{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:00:21Z","timestamp":1791928821916,"version":"4.3.4"},"reference-count":111,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"2","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2024,2,6]]},"DOI":"10.1167\/iovs.65.2.12","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T13:08:11Z","timestamp":1707224891000},"page":"12","source":"Crossref","is-referenced-by-count":3,"title":["Phylogenetic and Recombination Analysis of Clinical Vitreous Humor\u2013Derived Adenovirus Isolates Reveals Discordance Between Serotype and Phylogeny"],"prefix":"10.1167","volume":"65","author":[{"given":"Aaron W.","family":"Kolb","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viet Q.","family":"Chau","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darlene L.","family":"Miller","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas A.","family":"Yannuzzi","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis R.","family":"Brandt","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States"},{"name":"McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States"},{"name":"Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"3","key":"bib1","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1016\/0042-6822(58)90050-3","article-title":"Hemagglutination by adenoviruses","volume":"5","author":"Rosen","year":"1958","journal-title":"Virology"},{"issue":"2","key":"bib2","doi-asserted-by":"publisher","first-page":"260","DOI":"10.3181\/00379727-91-22231","article-title":"Additional serotypes of the APC virus group","volume":"91","author":"Rowe","year":"1956","journal-title":"Proc Soc Exp Biol Med"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/0042-6822(63)90286-1","article-title":"A short description of the adenovirus group","volume":"20","author":"Pereira","year":"1963","journal-title":"Virology"},{"issue":"5","key":"bib4","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1128\/jvi.4.5.663-670.1969","article-title":"Immunological relationships between hexons of certain human adenoviruses","volume":"4","author":"Norrby","year":"1969","journal-title":"J Virol"},{"issue":"5","key":"bib5","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1128\/jvi.4.5.671-680.1969","article-title":"Immunological and other biological characteristics of pentons of human adenoviruses","volume":"4","author":"Wadell","year":"1969","journal-title":"J Virol"},{"issue":"2","key":"bib6","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3181\/00379727-132-34227","article-title":"Hemagglutination with adenovirus serotypes belonging to Rosen's subgroups II and 3","volume":"132","author":"Wadell","year":"1969","journal-title":"Proc Soc Exp Biol Med"},{"issue":"9","key":"bib7","doi-asserted-by":"publisher","first-page":"3963","DOI":"10.1128\/JCM.42.9.3963-3969.2004","article-title":"Comprehensive detection and serotyping of human adenoviruses by PCR and sequencing","volume":"42","author":"Sarantis","year":"2004","journal-title":"J Clin Microbiol"},{"issue":"9","key":"bib8","first-page":"2010","article-title":"Rapid detection and typing of oculopathogenic strain of subgenus D adenoviruses by fiber-based PCR and restriction enzyme analysis","volume":"42","author":"Adhikary","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"bib9","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1111\/mim.2000.44.issue-10","article-title":"Single-tube multiplex PCR for rapid and sensitive diagnosis of subgenus B and other subgenera adenoviruses in clinical samples","volume":"44","author":"Fujimoto","year":"2000","journal-title":"Microbiol Immunol"},{"issue":"1","key":"bib10","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.bj.2021.08.009","article-title":"Human adenovirus infections in pediatric population - an update on clinico-pathologic correlation","volume":"45","author":"Shieh","year":"2022","journal-title":"Biomed J"},{"issue":"12","key":"bib11","doi-asserted-by":"publisher","first-page":"1867","DOI":"10.1016\/j.ophtha.2017.05.033","article-title":"Disinfection of tonometers: a report by the American Academy of Ophthalmology","volume":"124","author":"Junk","year":"2017","journal-title":"Ophthalmology"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/1471-2334-12-55","article-title":"Epidemiology of severe pediatric adenovirus lower respiratory tract infections in Manitoba, Canada, 1991-2005","volume":"12","author":"Alharbi","year":"2012","journal-title":"BMC Infect Dis"},{"issue":"3","key":"bib13","doi-asserted-by":"publisher","first-page":"e0212434","DOI":"10.1371\/journal.pone.0212434","article-title":"Infectious