{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:58:08Z","timestamp":1792648688889,"version":"4.5.0"},"reference-count":83,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"3","license":[{"start":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T00:00:00Z","timestamp":1584316800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2020,3,16]]},"DOI":"10.1167\/iovs.61.3.9","type":"journal-article","created":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T10:31:42Z","timestamp":1584354702000},"page":"9","source":"Crossref","is-referenced-by-count":43,"title":["Measurement of Diurnal Variation in Rod Outer Segment Length In Vivo in Mice With the OCT Optoretinogram"],"prefix":"10.1167","volume":"61","author":[{"given":"Pengfei","family":"Zhang","sequence":"first","affiliation":[{"name":"UC Davis Eye-Pod, Department of Cell Biology and Human Anatomy, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley","family":"Shibata","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Human Anatomy, School of Medicine, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Peinado","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Human Anatomy, School of Medicine, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Zawadzki","sequence":"additional","affiliation":[{"name":"UC Davis Eye-Pod, Department of Cell Biology and Human Anatomy, University of California Davis, Davis, California, United States"},{"name":"Vision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology & Vision Science, University of California Davis, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"FitzGerald","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Human Anatomy, School of Medicine, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Edward N.","family":"Pugh","sequence":"additional","affiliation":[{"name":"UC Davis Eye-Pod, Department of Cell Biology and Human Anatomy, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1002\/(ISSN)1096-9861","article-title":"Rods and cones in the mouse retina. 1. Structural analysis using light and electron microscop","volume":"188","author":"Carter-Dawson","year":"1979","journal-title":"J Comp Neurol."},{"key":"bib2","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1002\/(ISSN)1096-9861","article-title":"Human photoreceptor topography","volume":"292","author":"Curcio","year":"1990","journal-title":"J Comp Neurol."},{"key":"bib3","doi-asserted-by":"publisher","first-page":"e0125631","DOI":"10.1371\/journal.pone.0125631","article-title":"A comparison of some organizational characteristics of the mouse central retina and the human macula","volume":"10","author":"Volland","year":"2015","journal-title":"PLOS ONE"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"e1000377","DOI":"10.1371\/journal.pgen.1000377","article-title":"Accumulation of rhodopsin in late endosomes triggers photoreceptor cell degeneration","volume":"5","author":"Chinchore","year":"2009","journal-title":"PLOS Genet."},{"key":"bib5","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1038\/343364a0","article-title":"A point mutation of the rhodopsin gene in one form of retinitis pigmentosa","volume":"343","author":"Dryja","year":"1990","journal-title":"Nature"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/ng0692-209","article-title":"A null mutation in the rhodopsin gene causes rod photoreceptor dysfunction and autosomal recessive retinitis pigmentosa","volume":"1","author":"Rosenfeld","year":"1992","journal-title":"Nat Genet."},{"key":"bib7","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1146\/annurev.physiol.64.082701.102229","article-title":"G-proteins and phototransduction","volume":"64","author":"Arshavsky","year":"2002","journal-title":"Annu Rev Physiol."},{"key":"bib8","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/S0022-5320(71)90014-1","article-title":"Shedding of discs from rod outer segments in the rhesus monkey","volume":"34","author":"Young","year":"1971","journal-title":"J Ultrastruct Res"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1083\/jcb.49.2.303","article-title":"The renewal of rod and cone outer segments in the rhesus monkey","volume":"49","author":"Young","year":"1971","journal-title":"J Cell Biol"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1083\/jcb.33.1.61","article-title":"The renewal of photoreceptor cell outer segments","volume":"33","author":"Young","year":"1967","journal-title":"J Cell Biol."},{"key":"bib11","doi-asserted-by":"publisher","first-page":"5257","DOI":"10.1364\/OE.18.005257","article-title":"Imaging outer segment renewal in living human cone photoreceptors","volume":"18","author":"Jonnal","year":"2010","journal-title":"Optics Exp."},{"key":"bib12","doi-asserted-by":"publisher","first-page":"4554","DOI":"10.1364\/BOE.7.004554","article-title":"Photoreceptor disc shedding in the living human eye","volume":"7","author":"Kocaoglu","year":"2016","journal-title":"Biomed Optics Exp."