{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:02:06Z","timestamp":1791928926117,"version":"4.3.4"},"reference-count":39,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"2","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2025,2,28]]},"DOI":"10.1167\/iovs.66.2.70","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T10:31:33Z","timestamp":1740738693000},"page":"70","source":"Crossref","is-referenced-by-count":4,"title":["Preferential Locations of Polypoidal Lesions and Adjacent Pigment Epithelium Detachments in Polypoidal Choroidal Vasculopathy in a Japanese Population"],"prefix":"10.1167","volume":"66","author":[{"given":"Takahiro","family":"Kogo","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Muraoka","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaharu","family":"Ishikura","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"Nishigori","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Akiyama","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Ueda-Arakawa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Miyata","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotaro","family":"Ooto","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akitaka","family":"Tsujikawa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"3","key":"bib1","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.ophtha.2020.08.006","article-title":"Polypoidal choroidal vasculopathy: consensus nomenclature and non-indocyanine green angiograph diagnostic criteria from the Asia-Pacific ocular imaging society PCV workgroup","volume":"128","author":"Cheung","year":"2021","journal-title":"Ophthalmology"},{"issue":"6","key":"bib2","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.survophthal.2010.03.004","article-title":"Polypoidal choroidal vasculopathy: a review","volume":"55","author":"Imamura","year":"2010","journal-title":"Surv Ophthalmol"},{"issue":"4","key":"bib3","doi-asserted-by":"publisher","first-page":"162","DOI":"10.3892\/etm.2023.11861","article-title":"Vortex vein engorgement and different shapes of venous drainage systems in polypoid choroidal vasculopathy vs. age-related macular degeneration on indocyanine green angiography","volume":"25","author":"Cai","year":"2023","journal-title":"Exp Ther Med"},{"issue":"4","key":"bib4","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1007\/s00417-022-05905-1","article-title":"Choroidal morphologic features in central serous chorioretinopathy using ultra-widefield optical coherence tomography","volume":"261","author":"Funatsu","year":"2023","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"2","key":"bib5","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1167\/iovs.62.2.29","article-title":"Choroidal vascular abnormalities by ultra-widefield indocyanine green angiography in polypoidal choroidal vasculopathy","volume":"62","author":"Jeong","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib6","doi-asserted-by":"publisher","first-page":"19505","DOI":"10.1038\/s41598-020-75789-w","article-title":"Quantitative measures of vortex veins in the posterior pole in eyes with pachychoroid spectrum diseases","volume":"10","author":"Matsumoto","year":"2020","journal-title":"Sci Rep"},{"issue":"1","key":"bib7","doi-asserted-by":"publisher","first-page":"4492","DOI":"10.1038\/s41598-022-08666-3","article-title":"Clinical characteristics and pachychoroid incidence in Japanese patients with neovascular age-related macular degeneration","volume":"12","author":"Matsumoto","year":"2022","journal-title":"Sci Rep"},{"issue":"12","key":"bib8","doi-asserted-by":"publisher","first-page":"3475","DOI":"10.1007\/s00417-023-06203-0","article-title":"Relationship between pulsation of posterior vortex vein, choroidal thickness, and choroidal vascular hyperpermeability in polypoidal choroidal vasculopathy","volume":"261","author":"Mukai","year":"2023","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"15","key":"bib9","doi-asserted-by":"publisher","first-page":"4614","DOI":"10.3390\/jcm11154614","article-title":"Relationship between pachychoroid and polypoidal choroidal vasculopathy","volume":"11","author":"Yamashiro","year":"2022","journal-title":"J Clin Med"},{"issue":"12","key":"bib10","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1016\/j.oret.2019.06.013","article-title":"Efficacy of photodynamic therapy for polypoidal choroidal vasculopathy associated with and without pachychoroid phenotypes","volume":"3","author":"Hata","year":"2019","journal-title":"Ophthalmol Retina"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.ajo.2021.09.009","article-title":"Clinical factors related to loculation of fluid in central serous chorioretinopathy","volume":"235","author":"Imanaga","year":"2022","journal-title":"Am J Ophthalmol"},{"issue":"9","key":"bib12","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1136\/bjophthalmol-2012-302974","article-title":"Retinal and choroidal changes observed with \u201cen face\u201d enhanced-depth imaging OCT in central serous chorioretinopathy","volume":"97","author":"Lehmann","year":"2013","journal-title":"Br J Ophthalmol"},{"issue":"9","key":"bib13","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/j.oret.2020.03.024","article-title":"Vortex vein anastomosis at the watershed in pachychoroid spectrum diseases","volume":"4","author":"Matsumoto","year":"2020","journal-title":"Ophthalmol Retina"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"100973","DOI":"10.1016\/j.preteyeres.2021.100973","article-title":"Venous overload choroidopathy: a hypothetical framework for central serous chorioretinopathy and allied disorders","volume":"86","author":"Spaide","year":"2022","journal-title":"Prog Retin Eye Res"},{"issue":"4","key":"bib15","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1097\/IAE.0000000000003376","article-title":"Ciliochoroidal effusion in central serous chorioretinopathy","volume":"42","author":"Terao","year":"2022","journal-title":"Retina"},{"issue":"10","key":"bib16","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/j.oret.2022.04.011","article-title":"Widefield choroidal thickness of eyes with central serous chorioretinopathy examined by swept-source OCT","volume":"6","author":"Ishikura","year":"2022","journal-title":"Ophthalmol Retina"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.ajo.2024.01.012","article-title":"Pigment epithelial detachment and leak point locations in central serous chorioretinopathy","volume":"261","author":"Kogo","year":"2024","journal-title":"Am J Ophthalmol"},{"issue":"11","key":"bib18","doi-asserted-by":"publisher","first-page":"3405","DOI":"10.1007\/s00417-022-05687-6","article-title":"A new insight into pachychoroid diseases: remodeling of choroidal