{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:00:41Z","timestamp":1791928841611,"version":"4.3.4"},"reference-count":70,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"3","license":[{"start":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T00:00:00Z","timestamp":1679356800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2023,3,21]]},"DOI":"10.1167\/iovs.64.3.30","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T10:31:27Z","timestamp":1679394687000},"page":"30","source":"Crossref","is-referenced-by-count":8,"title":["Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mouse Corneal Epithelial Cells"],"prefix":"10.1167","volume":"64","author":[{"given":"Zhao-Jing","family":"Lu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"},{"name":"Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China"},{"name":"Research Unit of Ocular Development and Regeneration, Chinese Academy of Medical Sciences, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Guo","family":"Ye","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Liang","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Ke","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi-Kai","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Jing","family":"Huang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cai-Neng","family":"Pan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Heng","family":"Lin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo-Xing","family":"Shi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Feng","family":"Zheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China"},{"name":"Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China"},{"name":"Research Unit of Ocular Development and Regeneration, Chinese Academy of Medical Sciences, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.jtos.2015.11.007","article-title":"Fate mapping mammalian corneal epithelia","volume":"14","author":"Richardson","year":"2016","journal-title":"Ocul Surf"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/0092-8674(89)90958-6","article-title":"Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells","volume":"57","author":"Cotsarelis","year":"1989","journal-title":"Cell"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.preteyeres.2015.04.002","article-title":"Moving epithelia: tracking the fate of mammalian limbal epithelial stem cells","volume":"48","author":"Di Girolamo","year":"2015","journal-title":"Prog Retin Eye Res"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/s10616-007-9063-6","article-title":"Limbal stem cells, a review of their identification and culture for clinical use","volume":"53","author":"O'Sullivan","year":"2007","journal-title":"Cytotechnology"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"19600","DOI":"10.1074\/jbc.M600777200","article-title":"Transcriptional profiling of enriched populations of stem cells versus transient amplifying cells. A comparison of limbal and corneal epithelial basal cells","volume":"281","author":"Zhou","year":"2006","journal-title":"J Biol Chem"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"26633","DOI":"10.1073\/pnas.1912260116","article-title":"Peripheral (not central) corneal epithelia contribute to the closure of an annular debridement injury","volume":"116","author":"Park","year":"2019","journal-title":"Proc Natl Acad Sci USA"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1001\/archopht.119.11.1629","article-title":"Microarray analysis of gene expression in human donor corneas","volume":"119","author":"Jun","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1167\/iovs.10-5242","article-title":"Differentially expressed genes associated with human limbal epithelial phenotypes: new molecules that potentially facilitate selection of stem cell-enriched populations","volume":"52","author":"Takacs","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.exer.2016.11.005","article-title":"PAX6 regulates human corneal epithelium cell identity","volume":"154","author":"Kitazawa","year":"2017","journal-title":"Exp Eye Res"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"3570","DOI":"10.1167\/iovs.19-27656","article-title":"Single-Cell RNA transcriptome helps define the limbal\/corneal epithelial stem\/early transit amplifying cells and how autophagy affects this population","volume":"60","author":"Kaplan","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1167\/iovs.62.9.36","article-title":"Single-cell transcriptomics identifies a unique entity and signature markers of transit-amplifying cells in human corneal limbus","volume":"62","author":"Li","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.jtos.2021.03.010","article-title":"A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells","volume":"21","author":"Collin","year":"2021","journal-title":"Ocul Surf"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.jtos.2021.04.010","article-title":"Molecular identity