{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:59:01Z","timestamp":1791928741388,"version":"4.3.4"},"reference-count":59,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"3","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2020,3,20]]},"DOI":"10.1167\/iovs.61.3.38","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T11:31:16Z","timestamp":1584703876000},"page":"38","source":"Crossref","is-referenced-by-count":37,"title":["Topographic Variations of Choroidal Thickness in Healthy Eyes on Swept-Source Optical Coherence Tomography"],"prefix":"10.1167","volume":"61","author":[{"given":"Sara","family":"Touhami","sequence":"first","affiliation":[{"name":"Ophthalmology Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 de Paris, Paris, France"},{"name":"Ophthalmology Department, Reference Center in Rare Diseases, DHU Sight Restore, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re, Sorbonne Universit\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Philippakis","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Mrejen","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, CHNO des Quinze-Vingts, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aude","family":"Couturier","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Casteran","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscille","family":"Levent","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramin","family":"Tadayoni","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Gaudric","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.ajo.2008.05.032","article-title":"Enhanced depth imaging spectral-domain optical coherence tomography","volume":"146","author":"Spaide","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"2562","DOI":"10.1016\/j.neurobiolaging.2014.05.003","article-title":"Choriocapillaris breakdown precedes retinal degeneration in age-related macular degeneration","volume":"35","author":"Biesemeier","year":"2014","journal-title":"Neurobiol Aging"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1038\/eye.2010.130","article-title":"Central serous chorioretinopathy: an update on pathogenesis and treatment","volume":"24","author":"Gemenetzi","year":"2010","journal-title":"Eye"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1167\/iovs.16-21289","article-title":"Quantitative OCT angiography of the retinal microvasculature and the choriocapillaris in myopic eyes","volume":"58","author":"Al-Sheikh","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"577","DOI":"10.5301\/ejo.5000936","article-title":"Correlation between choroidal thickness and degree of myopia assessed with enhanced depth imaging optical coherence tomography","volume":"27","author":"El-Shazly","year":"2017","journal-title":"Eur J Ophthalmol"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.ajo.2009.04.029","article-title":"Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes","volume":"148","author":"Fujiwara","year":"2009","journal-title":"Am J Ophthalmol"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1097\/IAE.0b013e318242b990","article-title":"Choroidal thickness and visual acuity in highly myopic eyes","volume":"32","author":"Nishida","year":"2012","journal-title":"Retina"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1097\/IAE.0b013e3181be0a83","article-title":"Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy","volume":"29","author":"Imamura","year":"2009","journal-title":"Retina"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1097\/IAE.0000000000000287","article-title":"Pachychoroid: an inherited condition?","volume":"35","author":"Lehmann","year":"2015","journal-title":"Retina"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.ajo.2018.09.034","article-title":"Predictive factors of response to mineralocorticoid receptor antagonists in non-resolving central serous chorioretinopathy","volume":"198","author":"Bousquet","year":"2019","journal-title":"Am J Ophthalmol"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1097\/IAE.0b013e3182953df4","article-title":"Pachychoroid pigment epitheliopathy","volume":"33","author":"Warrow","year":"2013","journal-title":"Retina"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1038\/s41433-018-0158-4","article-title":"Pachychoroid disease","volume":"33","author":"Cheung","year":"2019","journal-title":"Eye"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"e0133080","DOI":"10.1371\/journal.pone.0133080","article-title":"Characterization of choroidal layers in normal aging eyes using enface swept-source optical coherence tomography","volume":"10","author":"Adhi","year":"2015","journal-title":"PLoS One"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1016\/j.ajo.2014.02.034","article-title":"Choroidal analysis in healthy eyes using swept-source optical coherence tomography compared to spectral domain optical coherence tomography","volume":"157","author":"Adhi","year":"2014","journal-title":"Am J Ophthalmol"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1016\/j.ophtha.2013.01.066","article-title":"Analysis of choroidal morphologic features and vasculature in healthy eyes using spectral-domain optical coherence tomography","volume":"120","author":"Branchini","year":"2013","journal-title":"Ophthalmology"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"2329","DOI":"10.1097\/IAE.0000000000001097","article-title":"Optical coherence tomography evidence on the correlation of choroidal thickness and age with vascularized retinal layers in normal eyes","volume":"36","author":"Abdolrahimzadeh","year":"2016","journal-title":"Retina"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"2572","DOI":"10.1016\/j.ophtha.2012.06.065","article-title":"Choroidal volume variations with age, axial length, and sex in healthy subjects: a three-dimensional