{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:01:27Z","timestamp":1791928887480,"version":"4.3.4"},"reference-count":42,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"6","license":[{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"DOI":"10.1167\/iovs.66.6.64","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T08:30:29Z","timestamp":1750667429000},"page":"64","source":"Crossref","is-referenced-by-count":3,"title":["Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes"],"prefix":"10.1167","volume":"66","author":[{"given":"Abraham","family":"Hang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Vision Science, University of California Davis Eye Center, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Vision Science, University of California Davis Eye Center, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Shea","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Vision Science, University of California Davis Eye Center, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel J.","family":"Roux","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Strasbourg, CNRS (UMR 7104), Inserm (UMR-S 1258), Illkirch, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise M.","family":"Imai-Leonard","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California Davis, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Adams","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanori","family":"Amano","sequence":"additional","affiliation":[{"name":"RIKEN BioResource Research Center, Tsukuba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oana V.","family":"Amarie","sequence":"additional","affiliation":[{"name":"Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum Mu\u0308nchen, Neuherberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zorana","family":"Berberovic","sequence":"additional","affiliation":[{"name":"The Centre for Phenogenomics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rapha\u00ebl","family":"Bour","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN-Institut Clinique de la Souris (ICS), Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynette","family":"Bower","sequence":"additional","affiliation":[{"name":"Mouse Biology Program, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian C.","family":"Leonard","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve D.","family":"Brown","sequence":"additional","affiliation":[{"name":"Medical Research Council, Harwell Institute, Harwell, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo Young","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Molecular and Life Science, Hanyang University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Clementson-Mobbs","sequence":"additional","affiliation":[{"name":"Mary Lyon Centre, Medical Research Council, Harwell Institute, Harwell, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail J.","family":"D'Souza","sequence":"additional","affiliation":[{"name":"The Centre for Phenogenomics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Dickinson","sequence":"additional","affiliation":[{"name":"Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Eskandarian","sequence":"additional","affiliation":[{"name":"The Centre for Phenogenomics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann M.","family":"Flenniken","sequence":"additional","affiliation":[{"name":"The Centre for Phenogenomics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum Mu\u0308nchen, Neuherberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Gailus-Durner","sequence":"additional","affiliation":[{"name":"Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum Mu\u0308nchen, Neuherberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Heaney","sequence":"additional","affiliation":[{"name":"Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"H\u00e9rault","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN-Institut Clinique de la Souris (ICS), Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Hrabe de Angelis","sequence":"additional","affiliation":[{"name":"Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum Mu\u0308nchen, Neuherberg, Germany"},{"name":"Chair of Experimental Genetics, TUM School of Life Sciences, Technische Universit\u00e4t M\u00fcnchen, Freising, Germany"},{"name":"German Center for Diabetes Research (DZD), Neuherberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Wei","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shundan","family":"Jin","sequence":"additional","affiliation":[{"name":"RIKEN BioResource Research Center, Tsukuba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"Joynson","sequence":"additional","affiliation":[{"name":"Mary Lyon Centre, Medical Research Council, Harwell Institute, Harwell, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeon Kyung","family":"Kang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haerim","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory Animal Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Masuya","sequence":"additional","affiliation":[{"name":"RIKEN BioResource Research Center, Tsukuba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki-Hoan","family":"Nam","sequence":"additional","affiliation":[{"name":"Laboratory Animal Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyuna","family":"Noh","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauryl M. J.","family":"Nutter","sequence":"additional","affiliation":[{"name":"The