{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:59:43Z","timestamp":1791928783151,"version":"4.3.4"},"reference-count":39,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"1","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2021,1,21]]},"DOI":"10.1167\/iovs.62.1.22","type":"journal-article","created":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T10:34:28Z","timestamp":1611225268000},"page":"22","source":"Crossref","is-referenced-by-count":17,"title":["The Macular Choriocapillaris Flow in Glaucoma and Within-Day Fluctuations: An Optical Coherence Tomography Angiography Study"],"prefix":"10.1167","volume":"62","author":[{"given":"Paolo","family":"Milani","sequence":"first","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara Enrica","family":"Urbini","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ennio","family":"Bulone","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"Nava","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Visintin","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Cremonesi","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Scotti","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"},{"name":"Translational Medicine Department, Eastern Piedmont University, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulvio","family":"Bergamini","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"2","key":"bib1","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1097\/ICU.0000000000000554","article-title":"Optical coherence tomography angiography in glaucoma","volume":"30","author":"Bojikian","year":"2019","journal-title":"Curr Opin Ophthalmol"},{"issue":"12","key":"bib2","doi-asserted-by":"publisher","first-page":"e81499","DOI":"10.1371\/journal.pone.0081499","article-title":"Choriocapillaris and choroidal microvasculature imaging with ultrahigh speed OCT angiography","volume":"8","author":"Choi","year":"2013","journal-title":"PLoS One"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.preteyeres.2017.11.003","article-title":"Optical coherence tomography angiography","volume":"64","author":"Spaide","year":"2018","journal-title":"Prog Retin Eye Res"},{"issue":"9","key":"bib4","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1001\/jamaophthalmol.2015.2225","article-title":"Optical coherence tomography angiography of the peripapillary retina in glaucoma","volume":"133","author":"Liu","year":"2015","journal-title":"JAMA Ophthalmol"},{"issue":"9","key":"bib5","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1007\/s00417-015-3095-y","article-title":"Correlation between optic disc perfusion and glaucomatous severity in patients with open-angle glaucoma: an optical coherence tomography angiography study","volume":"253","author":"Wang","year":"2015","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"9","key":"bib6","doi-asserted-by":"publisher","first-page":"OCT475","DOI":"10.1167\/iovs.15-18909","article-title":"Peripapillary retinal nerve fiber layer vascular microcirculation in glaucoma using optical coherence tomography-based microangiography","volume":"57","author":"Chen","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"11","key":"bib7","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1080\/02713683.2017.1337157","article-title":"Glaucoma diagnostic ability of the optical coherence tomography angiography vessel density parameters","volume":"42","author":"Chung","year":"2017","journal-title":"Curr Eye Res"},{"issue":"8","key":"bib8","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1007\/s00417-018-3965-1","article-title":"OCTA vessel density changes in the macular zone in glaucomatous eyes","volume":"256","author":"Lommatzsch","year":"2018","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"2","key":"bib9","doi-asserted-by":"publisher","first-page":"e199","DOI":"10.1111\/aos.2019.97.issue-2","article-title":"Optical coherence tomography angiography analysis of macular flow density in glaucoma","volume":"97","author":"Kromer","year":"2019","journal-title":"Acta Ophthalmol"},{"issue":"1","key":"bib10","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1097\/IJG.0000000000001125","article-title":"Optical coherence tomography angiography of optic disc and macula vessel density in glaucoma and healthy eyes","volume":"28","author":"Yip","year":"2019","journal-title":"J Glaucoma"},{"issue":"4","key":"bib11","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1097\/IJG.0000000000001463","article-title":"Optical coherence tomography angiography in glaucoma","volume":"29","author":"Rao","year":"2020","journal-title":"J Glaucoma"},{"issue":"12","key":"bib12","doi-asserted-by":"publisher","first-page":"2509","DOI":"10.1016\/j.ophtha.2016.09.002","article-title":"Deep retinal layer microvasculature dropout detected by the optical coherence tomography angiography in glaucoma","volume":"123","author":"Suh","year":"2016","journal-title":"Ophthalmology"},{"issue":"3","key":"bib13","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1167\/iovs.17-21440","article-title":"Underlying microstructure of parapapillary deep-layer capillary dropout identified by optical coherence tomography angiography","volume":"58","author":"Lee","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"7419470","DOI":"10.1155\/2019\/7419470","article-title":"Early macular angiography among patients with glaucoma, ocular hypertension, and normal subjects","volume":"2019","author":"Chao","year":"2019","journal-title":"J Ophthalmol"},{"issue":"6","key":"bib15","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1097\/IJG.0000000000001242","article-title":"Quantitative analysis of retinal and choroidal vascular parameters in patients with low tension glaucoma","volume":"28","author":"Tepelus","year":"2019","journal-title":"J Glaucoma"},{"issue":"1","key":"bib16","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1097\/00061198-199702000-00006","article-title":"Widespread choroidal insufficiency in primary open-angle glaucoma","volume":"6","author":"Yin","year":"1997","journal-title":"J Glaucoma"},{"issue":"4","key":"bib17","first-page":"603","article-title":"Comparison of peripapillary and macular choroidal thickness and ganglion cell complex thickness in glaucomatous and healthy eyes","volume":"12","author":"Park","year":"2019","journal-title":"Int J Ophthalmol"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s40942-018-0140-0","article-title":"Diurnal variation of choriocapillaris vessel flow density in normal subjects measured using optical coherence tomography angiography","volume":"4","author":"Sarwar","year":"2018","journal-title":"Int J Retina Vitreous"},{"issue":"8","key":"bib19","doi-asserted-by":"publisher","first-page":"e1062","DOI":"10.1111\/aos.v97.8","article-title":"Evaluating