{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:59:17Z","timestamp":1791928757905,"version":"4.3.4"},"reference-count":74,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"14","license":[{"start":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T00:00:00Z","timestamp":1637107200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2021,11,17]]},"DOI":"10.1167\/iovs.62.14.17","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T12:07:42Z","timestamp":1637150862000},"page":"17","source":"Crossref","is-referenced-by-count":51,"title":["Lowering Intraocular Pressure: A Potential Approach for Controlling High Myopia Progression"],"prefix":"10.1167","volume":"62","author":[{"given":"Peiyuan","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shida","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoming","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengbin","family":"Lin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhe","family":"Song","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuozhang","family":"Li","sequence":"additional","affiliation":[{"name":"Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tin","family":"Aung","sequence":"additional","affiliation":[{"name":"Singapore National Eye Center, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiulan","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the GSHM study group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"3","key":"bib1","doi-asserted-by":"publisher","first-page":"M20","DOI":"10.1167\/iovs.18-25957","article-title":"IMI\u2014defining and classifying myopia: a proposed set of standards for clinical and epidemiologic studies","volume":"60","author":"Flitcroft","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"bib2","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1097\/IAE.0000000000001489","article-title":"Overview of the complications of high myopia","volume":"37","author":"Ikuno","year":"2017","journal-title":"Retina"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.preteyeres.2015.12.001","article-title":"Updates of pathologic myopia","volume":"52","author":"Ohno-Matsui","year":"2016","journal-title":"Prog Retin Eye Res"},{"issue":"9827","key":"bib4","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1016\/S0140-6736(12)60272-4","volume":"379","author":"Morgan","year":"2012","journal-title":"Lancet"},{"issue":"6","key":"bib5","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1097\/APO.0000000000000234","article-title":"Epidemiology of pathologic myopia in Asia and worldwide","volume":"5","author":"Wong","year":"2016","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1186\/s40662-020-00210-6","article-title":"Advances in myopia research anatomical findings in highly myopic eyes","volume":"7","author":"Jonas","year":"2020","journal-title":"Eye Vis (Lond)"},{"issue":"5","key":"bib7","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/01.APO.0000578944.25956.8b","article-title":"Myopia: anatomic changes and consequences for its etiology","volume":"8","author":"Jonas","year":"2019","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"issue":"3","key":"bib8","doi-asserted-by":"publisher","first-page":"M89","DOI":"10.1167\/iovs.18-25965","article-title":"IMI\u2014myopia genetics report","volume":"60","author":"Tedja","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"bib9","doi-asserted-by":"publisher","first-page":"1612","DOI":"10.1016\/j.ophtha.2020.05.014","article-title":"Genome-wide association study in asians identifies novel loci for high myopia and highlights a nervous system role in its pathogenesis","volume":"127","author":"Meguro","year":"2020","journal-title":"Ophthalmology"},{"issue":"3","key":"bib10","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S1350-9462(02)00063-0","article-title":"Role of the sclera in the development and pathological complications of myopia","volume":"22","author":"McBrien","year":"2003","journal-title":"Prog Retin Eye Res"},{"issue":"6","key":"bib11","doi-asserted-by":"crossref","first-page":"e709","DOI":"10.1111\/aos.14372","article-title":"Relationships among retinal\/choroidal thickness, retinal microvascular network and visual field in high myopia","volume":"98","author":"Wu","year":"2020","journal-title":"Acta Ophthalmol"},{"issue":"10","key":"bib12","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1016\/S0161-6420(99)90416-5","article-title":"The relationship between glaucoma and myopia: the Blue Mountains Eye Study","volume":"106","author":"Mitchell","year":"1999","journal-title":"Ophthalmology"},{"issue":"1","key":"bib13","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0161-6420(02)01260-5","article-title":"Refractive