{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:01:28Z","timestamp":1791928888444,"version":"4.3.4"},"reference-count":25,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"15","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2025,12,18]]},"DOI":"10.1167\/iovs.66.15.59","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T13:01:00Z","timestamp":1766062860000},"page":"59","source":"Crossref","is-referenced-by-count":0,"title":["Obstructive Sleep Apnea Accelerates Progression of Intermediate Age-Related Macular Degeneration: A Three-Year Prospective Cohort Study"],"prefix":"10.1167","volume":"66","author":[{"given":"Qiang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyue","family":"Liu","sequence":"additional","affiliation":[{"name":"The Second Clinical Medical College, Jinan University, Luohu District, Shenzhen, Guangdong, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Second Clinical Medical College, Jinan University, Luohu District, Shenzhen, Guangdong, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"1","key":"bib1","doi-asserted-by":"publisher","first-page":"3510","DOI":"10.1186\/s12889-024-21047-x","article-title":"Global burden of low vision and blindness due to age-related macular degeneration from 1990 to 2021 and projections for 2050","volume":"24","author":"Zhang","year":"2024","journal-title":"BMC Public Health"},{"issue":"2","key":"bib2","doi-asserted-by":"publisher","first-page":"020703","DOI":"10.7189\/jogh.07.020703","article-title":"The national and subnational prevalence and burden of age\u2013related macular degeneration in China","volume":"7","author":"Song","year":"2017","journal-title":"J Glob Health"},{"issue":"3","key":"bib3","doi-asserted-by":"publisher","first-page":"e0119829","DOI":"10.1371\/journal.pone.0119829","article-title":"Prevalence of obstructive sleep apnea syndrome and CPAP adherence in the elderly Chinese population","volume":"10","author":"Ng","year":"2015","journal-title":"PLoS One"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"425","DOI":"10.3390\/life14040425","article-title":"Unraveling the complexities of oxidative stress and inflammation biomarkers in obstructive sleep apnea syndrome: a comprehensive review","volume":"14","author":"Lavalle","year":"2024","journal-title":"Life"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1513\/AnnalsATS.202309-777OC","article-title":"All obstructive sleep apnea events are not created equal: the relationship between event-related hypoxemia and physiologic response","volume":"21","author":"Hajipour","year":"2024","journal-title":"Ann Am Thorac Soc"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/j.arbres.2025.05.016","article-title":"OSA and accelerated aging: an overarching pathway driving end-organ morbidity and mortality","volume":"61","author":"Badran","year":"2025","journal-title":"Arch Bronconeumol"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1111\/ceo.13834","article-title":"Retinal pigment epithelium and age-related macular degeneration: a review of major disease mechanisms","volume":"48","author":"Somasundaran","year":"2020","journal-title":"Clin Exp Ophthalmol"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1097\/IAE.0000000000004293","article-title":"Incidence and progression of age-related macular degeneration among patients with and without obstructive sleep apnea: a national cohort study","volume":"45","author":"Blazes","year":"2025","journal-title":"Retina"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"3463","DOI":"10.3390\/ijms26083463","article-title":"Role of oxidative stress and inflammation in age related macular degeneration: insights into the retinal pigment epithelium (RPE)","volume":"26","author":"Ochoa Hern\u00e1ndez","year":"2025","journal-title":"Int J Mol Sci"},{"issue":"1","key":"bib10","doi-asserted-by":"publisher","first-page":"P1","DOI":"10.1016\/j.ophtha.2019.09.024","article-title":"Age-related macular degeneration preferred practice pattern","volume":"127","author":"Flaxel","year":"2020","journal-title":"Ophthalmology"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1186\/s12955-017-0751-4","article-title":"Vision-related quality of life and visual outcomes from cataract surgery in patients with vision-threatening diabetic retinopathy: a prospective observational study","volume":"15","author":"Zhu","year":"2017","journal-title":"Health Qual Life Outcomes"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"1609928","DOI":"10.3389\/fcell.2025.1609928","article-title":"Early detection of retinal and choroidal microvascular impairments in diabetic patients with myopia","volume":"13","author":"Wu","year":"2025","journal-title":"Front Cell Dev Biol"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1007\/s40123-023-00697-x","article-title":"Design and validation of a novel smartphone-based visual acuity test: the K-VA test","volume":"12","author":"Karampatakis","year":"2023","journal-title":"Ophthalmol Ther"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"2395","DOI":"10.3390\/diagnostics14212395","article-title":"Validation of inter-reader agreement\/consistency for quantification of ellipsoid zone integrity and sub-RPE compartmental features across retinal diseases","volume":"14","author":"Bell","year":"2024","journal-title":"Diagnostics"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.oret.2022.03.017","article-title":"Correlation between fundus autofluorescence and en face OCT measurements of geographic atrophy","volume":"6","author":"Velaga","year":"2022","journal-title":"Ophthalmol Retina"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1136\/bjophthalmol-2014-305702","article-title":"Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA)","volume":"98","author":"Schmidt-Erfurth","year":"2014","journal-title":"Br J Ophthalmol"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"32","DOI":"10.3390\/metabo12010032","article-title":"Plasma metabolomic profiles associated with three-year progression of age-related macular degeneration","volume":"12","author":"Lains","year":"2022","journal-title":"Metabolites"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/S0895-4356(01)00473-5","article-title":"Predictors of attrition in a longitudinal cognitive aging study: the Maastricht Aging Study (MAAS)","volume":"55","author":"Van Beijsterveldt","year":"2002","journal-title":"J Clin Epidemiol"},{"issue":"3","key":"bib20","doi-asserted-by":"publisher","first-page":"e0120003","DOI":"10.1371\/journal.pone.0120003","article-title":"Association between neovascular age-related macular degeneration and dementia: a population-based case-control study in Taiwan","volume":"10","author":"Chung","year":"2015","journal-title":"PLoS One"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"263","DOI":"10.5664\/jcsm.27497","article-title":"Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults","volume":"5","author":"Medicine AOSATFotAAoS","year":"2009","journal-title":"J Clin Sleep Med"},{"issue":"1","key":"bib22","doi-asserted-by":"publisher","first-page":"e001203","DOI":"10.1136\/bmjophth-2022-001203","article-title":"Role of sleep-disordered breathing in age-related macular degeneration","volume":"8","author":"Fang","year":"2023","journal-title":"BMJ Open Ophthalmol"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"420","DOI":"10.14639\/0392-100X-895","article-title":"Oxidative stress in patients with obstructive sleep apnoea syndrome","volume":"35","author":"Passali","year":"2015","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"3935","DOI":"10.3390\/jcm12123935","article-title":"Evaluation of inflammation and oxidative stress markers in patients with obstructive sleep apnea (OSA)","volume":"12","author":"Pau","year":"2023","journal-title":"J Clin Med"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1038\/s41433-022-02115-1","article-title":"Perspectives from clinical trials: is geographic atrophy one disease?","volume":"37","author":"Sivaprasad","year":"2023","journal-title":"Eye"},{"key":"bib13","first-page":"1061","volume-title":"International consensus statement on obstructive sleep apnea","author":"Chang","year":"2023"}],"container-title":["Investigative Ophthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2811254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:09Z","timestamp":1791927129000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2811254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,18]]},"references-count":25,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2025,12,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.66.15.59","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,18]]}}}