{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:02:35Z","timestamp":1791928955878,"version":"4.3.4"},"reference-count":29,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"10","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2026,8,6]]},"DOI":"10.1167\/iovs.67.10.17","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T12:30:40Z","timestamp":1786019440000},"page":"17","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal Assessment of Low Luminance Questionnaire Scores in Early and Intermediate AMD"],"prefix":"10.1167","volume":"67","author":[{"given":"Richmond","family":"Woodward","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Duke University, Durham, North Carolina, United States"},{"name":"Retina Service, Massachusetts Eye and Ear, Boston, Massachusetts, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pali","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Duke University, Durham, North Carolina, United States"},{"name":"University of Virginia Health System, Charlottesville, Virginia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Stinnett","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Duke University, Durham, North Carolina, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich F. O.","family":"Luhmann","sequence":"additional","affiliation":[{"name":"Roche Pharmaceutical Research and Early Development, Translational Medicine Ophthalmology, Roche Innovation Center, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunay","family":"Uludag Kirimli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Duke University, Durham, North Carolina, United States"},{"name":"Byers Eye Institute, Stanford University, Palo Alto, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora M.","family":"Lad","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Duke University, Durham, North Carolina, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"4","key":"bib1","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1001\/archophthalmol.2009.58","article-title":"Forecasting age-related macular degeneration through the year 2050: the potential impact of new treatments","volume":"127","author":"Rein","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"2","key":"bib2","doi-asserted-by":"publisher","first-page":"e106","DOI":"10.1016\/S2214-109X(13)70145-1","article-title":"Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis","volume":"2","author":"Wong","year":"2014","journal-title":"Lancet Glob Health"},{"issue":"4","key":"bib3","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.ophtha.2012.10.036","article-title":"Clinical classification of age-related macular degeneration","volume":"120","author":"Ferris","year":"2013","journal-title":"Ophthalmology"},{"issue":"5a Suppl","key":"bib4","first-page":"S2","article-title":"Geographic atrophy: mechanism of disease, pathophysiology, and role of the complement system","volume":"29","author":"Bakri","year":"2023","journal-title":"J Manag Care Spec Pharm"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"1411278","DOI":"10.3389\/fmed.2024.1411278","article-title":"Treatment of neovascular age-related macular degeneration with anti-vascular endothelial growth factor drugs: progress from mechanisms to clinical applications","volume":"11","author":"Cheng","year":"2024","journal-title":"Front. Med"},{"issue":"8","key":"bib6","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1097\/OPX.0000000000000003","article-title":"National Eye Institute Visual Function Questionnaire: usefulness in glaucoma","volume":"90","author":"Nassiri","year":"2013","journal-title":"Optom Vis Sci"},{"issue":"4","key":"bib7","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1001\/jamaophthalmol.2014.5963","article-title":"Longitudinal changes in microperimetry and low luminance visual acuity in age-related macular degeneration","volume":"133","author":"Wu","year":"2015","journal-title":"JAMA Ophthalmol"},{"issue":"4","key":"bib8","doi-asserted-by":"publisher","first-page":"AMD202","DOI":"10.1167\/iovs.18-24227","article-title":"Slowed dark adaptation in early AMD: dual stimulus reveals scotopic and photopic abnormalities","volume":"59","author":"Tahir","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib9","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1167\/iovs.05-1222","article-title":"Development of a questionnaire to assess vision problems under low luminance in age-related maculopathy","volume":"47","author":"Owsley","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib10","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1167\/iovs.17-22528","article-title":"Association of Low Luminance Questionnaire with objective functional measures in early and intermediate age-related macular degeneration","volume":"59","author":"Thompson","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"bib11","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1016\/j.ophtha.2017.05.005","article-title":"Decreased visual function scores on a Low Luminance Questionnaire is associated with impaired dark adaptation","volume":"124","author":"Yazdanie","year":"2017","journal-title":"Ophthalmology"},{"issue":"3","key":"bib12","doi-asserted-by":"publisher","first-page":"100173","DOI":"10.1016\/j.xops.2022.100173","article-title":"Longitudinal evaluation of visual function impairments in early and intermediate age-related macular degeneration patients","volume":"2","author":"Lad","year":"2022","journal-title":"Ophthalmol