchmitt\n\t\t\t\t\t\t\tD,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWinterson\n\t\t\t\t\t\t\tBJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMeng\n\t\t\t\t\t\t\tID.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tChronic morphine increases Fos-positive neurons after concurrent cornea and tail stimulation.\n\t\t\t\t\tHeadache.\n\t\t\t\t\t2012;\n\t\t\t\t\t52:\n\t\t\t\t\t262\u2013273.","DOI":"10.1111\/j.1526-4610.2011.01999.x"},{"key":"i1552-5783-60-5-1706-b35","doi-asserted-by":"crossref","unstructured":"Bereiter\n\t\t\t\t\t\t\tDA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tMorphine and somatostatin analogue reduce c-fos expression in trigeminal subnucleus caudalis produced by corneal stimulation in the rat.\n\t\t\t\t\tNeuroscience.\n\t\t\t\t\t1997;\n\t\t\t\t\t77:\n\t\t\t\t\t863\u2013874.","DOI":"10.1016\/S0306-4522(96)00541-6"},{"key":"i1552-5783-60-5-1706-b36","doi-asserted-by":"crossref","unstructured":"Kim\n\t\t\t\t\t\t\tMJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tShin\n\t\t\t\t\t\t\tHJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWon\n\t\t\t\t\t\t\tKA,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tProgesterone produces antinociceptive and neuroprotective effects in rats with microinjected lysophosphatidic acid in the trigeminal nerve root.\n\t\t\t\t\tMol Pain.\n\t\t\t\t\t2012;\n\t\t\t\t\t8:\n\t\t\t\t\t16.","DOI":"10.1186\/1744-8069-8-16"},{"key":"i1552-5783-60-5-1706-b37","doi-asserted-by":"crossref","unstructured":"Swerdlow\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tJones\n\t\t\t\t\t\t\tR.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe duration of action of bupivacaine, prilocaine and lignocaine.\n\t\t\t\t\tBr J Anaesth.\n\t\t\t\t\t1970;\n\t\t\t\t\t42:\n\t\t\t\t\t335\u2013339.","DOI":"10.1093\/bja\/42.4.335"},{"key":"i1552-5783-60-5-1706-b38","doi-asserted-by":"crossref","unstructured":"Roosterman\n\t\t\t\t\t\t\tD,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGoerge\n\t\t\t\t\t\t\tT,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSchneider\n\t\t\t\t\t\t\tSW,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBunnett\n\t\t\t\t\t\t\tNW,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSteinhoff\n\t\t\t\t\t\t\tM.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tNeuronal control of skin function: the skin as a neuroimmunoendocrine organ.\n\t\t\t\t\tPhysiol Rev.\n\t\t\t\t\t2006;\n\t\t\t\t\t86:\n\t\t\t\t\t1309\u20131379.","DOI":"10.1152\/physrev.00026.2005"},{"key":"i1552-5783-60-5-1706-b39","doi-asserted-by":"crossref","unstructured":"Dubner\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBennett\n\t\t\t\t\t\t\tGJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSpinal and trigeminal mechanisms of nociception.\n\t\t\t\t\tAnnu Rev Neurosci.\n\t\t\t\t\t1983;\n\t\t\t\t\t6:\n\t\t\t\t\t381\u2013418.","DOI":"10.1146\/annurev.ne.06.030183.002121"},{"key":"i1552-5783-60-5-1706-b40","doi-asserted-by":"crossref","unstructured":"Sessle\n\t\t\t\t\t\t\tBJ.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tNeural mechanisms and pathways in craniofacial pain.\n\t\t\t\t\tCan J Neurol Sci.\n\t\t\t\t\t1999;\n\t\t\t\t\t26\n\t\t\t\t\t(suppl 3):\n\t\t\t\t\tS7\u2013S11.","DOI":"10.1017\/S0317167100000135"},{"key":"i1552-5783-60-5-1706-b41","doi-asserted-by":"crossref","unstructured":"Robbins\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKurose\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWinterson\n\t\t\t\t\t\t\tBJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMeng\n\t\t\t\t\t\t\tID.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tMenthol activation of corneal cool cells induces TRPM8-mediated lacrimation but not nociceptive responses in rodents.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t2012;\n\t\t\t\t\t53:\n\t\t\t\t\t7034\u20137042.","DOI":"10.1167\/iovs.12-10025"},{"key":"i1552-5783-60-5-1706-b42","doi-asserted-by":"crossref","unstructured":"Marrone\n\t\t\t\t\t\t\tBL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGentry\n\t\t\t\t\t\t\tRT,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWade\n\t\t\t\t\t\t\tGN.