{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:01:25Z","timestamp":1791928885333,"version":"4.3.4"},"reference-count":80,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"4","license":[{"start":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T00:00:00Z","timestamp":1714348800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2024,4,29]]},"DOI":"10.1167\/iovs.65.4.42","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T13:02:12Z","timestamp":1716296532000},"page":"42","source":"Crossref","is-referenced-by-count":4,"title":["miR-26 Deficiency Causes Alterations in Lens Transcriptome and Results in Adult-Onset Cataract"],"prefix":"10.1167","volume":"65","author":[{"given":"Anil","family":"Upreti","sequence":"first","affiliation":[{"name":"Cell, Molecular and Structural Biology Program, Miami University, Oxford, Ohio, United States"},{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh V.","family":"Hoang","sequence":"additional","affiliation":[{"name":"Cell, Molecular and Structural Biology Program, Miami University, Oxford, Ohio, United States"},{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghua","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared A.","family":"Tangeman","sequence":"additional","affiliation":[{"name":"Cell, Molecular and Structural Biology Program, Miami University, Oxford, Ohio, United States"},{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Dierker","sequence":"additional","affiliation":[{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad D.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis A.","family":"Tsonis","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Dayton, Dayton, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salil A.","family":"Lachke","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, University of Delaware, Newark, Delaware, United States"},{"name":"Center for Bioinformatics and Computational Biology, University of Delaware, Newark, Delaware, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Cell, Molecular and Structural Biology Program, Miami University, Oxford, Ohio, United States"},{"name":"Department of Biology and Center for Visual Sciences, Miami University, Oxford, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"10","key":"bib1","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.tig.2017.08.001","article-title":"Signaling and gene regulatory networks in mammalian lens development","volume":"33","author":"Cvekl","year":"2017","journal-title":"Trends Genet"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"108889","DOI":"10.1016\/j.exer.2021.108889","article-title":"RNA-binding proteins and post-transcriptional regulation in lens biology and cataract: mediating spatiotemporal expression of key factors that control the cell cycle, transcription, cytoskeleton and transparency","volume":"214","author":"Lachke","year":"2022","journal-title":"Exp Eye Res"},{"issue":"9","key":"bib3","doi-asserted-by":"publisher","first-page":"2388","DOI":"10.1002\/dvdy.v238:9","article-title":"Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development","volume":"238","author":"Li","year":"2009","journal-title":"Dev Dyn"},{"issue":"3","key":"bib4","doi-asserted-by":"publisher","first-page":"e1003357","DOI":"10.1371\/journal.pgen.1003357","article-title":"Pax6 regulates gene expression in the vertebrate lens through miR-204","volume":"9","author":"Shaham","year":"2013","journal-title":"PLoS Genet"},{"issue":"3","key":"bib5","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1261\/rna.2183803","article-title":"A uniform system for microRNA annotation","volume":"9","author":"Ambros","year":"2003","journal-title":"RNA"},{"issue":"Database issue","key":"bib6","doi-asserted-by":"crossref","first-page":"D68","DOI":"10.1093\/nar\/gkt1181","article-title":"miRBase: annotating high confidence microRNAs using deep sequencing data","volume":"42","author":"Kozomara","year":"2014","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"bib7","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1261\/rna.048132.114","article-title":"Concordant dysregulation of miR-5p and miR-3p arms of the same precursor microRNA may be a mechanism in inducing cell proliferation and tumorigenesis: a lung cancer study","volume":"21","author":"Mitra","year":"2015","journal-title":"RNA"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"106417","DOI":"10.1016\/j.phrs.2022.106417","article-title":"Noncoding RNAs in cataract formation: star molecules emerge in an endless stream","volume":"184","author":"Chen","year":"2022","journal-title":"Pharmacol Res"},{"issue":"1","key":"bib9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00418-005-0139-0","article-title":"miRNA and Dicer in the mammalian lens: expression of brain-specific miRNAs in the