Centre for Phenogenomics, The Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Palkova","sequence":"additional","affiliation":[{"name":"Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Prochazka","sequence":"additional","affiliation":[{"name":"Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miles Joseph","family":"Raishbrook","sequence":"additional","affiliation":[{"name":"Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Riet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN-Institut Clinique de la Souris (ICS), Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Salazar","sequence":"additional","affiliation":[{"name":"Mouse Biology Program, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Richard","family":"Seavitt","sequence":"additional","affiliation":[{"name":"Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radislav","family":"Sedlacek","sequence":"additional","affiliation":[{"name":"Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Selloum","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN-Institut Clinique de la Souris (ICS), Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung Yul","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Je Kyung","family":"Seong","sequence":"additional","affiliation":[{"name":"Laboratory of Developmental Biology and Genomics, Research Institute of Veterinary Science, BK21 Plus Program for Advanced Veterinary Science, College of Veterinary Medicine and Interdisciplinary Program for Bioinformatics, Seoul National University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae-Sol","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Shiroishi","sequence":"additional","affiliation":[{"name":"RIKEN BioResource Research Center, Tsukuba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Sorg","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN-Institut Clinique de la Souris (ICS), Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Stewart","sequence":"additional","affiliation":[{"name":"Mary Lyon Centre, Medical Research Council, Harwell Institute, Harwell, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Tamura","sequence":"additional","affiliation":[{"name":"RIKEN BioResource Research Center, Tsukuba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Tolentino","sequence":"additional","affiliation":[{"name":"Mouse Biology Program, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uchechukwu","family":"Udensi","sequence":"additional","affiliation":[{"name":"Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Wells","sequence":"additional","affiliation":[{"name":"Mary Lyon Centre, Medical Research Council, Harwell Institute, Harwell, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Wurst","sequence":"additional","affiliation":[{"name":"Institute of Developmental Genetics, Helmholtz Munich, Neuherberg, Germany"},{"name":"Developmental Genetics, Munich School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany"},{"name":"Munich Cluster of Systems Neurology (SyNergy), Munich, Germany"},{"name":"German Center for Neurodegenerative Diseases (DZNE), Munich, Germany"},{"name":"German Center for Mental Health (DZPG), Munich-Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Yoshiki","sequence":"additional","affiliation":[{"name":"RIKEN BioResource Research Center, Tsukuba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Meziane","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Strasbourg, CNRS, INSERM, CELPHEDIA, PHENOMIN-Institut Clinique de la Souris (ICS), Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn","family":"Yiu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Vision Science, University of California Davis Eye Center, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Sieving","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Vision Science, University of California Davis Eye Center, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Lanoue","sequence":"additional","affiliation":[{"name":"Mouse Biology Program, University of California Davis, Davis, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K C. Kent","family":"Lloyd","sequence":"additional","affiliation":[{"name":"Mouse Biology Program, University of California Davis, Davis, California, United States"},{"name":"Department of Surgery, School of Medicine, University of California Davis, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"McKerlie","sequence":"additional","affiliation":[{"name":"The Centre for Phenogenomics, The Hospital for Sick Children, Toronto, Ontario, Canada"},{"name":"Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ala","family":"Moshiri","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Vision Science, University of California Davis Eye Center, Sacramento, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the International Mouse Phenotyping Consortium (IMPC)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","published-online":{"date-parts":[[2025,6,23]]},"reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S0959-437X(00)00195-7","article-title":"Molecular genetics and prospects for therapy of the inherited retinal dystrophies","volume":"11","author":"Bessant","year":"2001","journal-title":"Curr Opin Genet Dev"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.preteyeres.2010.03.004","article-title":"The molecular basis of human retinal and vitreoretinal diseases","volume":"29","author":"Berger","year":"2010","journal-title":"Prog