analysis","volume":"119","author":"Barteselli","year":"2012","journal-title":"Ophthalmology"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3928\/23258160-20150101-03","article-title":"Optical coherence tomography measurements of choroidal thickness in healthy eyes: correlation with age and axial length","volume":"46","author":"Abbey","year":"2015","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1186\/s12886-016-0361-7","article-title":"Interocular symmetry of the peripapillary choroidal thickness and retinal nerve fibre layer thickness in healthy adults with isometropia","volume":"16","author":"Yang","year":"2016","journal-title":"BMC Ophthalmol"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"5260","DOI":"10.1167\/iovs.10-5196","article-title":"Three-dimensional 1060-nm OCT: choroidal thickness maps in normal subjects and improved posterior segment visualization in cataract patients","volume":"51","author":"Esmaeelpour","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1167\/iovs.11-8771","article-title":"Topographic variation and interocular symmetry of macular choroidal thickness using enhanced depth imaging optical coherence tomography","volume":"53","author":"Chen","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.1118\/1.4943382","article-title":"Choroidal vasculature characteristics based choroid segmentation for enhanced depth imaging optical coherence tomography images","volume":"43","author":"Chen","year":"2016","journal-title":"Med Phys"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.cmpb.2017.11.002","article-title":"Automated choroid segmentation of three-dimensional SD-OCT images by incorporating EDI-OCT images","volume":"158","author":"Chen","year":"2018","journal-title":"Comput Methods Programs Biomed"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ajo.2016.07.006","article-title":"Factors affecting choroidal vascular density in normal eyes: quantification using en face swept-source optical coherence tomography","volume":"170","author":"Fujiwara","year":"2016","journal-title":"Am J Ophthalmol"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1007\/s00417-017-3723-9","article-title":"Mapping diurnal changes in choroidal, Haller's and Sattler's layer thickness using 3-dimensional 1060-nm optical coherence tomography","volume":"255","author":"Gabriel","year":"2017","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"4971","DOI":"10.1167\/iovs.11-7729","article-title":"Macular choroidal thickness and volume in normal subjects measured by swept-source optical coherence tomography","volume":"52","author":"Hirata","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"2173","DOI":"10.1167\/iovs.09-4383","article-title":"Choroidal thickness in healthy Japanese subjects","volume":"51","author":"Ikuno","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1016\/j.ajo.2008.12.008","article-title":"A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes","volume":"147","author":"Margolis","year":"2009","journal-title":"Am J Ophthalmol"},{"key":"bib29","first-page":"360","article-title":"Diurnal variations in luminal and stromal areas of choroid in normal eyes","volume":"101","author":"Kinoshita","year":"2017","journal-title":"Br J Ophthalmol"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"7630","DOI":"10.1167\/iovs.13-13135","article-title":"Comparisons of choroidal thickness of normal eyes obtained by two different spectral-domain OCT instruments and one swept-source OCT instrument","volume":"54","author":"Matsuo","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"639160","DOI":"10.1155\/2014\/639160","article-title":"Correlation of choroidal thickness and volume measurements with axial length and age using swept source optical coherence tomography and optical low-coherence reflectometry","volume":"2014","author":"Michalewski","year":"2014","journal-title":"BioMed Res Int"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"6284","DOI":"10.1167\/iovs.15-16670","article-title":"Combined 60\u00b0 wide-field choroidal thickness maps and high-definition en face vasculature visualization using swept-source megahertz OCT at 1050 nm","volume":"56","author":"Mohler","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1186\/s12886-016-0314-1","article-title":"Macular choroidal thickness in normal Egyptians measured by swept source optical coherence tomography","volume":"16","author":"Moussa","year":"2016","journal-title":"BMC Ophthalmol"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"7019","DOI":"10.1167\/iovs.11-8046","article-title":"Spatial distribution of posterior pole choroidal thickness by spectral domain optical coherence tomography","volume":"52","author":"Ouyang","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"2267","DOI":"10.1167\/iovs.10-6024","article-title":"Repeatability of manual subfoveal choroidal thickness measurements in healthy subjects using the technique of enhanced depth imaging optical coherence tomography","volume":"52","author":"Rahman","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"1872","DOI":"10.1167\/iovs.14-16179","article-title":"Peripapillary choroidal thickness variation with age and race in normal eyes","volume":"56","author":"Rhodes","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib37","first-page":"97","article-title":"Choroidal thickness of the papillomacular region in young healthy individuals","volume":"232","author":"Rossou","year":"2014","journal-title":"Int J Ophthalmol"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"3532","DOI":"10.1167\/iovs.14-13868","article-title":"Macular choroidal thickness profile in a healthy population measured by swept-source optical coherence tomography","volume":"55","author":"Ruiz-Medrano","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.ajo.2015.05.027","article-title":"Morphologic features of the choroidoscleral interface in a healthy population using swept-source optical coherence tomography","volume":"160","author":"Ruiz-Medrano","year":"2015","journal-title":"Am