vasculature","volume":"260","author":"Kishi","year":"2022","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"1","key":"bib19","doi-asserted-by":"publisher","first-page":"11904","DOI":"10.1038\/s41598-023-38845-9","article-title":"Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography","volume":"13","author":"Hirano","year":"2023","journal-title":"Sci Rep"},{"issue":"1","key":"bib20","doi-asserted-by":"publisher","first-page":"10890","DOI":"10.1038\/s41598-023-37802-w","article-title":"Extensive reduction in choroidal thickness after photodynamic therapy in eyes with central serous chorioretinopathy","volume":"13","author":"Nishigori","year":"2023","journal-title":"Sci Rep"},{"issue":"2","key":"bib21","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.oret.2017.05.013","article-title":"Dilatation of asymmetric vortex vein in central serous chorioretinopathy","volume":"2","author":"Hiroe","year":"2018","journal-title":"Ophthalmol Retina"},{"issue":"11","key":"bib22","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1136\/bjo.59.11.631","article-title":"Segmental nature of the choroidal vasculature","volume":"59","author":"Hayreh","year":"1975","journal-title":"Br J Ophthalmol"},{"issue":"6","key":"bib23","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1007\/BF00175988","article-title":"Improvements on Littmann's method of determining the size of retinal features by fundus photography","volume":"232","author":"Bennett","year":"1994","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"2","key":"bib24","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1097\/IAE.0000000000001541","article-title":"Evaluation of macular ischemia in eyes with branch retinal vein occlusion: an optical coherence tomography angiography study","volume":"38","author":"Kadomoto","year":"2018","journal-title":"Retina"},{"issue":"4","key":"bib25","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1097\/IAE.0000000000001689","article-title":"Disease expression in nonexudative age-related macular degeneration varies with choroidal thickness","volume":"38","author":"Spaide","year":"2018","journal-title":"Retina"},{"issue":"9","key":"bib26","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1016\/j.oret.2020.12.004","article-title":"Clinical and genetic characteristics of pachydrusen in eyes with central serous chorioretinopathy and general Japanese individuals","volume":"5","author":"Takahashi","year":"2021","journal-title":"Ophthalmol Retina"},{"issue":"1","key":"bib27","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.survophthal.2003.10.007","article-title":"Polypoidal choroidal vasculopathy","volume":"49","author":"Ciardella","year":"2004","journal-title":"Surv Ophthalmol"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.ajo.2023.12.013","article-title":"En face optical coherence tomography illustrates the trizonal distribution of drusen and subretinal drusenoid deposits in the macula","volume":"261","author":"Voichanski","year":"2024","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"bib29","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.ajo.2007.03.047","article-title":"Clinical characteristics of exudative age-related macular degeneration in Japanese patients","volume":"144","author":"Maruko","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"12","key":"bib30","doi-asserted-by":"publisher","first-page":"1748","DOI":"10.1136\/bjophthalmol-2021-319403","article-title":"Incidence of central serous chorioretinopathy (2011\u20132018): a nationwide population-based cohort study of Japan","volume":"106","author":"Kido","year":"2022","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"bib31","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1097\/IAE.0b013e31826af540","article-title":"Engorgement of vortex vein and polypoidal choroidal vasculopathy","volume":"33","author":"Chung","year":"2013","journal-title":"Retina"},{"issue":"8","key":"bib32","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1007\/s00417-011-1620-1","article-title":"Subfoveal choroidal thickness in typical age-related macular degeneration and polypoidal choroidal vasculopathy","volume":"249","author":"Koizumi","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"9","key":"bib33","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1016\/j.ophtha.2022.04.018","article-title":"Genome-wide survival analysis for macular neovascularization development in central serous chorioretinopathy revealed shared genetic susceptibility with polypoidal choroidal vasculopathy","volume":"129","author":"Mori","year":"2022","journal-title":"Ophthalmology"},{"issue":"8","key":"bib34","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1097\/IAE.0000000000002188","article-title":"Choroidal morphology in eyes with peripapillary polypoidal choroidal vasculopathy","volume":"39","author":"Baek","year":"2019","journal-title":"Retina"},{"issue":"7","key":"bib35","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1007\/s00417-010-1575-7","article-title":"Clinical characteristics of polypoidal choroidal vasculopathy in Chinese patients","volume":"249","author":"Hou","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"8","key":"bib36","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1136\/bjo.86.8.892","article-title":"Polypoidal choroidal vasculopathy in Chinese patients","volume":"86","author":"Kwok","year":"2002","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"bib37","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1097\/00006982-199515020-00003","article-title":"Indocyanine green videoangiography of idiopathic polypoidal choroidal vasculopathy","volume":"15","author":"Spaide","year":"1995","journal-title":"Retina"},{"issue":"8","key":"bib38","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s00417-003-0667-z","article-title":"Polypoidal choroidal vasculopathy in elderly Chinese patients","volume":"242","author":"Wen","year":"2004","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"4","key":"bib39","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1001\/archopht.1997.01100150480005","article-title":"The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy","volume":"115","author":"Yannuzzi","year":"1997","journal-title":"Arch Ophthalmol"}],"container-title":["Investigative Ophthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2802643","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:11Z","timestamp":1791927131000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2802643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,28]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,3]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.66.2.70","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,28]]}}}