Retin Eye Res"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1016\/j.ophtha.2020.04.008","article-title":"Genetic basis of inherited retinal disease in a molecularly characterized cohort of more Than 3000 families from the United Kingdom","volume":"127","author":"Pontikos","year":"2020","journal-title":"Ophthalmology"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1002\/ajmg.c.31843","article-title":"Genetic testing for inherited eye conditions in over 6,000 individuals through the eyeGENE network","volume":"184","author":"Goetz","year":"2020","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1016\/j.oret.2022.03.011","article-title":"The current state of genetic testing platforms for inherited retinal diseases","volume":"6","author":"Mustafi","year":"2022","journal-title":"Ophthalmol Retina"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"e0145951","DOI":"10.1371\/journal.pone.0145951","article-title":"Mutation detection in patients with retinal dystrophies using targeted next generation sequencing","volume":"11","author":"Weisschuh","year":"2016","journal-title":"PLoS One"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1002\/humu.24064","article-title":"Genetic architecture of inherited retinal degeneration in Germany: a large cohort study from a single diagnostic center over a 9-year period","volume":"41","author":"Weisschuh","year":"2020","journal-title":"Hum Mutat"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1007\/s00335-015-9599-2","article-title":"A mouse informatics platform for phenotypic and translational discovery","volume":"26","author":"Ring","year":"2015","journal-title":"Mamm Genome"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"D1038","DOI":"10.1093\/nar\/gkac972","article-title":"The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease","volume":"51","author":"Groza","year":"2023","journal-title":"Nucleic Acids Res"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"e1002151","DOI":"10.1371\/journal.pbio.1002151","article-title":"Applying the ARRIVE guidelines to an in vivo database","volume":"13","author":"Karp","year":"2015","journal-title":"PLoS Biol"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"giab061","DOI":"10.1093\/gigascience\/giab061","article-title":"Building the mega single-cell transcriptome ocular meta-atlas","volume":"10","author":"Swamy","year":"2021","journal-title":"GigaScience"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1038\/s42003-018-0226-0","article-title":"Identification of genes required for eye development by high-throughput screening of mouse knockouts","volume":"1","author":"Moore","year":"2018","journal-title":"Commun Biol"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"2921","DOI":"10.1167\/iovs.12-9662","article-title":"The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL\/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes","volume":"53","author":"Mattapallil","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"2252","DOI":"10.1167\/iovs.17-23513","article-title":"A population study of common ocular abnormalities in C57BL\/6N rd8 mice","volume":"59","author":"Moore","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"2689","DOI":"10.1007\/s00417-013-2373-9","article-title":"Vitreous fluid and circulating levels of soluble lr11, a novel marker for progression of diabetic retinopathy","volume":"251","author":"Shiba","year":"2013","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1080\/13816810.2017.1288825","article-title":"Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration","volume":"38","author":"Garc\u00eda","year":"2017","journal-title":"Ophthalmic Genet"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"16728","DOI":"10.1038\/s41598-018-34955-x","article-title":"Proteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina","volume":"8","author":"Saddala","year":"2018","journal-title":"Sci Rep"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"3106","DOI":"10.1007\/s12035-020-01946-x","article-title":"SORLA expression in synaptic plexiform layers of mouse retina","volume":"57","author":"Monti","year":"2020","journal-title":"Mol Neurobiol"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1111\/j.1471-4159.1988.tb02477.x","article-title":"Alterations in retinal tyrosine and dopamine levels in rats consuming protein or tyrosine-supplemented diets","volume":"50","author":"Gibson","year":"1988","journal-title":"J Neurochem"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"4230","DOI":"10.3390\/ijms23084230","article-title":"Heterozygous and homozygous variants in SORL1 gene in Alzheimer's disease patients: clinical, neuroimaging and neuropathological findings","volume":"23","author":"Alvarez-Mora","year":"2022","journal-title":"Int J Mol Sci"},{"key":"bib21","first-page":"3","article-title":"[P4-ATP-ase Atp8b1\/FIC1: structural properties and (patho)physiological functions]","volume":"41","author":"Korneenko","year":"2015","journal-title":"Bioorg Khim"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"e11306","DOI":"10.7554\/eLife.11306","article-title":"ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization","volume":"4","author":"Lin","year":"2015","journal-title":"eLife"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1080\/15548627.2021.1940610","article-title":"The soluble reticulophagy receptor CALCOCO1 is also a Golgiphagy