},{"key":"bib14","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1038\/39068","article-title":"Prolonged photoresponses in transgenic mouse rods lacking arrestin","volume":"389","author":"Xu","year":"1997","journal-title":"Nature"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1083\/jcb.58.3.650","article-title":"Kinetics of rod outer segment renewal in the developing mouse retina","volume":"58","author":"LaVail","year":"1973","journal-title":"J Cell Biol."},{"key":"bib16","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/0006-8993(86)90550-0","article-title":"Circadian rhythm in the light response of rat retinal disk-shedding and autophagy","volume":"369","author":"Reme\u00b4","year":"1986","journal-title":"Brain Res."},{"key":"bib17","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1126\/science.6828862","article-title":"Methoxyindoles and photoreceptor metabolism: activation of rod shedding","volume":"219","author":"Besharse","year":"1983","journal-title":"Science"},{"key":"bib18","first-page":"695","article-title":"The sensitivity of rat rod outer segment disc shedding to light","volume":"22","author":"Goldman","year":"1982","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib19","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1085\/jgp.79.5.775","article-title":"Effects of cyclic adenosine 3',5'-monophosphate on photoreceptor disc shedding and retinomotor movement. Inhibition of rod shedding and stimulation of cone elongation","volume":"79","author":"Besharse","year":"1982","journal-title":"J Gen Physiol."},{"key":"bib20","first-page":"1268","article-title":"Evidence for both local and central regulation of rat rod outer segment disc shedding","volume":"19","author":"Teirstein","year":"1980","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib21","first-page":"407","article-title":"Circadian nature of rod outer segment disc shedding in the rat","volume":"19","author":"LaVail","year":"1980","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib22","first-page":"1257","article-title":"The role of ambient lighting in circadian disc shedding in the rod outer segment of the rat retina","volume":"19","author":"Goldman","year":"1980","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib23","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1126\/science.982063","article-title":"Rod outer segment disk shedding in rat retina: relationship to cyclic lighting","volume":"194","author":"LaVail","year":"1976","journal-title":"Science"},{"key":"bib24","first-page":"117","article-title":"Mammalian cones: disc shedding, phagocytosis, and renewal","volume":"17","author":"Anderson","year":"1978","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib25","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1083\/jcb.87.2.451","article-title":"Membrane assembly in retinal photoreceptors I. Freeze-fracture analysis of cytoplasmic vesicles in relationship to disc assembly","volume":"87","author":"Besharse","year":"1980","journal-title":"J Cell Biol."},{"key":"bib26","doi-asserted-by":"publisher","first-page":"1982","DOI":"10.1002\/dvdy.v237:8","article-title":"Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors","volume":"237","author":"Insinna","year":"2008","journal-title":"Dev Dyn"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1111\/cge.2009.76.issue-2","article-title":"Development and disease of the photoreceptor cilium","volume":"76","author":"Ramamurthy","year":"2009","journal-title":"Clin Genet"},{"key":"bib28","first-page":"8","article-title":"Phagocytosis of retinal rod and cone photoreceptors","volume":"25","author":"Kevany","year":"2010","journal-title":"Physiology (Bethesda)"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.exer.2014.01.010","article-title":"Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture","volume":"126","author":"Mazzoni","year":"2014","journal-title":"Exp Eye Res"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.preteyeres.2016.05.003","article-title":"Molecular basis for photoreceptor outer segment architecture","volume":"55","author":"Goldberg","year":"2016","journal-title":"Prog Retin Eye Res"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1083\/jcb.201608081","article-title":"Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release","volume":"216","author":"Salinas","year":"2017","journal-title":"J Cell Biol"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"13087","DOI":"10.1073\/pnas.1906421116","article-title":"PRCD is essential for high-fidelity photoreceptor disc formation","volume":"116","author":"Spencer","year":"2019","journal-title":"Proc Natl Acad Sci USA"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"5066","DOI":"10.1073\/pnas.0506997103","article-title":"Optophysiology: depth-resolved probing of retinal physiology with functional ultrahigh-resolution optical coherence tomography","volume":"103","author":"Bizheva","year":"2006","journal-title":"Proc Natl Acad Sci USA."