of human limbal heterogeneity involved in corneal homeostasis and privilege","volume":"21","author":"Dou","year":"2021","journal-title":"Ocul Surf"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.jtos.2020.12.004","article-title":"Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea","volume":"20","author":"Li","year":"2021","journal-title":"Ocul Surf"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"16323","DOI":"10.1038\/s41598-021-94933-8","article-title":"Molecular characteristics and spatial distribution of adult human corneal cell subtypes","volume":"11","author":"Ligocki","year":"2021","journal-title":"Sci Rep"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1038\/s42003-022-03430-9","article-title":"Chromatin accessibility analysis reveals regulatory dynamics and therapeutic relevance of Vogt-Koyanagi-Harada disease","volume":"5","author":"Shi","year":"2022","journal-title":"Commun Biol"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1016\/j.cell.2019.05.031","article-title":"Comprehensive integration of single-cell data","volume":"177","author":"Stuart","year":"2019","journal-title":"Cell"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat Methods"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"e133","DOI":"10.1093\/nar\/gkz601","article-title":"Single-cell signature explorer for comprehensive visualization of single cell signatures across scRNA-seq datasets","volume":"47","author":"Pont","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1038\/nrm3591","article-title":"Molecular regulation of stem cell quiescence","volume":"14","author":"Cheung","year":"2013","journal-title":"Nat Rev Mol Cell Biol"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1038\/s41588-021-00790-6","article-title":"ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis","volume":"53","author":"Granja","year":"2021","journal-title":"Nat Genet"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1016\/j.cell.2018.05.061","article-title":"Recovering gene interactions from single-cell data using data diffusion","volume":"174","author":"van Dijk","year":"2018","journal-title":"Cell"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.stem.2020.11.015","article-title":"Integrative single-cell RNA-Seq and ATAC-Seq analysis of human developmental hematopoiesis","volume":"28","author":"Ranzoni","year":"2021","journal-title":"Cell Stem Cell"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","article-title":"Metascape provides a biologist-oriented resource for the analysis of systems-level datasets","volume":"10","author":"Zhou","year":"2019","journal-title":"Nat Commun"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"13953","DOI":"10.1074\/jbc.RA119.008618","article-title":"Deletion of the transmembrane protein Prom1b in zebrafish disrupts outer-segment morphogenesis and causes photoreceptor degeneration","volume":"294","author":"Lu","year":"2019","journal-title":"J Biol Chem"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1186\/s12974-020-01812-6","article-title":"The neuroregenerative effects of topical decorin on the injured mouse cornea","volume":"17","author":"Wu","year":"2020","journal-title":"J Neuroinflammation"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1097\/ICO.0000000000000457","article-title":"Immunocytochemical diagnosis of limbal stem cell deficiency: comparative analysis of current corneal and conjunctival biomarkers","volume":"34","author":"Poli","year":"2015","journal-title":"Cornea"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.exer.2017.03.006","article-title":"The analysis of human conjunctival epithelium proteome in ocular surface diseases using impression cytology and 2D-DIGE","volume":"167","author":"Soria","year":"2018","journal-title":"Exp Eye Res"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1016\/j.stem.2021.04.003","article-title":"Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing","volume":"28","author":"Altshuler","year":"2021","journal-title":"Cell Stem Cell"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1136\/bjo.2003.037853","article-title":"Analysis of p63 and cytokeratin expression in a cultivated limbal autograft used in the treatment of limbal stem cell deficiency","volume":"88","author":"Harkin","year":"2004","journal-title":"Br J Ophthalmol"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1016\/j.stemcr.2022.04.008","article-title":"Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids","volume":"17","author":"Ramovs","year":"2022","journal-title":"Stem Cell Reports"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1634\/stemcells.2005-0382","article-title":"Integrins in slow-cycling corneal epithelial cells at the limbus in the mouse","volume":"24","author":"Pajoohesh-Ganji","year":"2006","journal-title":"Stem Cells"},{"key":"bib33","first-page":"1442","article-title":"The X, Y, Z hypothesis of corneal epithelial