{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:58:55Z","timestamp":1791928735299,"version":"4.3.4"},"reference-count":64,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"13","license":[{"start":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T00:00:00Z","timestamp":1605744000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2020,11,19]]},"DOI":"10.1167\/iovs.61.13.25","type":"journal-article","created":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T13:36:42Z","timestamp":1605793002000},"page":"25","source":"Crossref","is-referenced-by-count":157,"title":["Increased Choroidal Blood Perfusion Can Inhibit Form Deprivation Myopia in Guinea Pigs"],"prefix":"10.1167","volume":"61","author":[{"given":"Xuan","family":"Zhou","sequence":"first","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoyun","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhong","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Lei","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Xiang","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renchang","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Qu","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangtian","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang, China"},{"name":"Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.preteyeres.2017.09.004","article-title":"The epidemics of myopia: Aetiology and prevention","volume":"62","author":"Morgan","year":"2018","journal-title":"Prog Retin Eye Res"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/cxo.2019.102.issue-1","article-title":"Myopia: is the nature-nurture debate finally over?","volume":"102","author":"Morgan","year":"2019","journal-title":"Clin Exp Optom"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmology"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1097\/ICL.0b013e31824ccbc3","article-title":"The prevalence and impact of high myopia","volume":"38","author":"Jones","year":"2012","journal-title":"Eye Contact Lens"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.ophtha.2018.10.029","article-title":"Potential Lost Productivity Resulting from the Global Burden of Myopia: Systematic Review, Meta-analysis, and Modeling","volume":"126","author":"Naidoo","year":"2019","journal-title":"Ophthalmology"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"431","DOI":"10.2471\/BLT.00.00000","article-title":"Potential lost productivity resulting from the global burden of uncorrected refractive error","volume":"87","author":"Smith","year":"2009","journal-title":"Bull World Health Organ"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S1350-9462(02)00063-0","article-title":"Role of the sclera in the development and pathological complications of myopia","volume":"22","author":"McBrien","year":"2003","journal-title":"Prog Retin Eye Res"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/bs.pmbts.2015.05.005","article-title":"Scleral Mechanisms Underlying Ocular Growth and Myopia","volume":"134","author":"Metlapally","year":"2015","journal-title":"Prog Mol Biol Transl Sci"},{"key":"bib9","first-page":"2179","article-title":"Structural and ultrastructural changes to the sclera in a mammalian model of high myopia","volume":"42","author":"McBrien","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib10","first-page":"183","article-title":"A study of biochemical and biomechanical qualities of normal and myopic eye sclera in humans of different age groups","volume":"7","author":"Avetisov","year":"1983","journal-title":"Metab Pediatr Syst Ophthalmol"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.neuron.2004.08.008","article-title":"Homeostasis of eye growth and the question of myopia","volume":"43","author":"Wallman","year":"2004","journal-title":"Neuron"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/j.tips.2019.09.009","article-title":"Pharmacogenomic Approach to Antimyopia Drug Development: Pathways Lead the Way","volume":"40","author":"Tkatchenko","year":"2019","journal-title":"Trends Pharmacol Sci"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"E7091","DOI":"10.1073\/pnas.1721443115","article-title":"Scleral hypoxia is a target for myopia control","volume":"115","author":"Wu","year":"2018","journal-title":"Proc Natl Acad Sci USA"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/S1350-9462(00)00027-6","article-title":"Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease","volume":"20","author":"Yu","year":"2001","journal-title":"Prog Retin Eye Res"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.preteyeres.2009.12.002","article-title":"The multifunctional choroid","volume":"29","author":"Nickla","year":"2010","journal-title":"Prog Retin Eye Res"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1006\/exer.2002.1142","article-title":"Temporal relationship of choroidal blood flow and thickness changes during recovery from form deprivation myopia in chicks","volume":"74","author":"Fitzgerald","year":"2002","journal-title":"Exp Eye Res"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1016\/0042-6989(94)00233-C","article-title":"Choroidal and scleral mechanisms of compensation for spectacle lenses in chicks","volume":"35","author":"Wildsoet","year":"1995","journal-title":"Vision Res"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.visres.2005.06.036","article-title":"Form-deprivation myopia in the guinea pig (Cavia porcellus)","volume":"46","author":"Howlett","year":"2006","journal-title":"Vision Res"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.visres.2008.10.008","article-title":"Spectacle lens compensation in the pigmented guinea pig","volume":"49","author":"Howlett","year":"2009","journal-title":"Vision Res"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0042-6989(94)E0049-Q","article-title":"Moving