{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:59:45Z","timestamp":1791928785355,"version":"4.3.4"},"reference-count":44,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"13","license":[{"start":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T00:00:00Z","timestamp":1635292800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2021,10,27]]},"DOI":"10.1167\/iovs.62.13.27","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T11:32:07Z","timestamp":1635334327000},"page":"27","source":"Crossref","is-referenced-by-count":4,"title":["Comparative Topographical Analysis of Choroidal Microvascular Dropout Between Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy"],"prefix":"10.1167","volume":"62","author":[{"given":"Eun Jung","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Joo","family":"Kee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Ah","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Chul","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changwon","family":"Kee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"5673","DOI":"10.1167\/iovs.17-22604","article-title":"Parapapillary deep-layer microvasculature dropout in primary open-angle glaucoma eyes with a parapapillary gamma-zone","volume":"58","author":"Lee","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"2509","DOI":"10.1016\/j.ophtha.2016.09.002","article-title":"Deep retinal layer microvasculature dropout detected by the optical coherence tomography angiography in glaucoma","volume":"123","author":"Suh","year":"2016","journal-title":"Ophthalmology"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1167\/iovs.61.2.36","article-title":"Microstructure of nonjuxtapapillary microvasculature dropout in healthy myopic eyes","volume":"61","author":"Kim","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1016\/j.ophtha.2018.01.016","article-title":"Choroidal microvasculature dropout is associated with progressive retinal nerve fiber layer thinning in glaucoma with disc hemorrhage","volume":"125","author":"Park","year":"2018","journal-title":"Ophthalmology"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1001\/jamaophthalmol.2019.1212","article-title":"Evaluation of parapapillary choroidal microvasculature dropout and progressive retinal nerve fiber layer thinning in patients with glaucoma","volume":"137","author":"Kim","year":"2019","journal-title":"JAMA Ophthalmol"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1167\/iovs.18-26298","article-title":"Greater severity of glaucomatous damage in eyes with than without choroidal microvasculature dropout in open-angle glaucoma","volume":"60","author":"Jo","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"e0233270","DOI":"10.1371\/journal.pone.0233270","article-title":"Hemisphere opposite to vascular trunk deviation is earlier affected by glaucomatous damage in myopic high-tension glaucoma","volume":"15","author":"Lee","year":"2020","journal-title":"PLoS One"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.ajo.2020.03.009","article-title":"Choroidal microvasculature dropout is associated with generalized choroidal vessel loss within the beta-parapapillary atrophy in glaucoma","volume":"215","author":"Jo","year":"2020","journal-title":"Am J Ophthalmol"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"2695","DOI":"10.1167\/iovs.17-21791","article-title":"The characteristics of deep optic nerve head morphology in myopic normal tension glaucoma","volume":"58","author":"Han","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib10","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1167\/iovs.17-23046","article-title":"Deep-layer microvasculature dropout by optical coherence tomography angiography and microstructure of parapapillary atrophy","volume":"59","author":"Suh","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.1097\/IJG.0000000000001688","article-title":"Progression of parapapillary choroidal microvascular dropout after disc hemorrhage in glaucoma patients: 2 case reports","volume":"30","author":"Lee","year":"2021","journal-title":"J Glaucoma"},{"issue":"12","key":"bib12","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1016\/j.ophtha.2020.06.001","article-title":"Glaucoma-like parapapillary choroidal microvasculature dropout in patients with compressive optic neuropathy","volume":"127","author":"Lee","year":"2020","journal-title":"Ophthalmology"},{"key":"bib13","article-title":"Parapapillary deep-layer microvasculature dropout is only found near the retinal nerve fibre layer defect location in open-angle glaucoma [published online March 19, 2021]","author":"Son","journal-title":"Acta Ophthalmol"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1136\/bjophthalmol-2020-316169","article-title":"Progressive retinal nerve fibre layer thinning and choroidal microvasculature dropout at the location of disc haemorrhage in glaucoma","volume":"105","author":"Kim","year":"2021","journal-title":"Br J Ophthalmol"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/0002-9394(76)90414-1","article-title":"Reevaluation of the optic disk vasculature","volume":"82","author":"Anderson","year":"1976","journal-title":"Am J Ophthalmol"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/0002-9394(76)90489-X","article-title":"Histologic studies of the vasculature of the anterior optic nerve","volume":"82","author":"Lieberman","year":"1976","journal-title":"Am J Ophthalmol"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.ajo.2019.02.023","article-title":"Border tissue morphology is spatially associated with focal lamina cribrosa defect and deep-layer microvasculature dropout in open-angle glaucoma","volume":"203","author":"Han","year":"2019","journal-title":"Am J Ophthalmol"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/S0161-6420(02)01297-6","article-title":"Misleading statistical calculations in far-advanced glaucomatous visual field loss","volume":"110","author":"Blumenthal","year":"2003","journal-title":"Ophthalmology"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.ajo.2018.01.035","article-title":"Choroidal microvasculature dropout is associated with parafoveal visual field defects in glaucoma","volume":"188","author":"Kwon","year":"2018","journal-title":"Am J Ophthalmol"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1016\/j.ophtha.2017.03.039","article-title":"Parapapillary choroidal microvasculature dropout in glaucoma: a comparison between optical coherence tomography angiography and indocyanine green angiography","volume":"124","author":"Lee","year":"2017","journal-title":"Ophthalmology"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/j.ophtha.2017.10.036","article-title":"Central