errors, intraocular pressure, and glaucoma in a white population","volume":"110","author":"Wong","year":"2003","journal-title":"Ophthalmology"},{"issue":"9","key":"bib14","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1016\/j.ophtha.2010.01.035","article-title":"Los Angeles Latino Eye Study Group. Ocular biometry and open-angle glaucoma: the Los Angeles Latino Eye Study","volume":"117","author":"Kuzin","year":"2010","journal-title":"Ophthalmology"},{"issue":"2","key":"bib15","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.ophtha.2012.07.065","article-title":"Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study","volume":"120","author":"Pan","year":"2013","journal-title":"Ophthalmology"},{"issue":"1","key":"bib16","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.ophtha.2015.07.002","article-title":"The association of refractive error with glaucoma in a multiethnic population","volume":"123","author":"Shen","year":"2016","journal-title":"Ophthalmology"},{"issue":"6","key":"bib17","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1001\/archopht.120.6.701","article-title":"The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma","volume":"120","author":"Kass","year":"2002","journal-title":"Arch Ophthalmol"},{"issue":"8","key":"bib18","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1097\/IJG.0b013e3181d12dae","article-title":"Axial length does not correlate with degree of visual field loss in myopic Chinese individuals with glaucomatous appearing optic nerves","volume":"19","author":"Chao","year":"2010","journal-title":"J Glaucoma"},{"issue":"10","key":"bib19","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1016\/j.ophtha.2011.03.012","article-title":"Myopia as a risk factor for open-angle glaucoma: a systematic review and meta-analysis","volume":"118","author":"Marcus","year":"2011","journal-title":"Ophthalmology"},{"issue":"12","key":"bib20","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1097\/OPX.0b013e318230f559","article-title":"Intraocular pressure, ethnicity, and refractive error","volume":"88","author":"Manny","year":"2011","journal-title":"Optom Vis Sci"},{"issue":"4","key":"bib21","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1038\/s41588-020-0599-0","article-title":"Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia","volume":"52","author":"Hysi","year":"2020","journal-title":"Nat Genet"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1136\/bjophthalmol-2018-312085","article-title":"Relationship between vessel density and visual field sensitivity in glaucomatous eyes with high myopia","volume":"103","author":"Shin","year":"2018","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"bib23","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1097\/ICU.0000000000000548","article-title":"Myopic optic disc changes and its role in glaucoma","volume":"30","author":"Tan","year":"2019","journal-title":"Curr Opin Ophthalmol"},{"issue":"5","key":"bib24","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1006\/exer.2000.0834","article-title":"Timolol lowers intraocular pressure but does not inhibit the development of experimental myopia in chick","volume":"70","author":"Schmid","year":"2000","journal-title":"Exp Eye Res"},{"issue":"1","key":"bib25","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1186\/s12886-020-01610-x","article-title":"Lens-induced myopization and intraocular pressure in young guinea pigs","volume":"20","author":"Dong","year":"2020","journal-title":"BMC Ophthalmol"},{"issue":"6","key":"bib26","doi-asserted-by":"publisher","first-page":"2644","DOI":"10.1167\/iovs.17-22890","article-title":"Effects of topical latanoprost on intraocular pressure and myopia progression in young guinea pigs","volume":"59","author":"El-Nimri","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"107740","DOI":"10.1016\/j.exer.2019.107740","article-title":"Effect of chronic topical latanoprost on the sclera and lamina cribrosa of form-deprived myopic Guinea pigs","volume":"186","author":"El-Nimri","year":"2019","journal-title":"Exp Eye Res"},{"issue":"3","key":"bib28","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1111\/bcpt.2018.123.issue-3","article-title":"Prostaglandin F2a receptor modulation affects eye development in guinea pigs","volume":"123","author":"Yang","year":"2018","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"bib29","first-page":"785","article-title":"Alpha-adrenergic agonist brimonidine control of experimentally induced myopia in guinea pigs: a pilot