{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:01:56Z","timestamp":1791928916009,"version":"4.3.4"},"reference-count":38,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"3","license":[{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2025,3,21]]},"DOI":"10.1167\/iovs.66.3.47","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T11:36:06Z","timestamp":1742556966000},"page":"47","source":"Crossref","is-referenced-by-count":0,"title":["Effects of a Hyperbaric Normoxic Environment on the Retina and Choroid"],"prefix":"10.1167","volume":"66","author":[{"given":"Nur","family":"Demir","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Sultan 2. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey"},{"name":"https:\/\/orcid.org\/0000-0003-0738-7212"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belma","family":"Kayhan","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Sultan 2. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey"},{"name":"https:\/\/orcid.org\/0000-0003-0748-6691"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yavuz","family":"Aslan","sequence":"additional","affiliation":[{"name":"Undersea and Hyperbaric Medicine Department, Sultan 2. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey"},{"name":"https:\/\/orcid.org\/0000-0003-3032-683X"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"3","key":"bib1","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.surneu.2006.06.060","article-title":"The influence of barometric pressure changes and standard meteorological variables on the occurrence and clinical features of subarachnoid hemorrhage","volume":"67","author":"Setzer","year":"2007","journal-title":"Surg Neurol"},{"key":"bib2","first-page":"597106","article-title":"Meteorological variables associated with stroke","volume":"2014","author":"Nocera","year":"2014","journal-title":"Int Sch Res Notices"},{"issue":"4","key":"bib3","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3109\/10641963.2010.491886","article-title":"Inverse correlation between seasonal changes in home blood pressure and atmospheric temperature in treated-hypertensive patients","volume":"32","author":"Iwabu","year":"2010","journal-title":"Clin Exp Hypertens"},{"issue":"1","key":"bib4","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1161\/01.CIR.100.1.e1","article-title":"Unhealthy effects of atmospheric temperature and pressure on the occurrence of myocardial infarction and coronary deaths. A 10-year survey: The Lille-World Health Organization MONICA project (Monitoring trends and determinants in cardiovascular disease)","volume":"100","author":"Danet","year":"1999","journal-title":"Circulation"},{"issue":"3","key":"bib5","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/15569527.2022.2094941","article-title":"The effect of hyperbaric oxygen therapy on central macular thickness and choroidal thickness in the healthy eyes of patients with idiopathic sudden sensorineural hearing loss","volume":"41","author":"D\u00f6nmez G\u00fcn","year":"2022","journal-title":"Cutan Ocul Toxicol"},{"issue":"3","key":"bib6","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/00006324-197503000-00002","article-title":"Effects of hyperbaric air pressure on keratometry","volume":"52","author":"Welsh","year":"1975","journal-title":"Am J Optom Physiol Opt"},{"issue":"12","key":"bib7","doi-asserted-by":"crossref","first-page":"5392","DOI":"10.1167\/iovs.07-1578","article-title":"Influences of atmospheric pressure and temperature on intraocular pressure","volume":"49","author":"Van de Veire","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"bib8","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0039-6257(05)80091-8","article-title":"Diving and hyperbaric ophthalmology","volume":"39","author":"Butler","year":"1995","journal-title":"Surv Ophthalmol"},{"issue":"2","key":"bib9","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1152\/japplphysiol.00569.2021","article-title":"Blood gas analyses in hyperbaric and underwater environments: A systematic review","volume":"132","author":"Paganini","year":"2022","journal-title":"J Appl Physiol (1985)"},{"issue":"1","key":"bib10","doi-asserted-by":"crossref","first-page":"30","DOI":"10.4103\/2045-9912.310057","article-title":"Therapeutic effects of hyperbaric oxygen: Integrated review","volume":"11","author":"Sen","year":"2021","journal-title":"Med Gas Res"},{"issue":"10","key":"bib11","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1097\/IAE.0000000000002931","article-title":"Choroidal blood flow: Review and potential explanation for the choroidal venous anatomy including the vortex vein system","volume":"40","author":"Spaide","year":"2020","journal-title":"Retina"},{"issue":"1","key":"bib12","first-page":"47","article-title":"Laser Doppler velocimetry study of the effect of pure oxygen breathing on retinal blood flow","volume":"24","author":"Riva","year":"1983","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"bib13","first-page":"2906","article-title":"Effects of oxygen and carbogen breathing on choroidal hemodynamics in humans","volume":"40","author":"Kergoat","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib14","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1152\/jappl.1993.75.2.581","article-title":"Central cardiovascular pressures during graded water immersion in humans","volume":"75","author":"Gabrielsen","year":"1993","journal-title":"J Appl Physiol (1985)"},{"issue":"1","key":"bib15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12987-017-0065-2","article-title":"Human jugular vein collapse in the upright posture: implications for postural intracranial pressure regulation","volume":"14","author":"Holmlund","year":"2017","journal-title":"Fluids Barriers CNS"},{"issue":"3","key":"bib16","first-page":"181","article-title":"The effect of head-down tilt and water immersion on intracranial pressure in nonhuman primates","volume":"63","author":"Keil","year":"1992","journal-title":"Aviat Space Environ Med"},{"issue":"2","key":"bib17","first-page":"135","article-title":"Nitric oxide-related endothelial changes in breath-hold and scuba divers","volume":"40","author":"Theunissen","year":"2013","journal-title":"Undersea Hyperb Med"},{"issue":"1","key":"bib18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s00062-008-8006-8","article-title":"Long-term neurologic damage and brain lesions