visual field damage and parapapillary choroidal microvasculature dropout in primary open-angle glaucoma","volume":"125","author":"Lee","year":"2018","journal-title":"Ophthalmology"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/S1350-9462(02)00008-3","article-title":"The impact of ocular blood flow in glaucoma","volume":"21","author":"Flammer","year":"2002","journal-title":"Prog Retin Eye Res"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/S1350-9462(01)00004-0","article-title":"The blood supply of the optic nerve head and the evaluation of it\u2014myth and reality","volume":"20","author":"Hayreh","year":"2001","journal-title":"Prog Retin Eye Res"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.ajo.2010.01.018","article-title":"Blood Flow in Glaucoma Discussion. Blood pressure, perfusion pressure, and glaucoma","volume":"149","author":"Caprioli","year":"2010","journal-title":"Am J Ophthalmol"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/S1350-9462(97)00009-8","article-title":"Vascular pathogenesis of normal-tension glaucoma: a possible pathogenetic factor, other than intraocular pressure, of glaucomatous optic neuropathy","volume":"17","author":"Yamamoto","year":"1998","journal-title":"Prog Retin Eye Res"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/S0161-6420(99)00037-8","article-title":"Peripapillary chorioretinal atrophy: Bruch's membrane changes and photoreceptor loss","volume":"107","author":"Curcio","year":"2000","journal-title":"Ophthalmology"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1167\/iovs.17-21440","article-title":"Underlying microstructure of parapapillary deep-layer capillary dropout identified by optical coherence tomography angiography","volume":"58","author":"Lee","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.1007\/s00417-019-04403-1","article-title":"Choriocapillaris flow impairment predicts the development and enlargement of drusen","volume":"257","author":"Nassisi","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1097\/ICB.0000000000000512","article-title":"Serpiginous choroiditis imaged by optical coherence tomography angiography","volume":"12","author":"El Ameen","year":"2018","journal-title":"Retin Cases Brief Rep"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"AMD122","DOI":"10.1167\/iovs.18-23819","article-title":"Choroidal flow signal in late-onset Stargardt disease and age-related macular degeneration: an OCT-angiography study","volume":"59","author":"Muller","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"308","DOI":"10.3129\/i08-042","article-title":"Vascular anatomy of the optic nerve head","volume":"43","author":"Mackenzie","year":"2008","journal-title":"Can J Ophthalmol"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1001\/archopht.1987.01060050099046","article-title":"Angioarchitecture of the human choroid","volume":"105","author":"Yoneya","year":"1987","journal-title":"Arch Ophthalmol"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1136\/bjo.59.11.631","article-title":"Segmental nature of the choroidal vasculature","volume":"59","author":"Hayreh","year":"1975","journal-title":"Br J Ophthalmol"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1136\/bjo.87.2.189","article-title":"Optic disc morphology in south India: the Vellore Eye Study","volume":"87","author":"Jonas","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1038\/sj.eye.6702601","article-title":"Peripapillary atrophy in elderly Chinese in rural and urban Beijing","volume":"22","author":"Wang","year":"2008","journal-title":"Eye (Lond)"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1016\/S0161-6420(99)90457-8","article-title":"Determinants of optic disc characteristics in a general population: the Rotterdam Study","volume":"106","author":"Ramrattan","year":"1999","journal-title":"Ophthalmology"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"e701","DOI":"10.1111\/aos.13702","article-title":"Beta-peripapillary atrophy of the optic disc and its determinants in Japanese eyes: a population-based study","volume":"96","author":"Mataki","year":"2018","journal-title":"Acta Ophthalmol"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1001\/jama.2014.3192","article-title":"The pathophysiology and treatment of glaucoma: a review","volume":"311","author":"Weinreb","year":"2014","journal-title":"JAMA"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/bs.pbr.2015.04.003","article-title":"The contribution of the sclera and lamina cribrosa to the pathogenesis of glaucoma: diagnostic and treatment implications","volume":"220","author":"Quigley","year":"2015","journal-title":"Prog Brain Res"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.preteyeres.2008.11.002","article-title":"Ischemic optic neuropathy","volume":"28","author":"Hayreh","year":"2009","journal-title":"Prog Retin Eye Res"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"e0189237","DOI":"10.1371\/journal.pone.0189237","article-title":"Pattern of peripapillary capillary density loss in ischemic optic neuropathy compared to that in primary open-angle glaucoma","volume":"13","author":"Fard","year":"2018","journal-title":"PLoS One"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1097\/WNO.0000000000000775","article-title":"Optical coherence tomography angiography of a pale optic disc in demyelinating optic neuritis and ischemic optic neuropathy","volume":"39","author":"Fard","year":"2019","journal-title":"J Neuroophthalmol"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"5188","DOI":"10.1167\/iovs.17-22593","article-title":"Wide-field OCT angiography investigation of the relationship between radial peripapillary capillary plexus density and nerve fiber layer thickness","volume":"58","author":"Jia","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1167\/iovs.61.3.35","article-title":"Automated evaluation of parapapillary choroidal microvasculature in ischemic optic neuropathy and open angle glaucoma","volume":"61","author":"Aghsaei Fard","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Investigative Opthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2778027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:27Z","timestamp":1791927087000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2778027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,27]]},"references-count":44,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2021,10,4]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.62.13.27","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10,27]]}}}