diurnal changes in choroidal sublayer perfusion using optical coherence tomography angiography","volume":"97","author":"Siegfried","year":"2019","journal-title":"Acta Ophthalmol"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.ajo.2016.07.015","article-title":"Quantitative optical coherence tomography angiography of radial peripapillary capillaries in glaucoma, glaucoma suspect, and normal eyes","volume":"170","author":"Mammo","year":"2016","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"bib21","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1097\/IJG.0000000000000649","article-title":"Radial peripapillary capillary density measurement using optical coherence tomography angiography in early glaucoma","volume":"26","author":"Mansoori","year":"2017","journal-title":"J Glaucoma"},{"issue":"5","key":"bib22","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.ophtha.2017.01.004","article-title":"Peripapillary and macular vessel density in patients with glaucoma and single-hemifield visual field defect","volume":"124","author":"Yarmohammadi","year":"2017","journal-title":"Ophthalmology"},{"issue":"9","key":"bib23","doi-asserted-by":"publisher","first-page":"e0204183","DOI":"10.1371\/journal.pone.0204183","article-title":"Peripapillary and macular choroidal area in patients with normal-tension glaucoma","volume":"13","author":"Kojima","year":"2018","journal-title":"PLoS One"},{"issue":"6","key":"bib24","doi-asserted-by":"publisher","first-page":"e0157333","DOI":"10.1371\/journal.pone.0157333","article-title":"Assessment of open-angle glaucoma peripapillary and macular choroidal thickness using swept-source optical coherence tomography (SS-OCT)","volume":"11","author":"Song","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"bib25","doi-asserted-by":"publisher","first-page":"e110265","DOI":"10.1371\/journal.pone.0110265","article-title":"The whole macular choroidal thickness in subjects with primary open angle glaucoma","volume":"9","author":"Nakakura","year":"2014","journal-title":"PLoS One"},{"issue":"5","key":"bib26","doi-asserted-by":"publisher","first-page":"548","DOI":"10.5301\/ejo.5000926","article-title":"Choroidal thickness and structural glaucoma parameters in glaucomatous, preperimetric glaucomatous, and healthy eyes using swept-source OCT","volume":"27","author":"Akil","year":"2017","journal-title":"Eur J Ophthalmol"},{"issue":"9","key":"bib27","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1136\/bjo.81.9.735","article-title":"Choroidal haemodynamics in glaucoma","volume":"81","author":"Duijm","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"bib28","article-title":"Diurnal measurements of macular thickness and vessel density on OCT angiography in healthy eyes and those with ocular hypertension and glaucoma [published online ahead of print, June 16, 2020]","author":"Milani","journal-title":"J Glaucoma"},{"issue":"4","key":"bib29","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1097\/IJG.0000000000000914","article-title":"Diurnal variations of peripapillary and macular vessel density in glaucomatous eyes using optical coherence tomography angiography","volume":"27","author":"Mansouri","year":"2018","journal-title":"J Glaucoma"},{"issue":"12","key":"bib30","doi-asserted-by":"publisher","first-page":"6652","DOI":"10.1167\/iovs.10-5490","article-title":"Retrobulbar blood flow velocities in open angle glaucoma and their association with mean arterial blood pressure","volume":"51","author":"Garh\u00f6fer","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib31","doi-asserted-by":"publisher","first-page":"e36","DOI":"10.1111\/aos.13850","article-title":"Optic nerve head blood flow regulation during changes in arterial blood pressure in patients with primary open-angle glaucoma","volume":"97","author":"Bata","year":"2019","journal-title":"Acta Ophthalmol"},{"issue":"4","key":"bib32","doi-asserted-by":"publisher","first-page":"2300","DOI":"10.1167\/iovs.11-8383","article-title":"Circadian changes in subfoveal choroidal thickness and the relationship with circulatory factors in healthy subjects","volume":"53","author":"Usui","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"bib33","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1007\/s00417-017-3723-9","article-title":"Mapping diurnal changes in choroidal, Haller's and Sattler's layer thickness using 3-dimensional 1060-nm optical coherence tomography","volume":"255","author":"Gabriel","year":"2017","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"4","key":"bib34","doi-asserted-by":"publisher","first-page":"206","DOI":"10.3928\/23258160-20200326-01","article-title":"Pachychoroid disease","volume":"51","author":"Freund","year":"2020","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"issue":"3","key":"bib35","first-page":"360","article-title":"Diurnal variations in luminal and stromal areas of choroid in normal eyes","volume":"101","author":"Kinoshita","year":"2017","journal-title":"Br J Ophthalmol"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.preteyeres.2017.12.001","article-title":"Neural control of choroidal blood flow","volume":"64","author":"Reiner","year":"2018","journal-title":"Prog Retin Eye Res"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"e844","DOI":"10.1111\/aos.v97.6","article-title":"Diurnal variations in flow density measured using optical coherence tomography angiography and the impact of heart rate, mean arterial pressure and intraocular pressure on flow density in primary open-angle glaucoma patients","volume":"97","author":"M\u00fcller","year":"2019","journal-title":"Acta Ophthalmol"},{"key":"bib38","article-title":"Plexus-specific retinal vascular anatomy and pathologies as seen by projection-resolved optical coherence tomographic angiography [published online ahead of print July 24, 2020]","author":"Hormel","journal-title":"Prog Retin Eye Res"},{"issue":"11","key":"bib39","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1016\/j.ophtha.2017.06.002","article-title":"Projection-resolved optical coherence tomography angiography of macular retinal circulation in glaucoma","volume":"124","author":"Takusagawa","year":"2017","journal-title":"Ophthalmology"}],"container-title":["Investigative Opthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2772211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:26Z","timestamp":1791927086000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2772211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,21]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1,4]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.62.1.22","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1,21]]}}}