lens","volume":"126","author":"Frederikse","year":"2006","journal-title":"Histochem Cell Biol"},{"issue":"1","key":"bib10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2164-11-715","article-title":"miRNeye: a microRNA expression atlas of the mouse eye","volume":"11","author":"Karali","year":"2010","journal-title":"BMC Genomics"},{"issue":"2","key":"bib11","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1167\/iovs.06-0866","article-title":"Identification and characterization of microRNAs expressed in the mouse eye","volume":"48","author":"Karali","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib12","first-page":"1175","article-title":"MicroRNAs of the mammalian eye display distinct and overlapping tissue specificity","volume":"12","author":"Ryan","year":"2006","journal-title":"Mol Vis"},{"issue":"12","key":"bib13","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1534\/g3.113.008698","article-title":"Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation","volume":"3","author":"Wolf","year":"2013","journal-title":"G3"},{"issue":"35","key":"bib14","doi-asserted-by":"publisher","first-page":"15491","DOI":"10.1073\/pnas.0914785107","article-title":"miR-204 is required for lens and retinal development via Meis2 targeting","volume":"107","author":"Conte","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"bib15","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/j.exer.2008.03.004","article-title":"Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11","volume":"86","author":"Wurm","year":"2008","journal-title":"Exp Eye Res"},{"issue":"7","key":"bib16","doi-asserted-by":"publisher","first-page":"e1004491","DOI":"10.1371\/journal.pgen.1004491","article-title":"Sox11 is required to maintain proper levels of Hedgehog signaling during vertebrate ocular morphogenesis","volume":"10","author":"Pillai-Kastoori","year":"2014","journal-title":"PLoS Genet"},{"issue":"12","key":"bib17","doi-asserted-by":"publisher","first-page":"7163","DOI":"10.1167\/iovs.13-12687","article-title":"Ocular phenotype of Fbn2-null mice","volume":"54","author":"Shi","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib18","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1167\/iovs.12-10904","article-title":"MicroRNA-204-5p regulates epithelial-to-mesenchymal transition during human posterior capsule opacification by targeting SMAD4","volume":"54","author":"Wang","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib19","doi-asserted-by":"publisher","first-page":"528","DOI":"10.2119\/molmed.2011.00463","article-title":"Implication of the miR-184 and miR-204 competitive RNA network in control of mouse secondary cataract","volume":"18","author":"Hoffmann","year":"2012","journal-title":"Mol Med"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"615761","DOI":"10.3389\/fcell.2021.615761","article-title":"Genome-wide analysis of differentially expressed miRNAs and their associated regulatory networks in lenses deficient for the congenital cataract-linked Tudor domain containing protein TDRD7","volume":"9","author":"Anand","year":"2021","journal-title":"Front Cell Dev Biol"},{"issue":"5","key":"bib21","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1136\/bjophthalmol-2011-300585","article-title":"MicroRNAs and cataracts: correlation among let-7 expression, age and the severity of lens opacity","volume":"96","author":"Peng","year":"2012","journal-title":"Br J Ophthalmol"},{"issue":"7","key":"bib22","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1038\/eye.2013.90","article-title":"Correlation between microRNA-34a levels and lens opacity severity in age-related cataracts","volume":"27","author":"Chien","year":"2013","journal-title":"EYE"},{"issue":"7","key":"bib23","doi-asserted-by":"publisher","first-page":"3906","DOI":"10.1167\/iovs.11-9178","article-title":"Discrepant expression of microRNAs in transparent and cataractous human lenses","volume":"53","author":"Wu","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12, pt A","key":"bib24","doi-asserted-by":"publisher","first-page":"2439","DOI":"10.1016\/j.bbadis.2014.10.002","article-title":"MicroRNA-125b inhibits lens epithelial cell apoptosis by targeting p53 in age-related cataract","volume":"1842","author":"Qin","year":"2014","journal-title":"Biochim Biophys Acta"},{"issue":"8","key":"bib25","doi-asserted-by":"publisher","first-page":"4919","DOI":"10.1167\/iovs.14-16253","article-title":"Transcriptome profiling of developing murine lens through RNA sequencing","volume":"56","author":"Khan","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"bib26","doi-asserted-by":"publisher","first-page":"812","DOI":"10.3109\/02713683.2010.489182","article-title":"Genomic profiling of miRNAs in two human lens cell lines","volume":"35","author":"Tian","year":"2010","journal-title":"Curr Eye