human adenoviruses are shed in urine even after disappearance of urethral symptoms","volume":"14","author":"Hanaoka","year":"2019","journal-title":"PLoS One"},{"issue":"4","key":"bib14","doi-asserted-by":"publisher","first-page":"381e1","DOI":"10.1016\/j.cmi.2015.12.013","article-title":"Persistence and reactivation of human adenoviruses in the gastrointestinal tract","volume":"22","author":"Kosulin","year":"2016","journal-title":"Clin Microbiol Infect"},{"issue":"2","key":"bib15","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1097\/00003226-199503000-00010","article-title":"Adenovirus epithelial keratitis","volume":"14","author":"Chodosh","year":"1995","journal-title":"Cornea"},{"issue":"3","key":"bib16","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1086\/cid.2006.43.issue-3","article-title":"Adenovirus infections in transplant recipients","volume":"43","author":"Ison","year":"2006","journal-title":"Clin Infect Dis"},{"issue":"3","key":"bib17","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1002\/rmv.v13:3","article-title":"The impact of adenovirus infection on the immunocompromised host","volume":"13","author":"Kojaoghlanian","year":"2003","journal-title":"Rev Med Virol"},{"issue":"3","key":"bib18","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1007\/s10875-011-9636-1","article-title":"Survival and predictors of death among primary immunodeficient patients: a registry-based study","volume":"32","author":"Al-Herz","year":"2012","journal-title":"J Clin Immunol"},{"issue":"2","key":"bib19","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1055\/s-2007-976494","article-title":"Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection","volume":"28","author":"Kim","year":"2007","journal-title":"Semin Respir Crit Care Med"},{"issue":"1","key":"bib20","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1128\/JCM.01893-13","article-title":"Disseminated adenovirus infection in cancer patients presenting with focal pulmonary consolidation","volume":"52","author":"Lee","year":"2014","journal-title":"J Clin Microbiol"},{"issue":"9279","key":"bib21","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/S0140-6736(01)05580-5","article-title":"Prediction of severe disseminated adenovirus infection by serum PCR","volume":"358","author":"Echavarria","year":"2001","journal-title":"Lancet"},{"key":"bib22","first-page":"837","article-title":"Keratitis punctata superficialis","volume":"2","author":"Fuchs","year":"1889","journal-title":"Wiener klinischen Wochenschrift"},{"key":"bib23","first-page":"613","article-title":"Ueber eine eigenth\u00fcmlich Form der Hornhautenz\u00fcndung","volume":"2","author":"Stellwag von Carion","year":"1889","journal-title":"Wiener klinische Wochenschrift"},{"issue":"1","key":"bib24","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1084\/jem.77.1.71","article-title":"Epidemic keratoconjunctivitis : I. Isolation and identification of a filterable virus","volume":"77","author":"Sanders","year":"1943","journal-title":"J Exp Med"},{"issue":"3181","key":"bib25","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1126\/science.122.3181.1190.b","article-title":"New type of APC virus from epidemic keratoconjunctivitis","volume":"122","author":"Jawetz","year":"1955","journal-title":"Science"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"100826","DOI":"10.1016\/j.preteyeres.2019.100826","article-title":"Mystery eye: human adenovirus and the enigma of epidemic keratoconjunctivitis","volume":"76","author":"Jonas","year":"2020","journal-title":"Prog Retin Eye Res"},{"issue":"4","key":"bib27","doi-asserted-by":"publisher","first-page":"100166","DOI":"10.1016\/j.xops.2022.100166","article-title":"Machine learning prediction of adenovirus D8 conjunctivitis complications from viral whole-genome sequence","volume":"2","author":"Nakamichi","year":"2022","journal-title":"Ophthalmol Sci"},{"issue":"4","key":"bib28","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/j.jcv.2014.10.015","article-title":"Human adenovirus type 8: the major agent of epidemic keratoconjunctivitis (EKC)","volume":"61","author":"Adhikary","year":"2014","journal-title":"J Clin Virol"},{"issue":"1","key":"bib29","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1002\/jmv.v84.1","article-title":"Surveillance of adenovirus D in patients with epidemic keratoconjunctivitis from Fukui Prefecture, Japan, 1995\u20132010","volume":"84","author":"Nakamura","year":"2012","journal-title":"J Med Virol"},{"issue":"1","key":"bib30","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1136\/bjo.2009.178772","article-title":"Epidemiological and virological features of epidemic keratoconjunctivitis due to new human adenovirus type 54 in Japan","volume":"95","author":"Kaneko","year":"2011","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"bib31","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1097\/00004397-200201000-00008","article-title":"A twenty-one year surveillance of adenoviral conjunctivitis in Sapporo, Japan","volume":"42","author":"Aoki","year":"2002","journal-title":"Int Ophthalmol Clin."