J Ophthalmol"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1016\/j.ajo.2014.05.035","article-title":"Choroidal thickness and volume in healthy young white adults and the relationships between them and axial length, ammetropy and sex","volume":"158","author":"Sanchez-Cano","year":"2014","journal-title":"Am J Ophthalmol"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1016\/j.ophtha.2011.10.029","article-title":"Choroidal thickness and volume mapping by a six radial scan protocol on spectral-domain optical coherence tomography","volume":"119","author":"Shin","year":"2012","journal-title":"Ophthalmology"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"255","DOI":"10.3341\/kjo.2012.26.4.255","article-title":"Measurement of choroidal thickness in normal eyes using 3D OCT-1000 spectral domain optical coherence tomography","volume":"26","author":"Shin","year":"2012","journal-title":"Korean J Ophthalmol"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1167\/iovs.11-8782","article-title":"Diurnal variation of choroidal thickness in normal, healthy subjects measured by spectral domain optical coherence tomography","volume":"53","author":"Tan","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1186\/s12886-015-0110-3","article-title":"Swept-source optical coherence tomography imaging of macular retinal and choroidal structures in healthy eyes","volume":"15","author":"Wang","year":"2015","journal-title":"BMC Ophthalmol"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.survophthal.2012.12.001","article-title":"Optical coherence tomography: imaging of the choroid and beyond","volume":"58","author":"Mrejen","year":"2013","journal-title":"Surv Ophthalmol"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1097\/IAE.0000000000000742","article-title":"En face imaging of pachychoroid spectrum disorders with swept-source optical coherence tomography","volume":"36","author":"Dansingani","year":"2016","journal-title":"Retina"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"5827","DOI":"10.1167\/iovs.17-22581","article-title":"Choroidal thickness in and outside of vascular arcade in healthy eyes using spectral-domain optical coherence tomography","volume":"58","author":"Park","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1136\/bjophthalmol-2015-307985","article-title":"Choroidal thickness maps from spectral domain and swept source optical coherence tomography: algorithmic versus ground truth annotation","volume":"100","author":"Philip","year":"2016","journal-title":"Br J Ophthalmol"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.ophtha.2012.07.048","article-title":"Subfoveal choroidal thickness: the Beijing Eye Study","volume":"120","author":"Wei","year":"2013","journal-title":"Ophthalmology"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1097\/IAE.0000000000002022","article-title":"Repeatability of choroidal thickness measurements assessed with swept-source optical coherence tomography in healthy and diabetic individuals","volume":"39","author":"Abad\u00eda","year":"2019","journal-title":"Retina"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1007\/s00417-011-1708-7","article-title":"Choroidal thickness measurement in healthy Japanese subjects by three-dimensional high-penetration optical coherence tomography","volume":"249","author":"Agawa","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"e709","DOI":"10.1111\/aos.13084","article-title":"Choroidal thickness does not predict visual acuity in young high myopes","volume":"94","author":"Gupta","year":"2016","journal-title":"Acta Ophthalmol"},{"key":"bib53","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.ajo.2010.04.018","article-title":"Choroidal thickness in normal eyes measured using Cirrus HD optical coherence tomography","volume":"150","author":"Manjunath","year":"2010","journal-title":"Am J Ophthalmol"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.ophtha.2003.06.009","article-title":"Asymmetry of choroidal venous vascular patterns in the human eye","volume":"111","author":"Mori","year":"2004","journal-title":"Ophthalmology"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.oret.2017.05.013","article-title":"Dilatation of asymmetric vortex vein in central serous chorioretinopathy","volume":"2","author":"Hiroe","year":"2018","journal-title":"Ophthalmol Retina"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"3563","DOI":"10.1167\/iovs.18-26381","article-title":"New insights on choroidal vascularity: a comprehensive topographic approach","volume":"60","author":"Goud","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"4896","DOI":"10.1167\/iovs.18-25018","article-title":"Changes in stromal and luminal areas of the choroid in pachychoroid diseases: insights into the pathophysiology of pachychoroid diseases","volume":"59","author":"Lee","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/09273948.2019.1678650","article-title":"Choroidal vascular changes in multiple evanescent white dot syndrome","volume":"7","author":"Pellegrini","year":"2019","journal-title":"Ocul Immunol Inflamm"},{"key":"bib59","doi-asserted-by":"crossref","DOI":"10.1097\/IAE.0000000000002585","article-title":"Use of choroidal vascularity index for choroidal structural evaluation in central serous chorioretinopathy with choroidal neovascularization","author":"Kim","year":"2019","journal-title":"Retina"}],"container-title":["Investigative Opthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2763505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:18Z","timestamp":1791927078000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2763505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,20]]},"references-count":59,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3,9]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.61.3.38","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3,20]]}}}