maintenance","volume":"24","author":"Thoft","year":"1983","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1002\/stem.1840","article-title":"Lineage tracing of stem and progenitor cells of the murine corneal epithelium","volume":"33","author":"Amitai-Lange","year":"2015","journal-title":"Stem Cells"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.3390\/cells11131983","article-title":"Differentiation trajectory of limbal stem and progenitor cells under normal homeostasis and upon corneal wounding","volume":"11","author":"Song","year":"2022","journal-title":"Cells"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"108138","DOI":"10.1016\/j.exer.2020.108138","article-title":"Integrin: Basement membrane adhesion by corneal epithelial and endothelial cells","volume":"198","author":"McKay","year":"2020","journal-title":"Exp Eye Res"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"4734","DOI":"10.1167\/iovs.10-6486","article-title":"Wnt\/beta-catenin signaling regulates proliferation of human cornea epithelial stem\/progenitor cells","volume":"52","author":"Nakatsu","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.gep.2012.12.001","article-title":"The expression of NOTCH2, HES1 and SOX9 during mouse retinal development","volume":"13","author":"Zhu","year":"2013","journal-title":"Gene Expr Patterns"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"e03564","DOI":"10.7554\/eLife.03564","article-title":"Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma","volume":"3","author":"Wan","year":"2014","journal-title":"Elife"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"e0238578","DOI":"10.1371\/journal.pone.0238578","article-title":"Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells","volume":"15","author":"Wu","year":"2020","journal-title":"PLoS One"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"E3919","DOI":"10.1073\/pnas.1304311110","article-title":"Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus","volume":"110","author":"Robertshaw","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/j.neuron.2013.06.040","article-title":"Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues","volume":"79","author":"Gil-Sanz","year":"2013","journal-title":"Neuron"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.neuron.2006.12.012","article-title":"An RNAi-based approach identifies molecules required for glutamatergic and GABAergic synapse development","volume":"53","author":"Paradis","year":"2007","journal-title":"Neuron"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1038\/s41576-019-0128-0","article-title":"Long-range enhancer-promoter contacts in gene expression control","volume":"20","author":"Schoenfelder","year":"2019","journal-title":"Nat Rev Genet"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/978-1-60761-854-6","article-title":"Regulatory regions in DNA: promoters, enhancers, silencers, and insulators","volume":"674","author":"Riethoven","year":"2010","journal-title":"Methods Mol Biol"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1186\/gb-2012-13-1-238","article-title":"Transcriptional enhancers in development and disease","volume":"13","author":"Sakabe","year":"2012","journal-title":"Genome Biol"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s12311-019-01089-3","article-title":"Common regulatory targets of NFIA, NFIX and NFIB during postnatal cerebellar development","volume":"19","author":"Fraser","year":"2020","journal-title":"Cerebellum"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"34304","DOI":"10.1074\/jbc.M113.504399","article-title":"The Ets transcription factor EHF as a regulator of cornea epithelial cell identity","volume":"288","author":"Stephens","year":"2013","journal-title":"J Biol Chem"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.exer.2016.11.009","article-title":"Endogenous retinoic acid signaling is required for maintenance and regeneration of cornea","volume":"154","author":"Kumar","year":"2017","journal-title":"Exp Eye Res"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"18937","DOI":"10.1074\/jbc.M117.793117","article-title":"Characterization of enhancers and the role of the transcription factor KLF7 in regulating corneal epithelial differentiation","volume":"292","author":"Klein","year":"2017","journal-title":"J Biol Chem"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1111\/ceo.2006.34.issue-1","article-title":"Limbal stem cells: the search for a marker","volume":"34","author":"Chee","year":"2006","journal-title":"Clin Exp Ophthalmol"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"e67315","DOI":"10.7554\/eLife.67315","article-title":"Canonical NF-kappaB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid","volume":"10","author":"Yu","year":"2021","journal-title":"Elife"},{"key":"bib53","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1038\/nature07406","article-title":"Oligopotent stem cells are distributed throughout the mammalian ocular