},{"key":"bib34","doi-asserted-by":"publisher","first-page":"2308","DOI":"10.1364\/OL.31.002308","article-title":"In vivo measurement of retinal physiology with high-speed ultrahigh-resolution optical coherence tomography","volume":"31","author":"Srinivasan","year":"2006","journal-title":"Optics Lett."},{"key":"bib35","first-page":"1","article-title":"Functional optical coherence tomography enables in vivo physiological assessment of retinal rod and cone photoreceptors","volume":"5","author":"Zhang","year":"2015","journal-title":"Scient Rep."},{"key":"bib36","doi-asserted-by":"publisher","first-page":"OCT105","DOI":"10.1167\/iovs.15-18539","article-title":"Light-induced thickening of photoreceptor outer segment layer detected by ultra-high resolution OCT imaging","volume":"57","author":"Li","year":"2016","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib37","doi-asserted-by":"publisher","first-page":"1982","DOI":"10.1002\/dvdy.v237:8","article-title":"Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors","volume":"237","author":"Insinna","year":"2008","journal-title":"Dev Dyn"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1126\/science.1957169","article-title":"Optical coherence tomography","volume":"254","author":"Huang","year":"1991","journal-title":"Science"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1117\/1.1482379","article-title":"In vivo human retinal imaging by Fourier domain optical coherence tomography","volume":"7","author":"Wojtkowski","year":"2002","journal-title":"J Biomed Optics"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1088\/0034-4885\/66\/2\/204","article-title":"Optical coherence tomography - principles and applications","volume":"66","author":"Fercher","year":"2003","journal-title":"Rep Progr Phys."},{"key":"bib41","doi-asserted-by":"publisher","first-page":"e7507","DOI":"10.1371\/journal.pone.0007507","article-title":"Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography","volume":"4","author":"Fischer","year":"2009","journal-title":"Plos One"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"E2937","DOI":"10.1073\/pnas.1620572114","article-title":"In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors","volume":"114","author":"Zhang","year":"2017","journal-title":"Proc Natl Acad Sci USA."},{"key":"bib43","doi-asserted-by":"publisher","first-page":"4632","DOI":"10.1167\/iovs.17-22171","article-title":"Photoreceptor layer thickness changes during dark adaptation observed with ultrahigh-resolution optical coherence tomography","volume":"58","author":"Lu","year":"2017","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib44","doi-asserted-by":"publisher","first-page":"7951","DOI":"10.1073\/pnas.1816360116","article-title":"Cone photoreceptor classification in the living human eye from photostimulation-induced phase dynamics","volume":"116","author":"Zhang","year":"2019","journal-title":"Proc Natl Acad Sci USA.s"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"13138","DOI":"10.1073\/pnas.1606428113","article-title":"In vivo optical imaging of physiological responses to photostimulation in human photoreceptors","volume":"113","author":"Hillmann","year":"2016","journal-title":"Proc Natl Acad Sci USA."},{"key":"bib47","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1126\/science.102035","article-title":"Rapid light-induced changes in near infrared transmission of rods in Bufo marinus","volume":"202","author":"Harary","year":"1978","journal-title":"Science"},{"key":"bib48","first-page":"4","article-title":"Optoretinography: optical measurements of human cone and rod photoreceptor responses to light","volume":"10","author":"Azimipour","year":"2019","journal-title":"bioRxiv"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1364\/OPTICA.6.000300","article-title":"Functional retinal imaging using adaptive optics swept-source OCT at 1.6MHz","volume":"6","author":"Azimipour","year":"2019","journal-title":"Optica"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"126005","DOI":"10.1117\/1.JBO.20.12.126005","article-title":"In vivo wide-field multispectral scanning laser ophthalmoscopy-optical coherence tomography mouse retinal imager: longitudinal imaging of ganglion cells, microglia, and Muller glia, and mapping of the mouse retinal and choroidal vasculature","volume":"20","author":"Zhang","year":"2015","journal-title":"J Biomed Optics"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"3650","DOI":"10.1167\/iovs.16-19393","article-title":"The photosensitivity of rhodopsin bleaching and light-induced increases of fundus reflectance in mice measured in vivo with scanning laser ophthalmoscopy","volume":"57","author":"Zhang","year":"2016","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib52","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.exer.2018.03.027","article-title":"Effect of a contact lens on mouse retinal in vivo imaging: effective focal length changes and monochromatic aberrations","volume":"172","author":"Zhang","year":"2018","journal-title":"Exp Eye Res."