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tGonadal hormones and body temperature in rats: effects of estrous cycles, castration and steroid replacement.\n\t\t\t\t\tPhysiol Behav.\n\t\t\t\t\t1976;\n\t\t\t\t\t17:\n\t\t\t\t\t419\u2013425.","DOI":"10.1016\/0031-9384(76)90101-3"},{"key":"i1552-5783-60-5-1706-b43","doi-asserted-by":"crossref","unstructured":"Nakayama\n\t\t\t\t\t\t\tT,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSuzuki\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tIshizuka\n\t\t\t\t\t\t\tN.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tAction of progesterone on preoptic thermosensitive neurones.\n\t\t\t\t\tNature.\n\t\t\t\t\t1975;\n\t\t\t\t\t258:\n\t\t\t\t\t80.","DOI":"10.1038\/258080a0"},{"key":"i1552-5783-60-5-1706-b44","doi-asserted-by":"crossref","unstructured":"Gordon\n\t\t\t\t\t\t\tCJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHeath\n\t\t\t\t\t\t\tJE.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tIntegration and central processing in temperature regulation.\n\t\t\t\t\tAnnu Rev Physiol.\n\t\t\t\t\t1986;\n\t\t\t\t\t48:\n\t\t\t\t\t595\u2013612.","DOI":"10.1146\/annurev.ph.48.030186.003115"},{"key":"i1552-5783-60-5-1706-b45","unstructured":"Boulant\n\t\t\t\t\t\t\tJA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tHypothalamic mechanisms in thermoregulation.\n\t\t\t\t\tFed Proc.\n\t\t\t\t\t1981;\n\t\t\t\t\t40:\n\t\t\t\t\t2843\u20132850."},{"key":"i1552-5783-60-5-1706-b46","doi-asserted-by":"crossref","unstructured":"Boulant\n\t\t\t\t\t\t\tJA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tRole of the preoptic-anterior hypothalamus in thermoregulation and fever.\n\t\t\t\t\tClin Infect Dis.\n\t\t\t\t\t2000;\n\t\t\t\t\t31\n\t\t\t\t\t(suppl 5):\n\t\t\t\t\tS157\u2013S161.","DOI":"10.1086\/317521"},{"key":"i1552-5783-60-5-1706-b47","doi-asserted-by":"crossref","unstructured":"Hirata\n\t\t\t\t\t\t\tH,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tOkamoto\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBereiter\n\t\t\t\t\t\t\tDA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tGABA(A) receptor activation modulates corneal unit activity in rostral and caudal portions of trigeminal subnucleus caudalis.\n\t\t\t\t\tJ Neurophysiol.\n\t\t\t\t\t2003;\n\t\t\t\t\t90:\n\t\t\t\t\t2837\u20132849.","DOI":"10.1152\/jn.00544.2003"},{"key":"i1552-5783-60-5-1706-b48","unstructured":"Pelletier\n\t\t\t\t\t\t\tG,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRen\n\t\t\t\t\t\t\tL.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tLocalization of sex steroid receptors in human skin.\n\t\t\t\t\tHistol Histopathol.\n\t\t\t\t\t2004;\n\t\t\t\t\t19:\n\t\t\t\t\t629\u2013636."},{"key":"i1552-5783-60-5-1706-b49","doi-asserted-by":"crossref","unstructured":"Singh\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSu\n\t\t\t\t\t\t\tC.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tProgesterone and neuroprotection.\n\t\t\t\t\tHorm Behav.\n\t\t\t\t\t2013;\n\t\t\t\t\t63:\n\t\t\t\t\t284\u2013290.","DOI":"10.1016\/j.yhbeh.2012.06.003"},{"key":"i1552-5783-60-5-1706-b50","doi-asserted-by":"crossref","unstructured":"Singh\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSu\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tNg\n\t\t\t\t\t\t\tS.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tNon-genomic mechanisms of progesterone action in the brain.\n\t\t\t\t\tFront Neurosci.\n\t\t\t\t\t2013;\n\t\t\t\t\t7:\n\t\t\t\t\t159.","DOI":"10.3389\/fnins.2013.00159"},{"key":"i1552-5783-60-5-1706-b51","doi-asserted-by":"crossref","unstructured":"Wang\n\t\t\t\t\t\t\tC,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLiu\n\t\t\t\t\t\t\tY,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tCao\n\t\t\t\t\t\t\tJM.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tG protein-coupled receptors: extranuclear mediators for the non-genomic actions of steroids.\n\t\t\t\t\tInt J Mol Sci.\n\t\t\t\t\t2014;\n\t\t\t\t\t15:\n\t\t\t\t\t15412\u201315425.","DOI":"10.3390\/ijms150915412"},{"key":"i1552-5783-60-5-1706-b52","doi-asserted-by":"crossref","unstructured":"Ryu\n\t\t\t\t\t\t\tCS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKlein\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tZanger\n\t\t\t\t\t\t\tUM.