Res"},{"issue":"8","key":"bib27","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1038\/s41587-019-0201-4","article-title":"Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype","volume":"37","author":"Kim","year":"2019","journal-title":"Nat Biotechnol"},{"issue":"3","key":"bib28","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1038\/nbt.3122","article-title":"StringTie enables improved reconstruction of a transcriptome from RNA-seq reads","volume":"33","author":"Pertea","year":"2015","journal-title":"Nat Biotechnol"},{"issue":"12","key":"bib29","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"issue":"1","key":"bib30","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1093\/nar\/gkr688","article-title":"miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades","volume":"40","author":"Friedl\u00e4nder","year":"2012","journal-title":"Nucleic Acids Res"},{"issue":"W1","key":"bib31","doi-asserted-by":"publisher","first-page":"W207","DOI":"10.1093\/nar\/gkad347","article-title":"g:Profiler-interoperable web service for functional enrichment analysis and gene identifier mapping (2023 update)","volume":"51","author":"Kolberg","year":"2023","journal-title":"Nucleic Acids Res"},{"issue":"W1","key":"bib32","doi-asserted-by":"publisher","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"bib33","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang","year":"2009","journal-title":"Nat Protoc"},{"issue":"10","key":"bib35","doi-asserted-by":"publisher","first-page":"e0206239","DOI":"10.1371\/journal.pone.0206239","article-title":"miRWalk: an online resource for prediction of microRNA binding sites","volume":"13","author":"Sticht","year":"2018","journal-title":"PLoS One"},{"issue":"6472","key":"bib36","doi-asserted-by":"publisher","first-page":"eaav1741","DOI":"10.1126\/science.aav1741","article-title":"The biochemical basis of microRNA targeting efficacy","volume":"366","author":"McGeary","year":"2019","journal-title":"Science"},{"issue":"43","key":"bib37","doi-asserted-by":"publisher","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3","key":"bib38","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1038\/ng1180","article-title":"PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes","volume":"34","author":"Mootha","year":"2003","journal-title":"Nat Genet"},{"key":"bib39","first-page":"2007","article-title":"Cat-Map: putting cataract on the map","volume":"16","author":"Shiels","year":"2010","journal-title":"Mol Vis"},{"issue":"D1","key":"bib40","doi-asserted-by":"publisher","first-page":"D875","DOI":"10.1093\/nar\/gkx837","article-title":"iSyTE 2.0: a database for expression-based gene discovery in the eye","volume":"46","author":"Kakrana","year":"2018","journal-title":"Nucleic Acids Res"},{"issue":"8","key":"bib41","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1038\/cdd.2016.152","article-title":"MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1\/Notch signaling pathway","volume":"24","author":"Chen","year":"2017","journal-title":"Cell Death Differ"},{"issue":"1","key":"bib42","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.cmet.2013.11.015","article-title":"Argonaute2 mediates compensatory expansion of the pancreatic \u00df cell","volume":"19","author":"Tattikota","year":"2014","journal-title":"Cell Metab"},{"issue":"10","key":"bib43","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/j.febslet.2015.03.010","article-title":"MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization","volume":"589","author":"Takahashi","year":"2015","journal-title":"FEBS Lett"},{"issue":"5","key":"bib44","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.stem.2010.02.017","article-title":"Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation","volume":"6","author":"Liu","year":"2010","journal-title":"Cell Stem Cell"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"e01323","DOI":"10.7554\/eLife.01323","article-title":"microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart","volume":"2","author":"Heidersbach","year":"2013","journal-title":"Elife"},{"key":"bib46","first-page":"1491","article-title":"Comparative transcriptome analysis of epithelial and fiber cells in newborn mouse lenses with RNA sequencing","volume":"20","author":"Hoang","year":"2014","journal-title":"Mol Vis"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.omto.2022.04.001","article-title":"CRISPR-Cas knockout of miR21 reduces glioma growth","volume":"25","author":"Nieland","year":"2022","journal-title":"Mol Ther Oncolytics"},{"issue":"2","key":"bib48","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1101\/lm.039578.115","article-title":"Targeted deletion of miR-132\/-212 impairs memory and alters the hippocampal transcriptome","volume":"23","author":"Hansen","year":"2016","journal-title":"Learn