},{"issue":"2","key":"bib32","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1136\/bjo.67.2.111","article-title":"Adenovirus serotypes isolated from ocular infections in London","volume":"67","author":"Darougar","year":"1983","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"bib33","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1097\/01.ico.0000170693.13326.fb","article-title":"Adenoviral keratoconjunctivitis in a tertiary care eye clinic","volume":"25","author":"Butt","year":"2006","journal-title":"Cornea"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1007\/s003470070025","article-title":"Lokales Cyclosporin A bei Nummuli nach Keratokonjunktivitis epidemica","volume":"97","author":"Reinhard","year":"2000","journal-title":"Ophthalmologe"},{"issue":"4","key":"bib35","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1111\/aos.2015.93.issue-4","article-title":"Evaluation of the impact of persistent subepithelial corneal infiltrations on the visual performance and corneal optical quality after epidemic keratoconjunctivitis","volume":"93","author":"Kurna","year":"2014","journal-title":"Acta Ophthalmol"},{"issue":"4","key":"bib36","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.ophtha.2022.12.020","article-title":"Adenovirus-associated uveitis with necrotizing retinitis","volume":"130","author":"Sugita","year":"2023","journal-title":"Ophthalmology"},{"issue":"1","key":"bib37","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.molcel.2004.11.041","article-title":"The structure of the human adenovirus 2 penton","volume":"17","author":"Zubieta","year":"2005","journal-title":"Mol Cell"},{"issue":"9","key":"bib38","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1038\/sj.emboj.7600653","article-title":"A quasi-atomic model of human adenovirus type 5 capsid","volume":"24","author":"Fabry","year":"2005","journal-title":"EMBO J"},{"issue":"2","key":"bib39","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.jmb.2005.11.048","article-title":"Structure of the dodecahedral penton particle from human adenovirus type 3","volume":"356","author":"Fuschiotti","year":"2006","journal-title":"J Mol Biol"},{"issue":"1","key":"bib40","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/0092-8674(91)90578-M","article-title":"Image reconstruction reveals the complex molecular organization of adenovirus","volume":"67","author":"Stewart","year":"1991","journal-title":"Cell"},{"issue":"24","key":"bib41","doi-asserted-by":"publisher","first-page":"e00850","DOI":"10.1128\/JVI.00850-17","article-title":"Atomic structures of minor proteins VI and VII in human adenovirus","volume":"91","author":"Dai","year":"2017","journal-title":"J Virol"},{"issue":"24","key":"bib42","doi-asserted-by":"publisher","first-page":"13699","DOI":"10.1073\/pnas.1920896117","article-title":"Dynamic competition for hexon binding between core protein VII and lytic protein VI promotes adenovirus maturation and entry","volume":"117","author":"Hernando-Perez","year":"2020","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"bib43","doi-asserted-by":"publisher","first-page":"e1602670","DOI":"10.1126\/sciadv.1602670","article-title":"Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses","volume":"3","author":"Yu","year":"2017","journal-title":"Sci Adv"},{"issue":"2","key":"bib44","doi-asserted-by":"publisher","first-page":"e1004657","DOI":"10.1371\/journal.ppat.1004657","article-title":"Human adenovirus 52 uses sialic acid-containing glycoproteins and the coxsackie and adenovirus receptor for binding to target cells","volume":"11","author":"Lenman","year":"2015","journal-title":"PLoS Pathog"},{"issue":"8","key":"bib45","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1016\/j.tips.2012.04.005","article-title":"Adenovirus receptors: implications for targeting of viral vectors","volume":"33","author":"Arnberg","year":"2012","journal-title":"Trends Pharmacol Sci"},{"issue":"5304","key":"bib46","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1126\/science.275.5304.1320","article-title":"Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5","volume":"275","author":"Bergelson","year":"1997","journal-title":"Science"},{"issue":"1","key":"bib47","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/nm.2267","article-title":"The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis","volume":"17","author":"Nilsson","year":"2011","journal-title":"Nat Med"},{"issue":"14","key":"bib48","doi-asserted-by":"publisher","first-page":"7727","DOI":"10.1128\/JVI.78.14.7727-7736.2004","article-title":"Crystal structure of species D adenovirus fiber knobs and their sialic acid binding sites","volume":"78","author":"Burmeister","year":"2004","journal-title":"J Virol"},{"issue":"15","key":"bib49","doi-asserted-by":"publisher","first-page":"7210","DOI":"10.1128\/JVI.75.15.7210-7214.2001","article-title":"Adenovirus type 9 fiber knob binds to the coxsackie B virus-adenovirus receptor (CAR) with lower affinity than fiber knobs of other CAR-binding adenovirus serotypes","volume":"75","author":"Kirby","year":"2001","journal-title":"J Virol"},{"issue":"11","key":"bib50","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1038\/nm952","article-title":"CD46 is a cellular receptor for group B adenoviruses","volume":"9","author":"Gaggar","year":"2003","journal-title":"Nat Med"},{"issue":"1","key":"bib51","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1038\/nm.2270","article-title":"Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14","volume":"17","author":"Wang","year":"2011","journal-title":"Nat Med"},{"issue":"16","key":"bib52","doi-asserted-by":"publisher","first-page":"7923","DOI":"10.1128\/JVI.00754-08","article-title":"Structural variations in species B adenovirus fibers impact CD46 association","volume":"82","author":"Pache","year":"2008","journal-title":"J Virol"},{"issue":"2","key":"bib53","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.virol.2008.02.013","article-title":"Conservation of fiber structure and CD46 usage by subgroup B2 adenoviruses","volume":"375","author":"Pache","year":"2008","journal-title":"Virology"},{"issue":"1-2","key":"bib54","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.virusres.2006.07.009","article-title":"Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors","volume":"122","author":"Short","year":"2006","journal-title":"Virus Res"},{"issue":"13","key":"bib55","doi-asserted-by":"publisher","first-page":"6390","DOI":"10.1128\/JVI.00514-11","article-title":"Multimerization of adenovirus serotype 3 fiber knob domains is required for efficient binding of virus to desmoglein 2 and subsequent opening of epithelial junctions","volume":"85","author":"Wang","year":"2011","journal-title":"J Virol"},{"issue":"11","key":"bib56","doi-asserted-by":"publisher","first-page":"5405","DOI":"10.1128\/JVI.75.11.5405-5409.2001","article-title":"Integrin av\u00df1 is an adenovirus coreceptor","volume":"75","author":"Li","year":"2001","journal-title":"J Virol"},{"issue":"1","key":"bib57","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1083\/jcb.127.1.257","article-title":"Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization","volume":"127","author":"Wickham","year":"1994","journal-title":"J Cell Biol"},{"issue":"5","key":"bib58","doi-asserted-by":"publisher","first-page":"e02019","DOI":"10.1128\/JVI.02019-16","article-title":"Human adenovirus type 37 uses aV\u00df1 and a3\u00df1 integrins for infection of human corneal cells","volume":"91","author":"Storm","year":"2017","journal-title":"J Virol"},{"issue":"1","key":"bib59","doi-asserted-by":"publisher","first-page":"e01474","DOI":"10.1128\/JVI.01474-18","article-title":"av\u00df3 integrin is required for efficient infection of epithelial cells with human adenovirus type 26","volume":"93","author":"Nestic","year":"2019","journal-title":"J Virol"},{"issue":"10","key":"bib60","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1167\/iovs.64.10.16","article-title":"Phylogenetic and genomic characterization of whole genome sequences of ocular herpes simplex virus type 1 isolates identifies possible virulence determinants in humans","volume":"64","author":"Chau","year":"2023","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib61","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1038\/s41592-020-01056-5","article-title":"Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm","volume":"18","author":"Cheng","year":"2021","journal-title":"Nat Methods"},{"issue":"7","key":"bib62","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol Biol Evol"},{"issue":"4","key":"bib63","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1093\/molbev\/mst010","article-title":"MAFFT