},{"key":"bib53","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1258\/la.2010.009085","article-title":"Isoflurane and sevoflurane provide equally effective anaesthesia in laboratory mice","volume":"44","author":"Cesarovic","year":"2010","journal-title":"Lab Animals"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"9880","DOI":"10.1021\/bi0505363","article-title":"Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye","volume":"44","author":"Lyubarsky","year":"2005","journal-title":"Biochemistry"},{"key":"bib55","doi-asserted-by":"crossref","first-page":"93070H","DOI":"10.1117\/12.2080468","article-title":"Multispectral scanning laser ophthalmoscopy combined with optical coherence tomography for simultaneous in vivo mouse retinal imaging","volume":"9307","author":"Zhang","year":"2015","journal-title":"Proc. SPIE BiOS"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"2156","DOI":"10.1364\/OPEX.12.002156","article-title":"Ultrahigh resolution Fourier domain optical coherence tomography","volume":"12","author":"Leitgeb","year":"2004","journal-title":"Optics Exp."},{"key":"bib57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1117\/1.JBO.24.6.066011","article-title":"Directional optical coherence tomography reveals melanin concentration-dependent scattering properties of retinal pigment epithelium","volume":"24","author":"Meleppat","year":"2019","journal-title":"J Biomed Optics"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"3598","DOI":"10.1364\/OE.11.003598","article-title":"High-speed spectral-domain optical coherence tomography at 1.3 mum wavelength","volume":"11","author":"Yun","year":"2003","journal-title":"Optics Exp."},{"key":"bib59","first-page":"428","article-title":"An alternative means of retaining ocular structure and improving immunoreactivity for light microscopy studies","volume":"21","author":"Sun","year":"2015","journal-title":"Mol Vision"},{"key":"bib61","first-page":"1019","article-title":"Turnover of mouse photoreceptor outer segments in constant light and darkness","volume":"18","author":"Besharse","year":"1979","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib62","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1084\/jem.20041447","article-title":"Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin","volume":"200","author":"Nandrot","year":"2004","journal-title":"J Exp Med"},{"key":"bib63","first-page":"1019","article-title":"Turnover of mouse photoreceptor outer segments in constant light and darkness","volume":"18","author":"Besharse","year":"1979","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib64","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1016\/S0006-3495(02)73911-8","article-title":"Dynamic behavior of rod photoreceptor disks","volume":"83","author":"Chen","year":"2002","journal-title":"Biophys J"},{"issue":"9","key":"bib65","first-page":"1294","article-title":"Light induced water movement in the outer retina investigated by Optical Coherence Tomography","volume":"60","author":"Zawadzki","year":"2019","journal-title":"IOVS"},{"key":"bib66","doi-asserted-by":"publisher","first-page":"2803","DOI":"10.1167\/iovs.03-0001","article-title":"Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement","volume":"44","author":"Stamer","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib67","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1364\/BOE.2.000100","article-title":"Temporal changes of human cone photoreceptors observed in vivo with SLO\/OCT","volume":"2","author":"Pircher","year":"2011","journal-title":"Biomed Optics Exp."},{"key":"bib68","doi-asserted-by":"publisher","first-page":"6497","DOI":"10.1167\/iovs.11-7403","article-title":"Diurnal variation of retina thickness measured with time domain and spectral domain optical coherence tomography in healthy subjects","volume":"52","author":"Jo","year":"2011","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib69","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1097\/OPX.0b013e3182501917","article-title":"Diurnal variation of retinal thickness with spectral domain OCT","volume":"89","author":"Read","year":"2012","journal-title":"Optom Vision Sci."