{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:01:55Z","timestamp":1791928915915,"version":"4.3.4"},"reference-count":71,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"11","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2025,8,19]]},"DOI":"10.1167\/iovs.66.11.44","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T15:01:13Z","timestamp":1755615673000},"page":"44","source":"Crossref","is-referenced-by-count":3,"title":["Relationship Between Diurnal Variations of Episcleral Venous Pressure and Intraocular Pressure"],"prefix":"10.1167","volume":"66","author":[{"given":"Arash","family":"Kazemi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uttio","family":"Roy Chowdhury","sequence":"additional","affiliation":[{"name":"Qlaris Bio, Inc., Dedham, Massachusetts, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Fautsch","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thurein M.","family":"Htoo","sequence":"additional","affiliation":[{"name":"Qlaris Bio, Inc., Dedham, Massachusetts, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara M.","family":"Wirostko","sequence":"additional","affiliation":[{"name":"Qlaris Bio, Inc., Dedham, Massachusetts, United States"},{"name":"Department of Ophthalmology, Moran Eye Center, University of Utah, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David O.","family":"Hodge","sequence":"additional","affiliation":[{"name":"Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur J.","family":"Sit","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1016\/S0140-6736(04)16257-0","article-title":"Primary open-angle glaucoma","volume":"363","author":"Weinreb","year":"2004","journal-title":"Lancet"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/0002-9394(63)92431-0","article-title":"Influence of position on intraocular pressure","volume":"55","author":"Galin","year":"1963","journal-title":"Am J Ophthalmol"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1097\/00006324-199708000-00028","article-title":"Does the change of anterior chamber depth or\/and episcleral venous pressure cause intraocular pressure change in postural variation?","volume":"74","author":"Lam","year":"1997","journal-title":"Optom Vis Sci"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"7215","DOI":"10.1167\/iovs.13-12441","article-title":"Correlation between biomechanical responses of posterior sclera and IOP elevations during micro intraocular volume change","volume":"54","author":"Morris","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib5","first-page":"204","article-title":"The influence of position on intraocular pressure","volume":"12","author":"Anderson","year":"1973","journal-title":"Invest Ophthalmol"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/0002-9394(84)90698-6","article-title":"Effect of inverted body position on intraocular pressure","volume":"98","author":"Weinreb","year":"1984","journal-title":"Am J Ophthalmol"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1136\/bjo.2005.070649","article-title":"The relation between intraocular pressure peak in the water drinking test and visual field progression in glaucoma","volume":"89","author":"Susanna","year":"2005","journal-title":"Br J Ophthalmol"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"5313","DOI":"10.1167\/iovs.13-11792","article-title":"Intraocular pressure change over a habitual 24-hour period after changing posture or drinking water and related factors in normal tension glaucoma","volume":"54","author":"Sakata","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1002\/j.2040-4603.2015.tb00603.x","article-title":"Autonomic control of the eye","volume":"5","author":"McDougal","year":"2015","journal-title":"Compr Physiol"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1136\/bjo.35.5.291","article-title":"Anatomical study of Schlemm's canal and aqueous veins by means of neoprene casts. Part I. Aqueous veins","volume":"35","author":"Ashton","year":"1951","journal-title":"Br J Ophthalmol"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1136\/bjo.36.5.265","article-title":"Anatomical study of Schlemm's canal and aqueous veins by means of neoprene casts. II. Aqueous veins","volume":"36","author":"Ashton","year":"1952","journal-title":"Br J Ophthalmol"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1136\/bjo.37.10.577","article-title":"Anatomical study of Schlemm's canal and aqueous veins by means of neoprene casts. III. Arterial relations of Schlemm's canal","volume":"37","author":"Ashton","year":"1953","journal-title":"Br J Ophthalmol"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1097\/00061198-199802000-00010","article-title":"Arteriovenous anastomoses of the episcleral vasculature in the rabbit and rat eye","volume":"7","author":"Selbach","year":"1998","journal-title":"J Glaucoma"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1080\/02713680590934076","article-title":"Angioarchitecture and innervation of the primate anterior