the retina: choroidal modulation of refractive state","volume":"35","author":"Wallman","year":"1995","journal-title":"Vision Res"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"3074","DOI":"10.1167\/iovs.18-26397","article-title":"Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia","volume":"60","author":"Zhang","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"309","DOI":"10.3341\/kjo.2015.29.5.309","article-title":"Choroidal Blood Flow Change in Eyes with High Myopia","volume":"29","author":"Yang","year":"2015","journal-title":"Korean J Ophthalmol"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1167\/iovs.16-21289","article-title":"Quantitative OCT Angiography of the Retinal Microvasculature and the Choriocapillaris in Myopic Eyes","volume":"58","author":"Al-Sheikh","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.12669\/pjms.336.13726","article-title":"Retinal and Choroidal Thickness in Patients with High Myopia without Maculopathy","volume":"33","author":"Teberik","year":"2017","journal-title":"Pak J Med Sci"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1097\/IAE.0b013e318242b990","article-title":"Choroidal thickness and visual acuity in highly myopic eyes","volume":"32","author":"Nishida","year":"2012","journal-title":"Retina"},{"key":"bib26","first-page":"2824","article-title":"Inhibition of experimental myopia by a dopamine agonist: different effectiveness between form deprivation and hyperopic defocus in guinea pigs","volume":"17","author":"Dong","year":"2011","journal-title":"Mol Vis"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"2306","DOI":"10.1167\/iovs.16-20402","article-title":"Bright Light Suppresses Form-Deprivation Myopia Development With Activation of Dopamine D1 Receptor Signaling in the ON Pathway in Retina","volume":"58","author":"Chen","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.exer.2006.09.019","article-title":"Effects of intravitreally and intraperitoneally injected atropine on two types of experimental myopia in chicken","volume":"84","author":"Diether","year":"2007","journal-title":"Exp Eye Res"},{"key":"bib29","first-page":"977","article-title":"Upregulation of regulator of G-protein signaling 2 in the sclera of a form deprivation myopic animal model","volume":"20","author":"Zou","year":"2014","journal-title":"Mol Vis"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"4319","DOI":"10.1167\/iovs.18-25258","article-title":"The Effects of High Lighting on the Development of Form-Deprivation Myopia in Guinea Pigs","volume":"60","author":"Zhang","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"5803","DOI":"10.1167\/iovs.17-22297","article-title":"Opposing Effects of PPARalpha Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs","volume":"59","author":"Pan","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1167\/iovs.16-20474","article-title":"Microglia Activation and Recruitment of Circulating Macrophages During Ischemic Experimental Branch Retinal Vein Occlusion","volume":"58","author":"Ebneter","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"e110906","DOI":"10.1371\/journal.pone.0110906","article-title":"Intermittent episodes of bright light suppress myopia in the chicken more than continuous bright light","volume":"9","author":"Lan","year":"2014","journal-title":"Plos One"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.preteyeres.2017.11.003","article-title":"Optical coherence tomography angiography","volume":"64","author":"Spaide","year":"2018","journal-title":"Prog Retin Eye Res"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1167\/iovs.08-2463","article-title":"Spontaneous axial myopia and emmetropization in a strain of wild-type guinea pig (Cavia porcellus)","volume":"50","author":"Jiang","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/0300-483X(79)90044-1","article-title":"Regional blood flow determinations in the rat during paraoxon-poisoning and treatment with atropine and obidoxime","volume":"12","author":"Vetterlein","year":"1979","journal-title":"Toxicology"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1167\/iovs.03-0997","article-title":"Dopaminergic vasodilation in the choroidal circulation by d1\/d5 receptor activation","volume":"45","author":"Reitsamer","year":"2004","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.cortex.2019.01.016","article-title":"Dopamine effects on frontal cortical blood flow and motor inhibition in Parkinson's disease","volume":"115","author":"Trujillo","year":"2019","journal-title":"Cortex"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41598-016-0002-7","article-title":"Nitric Oxide (NO) Mediates the Inhibition of Form-Deprivation Myopia by Atropine in Chicks","volume":"6","author":"Carr","year":"2016","journal-title":"Sci Rep"},{"key":"bib40","first-page":"925","article-title":"Nitric oxide and choroidal blood flow regulation","volume":"36","author":"Mann","year":"1995","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1006\/exer.1999.0753","article-title":"Characterization of alpha(1)-adrenoceptor subtypes in the eye","volume":"70","author":"Wikberg-Matsson","year":"2000","journal-title":"Exp Eye Res"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/0014-2999(93)90351-H","article-title":"Prazosin modulates the firing pattern of dopamine neurons in rat ventral tegmental area","volume":"233","author":"Grenhoff","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0014-2999(96)00315-9","article-title":"Prazosin inhibits MK-801-induced hyperlocomotion and dopamine release in the nucleus accumbens","volume":"309","author":"Mathe","year":"1996","journal-title":"Eur J Pharmacol"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/aos.2013.91.issue-2","article-title":"Measurement of choroidal perfusion and