multiple sequence alignment software version 7: improvements in performance and usability","volume":"30","author":"Katoh","year":"2013","journal-title":"Mol Biol Evol"},{"issue":"5","key":"bib64","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.1093\/molbev\/msaa015","article-title":"IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era","volume":"37","author":"Minh","year":"2020","journal-title":"Mol Biol Evol"},{"issue":"2","key":"bib65","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1093\/molbev\/msj030","article-title":"Application of phylogenetic networks in evolutionary studies","volume":"23","author":"Huson","year":"2006","journal-title":"Mol Biol Evol"},{"issue":"1","key":"bib66","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1186\/s12864-020-06847-w","article-title":"Genomic nucleotide-based distance analysis for delimiting old world monkey derived herpes simplex virus species","volume":"21","author":"Kolb","year":"2020","journal-title":"BMC Genomics"},{"issue":"1","key":"bib67","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1186\/s12864-017-4283-4","article-title":"Phylogenetic and recombination analysis of the herpesvirus genus varicellovirus","volume":"18","author":"Kolb","year":"2017","journal-title":"BMC Genomics"},{"issue":"3","key":"bib68","first-page":"275","article-title":"The rapid generation of mutation data matrices from protein sequences","volume":"8","author":"Jones","year":"1992","journal-title":"Comput Appl Biosci"},{"key":"bib71","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/978-1-4939-6622-6","article-title":"Detecting and analyzing genetic recombination using RDP4","volume":"1525","author":"Martin","year":"2017","journal-title":"Methods Mol Biol"},{"issue":"1","key":"bib72","first-page":"82","article-title":"Limitations of the evolutionary parsimony method of phylogenetic analysis","volume":"7","author":"Jin","year":"1990","journal-title":"Mol Biol Evol"},{"issue":"8","key":"bib73","doi-asserted-by":"publisher","first-page":"2144","DOI":"10.1093\/bioinformatics\/btac075","article-title":"RF-Net 2: fast inference of virus reassortment and hybridization networks","volume":"38","author":"Markin","year":"2022","journal-title":"Bioinformatics"},{"issue":"15","key":"bib74","doi-asserted-by":"publisher","first-page":"2392","DOI":"10.1093\/bioinformatics\/btx155","article-title":"IcyTree: rapid browser-based visualization for phylogenetic trees and networks","volume":"33","author":"Vaughan","year":"2017","journal-title":"Bioinformatics"},{"issue":"1","key":"bib75","first-page":"10","article-title":"Genomic analysis of a large set of currently-and historically-important human adenovirus pathogens","volume":"7","author":"Ismail","year":"2018","journal-title":"Emerg Microbes Infect"},{"issue":"26","key":"bib76","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1136\/vr.162.26.867","article-title":"PCV-2 genotype definition and nomenclature","volume":"162","author":"Segales","year":"2008","journal-title":"Vet Rec"},{"issue":"pt 7","key":"bib77","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1099\/vir.0.000100","article-title":"Global molecular genetic analysis of porcine circovirus type 2 (PCV2) sequences confirms the presence of four main PCV2 genotypes and reveals a rapid increase of PCV2d","volume":"96","author":"Xiao","year":"2015","journal-title":"J Gen Virol"},{"issue":"11","key":"bib79","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1089\/aid.1995.11.1423","article-title":"Identification of breakpoints in intergenotypic recombinants of HIV type 1 by bootscanning","volume":"11","author":"Salminen","year":"1995","journal-title":"AIDS Res Hum Retroviruses"},{"issue":"1","key":"bib80","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1089\/aid.2005.21.98","article-title":"A modified bootscan algorithm for automated identification of recombinant sequences and recombination breakpoints","volume":"21","author":"Martin","year":"2005","journal-title":"AIDS Res Hum Retroviruses"},{"issue":"5","key":"bib81","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1080\/09273948.2019.1624780","article-title":"Human adenovirus: an unusual causative agent for acute retinal necrosis presented with central retinal vascular occlusion","volume":"28","author":"Ozdemir","year":"2020","journal-title":"Ocul Immunol Inflamm"},{"issue":"2","key":"bib82","doi-asserted-by":"publisher","first-page":"293","DOI":"10.3390\/v13020293","article-title":"Adenovirus and the cornea: more than meets the