episclera","volume":"30","author":"Selbach","year":"2005","journal-title":"Curr Eye Res"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"6860","DOI":"10.1167\/iovs.13-12781","article-title":"Episcleral venous pressure and IOP responses to central electrical stimulation in the rat","volume":"54","author":"Strohmaier","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1001\/archopht.1983.01040020449024","article-title":"A practical venomanometer. Measurement of episcleral venous pressure and assessment of the normal range","volume":"101","author":"Zeimer","year":"1983","journal-title":"Arch Ophthalmol"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0002-9394(14)76662-0","article-title":"Measurement of episcleral venous pressure","volume":"85","author":"Phelps","year":"1978","journal-title":"Am J Ophthalmol"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1097\/00061198-200102000-00005","article-title":"Diurnal variation of episcleral venous pressure in healthy patients: a pilot study","volume":"10","author":"Blondeau","year":"2001","journal-title":"J Glaucoma"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1097\/00061198-200308000-00013","article-title":"Episcleral venous pressure in younger and older subjects in the sitting and supine positions","volume":"12","author":"Sultan","year":"2003","journal-title":"J Glaucoma"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.exer.2011.05.003","article-title":"Measurement of episcleral venous pressure","volume":"93","author":"Sit","year":"2011","journal-title":"Exp Eye Res"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"5151","DOI":"10.1167\/iovs.17-22154","article-title":"Effect of body position on epsicleral venous pressure in healthy subjects","volume":"58","author":"Arora","year":"2017","journal-title":"Invest Ophth Vis Sci"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1167\/iovs.62.13.4","article-title":"Effect of topical phenylephrine 2.5% on episcleral venous pressure in normal human eyes","volume":"62","author":"Kazemi","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1089\/jop.2017.0138","article-title":"The effects of netarsudil ophthalmic solution on aqueous humor dynamics in a randomized study in humans","volume":"34","author":"Kazemi","year":"2018","journal-title":"J Ocul Pharmacol Ther"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/S0002-9394(14)74275-8","article-title":"Intraocular and episcleral venous pressure increase during inverted posture","volume":"103","author":"Friberg","year":"1987","journal-title":"Am J Ophthalmol"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1159\/000088378","article-title":"Episcleral venous pressure in untreated primary open-angle and normal-tension glaucoma","volume":"219","author":"Selbach","year":"2005","journal-title":"Ophthalmologica"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1136\/bjo.47.5.271","article-title":"Episcleral venous pressure in tonography","volume":"47","author":"Leith","year":"1963","journal-title":"Br J Ophthalmol"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1097\/00007611-197511000-00026","article-title":"Glaucoma with elevated episcleral venous pressure","volume":"68","author":"Bigger","year":"1975","journal-title":"South Med J"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1097\/00061198-200004000-00012","article-title":"Glaucoma associated with elevated episcleral venous pressure","volume":"9","author":"Greenfield","year":"2000","journal-title":"J Glaucoma"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1177\/112067210001000308","article-title":"Ocular findings in Sturge-Weber syndrome","volume":"10","author":"Celebi","year":"2000","journal-title":"Eur J Ophthalmol"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/BF00419376","article-title":"[The influence of changes in body position on intraocular pressure, episcleral venous pressure, and blood pressure (author's transl)]","volume":"208","author":"Kaskel","year":"1978","journal-title":"Albrecht Von Graefes Arch Klin Exp Ophthalmol"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/0002-9394(86)90022-X","article-title":"Portable transducer for measurement of episcleral venous pressure","volume":"102","author":"Friberg","year":"1986","journal-title":"Am J Ophthalmol"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.exer.2011.03.018","article-title":"A novel method for computerized measurement of episcleral venous pressure in humans","volume":"92","author":"Sit","year":"2011","journal-title":"Exp Eye Res"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1089\/jop.2024.0112","article-title":"Understanding individual intraocular pressure response to treatment with latanoprost and timolol.","volume":"41","author":"Reitinger","year":"2025","journal-title":"J Ocul Pharmacol Ther"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.ajo.2021.01.019","article-title":"Netarsudil Improves Trabecular outflow facility in patients with primary open angle glaucoma or ocular hypertension: a Phase 2 