surface","volume":"456","author":"Majo","year":"2008","journal-title":"Nature"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"5169","DOI":"10.1038\/s41598-017-04569-w","article-title":"Identification for differential localization of putative corneal epithelial stem cells in mouse and human","volume":"7","author":"Li","year":"2017","journal-title":"Sci Rep"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.celrep.2017.12.040","article-title":"Corneal-committed cells restore the stem cell pool and tissue boundary following injury","volume":"22","author":"Nasser","year":"2018","journal-title":"Cell Rep"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1038\/nm1328","article-title":"Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis","volume":"11","author":"Ito","year":"2005","journal-title":"Nat Med"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1038\/nature12777","article-title":"Dedifferentiation of committed epithelial cells into stem cells in vivo","volume":"503","author":"Tata","year":"2013","journal-title":"Nature"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.cell.2013.09.008","article-title":"Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium","volume":"155","author":"Stange","year":"2013","journal-title":"Cell"},{"key":"bib59","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1080\/21623945.2022.2063015","article-title":"A chromatin accessibility landscape during early adipogenesis of human adipose-derived stem cells","volume":"11","author":"Li","year":"2022","journal-title":"Adipocyte"},{"key":"bib60","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1186\/s13059-022-02762-3","article-title":"Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis","volume":"23","author":"Clark","year":"2022","journal-title":"Genome Biol"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1002\/glia.23102","article-title":"Corneal epithelial cells function as surrogate Schwann cells for their sensory nerves","volume":"65","author":"Stepp","year":"2017","journal-title":"Glia"},{"key":"bib62","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1186\/s13073-022-01081-3","article-title":"Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis","volume":"14","author":"Armaka","year":"2022","journal-title":"Genome Med"},{"key":"bib63","doi-asserted-by":"publisher","first-page":"4069","DOI":"10.1038\/s41467-022-31770-x","article-title":"A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys","volume":"13","author":"Qu","year":"2022","journal-title":"Nat Commun"},{"key":"bib64","doi-asserted-by":"publisher","first-page":"806","DOI":"10.3390\/cells11050806","article-title":"Deciphering the retinal epigenome during development, disease and reprogramming: advancements, challenges and perspectives","volume":"11","author":"Zibetti","year":"2022","journal-title":"Cells"},{"key":"bib65","doi-asserted-by":"publisher","first-page":"109994","DOI":"10.1016\/j.celrep.2021.109994","article-title":"Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina","volume":"37","author":"Lyu","year":"2021","journal-title":"Cell Rep"},{"key":"bib66","doi-asserted-by":"publisher","first-page":"e510","DOI":"10.1038\/cddis.2013.14","article-title":"Nuclear factor-kappaB modulates osteogenesis of periodontal ligament stem cells through competition with beta-catenin signaling in inflammatory microenvironments","volume":"4","author":"Chen","year":"2013","journal-title":"Cell Death Dis"},{"key":"bib67","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1089\/ars.2009.2755","article-title":"Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-kappaB signaling","volume":"12","author":"Afzal","year":"2010","journal-title":"Antioxid Redox Signal"},{"key":"bib68","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1006\/dbio.2000.9789","article-title":"Convergence of dorsal, DPP, and EGFR signaling pathways subdivides the drosophila neuroectoderm into three dorsal-ventral columns","volume":"224","author":"von Ohlen","year":"2000","journal-title":"Dev Biol"},{"key":"bib69","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1016\/j.cell.2014.10.031","article-title":"Proinflammatory signaling regulates hematopoietic stem cell emergence","volume":"159","author":"Espin-Palazon","year":"2014","journal-title":"Cell"},{"key":"bib70","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.exer.2016.08.020","article-title":"Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye","volume":"152","author":"Kadmiel","year":"2016","journal-title":"Exp Eye Res"}],"container-title":["Investigative Opthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2785462","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:42Z","timestamp":1791927102000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2785462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,21]]},"references-count":70,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.64.3.30","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,21]]}}}