eye","volume":"13","author":"Rajaiya","year":"2021","journal-title":"Viruses"},{"key":"bib83","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.virol.2015.08.018","article-title":"Recombination of the epsilon determinant and corneal tropism: human adenovirus species D types 15, 29, 56, and 69","volume":"485","author":"Singh","year":"2015","journal-title":"Virology"},{"key":"bib84","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1186\/1471-2164-9-213","article-title":"Genomic and bioinformatics analysis of human adenovirus type 37: new insights into corneal tropism","volume":"9","author":"Robinson","year":"2008","journal-title":"BMC Genomics"},{"issue":"4","key":"bib85","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1167\/iovs.09-4367","article-title":"Adenovirus vectors targeting distinct cell types in the retina","volume":"51","author":"Sweigard","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"bib86","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1038\/sj.mt.6300203","article-title":"Improved retinal transduction in vivo and photoreceptor-specific transgene expression using adenovirus vectors with modified penton base","volume":"15","author":"Cashman","year":"2007","journal-title":"Mol Ther"},{"issue":"6","key":"bib87","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1167\/iovs.03-0730","article-title":"Efficient gene transfer into retinal cells using adenoviral vectors: dependence on receptor expression","volume":"45","author":"Mallam","year":"2004","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"24","key":"bib88","doi-asserted-by":"publisher","first-page":"3583","DOI":"10.1002\/feb2.v593.24","article-title":"Genomic foundations of evolution and ocular pathogenesis in human adenovirus species D","volume":"593","author":"Ismail","year":"2019","journal-title":"FEBS Lett"},{"issue":"2","key":"bib89","doi-asserted-by":"publisher","first-page":"465","DOI":"10.3181\/00379727-97-23776","article-title":"Serotype composition of the adenovirus group","volume":"97","author":"Rowe","year":"1958","journal-title":"Proc Soc Exp Biol Med"},{"issue":"24","key":"bib90","doi-asserted-by":"publisher","first-page":"15265","DOI":"10.1128\/JVI.79.24.15265-15276.2005","article-title":"Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy","volume":"79","author":"Madisch","year":"2005","journal-title":"J Virol"},{"key":"bib91","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1038\/srep01812","article-title":"Molecular evolution of human adenoviruses","volume":"3","author":"Robinson","year":"2013","journal-title":"Sci Rep"},{"issue":"20","key":"bib92","doi-asserted-by":"publisher","first-page":"12635","DOI":"10.1128\/JVI.79.20.12635-12642.2005","article-title":"Comparative sequence analysis of the hexon gene in the entire spectrum of human adenovirus serotypes: phylogenetic, taxonomic, and clinical implications","volume":"79","author":"Ebner","year":"2005","journal-title":"J Virol"},{"issue":"3","key":"bib93","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1007\/s12250-020-00334-y","article-title":"Genetic analysis of human adenovirus type 7 strains circulating in different parts of China","volume":"36","author":"Duan","year":"2021","journal-title":"Virol Sin"},{"issue":"10","key":"bib94","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0076267","article-title":"Using HSV-1 genome phylogenetics to track past human migrations","volume":"8","author":"Kolb","year":"2013","journal-title":"PLoS One"},{"issue":"6","key":"bib95","doi-asserted-by":"publisher","first-page":"e5635","DOI":"10.1371\/journal.pone.0005635","article-title":"Evidence of molecular evolution driven by recombination events influencing tropism in a novel human adenovirus that causes epidemic keratoconjunctivitis","volume":"4","author":"Walsh","year":"2009","journal-title":"PLoS One"},{"issue":"1","key":"bib96","doi-asserted-by":"publisher","first-page":"9781","DOI":"10.1038\/s41598-019-46228-2","article-title":"Human adenovirus species C recombinant virus continuously circulated in China","volume":"9","author":"Yang","year":"2019","journal-title":"Sci Rep"},{"issue":"3","key":"bib97","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1128\/jvi.51.3.571-577.1984","article-title":"Replication and recombination in adenovirus-infected cells are temporally and functionally related","volume":"51","author":"Young","year":"1984","journal-title":"J Virol"},{"issue":"1","key":"bib98","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s12985-020-01387-x","article-title":"Whole genomic analysis of a potential recombinant human adenovirus type 1 in Qinghai