receptor","volume":"17","author":"Nthiga","year":"2021","journal-title":"Autophagy"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"2107","DOI":"10.1038\/s41418-022-01002-2","article-title":"Trim39 regulates neuronal apoptosis by acting as a SUMO-targeted E3 ubiquitin-ligase for the transcription factor NFATc3","volume":"29","author":"Basu-Shrivastava","year":"2022","journal-title":"Cell Death Differ"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"631","DOI":"10.3892\/mmr.2012.964","article-title":"Single-nucleotide polymorphisms in the TSPYL-4 and NT5DC1 genes are associated with susceptibility to chronic obstructive pulmonary disease","volume":"6","author":"Guo","year":"2012","journal-title":"Mol Med Rep"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"3117","DOI":"10.1007\/s12033-023-00934-5","article-title":"THSD7A as a promising biomarker for membranous nephrosis","volume":"66","author":"Jiang","year":"2024","journal-title":"Mol Biotechnol"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"e7456","DOI":"10.7717\/peerj.7456","article-title":"lncRNA TMEM51-AS1 and RUSC1-AS1 function as ceRNAs for induction of laryngeal squamous cell carcinoma and prediction of prognosis","volume":"7","author":"Hui","year":"2019","journal-title":"PeerJ"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"101029","DOI":"10.1016\/j.preteyeres.2021.101029","article-title":"Inherited retinal diseases: linking genes, disease-causing variants, and relevant therapeutic modalities","volume":"89","author":"Schneider","year":"2022","journal-title":"Prog Retin Eye Res"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"2710","DOI":"10.1073\/pnas.1913179117","article-title":"Worldwide carrier frequency and genetic prevalence of autosomal recessive inherited retinal diseases","volume":"117","author":"Hanany","year":"2020","journal-title":"Proc Natl Acad Sci USA"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1093\/hmg\/11.10.1219","article-title":"Retinitis pigmentosa and allied diseases: numerous diseases, genes, and inheritance patterns","volume":"11","author":"Rivolta","year":"2002","journal-title":"Hum Mol Genet"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"794805","DOI":"10.3389\/fgene.2021.794805","article-title":"Gene-based therapeutics for inherited retinal diseases","volume":"12","author":"Fenner","year":"2021","journal-title":"Front Genet"},{"key":"bib32","first-page":"e29583","article-title":"Age-related macular degeneration: epidemiology, pathophysiology, diagnosis, and treatment","volume":"14","author":"Vyawahare","year":"2022","journal-title":"Cureus"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s12041-009-0064-4","article-title":"The molecular genetic basis of age-related macular degeneration: an overview","volume":"88","author":"Katta","year":"2009","journal-title":"J Genet"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1016\/S0002-9440(10)64427-6","article-title":"Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model","volume":"161","author":"Rakoczy","year":"2002","journal-title":"Am J Pathol"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1167\/iovs.05-0719","article-title":"Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD","volume":"47","author":"Espinosa-Heidmann","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"16651","DOI":"10.1073\/pnas.0705079104","article-title":"Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction","volume":"104","author":"Coffey","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"2423","DOI":"10.1093\/hmg\/ddm199","article-title":"Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: a model for the early pathogenic course of macular degeneration","volume":"16","author":"Marmorstein","year":"2007","journal-title":"Hum Mol Genet"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"e0125631","DOI":"10.1371\/journal.pone.0125631","article-title":"A comparison of some organizational characteristics of the mouse central retina and the human macula","volume":"10","author":"Volland","year":"2015","journal-title":"PLoS One"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"12574","DOI":"10.1038\/s41598-019-49121-0","article-title":"Fundamental differences in patterns of retinal ageing between primates and mice","volume":"9","author":"Kam","year":"2019","journal-title":"Sci Rep"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"2594","DOI":"10.3390\/cells9122594","article-title":"The role of adrenoceptors in the retina","volume":"9","author":"Ruan","year":"2020","journal-title":"Cells"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1023\/B:DOOP.0000019487.88486.0a","article-title":"Dopamine and retinal function","volume":"108","author":"Witkovsky","year":"2004","journal-title":"Doc Ophthalmol"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1002\/cne.20902","article-title":"Histamine receptors in mammalian retinas","volume":"495","author":"Gastinger","year":"2006","journal-title":"J Comp Neurol"}],"container-title":["Investigative Ophthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2803168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:10Z","timestamp":1791927130000},"score":1,"resource":{"primary":{"URL":"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2803168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,23]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6,2]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.66.6.64","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,23]]}}}