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tMembrane associated progesterone receptors: promiscuous proteins with pleiotropic functions - focus on interactions with cytochromes P450.\n\t\t\t\t\tFront Pharmacol.\n\t\t\t\t\t2017;\n\t\t\t\t\t8:\n\t\t\t\t\t159.","DOI":"10.3389\/fphar.2017.00159"},{"key":"i1552-5783-60-5-1706-b53","doi-asserted-by":"crossref","unstructured":"Petersen\n\t\t\t\t\t\t\tSL,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tIntlekofer\n\t\t\t\t\t\t\tKA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMoura-Conlon\n\t\t\t\t\t\t\tPJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBrewer\n\t\t\t\t\t\t\tDN,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDel Pino Sans\n\t\t\t\t\t\t\tJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLopez\n\t\t\t\t\t\t\tJA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tNovel progesterone receptors: neural localization and possible functions.\n\t\t\t\t\tFront Neurosci.\n\t\t\t\t\t2013;\n\t\t\t\t\t7:\n\t\t\t\t\t164.","DOI":"10.3389\/fnins.2013.00164"},{"key":"i1552-5783-60-5-1706-b54","doi-asserted-by":"crossref","unstructured":"Rahman\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tOkamoto\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tThompson\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tKatagiri\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tBereiter\n\t\t\t\t\t\t\tDA.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tSensitization of trigeminal brainstem pathways in a model for tear deficient dry eye.\n\t\t\t\t\tPain.\n\t\t\t\t\t2015;\n\t\t\t\t\t156:\n\t\t\t\t\t942\u2013950.","DOI":"10.1097\/j.pain.0000000000000135"},{"key":"i1552-5783-60-5-1706-b55","doi-asserted-by":"crossref","unstructured":"Bereiter\n\t\t\t\t\t\t\tDA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRahman\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tThompson\n\t\t\t\t\t\t\tR,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tStephenson\n\t\t\t\t\t\t\tP,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tSaito\n\t\t\t\t\t\t\tH.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tTRPV1 and TRPM8 channels and nocifensive behavior in a rat model for dry eye.\n\t\t\t\t\tInvest Ophthalmol Vis Sci.\n\t\t\t\t\t2018;\n\t\t\t\t\t59:\n\t\t\t\t\t3739\u20133746.","DOI":"10.1167\/iovs.18-24304"},{"key":"i1552-5783-60-5-1706-b56","doi-asserted-by":"crossref","unstructured":"Becker\n\t\t\t\t\t\t\tK,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tEder\n\t\t\t\t\t\t\tM,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tRanft\n\t\t\t\t\t\t\tA,\n\t\t\t\t\t\t\n\t\t\t\t\t\tet al.\n\t\t\t\t\t\n\t\t\t\t\tLow dose isoflurane exerts opposing effects on neuronal network excitability in neocortex and hippocampus.\n\t\t\t\t\tPLoS One.\n\t\t\t\t\t2012;\n\t\t\t\t\t7:\n\t\t\t\t\te39346.","DOI":"10.1371\/journal.pone.0039346"},{"key":"i1552-5783-60-5-1706-b57","doi-asserted-by":"crossref","unstructured":"Ma\n\t\t\t\t\t\t\tJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tShen\n\t\t\t\t\t\t\tB,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tStewart\n\t\t\t\t\t\t\tLS,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHerrick\n\t\t\t\t\t\t\tIA,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLeung\n\t\t\t\t\t\t\tLS.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tThe septohippocampal system participates in general anesthesia.\n\t\t\t\t\tJ Neurosci.\n\t\t\t\t\t2002;\n\t\t\t\t\t22:\n\t\t\t\t\tRC200.","DOI":"10.1523\/JNEUROSCI.22-02-j0004.2002"}],"container-title":["Investigative Opthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?articleid=2732111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:03Z","timestamp":1791927063000},"score":1,"resource":{"primary":{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.18-26049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,23]]},"references-count":57,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,4,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.18-26049","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4,23]]}}}