plateau, China","volume":"17","author":"Yu","year":"2020","journal-title":"Virol J"},{"issue":"6","key":"bib99","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1128\/JCM.06523-11","article-title":"Two adenovirus serotype 3 outbreaks associated with febrile respiratory disease and pharyngoconjunctival fever in children under 15 years of age in Hangzhou, China, during 2011","volume":"50","author":"Xie","year":"2012","journal-title":"J Clin Microbiol"},{"issue":"6","key":"bib100","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1097\/00007611-198706000-00012","article-title":"Community outbreak of adenovirus type 7a infections associated with a swimming pool","volume":"80","author":"Turner","year":"1987","journal-title":"South Med J"},{"issue":"1","key":"bib101","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12985-018-0983-x","article-title":"A triplex quantitative real-time PCR assay for differential detection of human adenovirus serotypes 2, 3 and 7","volume":"15","author":"Qiu","year":"2018","journal-title":"Virol J"},{"issue":"11","key":"bib102","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1038\/s41564-020-0770-5","article-title":"A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology","volume":"5","author":"Rambaut","year":"2020","journal-title":"Nat Microbiol"},{"issue":"1","key":"bib103","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1093\/bioinformatics\/14.1.68","article-title":"SplitsTree: analyzing and visualizing evolutionary data","volume":"14","author":"Huson","year":"1998","journal-title":"Bioinformatics"},{"key":"bib104","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.meegid.2018.02.026","article-title":"Recombination in the rabies virus and other lyssaviruses","volume":"60","author":"Deviatkin","year":"2018","journal-title":"Infect Genet Evol"},{"issue":"24","key":"bib105","doi-asserted-by":"publisher","first-page":"13049","DOI":"10.1128\/JVI.05779-11","article-title":"Genomic analysis of the vaccinia virus strain variants found in Dryvax vaccine","volume":"85","author":"Qin","year":"2011","journal-title":"J Virol"},{"issue":"1","key":"bib106","doi-asserted-by":"publisher","first-page":"vez059","DOI":"10.1093\/ve\/vez059","article-title":"Intragenic recombination influences rotavirus diversity and evolution","volume":"6","author":"Hoxie","year":"2020","journal-title":"Virus Evol"},{"issue":"3","key":"bib107","doi-asserted-by":"publisher","first-page":"e1005896","DOI":"10.1371\/journal.pgen.1005896","article-title":"Inferring phylogenetic networks with maximum pseudolikelihood under incomplete lineage sorting","volume":"12","author":"Solis-Lemus","year":"2016","journal-title":"PLoS Genet"},{"issue":"pt 2","key":"bib108","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1099\/vir.0.83057-0","article-title":"Evidence of frequent recombination among human adenoviruses","volume":"89","author":"Lukashev","year":"2008","journal-title":"J Gen Virol"},{"key":"bib109","doi-asserted-by":"publisher","first-page":"2178","DOI":"10.3389\/fmicb.2018.02178","article-title":"Adenoviromics: mining the human adenovirus species D genome","volume":"9","author":"Ismail","year":"2018","journal-title":"Front Microbiol"},{"issue":"2","key":"bib110","doi-asserted-by":"publisher","first-page":"veac067","DOI":"10.1093\/ve\/veac067","article-title":"High genetic stability of co-circulating human adenovirus type 31 lineages over 59 years","volume":"8","author":"Gotting","year":"2022","journal-title":"Virus Evol"},{"issue":"2","key":"bib111","doi-asserted-by":"publisher","first-page":"veac098","DOI":"10.1093\/ve\/veac098","article-title":"Molecular phylogeny of human adenovirus type 41 lineages","volume":"8","author":"Gotting","year":"2022","journal-title":"Virus Evol"},{"key":"bib69","volume-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2021"},{"key":"bib70","volume-title":"RStudio: Integrated Development for R","author":"RStudio Team","year":"2020"},{"key":"bib78","volume-title":"Updated unified nomenclature system for the highly pathogenic H5N1 avian influenza viruses [press release]","author":"WHO Global Influenza Surveillance and Response System (GISRS)","year":"2011"}],"container-title":["Investigative Opthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2793352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:47Z","timestamp":1791927107000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2793352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,6]]},"references-count":111,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.65.2.12","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2,6]]}}}