Mem"},{"issue":"4","key":"bib49","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1038\/s41419-022-04721-z","article-title":"Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits","volume":"13","author":"Fu","year":"2022","journal-title":"Cell Death Dis"},{"issue":"1","key":"bib50","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s12863-021-00976-1","article-title":"Transcriptome signature of miRNA-26b KO mouse model suggests novel targets","volume":"22","author":"van der Vorst","year":"2021","journal-title":"BMC Genom Data"},{"issue":"2","key":"bib51","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.ydbio.2012.05.022","article-title":"Parallels between neuron and lens fiber cell structure and molecular regulatory networks","volume":"368","author":"Frederikse","year":"2012","journal-title":"Dev Biol"},{"issue":"1","key":"bib52","doi-asserted-by":"publisher","first-page":"41","DOI":"10.3109\/02713683.2014.997886","article-title":"Moonlighting\u201d GAPDH protein localizes with AMPA receptor GluA2 and L1 axonal cell adhesion molecule at fiber cell borders in the lens","volume":"41","author":"Frederikse","year":"2016","journal-title":"Curr Eye Res"},{"issue":"11","key":"bib53","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1007\/s11064-015-1702-2","article-title":"Fragile X syndrome FMRP co-localizes with regulatory targets PSD-95, GABA receptors, CaMKIIa, and mGluR5 at fiber cell membranes in the eye lens","volume":"40","author":"Frederikse","year":"2015","journal-title":"Neurochem Res"},{"issue":"6","key":"bib54","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/j.mehy.2015.03.008","article-title":"Lens GABA receptors are a target of GABA-related agonists that mitigate experimental myopia","volume":"84","author":"Frederikse","year":"2015","journal-title":"Med Hypotheses"},{"issue":"1\u20132","key":"bib55","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0925-4773(00)00301-4","article-title":"Nestin expression during mouse eye and lens development","volume":"94","author":"Yang","year":"2000","journal-title":"Mech Dev"},{"key":"bib56","first-page":"2301","article-title":"HuB\/C\/D, nPTB, REST4, and miR-124 regulators of neuronal cell identity are also utilized in the lens","volume":"16","author":"Bitel","year":"2010","journal-title":"Mol Vis"},{"issue":"2","key":"bib57","doi-asserted-by":"publisher","first-page":"e1733","DOI":"10.1002\/wrna.v14.2","article-title":"Regulation of neuronal RNA signatures by ELAV\/Hu proteins","volume":"14","author":"Hilgers","year":"2023","journal-title":"Wiley Interdiscip Rev RNA"},{"issue":"1","key":"bib58","doi-asserted-by":"publisher","first-page":"2203","DOI":"10.1038\/s41598-021-81611-y","article-title":"Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract","volume":"11","author":"Maddala","year":"2021","journal-title":"Sci Rep"},{"issue":"1","key":"bib59","doi-asserted-by":"publisher","first-page":"dev202249","DOI":"10.1242\/dev.202249","article-title":"Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology","volume":"151","author":"Tangeman","year":"2024","journal-title":"Development"},{"issue":"1568","key":"bib60","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1098\/rstb.2010.0341","article-title":"The lens as a model for fibrotic disease","volume":"366","author":"Eldred","year":"2011","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"886053","DOI":"10.3389\/fcell.2022.886053","article-title":"Lens fibrosis: understanding the dynamics of cell adhesion signaling in lens epithelial-mesenchymal transition","volume":"10","author":"Taiyab","year":"2022","journal-title":"Front Cell Dev Biol"},{"issue":"3","key":"bib62","doi-asserted-by":"publisher","first-page":"501","DOI":"10.3390\/cells12030501","article-title":"Lens epithelial explants treated with vitreous humor undergo alterations in chromatin landscape with concurrent activation of genes associated with fiber cell differentiation and innate immune response","volume":"12","author":"Upreti","year":"2023","journal-title":"Cells"},{"key":"bib63","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.exer.2015.02.004","article-title":"Fibrosis in the lens. Sprouty regulation of TGF\u00df-signaling prevents lens EMT leading to cataract","volume":"142","author":"Lovicu","year":"2016","journal-title":"Exp Eye Res"},{"key":"bib64","doi-asserted-by":"publisher","first-page":"107693","DOI":"10.1016\/j.exer.2019.107693","article-title":"Enhanced EGF receptor-signaling potentiates TGF\u00df-induced lens epithelial-mesenchymal transition","volume":"185","author":"Shu","year":"2019","journal-title":"Exp Eye Res"},{"issue":"1","key":"bib65","doi-asserted-by":"publisher","first-page":"2876","DOI":"10.1038\/s41467-019-10753-5","article-title":"The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression","volume":"10","author":"Huang","year":"2019","journal-title":"Nat