in recreational divers","volume":"18","author":"Knauth","year":"2008","journal-title":"Clin Neuroradiol Klin Neuroradiol"},{"issue":"7096","key":"bib19","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1136\/bmj.314.7096.1761","article-title":"Brain damage in divers. The risk has been underestimated","volume":"314","author":"Yates","year":"1997","journal-title":"BMJ"},{"issue":"1","key":"bib20","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1161\/01.STR.29.1.94","article-title":"Effects of high atmospheric pressure and oxygen on middle cerebral blood flow velocity in humans measured by transcranial Doppler","volume":"29","author":"Omae","year":"1998","journal-title":"Stroke"},{"issue":"9","key":"bib21","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1113\/EP088746","article-title":"Alterations in resting cerebrovascular regulation do not affect reactivity to hypoxia, hyperoxia or neurovascular coupling following a SCUBA dive","volume":"105","author":"Caldwell","year":"2020","journal-title":"Exp Physiol"},{"issue":"6","key":"bib23","first-page":"508","article-title":"Intracranial venous hypertension and venous sinus stenting in the modern management of idiopathic intracranial hypertension","volume":"11","author":"Townsend","year":"2021","journal-title":"Life (Basel)"},{"issue":"1","key":"bib24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/ICB.0000000000000090","article-title":"Multifocal central serous chorioretinopathy with photoreceptor-retinal pigment epithelium diastasis in heritable pulmonary arterial hypertension","volume":"9","author":"Li","year":"2015","journal-title":"Retin Cases Brief Rep"},{"issue":"15","key":"bib25","first-page":"4364","article-title":"Changes of choroidal thickness as measured with spectral domain OCT in patients with idiopathic intracranial hypertension after lowering of intracranial pressure","volume":"54","author":"Pemp","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib26","doi-asserted-by":"crossref","first-page":"636","DOI":"10.4103\/0028-3886.288980","article-title":"Measurement of choroid thickness using optical coherence tomography to monitor intracranial pressure in an idiopathic cranial hypertension model","volume":"68","author":"Ozdemir","year":"2020","journal-title":"Neurol India"},{"issue":"1","key":"bib27","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00484-016-1202-3","article-title":"The major influence of the atmosphere on intracranial pressure: An observational study","volume":"61","author":"Herbowski","year":"2017","journal-title":"Int J Biometeorol"},{"key":"bib28","first-page":"89","article-title":"Effect of scuba-diving on optic nerve and sheath diameters","volume":"28","author":"Mehrpour","year":"2014","journal-title":"Med J Islam Repub Iran"},{"issue":"3","key":"bib29","first-page":"393","article-title":"Change in the foveal avascular zone and macular capillary network density after hyperbaric oxygen therapy in healthy retina","volume":"16","author":"\u00c7evik","year":"2021","journal-title":"J Ophthalmic Vis Res"},{"key":"bib30","doi-asserted-by":"crossref","first-page":"1600148","DOI":"10.1155\/2024\/1600148","article-title":"Retinal layer and choroidal changes in deep and scuba divers: Evidence of pachychoroid spectrum-like findings","volume":"2024","author":"Demir","year":"2024","journal-title":"J Ophthalmol"},{"issue":"3","key":"bib31","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1113\/JP271182","article-title":"Relationship between retinal blood flow and arterial oxygen","volume":"594","author":"Cheng","year":"2016","journal-title":"J Physiol"},{"issue":"2","key":"bib32","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1167\/iovs.64.2.9","article-title":"Variability of vascular reactivity in the retina and choriocapillaris to oxygen and carbon dioxide using optical coherence tomography angiography","volume":"64","author":"Ashimatey","year":"2023","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"bib33","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1167\/iovs.61.10.3","article-title":"Three-dimensional characterization of the normal human parafoveal microvasculature using structural criteria and high-resolution confocal microscopy","volume":"61","author":"An","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib34","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1186\/s12886-022-02673-8","article-title":"Superficial capillary plexus vessel density\/deep capillary plexus vessel density ratio in healthy eyes","volume":"22","author":"Nam","year":"2022","journal-title":"BMC Ophthalmol"},{"issue":"2","key":"bib35","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ophtha.2007.04.052","article-title":"Three-dimensional imaging of cystoid macular edema in retinal vein occlusion","volume":"115","author":"Yamaike","year":"2008","journal-title":"Ophthalmology"},{"issue":"5","key":"bib36","doi-asserted-by":"crossref","first-page":"e0268770","DOI":"10.1371\/journal.pone.0268770","article-title":"The assessment of acute chorioretinal changes due to intensive physical exercise in young adults","volume":"17","author":"Szalai","year":"2022","journal-title":"PLoS One"},{"issue":"4","key":"bib37","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/00061198-199608000-00008","article-title":"Laser Doppler flowmetry measurement of changes in human optic nerve head blood flow in response to blood gas perturbations","volume":"5","author":"Harris","year":"1996","journal-title":"J Glaucoma"},{"issue":"10","key":"bib38","doi-asserted-by":"crossref","first-page":"4464","DOI":"10.1167\/iovs.16-19603","article-title":"Microcirculatory responses to hyperoxia in macular and peripapillary regions","volume":"57","author":"Xu","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib22","article-title":"Anatomy, head and neck: Eye ophthalmic vein","volume-title":"StatPearls","author":"Azzam","year":"2023"}],"container-title":["Investigative Ophthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2802717","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:06Z","timestamp":1791927126000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2802717"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,21]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3,3]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.66.3.47","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,21]]}}}