study","volume":"23","author":"Liu","year":"2017","journal-title":"Mol Vis"},{"issue":"1","key":"bib30","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s40662-021-00248-0","article-title":"Intravitreal brimonidine inhibits form-deprivation myopia in guinea pigs","volume":"8","author":"Yang","year":"2021","journal-title":"Eye Vis (Lond)"},{"issue":"8","key":"bib31","doi-asserted-by":"publisher","first-page":"5121","DOI":"10.1167\/iovs.11-7364","article-title":"Diurnal variations in axial length, choroidal thickness, intraocular pressure, and ocular biometrics","volume":"52","author":"Chakraborty","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib32","doi-asserted-by":"publisher","first-page":"17821","DOI":"10.1038\/s41598-020-74126-5","article-title":"The relationship between axial length, age and intraocular pressure in children with primary congenital glaucoma","volume":"10","author":"Al-Obaida","year":"2020","journal-title":"SCI REP-UK Sci Rep"},{"issue":"12","key":"bib33","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1007\/s00417-001-0377-3","article-title":"Correlation of postoperative axial length growth and intraocular pressure in congenital glaucoma\u2014a retrospective study in trabeculotomy and goniotomy","volume":"239","author":"Kiefer","year":"2001","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"6","key":"bib34","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1016\/S0002-9394(01)01183-7","article-title":"Serial axial length measurements in congenital glaucoma","volume":"132","author":"Law","year":"2001","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"bib35","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1097\/OPX.0b013e3181622633","article-title":"IOP, myopic progression and axial length in a COMET subgroup","volume":"85","author":"Manny","year":"2008","journal-title":"Optom Vis Sci"},{"issue":"1","key":"bib36","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1136\/bjo.88.1.5","article-title":"Intraocular pressure associations with refractive error and axial length in children","volume":"88","author":"Lee","year":"2004","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"bib37","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1136\/bjophthalmol-2017-311831","article-title":"Intraocular pressure and myopia progression in Chinese children: the Anyang Childhood Eye Study","volume":"103","author":"Li","year":"2019","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"bib38","doi-asserted-by":"publisher","first-page":"554","DOI":"10.18240\/ijo","article-title":"Distribution of IOP and its relationship with refractive error and other factors: the Anyang University Students Eye Study","volume":"14","author":"Ma","year":"2021","journal-title":"Int J Ophthalmol"},{"issue":"4","key":"bib39","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/j.ophtha.2015.11.031","article-title":"Associations with intraocular pressure in a large cohort: results from the UK Biobank","volume":"123","author":"Chan","year":"2016","journal-title":"Ophthalmology"},{"issue":"5","key":"bib40","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1038\/sj.eye.6702709","article-title":"Effects of change in intraocular pressure on axial eye length and lens position","volume":"22","author":"Leydolt","year":"2008","journal-title":"Eye (Lond)"},{"issue":"1","key":"bib41","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1046\/j.1475-1313.2003.00158.x","article-title":"The relationship between intraocular pressure and refractive error adjusting for age and central corneal thickness","volume":"24","author":"Nomura","year":"2004","journal-title":"Ophthalmic Physiol Opt"},{"issue":"2","key":"bib42","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.ajo.2010.03.009","article-title":"Intraocular pressure and related systemic and ocular biometric factors in a population-based study in Japan: the Kumejima study","volume":"150","author":"Tomoyose","year":"2010","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"bib43","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.ajo.2008.03.015","article-title":"Los Angeles Latino Eye Study Group. Associations with intraocular pressure in Latinos: the Los Angeles Latino Eye Study","volume":"146","author":"Memarzadeh","year":"2008","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"bib44","doi-asserted-by":"publisher","first-page":"e019416","DOI":"10.1136\/bmjopen-2017-019416","article-title":"Longitudinal changes in intraocular pressure and association with systemic factors and refractive error: Lingtou Eye Cohort Study","volume":"8","author":"Han","year":"2018","journal-title":"BMJ Open"},{"issue":"7","key":"bib45","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1136\/bjophthalmol-2020-316499","article-title":"Intraocular pressure and circumpapillary retinal nerve fibre layer thickness in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA): distributions and associations","volume":"105","author":"McCann","year":"2021","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"bib46","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1136\/bjo.2004.043950","article-title":"Changes in axial length following trabeculectomy and glaucoma drainage device surgery","volume":"89","author":"Francis","year":"2005","journal-title":"Br J Ophthalmol"},{"issue":"7","key":"bib47","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1136\/bjophthalmol-2013-304433","article-title":"Change in choroidal thickness and axial length with change in intraocular pressure after trabeculectomy","volume":"98","author":"Saeedi","year":"2014","journal-title":"Br J Ophthalmol"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.ajo.2020.11.023","article-title":"Prognostic factors for axial length elongation and posterior staphyloma in adults with high myopia: a Japanese observational study","volume":"225","author":"Igarashi-Yokoi","year":"2021","journal-title":"Am J Ophthalmol"},{"issue":"7","key":"bib49","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1136\/bjophthalmol-2012-302442","article-title":"Longitudinal changes in anterior chamber depth and axial length in Asian subjects after trabeculectomy surgery","volume":"97","author":"Husain","year":"2013","journal-title":"Br J Ophthalmol"},{"issue":"12","key":"bib50","doi-asserted-by":"publisher","first-page":"6162","DOI":"10.1167\/iovs.10-5387","article-title":"Effect of induced myopia on scleral myofibroblasts and in vivo ocular biomechanical compliance in the guinea pig","volume":"51","author":"Backhouse","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1097\/OPX.0000000000000588","article-title":"Evaluation of ocular elasticity in high myopia","volume":"92","author":"Pekel","year":"2015","journal-title":"Optom Vis Sci"},{"issue":"5","key":"bib52","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1159\/000267179","article-title":"Axial length and scleral thickness effect on susceptibility to glaucomatous damage: a theoretical model implementing Laplace's law","volume":"24","author":"Cahane","year":"1992","journal-title":"Ophthalmic Res"},{"issue":"1","key":"bib53","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1167\/iovs.15-18053","article-title":"Use and misuse of Laplace's law in ophthalmology","volume":"57","author":"Chung","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib54","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1111\/cxo.12101","article-title":"An examination of the baropathic nature of axial myopia","volume":"97","author":"McMonnies","year":"2014","journal-title":"Clin Exp Optom"},{"issue":"2","key":"bib55","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1076\/ceyr.26.2.65.14513","article-title":"The expandability of the eye in childhood myopia","volume":"26","author":"Schmid","year":"2003","journal-title":"Curr Eye Res"},{"issue":"2","key":"bib56","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1111\/cxo.12302","article-title":"An examination of the relation between intraocular pressure, fundal stretching and myopic pathology","volume":"99","author":"McMonnies","year":"2016","journal-title":"Clin Exp Optom"},{"issue":"2","key":"bib57","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.exer.2006.10.004","article-title":"Effects of cyclic mechanical stretch on extracellular matrix synthesis by human scleral fibroblasts","volume":"84","author":"Shelton","year":"2007","journal-title":"Exp Eye Res"},{"issue":"9","key":"bib58","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1016\/j.ajpath.2020.06.002","article-title":"Up-regulation of matrix metalloproteinase-2 by scleral monocyte\u2013derived macrophages contributes to myopia development","volume":"190","author":"Zhao","year":"2020","journal-title":"Am J Pathol"},{"issue":"2","key":"bib59","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1159\/000055651","article-title":"TIMP-1 production by human scleral fibroblast decreases in response to cyclic mechanical stretching","volume":"33","author":"Yamaoka","year":"2001","journal-title":"Ophthalmic Res"},{"issue":"8","key":"bib60","doi-asserted-by":"publisher","first-page":"3619","DOI":"10.1167\/iovs.17-23580","article-title":"The role of the RhoA\/ROCK signaling pathway in mechanical strain-induced scleral myofibroblast