},{"key":"bib70","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1159\/000375538","article-title":"Diurnal variation in choroidal and retinal thickness of the early treatment of diabetic retinopathy study macular subfields determined using swept-source optical coherence tomography","volume":"233","author":"Han","year":"2015","journal-title":"Ophthalmologica"},{"key":"bib71","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.1167\/iovs.19-26711","article-title":"Ocular and systemic diurnal rhythms in emmetropic and myopic adults","volume":"60","author":"Burfield","year":"2019","journal-title":"Invest Ophthalmol Vis Sci."},{"key":"bib72","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1017\/S095252380118209X","article-title":"Rod photopigment deficits in albinos are specific to mammals and arise during retinal development","volume":"18","author":"Grant","year":"2001","journal-title":"Visual Neurosci."},{"key":"bib73","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1523\/JNEUROSCI.21-01-00053.2001","article-title":"The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration","volume":"21","author":"Wenzel","year":"2001","journal-title":"J Neurosci"},{"key":"bib74","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/S0166-2236(96)10080-1","article-title":"The albino retina: an abnormality that provides insight into normal retinal development","volume":"20","author":"Jeffery","year":"1997","journal-title":"Trends Neurosci"},{"key":"bib75","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1364\/BOE.3.000715","article-title":"Adaptive optics retinal imaging in the living mouse eye","volume":"3","author":"Geng","year":"2012","journal-title":"Biomed Opt Exp."},{"key":"bib76","doi-asserted-by":"publisher","first-page":"4757","DOI":"10.1364\/BOE.10.004757","article-title":"Adaptive optics in the mouse eye: wavefront sensing based vs. image-guided aberration correction","volume":"10","author":"Wahl","year":"2019","journal-title":"Biomed Opt Exp."},{"key":"bib77","first-page":"08","article-title":"Towards in vivo imaging of the mouse cone photoreceptors","volume":"10858","author":"Zhang","year":"2019","journal-title":"Proc. SPIE BiOS"},{"key":"bib78","first-page":"27","article-title":"Adaptive optics with combined optical coherence tomography and scanning laser ophthalmoscopy for in vivo mouse retina imaging","volume":"10474","author":"Zhang","year":"2018","journal-title":"Proc. SPIE BIOS"},{"key":"bib79","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1117\/1.NPh.6.4.041105","article-title":"Temporal speckle-averaging of optical coherence tomography volumes for cellular resolution neuronal and vascular retinal imaging","volume":"6","author":"Zhang","year":"2019","journal-title":"Neurophotonics"},{"key":"bib80","doi-asserted-by":"publisher","first-page":"16603","DOI":"10.1073\/pnas.1903336116","article-title":"In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury","volume":"116","author":"Miller","year":"2019","journal-title":"Proc Natl Acad Sci USA."},{"key":"bib81","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1364\/BOE.10.000552","article-title":"Aperture phase modulation with adaptive optics: a novel approach for speckle reduction and structure extraction in optical coherence tomography","volume":"10","author":"Zhang","year":"2019","journal-title":"Biomed Opt Exp."},{"key":"bib82","doi-asserted-by":"publisher","first-page":"14017","DOI":"10.1038\/s41598-018-32336-y","article-title":"A high content, small molecule screen identifies candidate molecular pathways that regulate rod photoreceptor outer segment renewal","volume":"8","author":"Campbell","year":"2018","journal-title":"Sci Rep"},{"key":"bib83","first-page":"8","article-title":"Phagocytosis of retinal rod and cone photoreceptors","volume":"25","author":"Kevany","year":"2010","journal-title":"Physiology (Bethesda, Md)"},{"key":"bib13","first-page":"8","article-title":"Tracking dynamics of photoreceptor disc shedding with adaptive optics-optical coherence tomography","volume-title":"SPIE BiOS","author":"Zhang","year":"2017"},{"key":"bib46","article-title":"The Optoretinogram at 38","volume-title":"Optical Society of America Fall Vision Meeting: Symposium Honoring D I A MacLeod","author":"Mulligan","year":"2018"},{"key":"bib60","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/0-387-32442-9_72","article-title":"The retinal pigment epithelium apical microvilli and retinal function","volume-title":"Retinal Degenerative Diseases","author":"Bonilha","year":"2006"}],"container-title":["Investigative Opthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2763121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:22Z","timestamp":1791927082000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2763121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,16]]},"references-count":83,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3,9]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.61.3.9","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3,16]]}}}