Sci"},{"key":"bib13","first-page":"1417e1436","article-title":"A randomized, placebo controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8","volume":"119","author":"Kassoff","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ajo.2018.02.012","article-title":"Visual function metrics in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints","volume":"189","author":"Cocce","year":"2018","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"bib15","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.jclinepi.2006.03.012","article-title":"Quality criteria were proposed for measurement properties of health status questionnaires","volume":"60","author":"Terwee","year":"2007","journal-title":"J Clin Epidemiol"},{"issue":"4","key":"bib16","doi-asserted-by":"publisher","first-page":"e0015","DOI":"10.2106\/JBJS.OA.19.00015","article-title":"Floor and ceiling effects, time to completion, and question burden of PROMIS CAT domains among shoulder and knee patients undergoing nonoperative and operative treatment","volume":"4","author":"Gulledge","year":"2019","journal-title":"JB JS Open Access"},{"issue":"7","key":"bib17","doi-asserted-by":"publisher","first-page":"e007765","DOI":"10.1136\/bmjopen-2015-007765","article-title":"Floor and ceiling effects in the OHS: an analysis of the NHS PROMs data set","volume":"5","author":"Lim","year":"2015","journal-title":"BMJ Open"},{"issue":"6","key":"bib18","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1016\/j.ophtha.2018.09.039","article-title":"Longitudinal study of dark adaptation as a functional outcome measure for age-related macular degeneration","volume":"126","author":"Chen","year":"2019","journal-title":"Ophthalmology"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s12886-016-0274-5","article-title":"Vision-targeted health related quality of life in older adults: patient-reported visibility problems in low luminance activities are more likely to decline than daytime activities","volume":"16","author":"Owsley","year":"2016","journal-title":"BMC Ophthalmol"},{"key":"bib20","first-page":"1236","article-title":"Photoreceptor loss in age- related macular degeneration","volume":"37","author":"Curcio","year":"1996","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib22","first-page":"267","article-title":"Psychophysical evidence for rod vulnerability in age-related macular degeneration","volume":"41","author":"Owsley","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7","key":"bib23","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1016\/S0161-6420(01)00580-2","article-title":"Delays in rod-mediated dark adaptation in early age-related maculopathy","volume":"108","author":"Owsley","year":"2001","journal-title":"Ophthalmology"},{"issue":"11","key":"bib24","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1016\/j.ophtha.2025.06.013","article-title":"Delayed rod-mediated dark adaptation is associated with incidence and early progression of age-related macular degeneration","volume":"132","author":"Owsley","year":"2025","journal-title":"Ophthalmology"},{"issue":"2","key":"bib25","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000491402","article-title":"MACUSTAR: development and clinical validation of functional, structural, and patient-reported endpoints in intermediate age-related macular degeneration","volume":"241","author":"Finger","year":"2019","journal-title":"Ophthalmologica"},{"issue":"8","key":"bib26","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1136\/bjophthalmol-2021-320848","article-title":"Disease-specific assessment of Vision Impairment in Low Luminance in age-related macular degeneration - a MACUSTAR study report","volume":"107","author":"Terheyden","year":"2023","journal-title":"Br J Ophthalmol"},{"issue":"5","key":"bib27","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1016\/j.jval.2024.02.001","article-title":"Development and valuation of a preference-weighted measure in age-related macular degeneration from the vision impairment in Low Luminance Questionnaire: a MACUSTAR report","volume":"27","author":"Rowen","year":"2024","journal-title":"Value Health"},{"issue":"4","key":"bib29","doi-asserted-by":"publisher","first-page":"100708","DOI":"10.1016\/j.xops.2025.100708","article-title":"Heterogeneous visual function deficits in intermediate age-related macular degeneration: A MACUSTAR report.","volume":"5","author":"Dunbar","year":"2025","journal-title":"Ophthalmol Sci."},{"key":"bib21","first-page":"45","article-title":"Photoreceptor degeneration in aging and age-related maculopathy","volume-title":"Macular degeneration: science and medicine in practice","author":"Jackson","year":"2004"},{"key":"bib28","doi-asserted-by":"crossref","DOI":"10.4324\/9781315814698","volume-title":"Applying the Rasch model: fundamental measurement in the human sciences","author":"Bond","year":"2015","edition":"3rd ed."}],"container-title":["Investigative Ophthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.67.10.17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:15Z","timestamp":1791927135000},"score":1,"resource":{"primary":{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.67.10.17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,6]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,8,3]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.67.10.17","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,6]]}}}