study","volume":"226","author":"Sit","year":"2021","journal-title":"Am J Ophthalmol"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1038\/hr.2016.41","article-title":"Mean arterial pressure values calculated using seven different methods and their associations with target organ deterioration in a single-center study of 1878 individuals","volume":"39","author":"Papaioannou","year":"2016","journal-title":"Hypertens Res"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1089\/108076803322279354","article-title":"Laboratory assessment of diurnal and nocturnal ocular perfusion pressures in humans","volume":"19","author":"Liu","year":"2003","journal-title":"J Ocul Pharmacol Ther"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.2307\/2531734","article-title":"Models for longitudinal data: a generalized estimating equation approach","volume":"44","author":"Zeger","year":"1988","journal-title":"Biometrics"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.exer.2013.03.020","article-title":"Effects of head down tilt on episcleral venous pressure in a rabbit model","volume":"111","author":"Lavery","year":"2013","journal-title":"Exp Eye Res"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3109\/02713689609017615","article-title":"Short-term hemodynamic changes in episcleral arteriovenous anastomoses correlate with venous pressure and IOP changes in the albino rabbit","volume":"15","author":"Funk","year":"1996","journal-title":"Curr Eye Res"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"108348","DOI":"10.1016\/j.exer.2020.108348","article-title":"Increased episcleral venous pressure in a mouse model of circumlimbal suture induced ocular hypertension","volume":"202","author":"Wong","year":"2021","journal-title":"Exp Eye Res"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1001\/archopht.1963.00960040758013","article-title":"Diurnal variation of intraocular pressure in the normal eye","volume":"69","author":"De Venecia","year":"1963","journal-title":"Arch Ophthalmol"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1001\/archopht.1960.01840010496004","article-title":"The significance of the diurnal tension variations in normal and glaucomatous eyes","volume":"64","author":"Drance","year":"1960","journal-title":"Arch Ophthalmol"},{"key":"bib45","first-page":"2707","article-title":"Nocturnal elevation of intraocular pressure in young adults","volume":"39","author":"Liu","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib46","first-page":"2912","article-title":"Twenty-four-hour pattern of intraocular pressure in the aging population","volume":"40","author":"Liu","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1167\/iovs.02-0666","article-title":"Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changes","volume":"44","author":"Liu","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1016\/0002-9394(65)93016-3","article-title":"Diurnal tonography in normal and glaucomatous eyes","volume":"59","author":"Newell","year":"1965","journal-title":"Am J Ophthalmol"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1159\/000027290","article-title":"Fluctuations of intraocular pressure during the day in open-angle glaucoma, normal-tension glaucoma and normal subjects","volume":"212","author":"Sacca","year":"1998","journal-title":"Ophthalmologica"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1016\/S0161-6420(93)31551-4","article-title":"Individual variability in the diurnal intraocular pressure curve","volume":"100","author":"Wilensky","year":"1993","journal-title":"Ophthalmology"},{"key":"bib51","doi-asserted-by":"publisher","first-page":"5121","DOI":"10.1167\/iovs.11-7364","article-title":"Diurnal variations in axial length, choroidal thickness, intraocular pressure, and ocular biometrics","volume":"52","author":"Chakraborty","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"2911","DOI":"10.1167\/iovs.08-1833","article-title":"Diurnal variation of axial length, intraocular pressure, and anterior eye biometrics","volume":"49","author":"Read","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib53","first-page":"7623","article-title":"Circadian variation of aqueous humor dynamics in older healthy adults","volume":"54","author":"Nau","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1097\/OPX.0b013e3181981b7e","article-title":"Diurnal variation of corneal shape and thickness","volume":"86","author":"Read","year":"2009","journal-title":"Optom Vis Sci"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1097\/00006324-198212000-00007","article-title":"Diurnal variations of corneal topography and thickness","volume":"59","author":"Kiely","year":"1982","journal-title":"Am J Optom Physiol Opt"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1136\/bjo.80.12.1068","article-title":"Diurnal variations in human corneal thickness","volume":"80","author":"Harper","year":"1996","journal-title":"Br J Ophthalmol"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1097\/00003226-200107000-00008","article-title":"Diurnal