differentiation","volume":"59","author":"Yuan","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"110095","DOI":"10.1016\/j.biopha.2020.110095","article-title":"Mechanical strain affects collagen metabolism-related gene expression in scleral fibroblasts","volume":"126","author":"Xie","year":"2020","journal-title":"Biomed Pharmacother"},{"issue":"8","key":"bib62","doi-asserted-by":"publisher","first-page":"3074","DOI":"10.1167\/iovs.18-26397","article-title":"Changes in choroidal thickness and choroidal blood perfusion in guinea pig myopia","volume":"60","author":"Zhang","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6","key":"bib63","doi-asserted-by":"publisher","first-page":"4045","DOI":"10.1167\/iovs.15-16521","article-title":"Peripapillary choroidal thickness in adult Chinese: the Beijing Eye Study","volume":"56","author":"Jiang","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib64","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.survophthal.2020.06.008","article-title":"Choroidal thickness and ocular growth in childhood","volume":"66","author":"Prousali","year":"2021","journal-title":"Surv Ophthalmol"},{"issue":"2","key":"bib65","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.ajo.2012.07.015","article-title":"The relationship between axial length and choroidal thickness in eyes with high myopia","volume":"155","author":"Flores-Moreno","year":"2013","journal-title":"Am J Ophthalmol"},{"key":"bib66","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1097\/IAE.0000000000002090","article-title":"Longitudinal changes in choroidal and retinal thicknesses in children with myopic shift","volume":"39","author":"Jin","year":"2019","journal-title":"Retina (Philadelphia, Pa.)"},{"issue":"1","key":"bib67","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40662-020-00224-0","article-title":"Choroidal blood perfusion as a potential \u201crapid predictive index\u201d for myopia development and progression","volume":"8","author":"Zhou","year":"2021","journal-title":"Eye Vis (Lond)"},{"issue":"7","key":"bib68","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1111\/aos.v99.7","article-title":"The influence of the choroid on the onset and development of myopia: From perspectives of choroidal thickness and blood flow","volume":"99","author":"Liu","year":"2021","journal-title":"Acta Ophthalmol"},{"issue":"4","key":"bib69","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1080\/15569527.2017.1315128","article-title":"Evaluation of the effects on choroidal thickness of bimatoprost 0.03% versus a brinzolamide 1.0%\/timolol maleate 0.5% fixed combination","volume":"36","author":"Akyol","year":"2017","journal-title":"Cutan Ocul Toxicol"},{"issue":"3","key":"bib70","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1167\/iovs.15-18291","article-title":"Effects of dorzolamide on retinal and choroidal blood flow in the DBA\/2J mouse model of glaucoma","volume":"57","author":"Chandra","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib71","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s10384-016-0482-9","article-title":"Longitudinal change in choroidal thickness after trabeculectomy in primary open-angle glaucoma patients","volume":"61","author":"Yoshikawa","year":"2017","journal-title":"Jpn J Ophthalmol"},{"issue":"9","key":"bib72","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1097\/OPX.0000000000000894","article-title":"Effects of orthokeratology on choroidal thickness and axial length","volume":"93","author":"Chen","year":"2016","journal-title":"Optom Vis Sci"},{"key":"bib73","doi-asserted-by":"publisher","first-page":"4782536","DOI":"10.1155\/2019\/4782536","article-title":"Short-term effect of low-dose atropine and hyperopic defocus on choroidal thickness and axial length in young myopic adults","volume":"2019","author":"Sander","year":"2019","journal-title":"J Ophthalmol"},{"issue":"13","key":"bib74","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1167\/iovs.61.13.25","article-title":"Increased choroidal blood perfusion can inhibit form deprivation myopia in guinea pigs","volume":"61","author":"Zhou","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Investigative Opthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2778086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:24Z","timestamp":1791927084000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2778086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,17]]},"references-count":74,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2021,11,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.62.14.17","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11,17]]}}}