Commun"},{"issue":"2","key":"bib66","doi-asserted-by":"publisher","first-page":"256","DOI":"10.2337\/db17-0506","article-title":"miR-204 controls glucagon-like peptide 1 receptor expression and agonist function","volume":"67","author":"Jo","year":"2018","journal-title":"Diabetes"},{"issue":"7","key":"bib67","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1681\/ASN.2019101100","article-title":"Endogenous miR-204 protects the kidney against chronic injury in hypertension and diabetes","volume":"31","author":"Cheng","year":"2020","journal-title":"J Am Soc Nephrol"},{"issue":"4","key":"bib68","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1111\/cge.v104.4","article-title":"MIR204 n.37C>T variant as a cause of chorioretinal dystrophy variably associated with iris coloboma, early-onset cataracts and congenital glaucoma","volume":"104","author":"Jedlickova","year":"2023","journal-title":"Clin Genet"},{"issue":"7048","key":"bib69","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1038\/nature03817","article-title":"Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis","volume":"436","author":"Zhao","year":"2005","journal-title":"Nature"},{"issue":"2","key":"bib70","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/ng1725","article-title":"The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation","volume":"38","author":"Chen","year":"2006","journal-title":"Nat Genet"},{"issue":"2","key":"bib71","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1089\/scd.2010.0283","article-title":"MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4","volume":"20","author":"Xie","year":"2011","journal-title":"Stem Cells Dev"},{"issue":"2","key":"bib72","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.cell.2007.03.030","article-title":"Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2","volume":"129","author":"Zhao","year":"2007","journal-title":"Cell"},{"issue":"5","key":"bib73","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1016\/j.ajhg.2011.09.014","article-title":"Mutation altering the miR-184 seed region causes familial keratoconus with cataract","volume":"89","author":"Hughes","year":"2011","journal-title":"Am J Hum Genet"},{"issue":"3","key":"bib74","doi-asserted-by":"publisher","first-page":"244","DOI":"10.3109\/13816810.2013.848908","article-title":"C.57 C >T mutation in MIR 184 is responsible for congenital cataracts and corneal abnormalities in a five-generation family from Galicia, Spain","volume":"36","author":"Bykhovskaya","year":"2015","journal-title":"Ophthalmic Genet"},{"issue":"1","key":"bib75","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/2008-322X.180715","article-title":"Screening for MIR184 mutations in Iranian patients with keratoconus","volume":"11","author":"Farzadfard","year":"2016","journal-title":"J Ophthalmic Vis Res"},{"issue":"1","key":"bib76","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1167\/iovs.11-8783","article-title":"A single-base substitution in the seed region of miR-184 causes EDICT syndrome","volume":"53","author":"Iliff","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"bib77","doi-asserted-by":"publisher","first-page":"e22927","DOI":"10.1096\/fsb2.v37.5","article-title":"Knockout of miR-184 in zebrafish leads to ocular abnormalities by elevating p21 levels","volume":"37","author":"Zhang","year":"2023","journal-title":"FASEB J"},{"issue":"6","key":"bib78","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1016\/j.stemcr.2017.10.030","article-title":"microRNA-184 induces a commitment switch to epidermal differentiation","volume":"9","author":"Nagosa","year":"2017","journal-title":"Stem Cell Rep"},{"issue":"8","key":"bib79","doi-asserted-by":"publisher","first-page":"5266","DOI":"10.1167\/iovs.13-12035","article-title":"Mutational analysis of MIR184 in sporadic keratoconus and myopia","volume":"54","author":"Lechner","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"bib80","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.cub.2009.12.051","article-title":"Many families of C. elegans microRNAs are not essential for development or viability","volume":"20","author":"Alvarez-Saavedra","year":"2010","journal-title":"Curr Biol"},{"key":"bib34","article-title":"Venny: an interactive tool for comparing lists with Venn's diagrams. Venny 2.1","author":"Oliveros"}],"container-title":["Investigative Ophthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2793614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:31:54Z","timestamp":1791927114000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2793614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,29]]},"references-count":80,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.65.4.42","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.01.29.577818","asserted-by":"object"}]},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4,29]]}}}