variation of corneal and corneal epithelial thickness measured using optical coherence tomography","volume":"20","author":"Feng","year":"2001","journal-title":"Cornea"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/00003226-200304000-00004","article-title":"Diurnal variation of corneal sensitivity and thickness","volume":"22","author":"du Toit","year":"2003","journal-title":"Cornea"},{"key":"bib59","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3928\/1081-597X-20020101-09","article-title":"Diurnal variation of human corneal curvature in young adults","volume":"18","author":"Handa","year":"2002","journal-title":"J Refract Surg"},{"key":"bib60","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1097\/01.ico.0000154385.43732.6e","article-title":"The diurnal variation of corneal topography and aberrations","volume":"24","author":"Read","year":"2005","journal-title":"Cornea"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1097\/IJG.0b013e31802b350f","article-title":"Diurnal variation of central corneal thickness and Goldmann applanation tonometry estimates of intraocular pressure","volume":"16","author":"Hamilton","year":"2007","journal-title":"J Glaucoma"},{"key":"bib62","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/S0039-6257(00)00110-7","article-title":"Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach","volume":"44","author":"Doughty","year":"2000","journal-title":"Surv Ophthalmol"},{"key":"bib63","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1001\/jamaophthalmol.2018.1746","article-title":"Association between 24-hour intraocular pressure monitored with contact lens sensor and visual field progression in older adults with glaucoma","volume":"136","author":"De Moraes","year":"2018","journal-title":"JAMA Ophthalmol"},{"key":"bib64","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1097\/00061198-200004000-00002","article-title":"Large diurnal fluctuations in intraocular pressure are an independent risk factor in patients with glaucoma","volume":"9","author":"Asrani","year":"2000","journal-title":"J Glaucoma"},{"key":"bib65","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1016\/j.ophtha.2007.10.031","article-title":"Intraocular pressure fluctuation a risk factor for visual field progression at low intraocular pressures in the advanced glaucoma intervention study","volume":"115","author":"Caprioli","year":"2008","journal-title":"Ophthalmology"},{"key":"bib66","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1016\/j.jcjo.2014.07.008","article-title":"Intraocular pressure variations: causes and clinical significance","volume":"49","author":"Sit","year":"2014","journal-title":"Can J Ophthalmol"},{"key":"bib67","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/S0161-6420(95)31000-7","article-title":"Effects of apraclonidine on aqueous humor dynamics in human eyes","volume":"102","author":"Toris","year":"1995","journal-title":"Ophthalmology"},{"key":"bib68","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1167\/iovs.63.2.15","article-title":"Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models","volume":"63","author":"Roy Chowdhury","year":"2022","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib69","doi-asserted-by":"publisher","first-page":"5731","DOI":"10.1167\/iovs.17-22538","article-title":"Effect of cromakalim prodrug 1 (CKLP1) on aqueous humor dynamics and feasibility of combination therapy with existing ocular hypotensive agents","volume":"58","author":"Roy Chowdhury","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib70","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1167\/iovs.09-4530","article-title":"Episcleral venous pressure responses to topical nitroprusside and N-Nitro-L-arginine methyl ester","volume":"51","author":"Zamora","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib71","doi-asserted-by":"publisher","first-page":"108766","DOI":"10.1016\/j.exer.2021.108766","article-title":"Episcleral venous pressure response to brain stem stimulation: effect of topical lidocaine","volume":"212","author":"Strohmaier","year":"2021","journal-title":"Exp Eye Res"},{"key":"bib28","first-page":"1127","article-title":"Glaucoma secondary to elevated episcleral venous pressure","volume-title":"The Glaucomas","author":"Weinreb","year":"1989"},{"key":"bib38","first-page":"97","article-title":"Physiological aspects of the circulation in the optic nerve","volume-title":"Glaucoma: Conceptions of a Disease","author":"Bill","year":"1978"}],"container-title":["Investigative Ophthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2810690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:05Z","timestamp":1791927125000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2810690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,19]]},"references-count":71,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,8,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.66.11.44","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,19]]}}}