thickness following systemic sildenafil (Viagra((R)))","volume":"91","author":"Kim","year":"2013","journal-title":"Acta Ophthalmol"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"25","DOI":"10.3928\/23258160-20150101-04","article-title":"Choroidal thickness and choroidal blood flow after intravitreal bevacizumab injection in eyes with central serous chorioretinopathy","volume":"46","author":"Okamoto","year":"2015","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"9952","DOI":"10.1038\/s41598-017-09924-5","article-title":"The effect of topical administration of cyclopentolate on ocular biometry: An analysis for mouse and human models","volume":"7","author":"Huang","year":"2017","journal-title":"Sci Rep"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"6414","DOI":"10.1167\/iovs.15-17102","article-title":"Regional Changes in Choroidal Thickness Associated With Accommodation","volume":"56","author":"Woodman-Pieterse","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"2623","DOI":"10.1167\/iovs.17-22578","article-title":"Dopamine D1 Receptors Contribute Critically to the Apomorphine-Induced Inhibition of Form-Deprivation Myopia in Mice","volume":"59","author":"Huang","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.visres.2008.11.005","article-title":"Effects of unilateral topical atropine on binocular pupil responses and eye growth in mice","volume":"49","author":"Barathi","year":"2009","journal-title":"Vision Res"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/00006324-200402000-00012","article-title":"Inhibitory effects of apomorphine and atropine and their combination on myopia in chicks","volume":"81","author":"Schmid","year":"2004","journal-title":"Optometry Vision Sci"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"5247","DOI":"10.1167\/iovs.09-4689","article-title":"The effect of bright light on lens compensation in chicks","volume":"51","author":"Ashby","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1167\/iovs.11-8652","article-title":"Protective Effects of High Ambient Lighting on the Development of Form-Deprivation Myopia in Rhesus Monkeys","volume":"53","author":"Smith","year":"2012","journal-title":"Invest Ophth Vis Sci"},{"key":"bib53","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1016\/j.ophtha.2007.12.019","article-title":"Outdoor activity reduces the prevalence of myopia in children","volume":"115","author":"Rose","year":"2008","journal-title":"Ophthalmology"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"3524","DOI":"10.1167\/iovs.06-1118","article-title":"Parental history of myopia, sports and outdoor activities, and future myopia","volume":"48","author":"Jones","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.ophtha.2015.07.004","article-title":"Five-year clinical trial on atropine for the treatment of myopia 2: myopia control with atropine 0.01% eyedrops","volume":"123","author":"Chia","year":"2016","journal-title":"Ophthalmology"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.preteyeres.2017.06.003","article-title":"Dopamine signaling and myopia development: What are the key challenges","volume":"61","author":"Zhou","year":"2017","journal-title":"Prog Retin Eye Res"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/0014-4835(91)90027-C","article-title":"Muscarinic antagonist effects on experimental chick myopia","volume":"52","author":"Stone","year":"1991","journal-title":"Exp Eye Res"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"2778","DOI":"10.1167\/iovs.17-22562","article-title":"Myopia-inhibiting concentrations of muscarinic receptor antagonists block activation of alpha2a-adrenoceptors in vitro","volume":"59","author":"Carr","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib59","doi-asserted-by":"publisher","first-page":"4647","DOI":"10.1021\/pr500558y","article-title":"Involvement of GABA transporters in atropine-treated myopic retina as revealed by iTRAQ quantitative proteomics","volume":"13","author":"Barathi","year":"2014","journal-title":"J Proteome Res"},{"key":"bib60","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1111\/opo.12054","article-title":"Effects of muscarinic agents on chick choroids in intact eyes and eyecups: evidence for a muscarinic mechanism in choroidal thinning","volume":"33","author":"Nickla","year":"2013","journal-title":"Ophthalmic Physiol Opt"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"34936","DOI":"10.1038\/srep34936","article-title":"The effect of topical atropine on the choroidal thickness of healthy children","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci Rep"},{"key":"bib62","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1097\/OPX.0000000000000074","article-title":"Bright light induces choroidal thickening in chickens","volume":"90","author":"Lan","year":"2013","journal-title":"Optom Vis Sci"},{"key":"bib63","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1073\/pnas.86.2.704","article-title":"Retinal dopamine and form-deprivation myopia","volume":"86","author":"Stone","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"bib64","first-page":"1249","article-title":"Choroidal thickness changes during altered eye growth and refractive state in a primate","volume":"41","author":"Troilo","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Investigative Opthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2771973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:16Z","timestamp":1791927076000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2771973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,19]]},"references-count":64,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2020,11,2]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.61.13.25","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11,19]]}}}